A study by researchers at the University of Seville found that individuals with lower levels of education are 10.32 times more likely to commit violent crimes than those with high educational levels. Additionally, prisoners diagnosed with functional mental illness were 3.5 times more likely to commit or attempt murder.
Researchers have discovered how Leishmania donovani uses physiological response to low oxygen levels to establish a chronic infection. The parasite induces the expression of HIF-1α, a master regulator of cellular response to hypoxia, in monocytes and macrophages.
Monitoring blood levels of infliximab in IBD patients before loss of efficacy is associated with improved outcomes, including lower rates of surgery and hospitalization. This approach is linked to reduced treatment failure, infusion reactions, and need for IBD-related surgery or hospitalization.
A new study analyzing medieval skeletons found that contracting leprosy increased a person's chances of dying, but social status and sex also played roles. The researchers created a model to explore morbidity and mortality through a unique data set, shedding light on the complexities of the disease in the past.
A new iPhone app called MS Mosaic aims to improve multiple sclerosis management by tracking patients' daily and weekly symptoms. The app collects data through various surveys, performance tests, and wearable device integration, providing insights for more tailored treatment.
Researchers developed a machine to automate soybean quality evaluation during harvesting, providing real-time grain quality information. The system uses high-speed camera and computer program to analyze beans in real time, allowing operators to make adjustments as they go.
US breast cancer death rates are decreasing overall, with a 39% drop since 1989. Black women still face higher mortality rates than white women, but several states have seen significant declines in the gap between the two groups.
Researchers discovered a mechanism by which gut bacteria contribute to hypertension, involving the breakdown of cortisol into a molecule called GALF. This process can lead to an increase in blood pressure. The study aims to develop targeted therapies to combat hypertension.
A new study has found that trastuzumab treatment does not increase the risk of surgical site complications that require intervention after breast reconstruction. Immediate breast reconstruction may be possible for patients receiving trastuzumab alone, but those on combination targeted HER-2 treatment should delay surgery.
A parenting program strengthening skills also improves ADHD symptoms in 3-8 year-olds, according to researchers. The 'Incredible Years' Basic Parent Program demonstrates sustained improvements for children's behavior difficulties and social skills.
A team led by University of Iowa physicist Craig Kletzing has won $1.25 million from NASA to conceptualize a potential mission to study the interactions between the sun and Earth's magnetic fields. The mission, called TRACERS, aims to better understand how the solar wind affects our planet and its technology.
A new cardiac catheter combines fluorescence lifetime imaging (FLIm) with intravascular ultrasound to measure plaque composition, providing a more accurate prediction of heart attacks. The device has been tested in living swine hearts and human coronary artery samples, showing promising results.
Scientists have designed a new single-site catalyst that speeds up the rate of water oxidation, releasing protons and electrons that can be used to create hydrogen fuel. The catalyst improves upon previous designs, achieving a comparable rate to natural photosynthesis per catalytic site.
Researchers at Georgetown University Medical Center discovered a novel agent YK-4-279 that, when combined with vincristine, halts the ability of Ewing sarcoma to grow and progress. The combination produces a microtubule catastrophe in cancer cells, targeting their ability to divide and multiply.
A fecal transplant from a lean donor can temporarily improve insulin resistance in obese men, but only half of the recipients responded. The success of the treatment depends on each patient's fecal gut-bacterial makeup, which can be predicted through analysis.
Researchers at NIH uncovered the first evidence of a brain lymphatic system, suggesting vessels act as a pipeline between brain and immune system. The discovery uses MRI to scan brains of healthy volunteers and confirms results in human and nonhuman primate brains.
The Joslin Diabetes Center has been awarded $8.2 million from the National Institutes of Health (NIH) in continued support for its Diabetes Research Center program. The funding will enable researchers to advance treatments and potentially find a cure for diabetes.
A study published in Developmental Psychology found that socially active youth have higher expectations for their careers and are more likely to attain prestigious jobs. Researchers suggest that educators provide spaces for students to reflect on and challenge inequalities, leading to improved engagement and learning outcomes.
A review by UC Davis graduate students highlights the need for research on wildfire smoke's composition and its impact on human health. The study found that current scientific evidence is insufficient, and pesticides and fire-suppression chemicals used in California contribute to the toxic effects of wildfire smoke.
Scientists discovered a prehistoric squid's remains in the stomach of a nearly 200-million-year-old newborn ichthyosaur. The young ichthyosaur was around 70 cm long and had a complete set of bones, making it exceptionally well-preserved.
Researchers at Florida State University found that the heaviest and rarest elements do not follow traditional rules of quantum mechanics. Instead, Albert Einstein's Theory of Relativity governs their behavior, revealing unusual chemistry patterns. The study sheds new light on these lesser-known elements.
A new report by the University of Oxford evaluates claims about grass-fed beef and its impact on greenhouse gas emissions. The study finds that while grazing can sequester carbon, this effect is time-limited and outweighed by emissions at the global level.
Researchers have discovered evidence of dynamical dark energy, suggesting that the nature of dark energy may not be a constant vacuum energy. The discovery was made possible by high-precision measurements of Baryonic Acoustic Oscillations and will require confirmation from next-generation astronomical surveys.
Researchers have identified a distinctive epigenetic event in immune cells that differentiate in the tumoral microenvironment, making them tolerant to cancer cells. The study found that DNA methyltransferase 3A is responsible for the acquisition of suppressive properties in these cells.
Researchers found that large-scale pheasant release programs have not changed the birds' roadkill likelihood, but shifted peak times to autumn and late winter. Captive-bred pheasants lack survival skills after release, making them vulnerable to road accidents.
Researchers develop heat-treated magnesium alloy that outperforms titanium in implant applications, promoting bone growth and stability while avoiding complications like infection and corrosion. The T-5 alloy shows superior mechanical properties, lower degradation rates, and limited risks of rejection or infection.
Researchers found that super-powerful quantum computers must be even more powerful than previously thought to outperform ordinary PCs. The team simulated boson sampling for 20-50 photons on laptops and servers, pushing the boundary of what is possible.
A new study found that Twitter is a hub of anti-vaccine sentiment, particularly in affluent regions. The research used machine-learning algorithms to analyze over half a million tweets between 2009 and 2015, finding that half of online discussions about vaccines were negative.
Researchers from Georgia Institute of Technology found that elevated ammonia levels in Beijing have a relatively little impact on the acidity of pollutant particles. They suggest that sulfur dioxide and nitrogen oxide could be more significant contributors to extreme haze, which is linked to human health risks.
Researchers found that migratory female butterflies make distinct physiological changes to invest in flight over reproduction during migration. They remain reproductively inactive and carry a lighter abdomen to optimize energy use. This strategy allows them to breed at the end of the migration, producing large numbers of eggs.
A new study reveals that livestock grazing has damaged one-third of giant panda habitat in the park, with bamboos being a crucial food source. The degradation coincides with a nine-fold increase in livestock numbers over 15 years, driven by factors such as increased consumer demand for meat and unclear government policies.
A new study from Drexel University found that incorporating diverse ideas from women can improve safety in traditionally male fire departments. However, female firefighters often face hostile cultures and feel unwelcome due to hypermasculine environments. This can lead to a lack of reporting of injuries, which can be career-ending.
New simulations show that limiting local coordination between swarming animals improves group survival and information spreading. Researchers at SUTD discovered a parallel between collective evasive maneuvers and the spread of information in social networks.
Researchers tested the KiVa program to reduce bullying and victimization in US schools. Results showed significant reductions in bullying, but implementation was limited by factors such as teacher burnout and lack of resources. Improving teachers' workloads and reducing burnout may lead to better outcomes.
Researchers will use state-of-the-art imaging techniques to gain new insights into neural circuit function, critical for addressing visual and neurological disorders. The grant aims to fill a major gap in understanding how neurons process information, crucial for treating brain-related conditions.
Researchers at Mount Sinai Hospital discovered a genomic recipe in rare benign tumors that can regenerate insulin-producing human beta cells, potentially treating diabetes. The study's findings have the potential to develop new drugs that increase healthy beta cell mass.
A recent Oregon study with zebrafish found that transmitted microbes lead to similar gut microbiomes, selecting for particular microbes that are good at moving from fish to fish. This suggests the movement of microbes may drive microbiome variation and could impact human health.
A new user-friendly interface allows cell biologists to create complex biological models using the Virtual Cell supercomputer, expanding access to modeling capabilities. The updated version of VCell enables users to define molecules and explain interactions with minimal coding, reducing complexity and increasing usability.
KAUST researchers have demonstrated a scalable, efficient alternative technology to traditional electrical transistors, using mechanical vibrations excited by multifrequency electrical inputs. This novel technique enables the cascading of logic gates, resulting in lower complexity and higher integration densities.
A global research team of 22 scientists has created a comprehensive glossary of terms to describe cellular processes in plants, aiming to clarify confusion among experts. The lexicon covers key structures and processes involved in cytokinesis, a crucial phase of cell division that could accelerate breeding for sustainable materials.
A landmark study found that regular exercise can prevent future depression and that even small amounts of physical activity can deliver significant protection. The research involved 33,908 Norwegian adults and showed that 12% of cases of depression could have been prevented with just one hour of physical activity per week.
A new biomarker detects Alzheimer's disease in its preclinical phase, identifying individuals with impaired neuropsychological and neurophysiological functions. The discovery has high accuracy and sensitivity, offering a promising approach to early diagnosis and treatment.
Researchers identified a tiny viral protein, 3B3, that plays a key role in the replication of foot-and-mouth disease virus. This discovery could lead to the development of more effective vaccines against the disease.
A team of 98 scientists from 22 countries compiled a comprehensive database of past global temperature records spanning 1 CE to the present. The PAGES2k 2,000 Year Multiproxy Database contains 692 records from 648 locations, providing the largest body of climate records with high temporal resolution.
A study by Lancaster University found that women with troubled childhoods are more likely to have their children removed by the courts. Despite challenges, many women were able to turn their lives around and care for new babies with support from new partners and positive relationships.
A study by The Lancet Public Health found that US women must travel an average of 11 miles to access an abortion clinic, but one in five would need to travel over 43 miles. This disparity is particularly pronounced in rural areas, where some women face distances exceeding 180 miles for access.
The LIGO team detected gravitational waves from colliding black holes, providing a new way to explore the cosmos. Advanced optical interferometers enabled these breakthroughs, allowing scientists to study powerful astrophysical events.
Researchers found that two species of pumpkin toadlets produce sounds outside their hearing range due to an undeveloped inner ear, indicating they are insensitive to the sound of their own calls. This finding suggests that these frogs may be evolving towards a loss of acoustic communication.
Researchers found significant differences in diet between those buried in dolmens and caves, suggesting possible socioeconomic differences. The study used stable carbon and nitrogen isotopes to analyze bone collagen and found a more diverse diet in cave burials.
Research reveals eight mental models used by teachers to construct STEM-based lesson plans, highlighting the need for better understanding of STEM education's value and online classroom design. Implementing teacher leadership techniques in digital classrooms also improves communication patterns.
Research led by Dr. Carlos Arteaga has identified potential targets for treating chemotherapy-resistant triple negative breast cancer, including genes MCL1 and MYC. These genes can be targeted with specific drugs to slow or prevent chemotherapy resistance, improving the outlook for this aggressive form of breast cancer.
A new study found that surgical cancer centers in England are investing heavily in unproven technologies to stay competitive, despite a lack of evidence on their effectiveness. This trend has led to the closure of several centers, with patients often traveling to alternative facilities offering robotic surgery.
A study examining HIV virulence and its effect on the human immune system found that both CD4+ T cell decline and per-pathogen pathogenicity are heritable from donor to recipient. Heritability rates revealed a significant 17% impact, indicating that viral genotype plays a crucial role in infection severity.
A geochemist from MSU has assessed the oxidative environment and its changes inside asteroids from core to surface. The study reveals that variations in asteroid composition and structure significantly impact oxygen pressure.
Researchers will investigate how individual differences in stress response affect escalation of alcohol drinking after traumatic stress, with potential treatments for vulnerable populations. The study aims to identify neurobiological targets for treating alcohol abuse in PTSD patients.
Researchers at Ames Laboratory have successfully decomposed lignin into stable components using a phosphate-modified ceria catalyst, producing useful industrial precursors for nylon production. The process eliminates the need for hydrogen from natural gas and uses an energy-conserving alcohol-based hydrogenation process.
The durian tree relies on the pollination services of the island flying fox, which is critically endangered. The discovery has significant implications for Southeast Asia's tropical ecosystems and the lucrative durian industry.
A new study from the University of Colorado Denver finds that medical scribes significantly decrease patient wait times by about 13 minutes per patient. The presence of a scribe also reduces the time physicians spend completing patient charts, lowering overtime costs for emergency departments.
Researchers at King Abdullah University of Science & Technology (KAUST) have discovered a unique reaction pathway that utilizes molten sodium-based catalysts to efficiently convert natural gas into industrial products. The catalyst, which forms hydroxyl radicals from oxygen and water, has great potential for various catalytic reactions.
Researchers used historic accounts and modern methods to describe an extreme magnetic storm over Kyoto in the 18th century. The study provides valuable insights into past solar activity and its potential impact on future events.