Research found that four molecular subtypes of gastric cancer have different prognoses and responses to chemotherapy, with the EBV subtype associated with the best outcome and the GS subtype with no benefit. The study suggests that classifying gastric cancer cases by subtype could provide personalized treatment options.
Researchers identify major transitions in human cultural evolution using computational methods and large cross-cultural datasets. The study reveals the complex processes underlying our cultural histories, including changes from small kin-based groups to colossal nation states.
A study found that kidney transplant recipients have a higher incidence of melanoma compared to the general population, with risk factors including older age, male sex, and white ethnicity. Long-term immunosuppressive therapy contributes to this increased risk.
The Howiesons Poort tradition, dating back to 66,000-59,000 years ago, demonstrated that early humans could exploit new environments despite pronounced aridification. The development of cultural innovations such as the bow and arrow, engraving ostrich eggshells, and intensive hunting practices allowed HP populations to thrive.
Researchers at Osaka University develop new method to create submicron structures on silicon surfaces, reducing reflection and increasing infrared light capture. The approach improves power conversion efficiency of solar cells while keeping manufacturing costs low.
Researchers discovered a massive predatory fish species called Birgeria americana in Nevada's Early Triassic fossils, rewriting the history of apex predators. The find shows that marine ecosystems recovered faster than previously thought, and temperature conditions were suitable for life near the equator.
Researchers at Brookhaven National Laboratory have discovered a new behavior by electrons in high-temperature superconductors, challenging a cornerstone of condensed matter physics. The symmetry-breaking flow of electrons persists up to room temperature and across the range of chemical compositions examined.
Researchers developed a new approach to model human immune variation, identifying gene markers that correlate with human disease outcomes. The study found that accounting for immune diversity is critical for predicting disease outcomes.
Scientists have identified a crucial mechanism by which cells detect and respond to DNA damage, shedding light on the body's natural surveillance systems. This discovery may help explain how the human body keeps disease in check and could lead to new therapeutic approaches for cancer prevention.
A team of archaeologists discovered lipid-based biomarkers for whole wheat in a frozen Bronze Age container, providing new insights into the spread and exploitation of cereal grains. The finding has significant implications for studying early farming practices in Eurasia.
A study of 154 individuals with near-death experiences found that while common phenomena like feeling peacefulness and seeing a bright light occur frequently, the order of appearance varies greatly between participants. The most commonly reported sequence was out-of-body experience followed by a tunnel, bright light, and finally peace.
A randomized trial found that incorporating 12-step program elements into adolescent substance-use disorder treatment resulted in significantly reduced substance-related consequences. Participants in the integrated program also reported higher rates of 12-step meeting attendance, associated with longer periods of continuous abstinence.
Soil scientists have developed a new method to observe water transport in soil and plant roots, enabling the first-ever 3D mapping of this process in just 10 seconds. This breakthrough technology could also be applied to study fuel cells, batteries, and construction materials.
A study by Hirojuki Hikichi and colleagues found that group relocation increased informal socializing and social participation among older adults. Nearly three years after the disaster, respondents who relocated with their community showed increases in meeting with friends and participating in sports clubs.
A new study found that the combination of nivolumab and ipilimumab therapy demonstrates manageable safety, notable antitumor activity, and durable responses with promising long-term overall survival in patients with metastatic renal cell cancer. The treatment shows enhanced antitumor activity compared to monotherapy in tumor types such...
A large new study shows that only one in three patients who have bariatric surgery succeed in getting their body-mass index below 30 in the first year. Patients with lower BMIs before surgery had higher odds of achieving this goal and better health outcomes, including stopping medication for high blood pressure and cholesterol.
Researchers developed a light-responsive crystalline material that overcomes previous challenges in creating 'photoresponsive' materials. The material changes its porous nature when exposed to light, allowing for repeatable and reversible changes.
Researchers investigate how climate change and environmental toxins affect the world's largest freshwater lake. Studies on amphipods found that temperature increases can be catastrophic for some species, while chemical pollution can have mass impacts on individual species and ecosystems.
Soft robotic exosuits have been developed to assist stroke patients in walking with more efficiency and reduced asymmetry. The devices provide forward propulsion and correct problems with ankle dorsiflexion, a common issue affecting up to 20% of stroke survivors.
New research highlights the importance of diffusion gradients in regulating stem cells and tissue development. The study explores how gas and nutrient concentrations influence stem cell potency, differentiation, and metabolism. It also introduces novel models for understanding diffusion processes in three-dimensional tissue constructs.
A pair of new computational methods developed by researchers from MIT, University of Toronto, and Adobe Research generate simulations that match real-world behaviors at rates 70-times faster than previously possible. These methods can automate the design process used to create dynamic mechanisms for controlled jumping.
Researchers at VCU Massey Cancer Center have found a potential cure for colon cancer by targeting the gene CtBP with a drug called HIPP, which reduces pre-cancerous polyps by half and increases mouse lifespan. This breakthrough may also extend to other cancers depending on the same mechanism.
Researchers at Northwestern University discovered that up to half of the Milky Way's matter may have originated from distant galaxies through intergalactic transfer. This phenomenon, identified in simulations, shows that gas flows from smaller galaxies to larger ones, such as the Milky Way, forming stars.
Tropical Depression Greg appears as a low-swirl of low clouds with some patches of convection on July 26. It is moving west at 12 mph and has sustained winds near 30 mph, forecast to become a remnant low later.
The Mathematical Association of America has honored top math educators for their effective teaching methods and impact on undergraduate education. The Henry L. Alder Awards recognized Steven Klee and Mary Beisiegel for their exceptional teaching and mentoring skills.
A recent study found that managers in various industries overestimate customer satisfaction, relying on unrealistic expectations for marketing decisions. This leads to underinvestment in quality improvements and a failure to address marketplace issues effectively. The study suggests that existing customer feedback systems are not perfo...
A new extinct bird species, Pyrrhula crassa, has been discovered on Graciosa Island in the Azores archipelago. The species went extinct due to human colonization and introduction of invasive species. Its unique beak morphology suggests it was a large bullfinch species.
A recent study published in The BMJ found a significant association between e-cigarette use and increased smoking cessation rates among US adult smokers. E-cigarette users were more likely to make a quit attempt and succeed in quitting for at least three months compared to non-users.
The Magic Bench enables users to see, hear, and feel animated characters in a shared 3D space. Researchers have created a platform that combines augmented and mixed reality for a seamless experience.
The nonprofit International Partnership for Microbiddles (IPM) will receive a competitive award of up to $25 million from the United States Agency for International Development (USAID) to advance HIV prevention microbicide products for women. The award supports IPM's monthly dapivirine vaginal ring, which has shown promising results in...
Tropical Storm Nesat has formed east of the Philippines with maximum sustained winds near 45 knots (52 mph), strengthening at a rate of 4.6 mph per hour. The storm is expected to move past the Philippines without making landfall, intensifying to 85 knots before approaching Taiwan by July 30.
Researchers at Texas A&M University have developed a new method for propagating light through human tissue, enabling deeper brain imaging and potential applications in medical imaging and driving safety. The technique involves making tiny holes to pass light through, increasing optical transmission by a factor of 100.
ASTRO honors Edith Peterson Mitchell, MD, a leading researcher and medical oncologist, for her work on chemoradiation treatments. Her research has helped raise the profile of radiation oncology by providing clinical evidence for combined modality treatment.
Researchers developed a simple, cost-effective way for hospitals to increase their capacity to contain airborne illnesses. By sealing off a hospital wing and adjusting ventilation systems, hospitals can reduce the spread of diseases. The new solution enables small community hospitals to prepare for rapidly spreading airborne illnesses.
A new study has found that an alternative method of pain relief for knee replacement surgery reduces the need for powerful painkillers like morphine. The new approach involves injecting anaesthetic agents around the knee joint, administered by the surgeon without specialist equipment.
Researchers have found that bacteria can use mechanical cues to maintain their shape and recover from deformation. The study, published in Nature Microbiology, shows that Escherichia coli uses mechanical strain to grow its cell wall and recover its shape after being twisted out of shape.
Researchers analyzed projectile points to find evidence of increased experimentation in tool production, suggesting a decrease in social interactions among North American populations. The findings provide insights into the changing hunter-gatherer social dynamics during this period.
A Kansas State University-led team will use the grant to establish a cognitive and neurobiological approaches to plasticity center, supporting research on brain development, cognitive flexibility, and aging-related impairments. The center will also renovate laboratory facilities and recruit new faculty members.
Researchers used a powerful electron camera to study the motion of atoms in perovskite materials, discovering that light causes unusual deformations that could enhance their efficiency. These findings provide clues for making better solar cells.
A team of astronomers detected a massive star's titanic explosion and measured its development and decay in unprecedented detail. The findings provide strong evidence for one of two competing models for how gamma-ray bursts produce their energy, with the data showing powerful magnetic fields confining and directing the radiation.
Researchers analyzed recent progress in lithium-ion technology and suggested ways to make batteries adaptable for challenging conditions. The study mapped the performance of various materials in high-temperature batteries, highlighting opportunities for improvement.
The study analyzed three current methods of mixed population capture and found serious quality problems with all three approaches. It suggests continuing 'multi-ticking' in the US and Canada with clearer instructions for respondents as a potential alternative to 'exact combinations' method.
A five-year research programme is improving care for patients living with dementia in hospitals. Distractions during drug rounds can hinder treatment, but the involvement of family or carers can be hugely beneficial. The study's findings aim to create and implement specific care pathways that acknowledge differences in dementia present...
NASA closely monitored Hurricane Hilary's development, noting its compact nature with winds extending 15 miles from the center. The storm was forecast to move westward at 13 mph, with some slowing down over the next couple of days.
Researchers developed a lightweight, soft wearable ankle-assisting exosuit that can reinforce normal gait in people with hemiparesis after stroke. The device improved walking performance and reduced energy costs in patients post-stroke, showing promise as a rehabilitation tool.
Researchers developed a method to observe local conductivity changes in memristors using conductive liquid electrolytes. The method reveals the formation of nanoscale spots responsible for conductivity changes, allowing for distinction between electrical and thermal contributions.
Researchers have identified a cyclic peptide that can bind to hair under shampooing conditions, increasing the deposition of fragrance compounds. This results in stronger fragrance smells on hair for up to 24 hours after shampooing.
Neal Katz, a theoretical astronomer at UMass Amherst, has received a Fulbright Scholarship to study and teach galaxy formation in collaboration with colleagues in South Africa. He will use computer simulations to advance understanding of galaxy formation and analyze data from the MeerKAT radio telescope.
Research suggests that individuals with a family history of bipolar disorder may experience faster biological aging. The study found that patients treated with lithium had longer telomeres, which could help reverse age-related changes. This association may explain the higher rates of aging-related diseases among bipolar disorder patients.
Researchers developed a technique that uses robotic arms to immerse objects in water, measuring volume displacement for volumetric shape representation. This method achieves more accurate 3D scanning than current methods, particularly for complex objects with hidden parts.
The Affordable Care Act (ACA) has helped close gaps in healthcare access between poor and higher-income households. In states that expanded Medicaid, the gap fell by 46%, while in non-expansion states, it declined by 23%. Despite gains, many low- and middle-income residents still lack coverage or avoid care due to cost.
Scientists discover dodder parasite transmits insect feeding-induced signals among different hosts, triggering defense reactions in neighboring plants. The parasitic plant's vascular system connects with its hosts, enabling the transfer of warning signals.
Scientists have developed a high-resolution microscope to directly observe kinesin motors moving along microtubules, revealing the coordination of attachment and release. This new understanding may help clarify defects in transport processes contributing to diseases such as Alzheimer's and ALS.
Nearly 60% of mechanical thrombectomies occur during non-work hours, with peak periods between 8-11 p.m. The study emphasizes the importance of understanding procedure timing to optimize patient outcomes and optimize physician staffing at stroke centers.
A study found that adolescents with an increasing pattern of marijuana use over their teens had the greatest dysfunction in brain reward circuitry, highest rates of depression, and lowest educational achievements. The findings highlight the importance of understanding marijuana use across adolescence to predict long-term impacts.
A new study found that higher levels of daily physical activity were associated with better performance on cognitive tasks, particularly attention, memory, and multitasking. Exercise was linked to reduced fatigue, which in turn improved cognitive function.
A team of researchers from Monash University has identified the Nkx2.5 gene as a key regulator of wing development in emus. This discovery sheds light on the genetic basis of limb reduction and may have implications for human limb development, particularly in individuals born with limb abnormalities.
A CU Cancer Center study found that retinoic acid may fail against breast cancer cells marked by protein CK5 due to progesterone's promotion. Treatment timing might be crucial in preventing the growth of these dangerous cells.
Research reveals that dodder plants transmit herbivory-induced signals among host plants, triggering defense responses and reducing insect growth. The discovery showcases the complex ecological interactions between parasitic plants and their hosts.
Researchers found that middle-aged participants with higher levels of lutein had neural responses more similar to those of younger individuals. This suggests that lutein may have cognitive benefits for early life stages. The study aimed to understand how diet impacts cognition throughout the lifespan.