Researchers at Carnegie Mellon University developed a new method to improve chemotherapy nanodrug delivery by using an FDA-approved nutrition source. This approach reduces toxic side-effects and increases the amount of drugs reaching tumor cells.
A research team led by David Brankovits discovered that cave-adapted organisms can thrive on methane gas and bacteria near it, raising the possibility of similar life forms existing worldwide. The study found a complex food web involving tiny organisms and large shrimp.
An international team of researchers discovered a previously unrecognized genus of extinct horses in North America, diverging from the main trunk of the Equus family tree around 4-6 million years ago. The new species, Haringtonhippus francisci, was a widespread and successful species that survived until roughly 17,000 years ago.
The new printer can print objects up to 10 times faster than existing commercial counterparts due to its compact printhead design. The team used a screw mechanism and laser to speed up the printing process, enabling it to fabricate detailed objects in several minutes.
The Vega de Granada area in SE Spain sinks up to one centimeter per year during dry periods. This land subsidence is caused by the exploitation of the aquifer and is a concern for village residents.
Researchers at NIST develop a new approach to testing multilayered, three-dimensional computer chips using microwaves. This method provides real-time insight into material performance and defects, potentially reducing electromigration issues and improving chip stability.
Researchers identified several lncRNAs linked to ovarian cancer, including DNM30S, which correlates with worse survival rates. Targeting these lncRNAs may represent a viable treatment strategy for ovarian cancer.
Scientists at Boston Children's Hospital have identified the molecule responsible for releasing interleukin-1 (IL-1) from immune cells. The study found that gasdermin D enables IL-1 release without killing the cell, which could lead to more potent and long-lasting vaccines.
A study of 42,230 adults found that delaying surgery for hip fracture beyond 24 hours was linked to a small but significant increased risk of death. Patients who had surgery within 24 hours had a lower risk of complications such as heart attack and pneumonia compared to those who waited longer.
A new technique using machine learning can improve the diagnosis of melanoma by identifying the optimal amount of context around skin lesions. By segmenting images into two parts, separating the lesion from surrounding skin, researchers found that a limited border beyond the lesion enhances classification performance.
Researchers from Children's Hospital of Philadelphia highlighted racial disparities in bystander CPR methods and found that children with hypertrophic cardiomyopathy are at risk for sudden cardiac death. Targeted training may increase bystander CPR rates and improve outcomes.
Researchers at The Feinstein Institute discovered dozens of genetic variations linked to general cognitive ability. These findings have the potential to aid in targeted treatment for cognitive disorders, including Alzheimer's disease, schizophrenia, and attention deficit hyperactivity disorder.
A new study published in the Journal of the American Medical Association shows that Fecal Microbiota Transplant capsules are just as effective as colonoscopy in treating C. difficile infections. The capsule delivery method is non-invasive, less expensive, and has no risks associated with sedation.
Scientists at Bielefeld University and University of Münster are studying how animals adapt to their environment through individualised ecological niches. They explore the genetic and behavioral factors influencing these adaptations.
Researchers at the University of Bristol created a new platform for producing desperately needed antibiotics by combining synthetic biology with biology and chemistry. The team successfully generated a semi-synthetic pleuromutilin derivative with enhanced antibiotic activity, addressing the growing resistance to existing antibiotics.
A Sydney team has invented a microcircuit based on Nobel Prize research, miniaturizing a crucial component for quantum computing. This innovation could pave the way for large-scale integration of quantum circuits and manufacturing in massive quantities.
A James Cook University study found nearly three quarters of office workers believe there is a negative relationship between sitting down all day and their health. The study suggests that education on the benefits of standing and buy-in from management are crucial to implementing effective behavior change strategies.
A new study found that weight loss through diet and exercise significantly slows down the degeneration of knee cartilage in obese individuals. However, weight loss achieved solely through exercise had no significant impact on cartilage degeneration, suggesting that a balanced approach involving diet is crucial for protecting the knees.
Researchers identified 100 undisturbed reefs with potential to provide coral larvae to damaged areas, promoting regional recovery. Effective local protection is crucial to support this ecosystem's resilience.
A study by UTSA researcher Seok Kang found that instrumental motives, such as purchasing tickets or buying merchandise, predict behavioral loyalty among fans. Ritualistic motives, like relaxation and social interaction, are associated with attitudes toward teams or players.
A new study published in Heliyon found that the cultural identity of rugby players affects their playing style, with players from diverse teams showing more serious and goal-oriented personalities. In contrast, players from homogeneous teams like the Māori All Blacks were more playful and spontaneous.
A new study analyzed breast cancer tumor samples over time, revealing common characteristics among treatment-resistant tumors. The research aims to understand tumor changes in real-time to adjust treatment accordingly.
A new therapeutic paradox targets thrombo-vascular complications in kidney disease by boosting a regulatory protein called STUB1, which interacts with tissue factor to trigger clotting. This approach may offer an alternative to standard heparin treatment while maintaining a balance between pro-clotting and anticoagulant factors.
A new study finds that prenatal stress during late gestation reduces offspring growth during dependence, resulting in a reduced body size throughout development. In contrast, early prenatal stress accelerates growth and increases size after weaning to ensure reproduction before death.
A new study from the University at Buffalo School of Management found that patient education and transparency are crucial in getting patients to share their medical records electronically. By making patients aware of existing privacy policies and security measures, healthcare providers can create an environment where patients feel comf...
A new study published in The Lancet Diabetes & Endocrinology found that diabetes and being overweight or obese are responsible for nearly 800,000 new cancer cases globally. High BMI was linked to twice as many cancers as diabetes, with liver cancer and endometrial cancer being the most common types.
The number of doctors specializing in nursing home care has risen by over a third between 2012 and 2015, according to a new study. This trend suggests the emergence of a significant new specialty in medical practice, but its impact on patient outcomes and continuity of care remains uncertain.
A study found that fecal transplant using oral capsules was as effective as colonoscopy in preventing recurrent Clostridium difficile infection. The treatment prevented CDI recurrence in 96% of patients after 12 weeks.
Researchers found that perceived risk of a romantic relationship ending influences the intensity of love and commitment, leading to reduced feelings when facing high or low risks. Commitment is strongest when there's only a moderate chance of break-up.
The European Research Council has awarded €630 million in Consolidator Grants to 329 top researchers across Europe, creating an estimated 2,000 jobs and funding research projects in physical sciences, life sciences, social sciences, and humanities. The grants are aimed at boosting the EU's scientific excellence and competitiveness.
A new study by Imperial College London and the Indian Institute of Technology Kanpur reveals that ancient Indus Civilization urban centers didn't need an active river system to thrive. The research found that a major Himalayan river, the Sutlej River, changed course eight thousand years ago, leaving behind an abandoned river valley occ...
A study suggests that expanding sugarcane cultivation in Brazil for ethanol production could reduce global carbon dioxide emissions by up to 5.6% by 2045, while replacing up to 13.7% of world crude oil consumption. The expansion of sugarcane cultivation is proposed in areas not under environmental protection or reserved for food produc...
A risk score identifies children at low risk for submersion-related injury who can be safely discharged from the emergency department. The Pediatric Submersion Score is a proposed guideline developed using sophisticated statistical methods, providing valuable information for future management of low-risk childhood submersion.
Researchers from the National University of Singapore have successfully demonstrated room temperature magnetisation switching driven by giant SOTs in topological insulator/conventional ferromagnet heterostructures with an extremely low current density, overcoming scalability and power consumption issues.
A new report highlights the benefits of health literacy for both patients and providers, achieving the quadruple aim of quality care, community health, reduced costs, and improved patient and provider experiences. Health literacy can improve patient outcomes, reduce hospitalization rates, and lower health expenditures.
University of Miami Assistant Professor Elizabeth Simpson challenges a 2016 study that claims human babies do not imitate, citing flaws in methodology and presenting evidence of neonatal imitation. Her research suggests that imitation is a marker of healthy social development in infants.
Researchers found a strong inverse relation between magnetic field strength and star formation rate in molecular cloud complexes. This suggests that magnetic fields slow down or stop the collapse of gas clouds to form stars, leading to fewer massive stars in galaxy centers.
Researchers at UT Southwestern Medical Center identified a critical link between obesity and type 2 diabetes, finding that insulin delivery is impeded due to abnormal immunoglobulins. The study may lead to new strategies for diabetes risk screening and prevention.
A study published in International Studies Quarterly found that countries tend to behave more aggressively in international affairs after experiencing surges of nationalism from international sports. This includes cases such as the 1969 Soccer War and the 2016 English-Russian Euro riots, where military or political conflicts arose betw...
Researchers found that patients with more mutations in their tumors had better survival rates after adoptive T cell therapy. The treatment, which sharpens T cells to fight cancer, showed promising results but also many side effects.
Scientists have discovered a cryptic ecosystem in Mexico's Yucatan Peninsula, where methane and bacteria form the basis of a food web dominated by crustaceans. The study provides a model for coastal groundwater ecology and establishes a baseline for evaluating the impact of stressors on these ecosystems.
Babies exposed to antibiotics for GBS developmentally delayed gut bacteria, which recovered by 12 weeks of age. Long-term effects on infant health are unclear.
A recent study found that most smokers feel regretful about their habit and are addicted to cigarettes. The researchers suggest that measures reducing smokers' discontent and improving subjective well-being could be considered in cost-benefit analysis of proposed regulations.
Researchers from University of Houston release open-source dataset and instructions for building a smartphone microscope with an inexpensive inkjet-printed elastomer lens. The device can perform fluorescence microscopy, detect waterborne pathogens, and has potential applications in rural areas and developing countries.
Researchers at USC's Keck School of Medicine identified a human protein that restricts herpes virus replication, potentially preventing cancer. The study mapped healthy cells and those infected by the large DNA virus, shedding light on the disease pathway.
A study published in the Journal of Clinical Endocrinology & Metabolism found that continuous glucose monitors can protect against hypoglycemia episodes, even when the body's defense mechanisms are impaired. The devices raised awareness of low blood sugar threats and reduced severe episodes.
Scientists measured a time delay of 100 milli-seconds between X-rays and optical flashes from the jet emitted by V404 Cygni's black hole. This delay indicates the inner acceleration zone in the jet is approximately 30,000 kilometers away from the event horizon.
Midlife women are disproportionately affected by asthma due to testosterone's impact on ILC2 proliferation and airway inflammation. The study highlights the importance of sex hormones in treating respiratory diseases.
A study published in PLOS Medicine found that starting antiretroviral therapy (ART) immediately following an HIV diagnosis dramatically improves retention in clinical HIV care. Patients who were eligible for ART at diagnosis were 25 percentage points more likely to start therapy and 18 percentage points more likely to remain in care at...
Researchers discovered that coating nickel nanoparticles with silica shells fragments the material, creating a small core of oxidized nickel surrounded by smaller satellites embedded in a silica shell. The technique may prove useful for increasing the surface area of nickel available for catalyzing chemical reactions.
A new study found that fat distribution patterns, not just overall weight, are linked to heart attack risk in women and men. Women had higher subcutaneous fat but lower lean mass compared to men, who had more visceral adipose tissue and ectopic fat.
Researchers developed a powerful new computer model that replicates the biological activity within the heart preceding sudden cardiac death. The model has yielded important clues for developing treatments, identifying key molecular factors associated with arrhythmias.
Researchers from USC discovered that the levels of Hedgehog protein determine whether cells form bone or cartilage in developing ribs. High Hh concentrations favor bone formation, while lower concentrations promote cartilage growth.
Research at National Research University Higher School of Economics found that international students with internal motivation and autonomy experience less culture shock and higher subjective well-being. Conversely, those driven by external factors struggle to adapt. The study's findings can inform preparation strategies for students s...
A study of over 13,000 opioid overdose deaths found that individuals with chronic pain conditions were at the highest risk of death. The study also reveals that many who died had been diagnosed with depression and anxiety, highlighting the importance of early intervention for those at high risk of fatal overdose.
A study published in Academic Emergency Medicine found that prehospital use of supraglottic airways is linked to better neurological outcomes in cardiac arrest patients who receive cardiopulmonary resuscitation. The study suggests that SGA may improve oxygenation, supporting its continued use in emergency medical services.
Scientists at NREL have developed a switchable solar window that converts sunlight into electricity while maintaining transparency. The device uses thermochromic materials and has an average light transmission of 68% in its transparent state.
Researchers at NIAID found that some patients' seemingly inexplicable anaphylaxis was caused by an uncommon allergy to a molecule found naturally in red meat. Six study participants tested positive for an allergy to galactose-a-1,3-galactose, or alpha-gal, and experienced no anaphylaxis after implementing diets free of red meat.
Biomedical engineers at Duke University have successfully grown a fully functional artificial human heart muscle large enough to patch over damaged tissue. The breakthrough enables therapies to replace lost muscle after a heart attack, which currently leaves patients with scar tissue that cannot transmit electrical signals or contract.
Researchers found higher sodium concentrations in the cerebrospinal fluid of migraine patients compared to healthy controls, potentially aiding in diagnosis and understanding of migraines. The study used a novel magnetic resonance technique called cerebral sodium MRI to visualize sodium levels in the brain.