Dr. Joseph P. Mizgerd, a Boston University School of Medicine professor, has received an NIH award to study the biology of pneumonia, which kills more children worldwide than any other disease. He aims to advance lung defense against pneumonia and identify prevention strategies for chronic disease of aging.
Researchers using big data and CRISPR analyze the immune system's minute-by-minute response to viruses, revealing a step-by-step reaction. This approach provides crucial insights into how the body fights off infections.
Researchers at Oregon State University have discovered a new order of insect, Aethiocarenodea, featuring a 100-million-year-old specimen with a triangular head and alien-like features. The species has been named Aethiocarenus burmanicus and is believed to be an omnivore with special adaptations to survive in ancient forests.
The Danforth Center is expanding its research program to optimize breeding strategies for grain sorghum, a critical source of nutrition for millions in Sub-Saharan Africa. The grant will support the development and deployment of advanced phenotyping and breeding technologies.
Gabriela González, a professor at LSU and LIGO scientist, receives the 2017 Rossi Prize for her groundbreaking work on gravitational waves. Her discoveries have opened a new era in gravitational-wave astronomy.
Researchers demonstrate that artificial cells can communicate seamlessly with real cells through chemical signals, passing a basic laboratory Turing test. The artificial cells showed they could sense and respond to molecules from various bacterial species, including V. fischeri, E. coli, and P. aeruginosa.
AGU evaluates shifting science landscape and climate concerns, including air pollution's impact on desert southwest. Researchers also explore Mars' possible warming due to greenhouse effect.
Scientists discover that a minuscule change in brain connections between detecting hawthorn and apple odours may be the cause for the split amongst these fruit flies. This finding suggests that even small changes in nervous system can have significant effects on species, particularly in response to introduced foreign species.
A team of researchers at New Jersey Institute of Technology has developed spectral and co-spectral techniques to measure changes in subsurface water temperature and salinity. The methods, validated with a year's worth of data from two beaches in Alaska, can help coastal scientists anticipate changes in coastal ecosystems.
A recent study published in PLOS ONE found that diabetes accounts for 12% of deaths in the United States, significantly higher than previously thought. This increase is attributed to the growing prevalence of diabetes, which has risen by nearly 300% since 1980, affecting over 21 million Americans.
A new program, Early Check, offers free genetic testing for up to 120,000 families annually, aiming to improve health outcomes and scientific knowledge. The testing can help detect conditions like spinal muscular atrophy and fragile X syndrome, providing peace of mind for parents while also enabling research on potential treatments.
Scientists have successfully created a photonic chip that can emit directional photons, paving the way for complex quantum networks. This breakthrough enables full control over photons and has significant implications for quantum communication and information processing.
A preclinical model reveals that congenital heart disease disrupts cerebral oxygen supply, leading to reduced cortical growth and abnormal neurogenesis in the subventricular zone. Restoring NSPCs' neurogenic potential may help lessen long-term neurological deficits in children with CHD.
Patient navigators are a valuable resource for American Indians and Alaskan Natives with cancer, helping them overcome barriers to diagnosis and care. Researchers found that patients working with a navigator were almost four times more likely to have a definitive diagnosis within a year of an abnormal screening result.
Researchers at Nagoya University have uncovered a novel brain circuit for hunger responses during starvation, revealing the role of neuropeptide Y signals in controlling heat production by brown adipose tissue. The study found that inhibitory GABAergic inputs from medullary reticular neurons inhibit BAT thermogenesis.
Researchers found that fit female college students with normal iron levels achieved higher grade point averages than their unfit counterparts.
Researchers at UBC Okanagan campus found that safety codes can result in overly reinforced bridges, wasting materials and increasing construction expenses. The study suggests a new approach to seismic design, prioritizing self-centering capability and reducing the need for costly demolitions.
Researchers studied asteroid Chelyabinsk to determine properties necessary for deflection missions. The study found that an asteroid's composition, internal structure, density, and physical properties are crucial in determining the success of a kinetic projectile launch.
A new study found that adding bezlotoxumab to standard antibiotic treatment can reduce the risk of recurrent Clostridium difficile (C.diff) infections by 37%. This reduction in recurrent infections can lead to fewer hospital admissions, reduced costs for the NHS, and possibly a decrease in deaths.
A new study published in Experimental Physiology found that sprint interval training is a powerful stimulus to elicit cellular remodelling in both men and women. The research, conducted at McMaster University, showed that changes in gene expression over a short time-scale are similar between the sexes.
Researchers developed an acoustofluidic chip to concentrate fluorescently labeled biomarkers using ultrasound, enabling the detection of smaller particles and boost their signal. The technique shows promise for point-of-care diagnostic applications, including the potential analysis via smartphone apps.
The quadrivalent influenza vaccine (QIV) is expected to provide health benefits in most parts of the world by reducing the burden of influenza. By targeting all four circulating strains, QIV may reduce medical costs and save lives compared to the trivalent influenza vaccine (TIV).
Research from Iowa State University shows that video game ratings can effectively reduce violent play in children when used by parents to guide purchases and set rules. Parents who use the rating system and mediate their child's play are less likely to experience negative behaviors, such as acting out or misbehaving.
Researchers at the University of Illinois used a novel imaging technique to visualize microscopic shifts in metabolism and vesicle production in tumor cells. The study found that these changes can precede larger-scale events in the tumor environment, potentially preparing the way for cancerous cells to spread and metastasize.
Short bowel syndrome results in significant changes to gene expression, including increased cell proliferation and immune response. The study provides a map of these alterations, potentially leading to new therapies for SBS patients.
Researchers have quantified social genetic effects on over 100 phenotypes in laboratory mice, finding that up to 29% of variation is explained by the social environment.
A recent study published in the Journal of Agricultural and Food Chemistry found that stink bugs can contaminate wine with stress compounds, affecting its quality. The researchers discovered that pressing is a key step in releasing these compounds, and that limiting stink bugs to three per grape cluster could improve wine quality.
A new study finds that CMS and care providers lack predictive models needed to assess risks patients face after joint replacement. Hospital systems are apprehensive of getting penalized inadvertently because CJR's current payment model does not include a risk adjustment method.
Researchers have grown engineered heart tissue using a 3-D printer, improving heart function and decreasing dead tissue after a heart attack. The novel technique holds promise for the clinical use of 3-D-printing technology in preventing heart failure after a heart attack.
A new study reveals that anxiety in postmenopausal women is associated with increased severity of physical symptoms like hot flashes and sleep disruption. The study found a significant link between anxiety and urogenital symptoms, highlighting the importance of screening for anxiety to improve quality of life.
A new study found that delaying marijuana use until age 17 is associated with better brain function and fewer cognitive declines. Adolescents who started using cannabis earlier showed poorer verbal skills and vocabulary, as well as difficulties with problem-solving and daily adaptation.
Researchers found that nonresident seabirds concentrate their foraging efforts near Cordell Bank along the continental shelf break in Central California. This study identifies high-use foraging sites as a critical component of ocean conservation efforts.
A southern hemisphere moth species has been found to be resident in central Portugal, with a possible link to imported timber from South America. The species, Borkhausenia crimnodes, is likely to feed on decomposed plants and may exhibit invasive behavior.
Researchers have identified two specific dendritic cell groups, cDC1 and cDC2, present in human tumor tissues that stimulate strong anti-tumor immune responses. These cells show promise for developing innovative cancer immunotherapies by vaccinating tumors with the patient's own immune system.
A recent survey of primary care physicians found that 15% support the complete repeal of Obamacare, lower than the general public's percentage. The majority, 74%, favor changes to the law, such as creating a public option or increasing health savings accounts.
A systematic review found that healthcare providers frequently disagree on whether an individual is incapable of working. A new method, function-oriented assessment, has been developed to improve the assessment process for people with mental disorders.
The Bill & Melinda Gates Foundation has pledged $279 million to the University of Washington's Institute for Health Metrics and Evaluation (IHME) over the next decade. This investment will enable IHME to provide critical data on global health trends, informing policymakers' decisions and improving population health worldwide.
Researchers confirmed a theoretical possibility of dual liquid states in sub-zero water and other tetrahedral molecules. A study using DNA origami and simulation revealed that such structures could exhibit a high-density and low-density liquid phase, separated by an empty lattice.
A study published in Animal Behaviour documents changes in the 'alalā's vocal repertoire, including a reduction in alarm calls and territory broadcasts. This cultural shift may be related to differences in behavior necessary for survival in protected aviaries.
A randomized trial will investigate canagliflozin's effects on kidney function decline and provide benefits to diabetic patients. The study aims to slow kidney damage and inform treatment decisions.
A large international study has linked early puberty and childlessness to an increased risk of early menopause. Women who had their first period before age 11 were 80% more likely to experience premature or early menopause.
Researchers at San Francisco State University developed a new study that models nonresident seabird foraging distributions to inform ocean zoning. The study could help protect foraging seabirds along the Central California coastline and prioritize conservation efforts.
Researchers define how anti-cancer molecules work, binding to microtubules and destabilizing cell growth. The study's findings can be used to optimize and develop new, safer drugs.
Two renowned medical researchers, Sanford Markowitz and Mukesh K. Jain, receive $6.7 million awards from the National Institutes of Health (NIH) to advance studies on colon cancer and age-related cardiovascular risks.
Scientists developed a bioinspired adhesive material that can be controlled remotely by UV light, transporting micro-objects with high precision. The material consists of mushroom-shaped adhesive microstructures and elastic porous material, allowing for reversible control and detachment.
A recent study revealed that climate change is expected to disrupt the balance of nutrients in mountain ecosystems, potentially leading to changes in plant growth and biodiversity. The research found that decreasing elevation can serve as a surrogate indicator for climate warming, leading to increased nitrogen availability in soil.
Researchers developed novel brain-mapping techniques to identify subtle changes in skull and brain shapes, giving a greater insight into conditions. The study focused on Cavalier King Charles Spaniel breed and identified characteristics that cause painful Chiari malformation and Syringomyelia disorder.
Researchers at Stanford University and the University of Tokyo successfully transplanted functional mouse islets into diabetic mice, reversing their condition with minimal immunosuppression. The study suggests a potential approach to generate genetically matched human organs in large animals.
Healthcare professionals have high variation in judgement when assessing the same claimant for disability benefits. The use of standardised approaches to guide judgment is strongly associated with higher agreement, highlighting the need for more research and improved assessment methods.
Researchers found that myokines enhance human cognitive function, plan to use this feature to correct conditions such as autism and memory disorders without medication. They conducted comprehensive studies involving volunteers and animals, including mice, to investigate the production of myokines.
A study of 351 patients with EGFR mutant lung cancer and brain metastases found that radiation therapy followed by targeted medicines resulted in the longest overall survival, with median survival times of 46 months and 30 months respectively. The findings suggest that a more aggressive approach to treating brain metastases may be the ...
A study at Columbia University Medical Center found that a missing CRKL gene causes kidney and urinary tract defects in people with DiGeorge syndrome. The team analyzed genomic data from over 2,600 children with congenital anomalies of the kidney and urinary tract.
A Stanford-developed deep learning algorithm accurately diagnoses skin lesions as well as board-certified dermatologists, with potential to provide life-saving smartphone diagnosis. The algorithm was trained on a database of nearly 130,000 images and tested against 21 dermatologists in identifying malignant carcinomas and melanomas.
Researchers found that exposure to pollution from fires in the last few months of gestation leads to earlier birth and smaller babies. The study highlights the need for evidence-based policies to balance economic and environmental goals, especially in developing countries.
Mass drug administration programmes have significantly increased treatment for bilharzia, killing an estimated 280,000 people annually. Praziquantel MDA programmes are effective but long-term effects and resistance to the drug are largely unknown.
Two groups of jumping spiders, Habronattus and Maratus, have evolved rare color vision to see reds, yellows and oranges. They use different mechanisms, with Habronattus employing a red filter and Maratus relying on ultraviolet, blue and green sensitive cells.
Dr. Timothy Anderson received a 5-year, $4.6 million MERIT Award to study drug resistance in malaria parasites and develop effective treatment strategies. The award supports his efforts to understand the genetic determinants of resistance and apply powerful gene editing technologies.
A study found that psychological distress, including anxiety and depression, may increase the risk of death from cancer types such as bowel, prostate, and pancreatic cancer. Higher levels of distress were associated with consistently higher death rates in these groups.
A study published in The BMJ found that hormone treatment among pregnant women with subclinical hypothyroidism is associated with a lower risk of pregnancy loss, but an increased risk of preterm delivery, gestational diabetes, and pre-eclampsia. Women treated with thyroid hormone had a lower risk of pregnancy loss compared to untreated...
The researchers have developed an ultra-lightweight, highly powerful artificial muscle using rubber tubes and high-tensile fibers. It has a strength-to-weight ratio 5-10 times greater than conventional electric motors and hydraulic cylinders, making it suitable for tough robots that can handle strong external shocks and vibrations.