A new rule developed by Canadian researchers could help hundreds of thousands of women stop taking life-long blood thinners for unexplained vein blood clots. According to the HERDOO2 rule, half of women with unprovoked clots are at low risk of recurrence, allowing them to discontinue medication.
A collaborative study published in PLoS ONE found that fences with or without crossing structures can reduce roadkill by up to 54% across all species. Focusing on effective prevention methods, researchers also recommend increasing the duration and comparability of future studies to protect biodiversity.
A study published in Nature Astronomy found that blue binaries in the Kuiper Belt formed closer to the Sun and were shaped by Neptune's gravitational nudges. The research suggests a smooth and calm migration of Neptune from 20 AU to its current location at 30 AU, allowing fragile binaries to be pushed out to their current orbits.
Researchers at Carnegie Institution have synthesized pure samples of Si-III, a semiconductor with an extremely narrow band gap, narrower than diamond-like silicon crystals. This discovery may lead to unpredictable technological breakthroughs in fields like solar energy and electronics.
The study reveals that Yamnaya warriors married local Stone Age women, adopting an agrarian lifestyle and forming the Corded Ware Culture. This integration led to a rapid genetic changeover from Neolithic to Corded Ware cultures in Europe.
Researchers have created a self-healing material that can stretch up to 50 times its original size and automatically stitch itself back together within a day. The material, which uses ion-dipole interactions, could potentially be used to repair smartphones and other electronic devices.
Researchers at the University of Calgary discovered that nanoparticles can enhance or attenuate viscous fingering, a phenomenon where fluids converge in finger-shaped patterns. The study found that nanoparticle deposition rates and diffusion rates can destabilize flows, creating vortex dipoles.
A new study of ancient DNA from northwest North America finds evidence of genetic continuity spanning over 10,000 years. The research suggests that indigenous groups living today in southern Alaska and British Columbia are descendants of the first humans to inhabit the region, supporting their oral traditions.
Researchers found metreleptin treatment improved liver function and reduced fatty liver disease progression in patients with partial lipodystrophy. Patients with lower baseline leptin levels showed higher response rates to the treatment.
A new study by researchers at the University of Gothenburg found that many treatments for urinary and fecal incontinence are ineffective, with surgery being the most successful treatment option. The study analyzed thousands of research articles and found that only 37% of people treated with bulking agents achieved long-term success.
Researchers have discovered that topaz granites are extremely enriched in lithium and have a high concentration of metals such as tin and tungsten. The study's findings may impact where to look for these metals across the region, particularly in Cornwall and Devon.
Researchers have developed a new method to diagnose cancer using ultrasound and microbubbles that can identify malignant tumors with high accuracy. The technique has shown promise in distinguishing between benign and malignant breast and ovarian tumors, potentially reducing unnecessary surgeries.
A coalition led by the Mexican government has developed a bold emergency plan to rescue and protect the critically endangered vaquita porpoise. The plan includes construction of a sea pen sanctuary with up to $3 million in funding, aiming to recover a population that once numbered 600 animals.
A new depression diagnosis model suggests a staged approach from wellness to disorder could improve communication and treatment. The model proposes different stages of depression, with patients receiving guided self-care or clinical interventions depending on their stage, to address the dimensional nature of the condition.
A new study presents evidence that vitamin D deficiency is associated with increased markers of cardiovascular disease in overweight and obese children. The research found a significant link between low vitamin D levels and higher levels of atherogenic lipids, triglycerides, and non-HDL cholesterol.
Researchers found that ubiquitin-interacting motifs in USP25 determine its preferential cleavage of Lys48-linked ubiquitin chains. The study reveals a unique mechanism for substrate specificity, which could have implications for understanding protein regulation and degradation.
New research suggests that carbon dioxide concentrations will head towards values not seen since the Triassic period due to human activities. The study finds that if humanity fails to tackle rising CO2, by AD 2250 CO2 levels could reach 2000 ppm, potentially unprecedented in 420 million years.
The US Air Force and Walt Disney Company have been recognized for their pioneering use of operations research (O.R.) to improve decision-making processes. The organizations have effectively integrated O.R. into their daily operations, resulting in enhanced efficiency, effectiveness, and innovation.
Scientists identify a specific placental sugar that binds tightly to the Zika envelope protein, allowing it to cross the placenta and cause birth defects. Researchers are developing a strategy to block this interaction using a nanoparticle coated in the same sugar.
North Carolina State University researchers have developed elastic, touch-sensitive fibers that can detect strain, twisting, and touch. The fibers use liquid metal alloy to store electric charge, enabling different electronic signals based on touch location.
A new Yale-led study reveals a connection between drought exposure and adverse human health among older adults in the US. Researchers found that severe drought conditions increase the risk of mortality among adults 65 or over, as well as cardiovascular disease risk, particularly in areas where droughts are rare.
Researchers found that common cancer drugs increase blood sugar levels, which can damage healthy cells and make them more vulnerable to chemotherapy. Fasting or glucose reduction reversed this increase in toxicity in mice.
Research suggests that modifying diets by a few grams per day can significantly reduce groundwater use, cut greenhouses gases, and improve human health. Small and medium farms are essential to sustain global food supply, with estimates suggesting a 70% increase in food availability needed by 2050.
Fast-learning bumblebees collect fewer resources and have shorter foraging careers, according to a new U of G study. The researchers found that the energy demands of intelligence may eat up limited resources, leaving smart bees with less energy.
Researchers have discovered biological evidence of atypical chronic fatigue syndrome, a complex and debilitating disease. The study found lower levels of certain immune molecules in individuals with atypical ME/CFS compared to those with classical symptoms.
Researchers found that a large number of CMV's genes help it evade the immune system by destroying proteins produced during infection. This discovery could lead to novel treatments or a cure for this virus.
A study published in JAMA found that early low-dose hydrocortisone treatment in very preterm infants did not result in adverse effects on neurodevelopmental outcomes at 2 years of age. The researchers analyzed data from the PREMILOC trial and found no significant differences in patients with or without neurodevelopmental impairment.
Research found a heightened risk of abnormal growths in the colon and rectum among women who used antibiotics for extended periods during their 20s-50s. Long-term antibiotic use was associated with a 36% increased risk of colorectal adenomas, which may precede bowel cancer.
Engineers at MIT have developed a microfluidic technique to capture and count circulating plasma cells from small samples of blood, potentially providing a less painful test for multiple myeloma. The device uses conventional blood draws and can detect the ratio of different antibodies produced by cancerous and healthy cells.
Researchers developed a continuous monitoring system to detect potential machine faults through sensor analysis. The system can identify subtle changes in signal patterns, allowing for early warning of damage or mechanical wear.
A Korean research team develops high-performance silver nanowires with strong adhesion using flash light-material interactions. The Ag NWs demonstrate six times higher conductivity than pristine NWs, and their adhesion to substrates is enhanced by 310%.
Researchers found that LSD decreases activity in the amygdala, a region related to processing negative emotions like fear. This 'de-frightening' effect may contribute to positive therapeutic outcomes.
A study by researchers at McMaster University found that low-dose penicillin in early life can induce long-term behavioral changes, including elevated aggression and lower anxiety levels. Introducing beneficial bacteria may help prevent these effects.
A new study by NIOO-KNAW ecologist Bart Grutters suggests that exotic water plants can be a valuable asset in aquatic ecosystems, offering similar benefits to indigenous species. The research found that properties such as chemical defences and stem rigidity should be considered when evaluating the impact of exotic species.
Osaka University researchers used sharp, ultra-short laser pulses to generate charged particles, achieving beams with higher energy and more precise control. The study challenged conventional models, finding that lower-intensity laser light can produce high-energy charged particles.
Researchers found two new mutations on the PPX2 gene responsible for PPO-inhibiting herbicide resistance in Palmer amaranth. The glycine 210 deletion and R98 region mutations confer resistance to multiple herbicides, with some plants carrying both mutations.
Researchers have developed a new experimental technique to take 3D images of molecules in action, combining two technologies to probe the structure and behavior of molecules. This tool enables experiments with larger molecules that were previously impossible, allowing for better understanding of quantum mechanics in complex systems.
The UPV/EHU's Advanced Control Group has successfully developed a sliding mode controller to maintain maximum power point of solar panels despite changes in irradiation and load. This control system offers improved efficiency compared to traditional algorithms, which cause oscillating working points and diminish efficiency.
Scientists are working on tweaking T-cell therapy for leukemia to apply to solid tumors like ovarian cancer. The researchers identified proteins overproduced by ovarian cancer cells and found that engineered T cells can kill both human and mouse ovarian cancer cells in the lab.
The American Geriatrics Society and National Highway Traffic Safety Administration launched a public information campaign to help older adults and caregivers access resources for safely navigating the open road. The campaign provides actionable safe driving tips, conversation advice, and transportation alternatives to promote mobility ...
A laboratory study found that a diet rich in folic acid and vitamins can impair the cognitive skills of offspring mice. The findings suggest that epigenetic changes in the paternal genome can be transferred to the next generation, potentially affecting human health.
Researchers at ETH Zurich have solved the mystery of producing nanoplatelets, which are flat, uniform crystals with striking colors. The team developed a theoretical model and experimentally confirmed its predictions, paving the way for alternative materials to quantum dots in displays and solar cells.
Researchers have found a way to deliver cancer drugs to hypoxic regions of solid tumors, making them more susceptible to treatment. The new delivery system, using liposomes to carry prodrugs, has shown promising results in treating non-small cell lung cancer.
Researchers found that people who are aware of a product's price tend to evaluate the experience more critically, resulting in decreased satisfaction. For consumers, avoiding price focus can prolong enjoyment, while for marketers, separating price from experience may prevent consumer burnout and increase purchasing loyalty.
A new hand-held EEG device has been shown to accurately rule out brain bleeding in patients with head injuries. The device, approved by the FDA in 2016, can quickly assess electrical activity in the brain to determine if a patient needs further evaluation and treatment.
A recent study found that psychiatric disorders do not increase the risk of Alzheimer's disease, contrary to previous assumptions. However, the study suggests that some psychiatric disorders may be prodromal symptoms of Alzheimer's disease, highlighting the importance of proper differential diagnostics.
Researchers at the University of East Anglia have developed a novel mass spectrometry method to study iron-sulfur cluster proteins, which are crucial for various biological processes. The study successfully detects all reaction components simultaneously, providing detailed insights into their conversion process.
Researchers found that inhaled corticosteroid use is associated with a higher body mass index (BMI) and an increased prevalence of the metabolic syndrome in women. Corticosteroid users had a 1.4-fold elevated likelihood of having the metabolic syndrome, with nearly a point higher BMI.
The US Air Force Academy has been awarded the 2017 UPS George D. Smith Prize for its effective preparation of students to become frontline analytics practitioners in the Air Force. The academy's O.R. program provides cadets with access to real-world data and problem-solving opportunities through partnerships with top organizations.
A novel coronavirus found in a Ugandan bat is 87% identical to the one causing MERS, but lacks key proteins allowing it to infect humans. Researchers say the virus is unlikely to spread to humans, despite its similarities.
Researchers have observed and interpreted a cosmic phenomenon resulting from the acceleration of gas clouds by black holes and reacceleration by shock waves. The study reveals the connection between double acceleration and radio emission in galaxy clusters.
A recent study found that high-calorie diets cause similar levels of bone loss in mice regardless of fat content. Glucocorticoid signaling in the skeleton plays a crucial role in diet-induced metabolic disturbances. Disrupting this signaling pathway may protect against obesity and related health issues.
Low birth weight and high birth weight are associated with the severity of liver disease in children, increasing their risk for NAFLD. Children born with low-birth weight are more likely to develop severe scarring of the liver, while those with high-birth weight are at greater risk for the hepatitis form of fatty liver disease.
Research tracked over 3,000 women and found that small weight gains within the healthy BMI range doubled their risk of gestational diabetes compared to those with stable weights. Women who gained more than 2.5% of their body weight each year had almost triple the risk of developing gestational diabetes.
Researchers found that fluted Clovis points have a thin groove that acts as a shock absorber, increasing point robustness and ability to withstand physical stress. The technique, absent in Northeast Asia, allowed early colonizers to travel long distances with confidence.
A new study by University of Illinois experts finds that experienced auditors can detect fraud more accurately when prompted to look for signs of guilt in the CEO's voice. The researchers compiled judgments from 31 veteran auditors, who improved their accuracy rate from 43% to 70% with the cue. This suggests that even seasoned auditors...
A phase II trial found that adding rice bran to the diet of colorectal cancer survivors increased microbiome richness and diversity. The study also showed reduced cell growth in treated cells when participants consumed high amounts of rice bran.
A study found that individuals with obesity who participated in a structured weight loss program reported fewer hours missed from work after six months. On average, participants worked 6.4 hours more than expected, while their overall work performance did not change significantly.
Alpha-tin, commonly called gray tin, shows a novel electronic phase under strain, exhibiting massless Dirac fermions in three dimensions. This discovery holds promise for novel physics and potential applications in technology, including ultrafast electronic devices and spintronic devices.
Researchers at Case Western Reserve University have identified a new target for improving cardiac output in heart failure patients by modifying a specific protein. Modifying the serine 302 amino acid on myosin binding protein-C (MyBP-C) can significantly enhance cardiac function, providing a promising therapeutic approach.