A randomized clinical trial found that ivabradine did not improve outcomes in patients with heart failure with preserved ejection fraction. Elevated heart rate is a predictive factor of worse outcomes in these patients, contradicting previous research that suggested benefits for heart failure with reduced ejection fraction.
A study of over 20,000 heart failure patients found that unemployment is associated with a 50% increased risk of death and 12% higher risk of rehospitalization for heart failure. Employment status was also linked to morbidity and mortality in younger patients.
Ten patients at Penn Medicine have been cured of Hepatitis C following kidney transplants from HCV-infected donors. The study demonstrates the potential for increasing organ supply and may open up new transplant options for hundreds more patients.
A meta-analysis of prospective studies reveals that individuals with non-O blood groups (A, B, AB) are at a higher risk of heart attacks and overall cardiovascular mortality. The study found a 9% increased risk of coronary events and cardiovascular mortality in non-O blood group carriers compared to O blood group carriers.
A new classification system identifies distinct patient profiles with varying outcomes in acute heart failure hospitalizations. The study provides valuable insights for early triage and treatment decisions.