A team of international archaeologists has re-examined a c. 8,500-year-old by-product from metal smelting and found conclusive evidence of an incidental copper firing event. The discovery provides new insights into the origins of metallurgy in the Near East.
Research in mice suggests that eating at abnormal times can weaken the daytime potency of an enzyme protecting against UV radiation, leading to increased risk of sunburn and long-term effects like skin cancer. A normal eating schedule may provide better protection from UV rays during the day.
A new study reveals that subsea permafrost in the East Siberian Arctic Shelf (ESAS) degrades at a rate of 18 cm/year, exceeding previous estimates. This suggests that massive methane emissions into the atmosphere may occur due to the destruction of hydrates, contradicting IPCC climate model predictions.
Researchers at EPFL have developed a substrate-specific method to detect electron transfer in photovoltaic devices. The new approach uses deep-ultraviolet continuum pulses to probe the excitonic transitions of transition-metal oxide substrates, providing a route to studying solid-state-sensitized solar cells.
The school has awarded over $3.5 million in grants since its opening in 2014, with the latest grant targeting breast cancer treatment. Dr. Kamaljit Kaur's research aims to develop peptides that target specific receptors on cancer cells, reducing toxic side effects and improving patient survival.
Researchers will investigate regulatory mechanisms and biomarkers of healthy aging, aiming to understand why the immune system weakens with age. The study may lead to new treatments for age-related health issues, such as increased vulnerability to infections and cancers.
Researchers developed a new inlet design for Hall thrusters that significantly increases thrust by creating a vortex in the discharge channel. The design improvement resulted in higher gas density and uniformity, leading to improved performance and increased specific impulse of up to 53.5%.
Researchers in the Netherlands have created efficient green solar panels using soft imprint lithography, which scatter green light and maintain a 10% power reduction. The technology has potential to widen solar panel use as an architectural design element.
A meta-analysis of randomized-clinical trials found that full-dose bivalirudin infusion post-PCI for four hours is associated with improved net adverse clinical events and all-cause mortality. Bivalirudin exhibits a lower risk of bleeding compared to unfractionated heparin, but also increases the risk of acute stent thrombosis.
A new study reveals that thriving in elite sports requires a combination of internal and external factors, including optimism, focus, and high motivation. The research found that athletes who are highly motivated, develop holistically, and have a sense of belonging tend to thrive at the highest level.
Researchers at the University of Queensland have discovered that adult brains can produce new cells in the amygdala, a region important for processing emotional memories. This finding has significant implications for understanding the brain's ability to adapt and regenerate.
Typhoon Banyan's eye became visible again in satellite imagery from NASA-NOAA's Suomi NPP satellite, showing a tight concentration of strong thunderstorms around its center. The storm is expected to become a strong extra-tropical storm in the open waters of the Northwestern Pacific Ocean by August 17.
The Biophysical Society has announced its 2018 Society Fellows, recognizing distinguished members who have made significant contributions to the field of biophysics. The 2018 Fellows include Patricia Bassereau, James Bowie, Astrid Graslund, Roderick MacKinnon, and others.
University of Nevada, Reno researchers are developing mosquitoes that can detect and avoid human odors, potentially breaking the transmission cycle of mosquito-borne diseases. The goal is to create genetically modified mosquitoes that feed on other animals, reducing resistance development.
The new data resource center will accelerate novel treatments for childhood tumors by making genetic sequences available on the cloud. Researchers expect to identify beneficial mutations that allow some children to survive longer than others.
A University of Kansas researcher found that well owners in Kansas use more water during droughts due to their ability to irrigate crops. Unlike non-well owners, who cut back on water usage, well owners tap into the aquifer to sustain crops during dry years.
Researchers sequenced and compared apple genomes to reveal a two-way journey for domesticated apples along the Silk Road. The study pinpointed the origin of domesticated apples in Kazakhstan and discovered that they hybridized with local wild apples, yielding modern dessert apples.
A recent study found that gaining distribution in small retail formats, such as Save-A-Lot and Aldi, can lead to significantly higher sales increases compared to larger assortment stores. The study, published in Marketing Science, analyzed data from Systembolaget, a Swedish state-owned monopoly, and found that a 10% widening in retail ...
Clinical studies supporting FDA approval of high-risk medical device modifications were found to be methodologically poor, with many lacking randomization and blinding.
Research finds that human activities such as urbanization and forest fragmentation alter fruit bat habitats, increasing the risk of Hendra virus transmission to humans. The study highlights the importance of preserving ecosystem integrity and habitat suitability to mitigate this risk.
Researchers identified pheromone receptors in a primitive moth species that also respond to plant volatiles, suggesting an evolutionary link between sex pheromones and plant odor detection.
A new study by NYU's Steinhardt School of Culture, Education, and Human Development found that children whose parents provide them with learning materials and engage in meaningful conversations develop early cognitive skills that cascade into later academic success. The study tracked the influence of early home learning environments on...
Researchers discovered a potential broad-spectrum antiviral by inhibiting the EZH2/1 complex, which suppressed HSV infection and reactivation in mice. The treatment also showed promise against other viruses, including human cytomegalovirus, adenovirus, and Zika virus.
Biomedical engineers have grown miniature human blood vessels exhibiting symptoms of Hutchinson-Gilford Progeria Syndrome, an extremely rare genetic disease. The technology will help doctors screen potential therapeutics more rapidly, with the goal of creating a personalized screening platform.
Researchers at Caltech simulated earthquakes in a lab to measure dynamic friction and its impact on seismic events. They found that slip velocity is the key factor in dynamic friction, contradicting previous assumptions.
Researchers project a significant increase in harmful algal blooms in US freshwater reservoirs and lakes due to climate change. The study predicts that the biggest impact will be felt by recreation areas in the Southeast, with more rural regions also affected.
Researchers developed a nanosensor to detect herbicides and their target enzymes, crucial for environmental monitoring. The Atomic Force Microscope cantilever proved suitable for precise detection of environmental contaminants.
Researchers have developed a more precise way of diagnosing suicide risk by identifying biomarkers in blood that change in concert with changes in suicidal thoughts. A refined set of biomarkers applies universally to predict risk of suicide among both male and female patients, while others are specific to diagnoses and genders.
The University of Nevada, Reno is starting a drilling campaign to test its geothermal exploration strategies in the Great Basin region. The project aims to identify new, economically viable geothermal systems and reduce risks for commercial electricity production.
A study using liquid biopsies found distinct genomic profiles in 99.7% of patients with CUP, harboring potentially targetable alterations. These findings suggest that liquid biopsies can guide treatment response in this patient population.
A new species of damselfly, Mesosticta davidattenboroughi, has been discovered in mid-Cretaceous Burmese amber and named after Sir David Attenborough. The fossil is extremely well-preserved, showing a complete set of wings, and provides new insights into the past appearance of a rare group of damselflies.
Research by University of Kansas sociologist Ruth Stamper finds that local food systems in Kansas and Missouri help disparate groups build relationships, bridging moral orders and environmental ideologies. Through shared sustainable farming knowledge and education, farmers from diverse backgrounds find common ground.
Researchers found that plants growing in dry climates have higher concentrations of leaf wax, a natural protective barrier. The team bred winter wheat cultivars with increased wax production, which enabled them to tolerate drought and produce high yields.
A meta-analysis published in PLOS Medicine found that gabapentinoids have no significant improvement in pain relief for chronic low back pain, and may even worsen symptoms. The study analyzed findings from 8 randomized controlled trials and identified significant risks of adverse events such as dizziness and visual disturbances.
Muller Fabbri's research focuses on targeting immune cells contributing to disease progression in neuroblastoma. He aims to identify new molecular targets to prevent and overcome cancer resistance to treatment.
The PCORI Board approved $10 million for two studies to compare strategies for reducing unsafe opioid prescribing and improving pain management. The studies will focus on Medicaid payer strategies and healthcare provider interventions to expand non-opioid approaches, with the goal of providing evidence-based information to improve pati...
Scientists at the John Innes Centre have produced a new vaccine against poliovirus using virus-like particles grown in plants. The vaccine uses a method that employs virus-like particles (VLPs) - non-pathogenic mimics of poliovirus which are grown in plants.
Researchers discovered that targeting arginase 2, an enzyme involved in nitrogen metabolism, can curb the growth of pancreatic tumors, especially in obese individuals. The study suggests a novel approach to treating this deadly cancer, with potential for improved survival rates and therapeutic windows.
Researchers found that compounds from the desert creosote bush exhibit powerful anti-parasitic effects, particularly against Giardia and Naegleria fowleri. The study offers a promising lead for developing new antimicrobial agents to combat deadly parasitic infections.
Researchers developed a genome sequencing method that can detect clinically relevant mutations using just 5 circulating tumor cells. The technique, known as long fragment read (LFR), is more comprehensive than gene panels and can analyze the entire genomic content of small numbers of cells.
A new study finds that same-sex couples do not influence their adopted children's gender identity development, with typical behavior emerging from early childhood. The research suggests that family structure has little impact on gender conformity or nonconformity.
A study by the University of Kent found no correlation between social influence and personal autonomy, suggesting that increased power actually diminishes feelings of freedom. The researchers also discovered a lack of personal power correlates with a lack of social power.
Research published by Chapman University found that transgender students in California are at a higher risk of substance use compared to their non-transgender peers. The study showed that transgender students were more than two times more likely to engage in substance use throughout their lifetimes.
University of Groningen scientists have developed a graphene-based device that can inject and detect electron spins with unprecedented efficiency, increasing the spin signal by a hundredfold. The discovery has significant implications for the development of spin transistors and spin-based logic.
Researchers propose that environmental factors play a significant role in shaping gender-specific traits, rather than solely genetic inheritance. This idea challenges the long-held assumption that biological sex directly influences behavior.
A new study shows significant improvement in sexual and urinary function as well as quality of life for hypogonadal men undergoing long-term testosterone replacement therapy. Testosterone therapy is found to increase bladder emptying, improve erectile/sexual health and overall quality of life.
A new analysis of care needs in England from 1991 and 2011 reveals an increase in years spent with substantial care needs for older adults. By 2025, an estimated 191000 more people will require medium dependency care, leading to a need for an additional 71000 care home places.
Researchers discovered that intestinal cells use a strategy to increase protein production within minutes of food entering the intestines, enabling fast and efficient processing. This approach has potential medical implications for diseases such as colitis, Crohn's disease, and bowel cancer.
Researchers have made a groundbreaking discovery, finding that an amino acid called methionine may play a crucial role in the development of schizophrenia. Excess methionine during pregnancy has been shown to alter fetal brain development, leading to changes in gene expression and potentially life-long consequences.
The discovery of two new beetle genera and four new species from the Australopacific Region highlights the diversity of saprinine hister beetles. The newly described insects feature interesting morphologies and ecologies, with some species dependent on ants or termites for survival.
Researchers designed a therapeutic fusion protein that triggers increased S1P receptor activity, recovering blood vessel health in mice with various vascular diseases. The combination of ApoM-Fc and S1P reduced blood pressure and mitigated tissue damage.
A retrospective study of nearly 1,100 patients with severe TBI found that ICP monitoring was associated with a significant decrease in mortality rates, but no improvement in favorable outcomes. The study also showed that ICP monitoring was linked to more aggressive therapy.
Researchers are developing a networked airborne computing platform to facilitate the use of unmanned aerial systems (UAVs) for civilian applications. The platform will enable real-time data sharing and faster mission response times, increasing safety and efficiency.
Researchers have discovered how glutamine controls gene programs in cells, revealing a new mechanism of differentiation and gene regulation. This finding has significant implications for understanding developmental biology, the immune response, and cancer dysregulation.
Dr. Dasgupta is recognized for his work improving public health globally, including a new method for measuring blood in dry blood spot analysis and an implantable shunt flow monitoring system for hydrocephalus patients. He has also made significant contributions to environmental and astrochemical research.
University at Buffalo researchers have developed a method to compare human and rodent cells, providing insight into gene expression patterns conserved across species. This approach identified a new gene involved in myelin repair that may become a therapeutic target for MS patients.
Researchers found that wood frogs with pesticide tolerance are more susceptible to a deadly virus and a parasitic worm, while those far from agriculture have reduced susceptibility. This study highlights the complexity of pesticide-parasite interactions and the need to consider multiple stressors in environmental conservation.
A recent study found that while marijuana use amongst youth has remained relatively unchanged, admissions to substance abuse treatment facilities have increased. Researchers attribute this rise to a heightened perception of high-risk behavior among young people, particularly as states legalize marijuana.
Astronomers have discovered a unique lensing system that provides the best view yet of blobs of hot gas streaming from supermassive black holes. The discovery allows scientists to see these clumps closer to the central engine of the black hole and in greater detail than before.
A new study by Texas Tech University Health Sciences Center El Paso researchers explores the impact of prior West Nile virus exposure on Zika infection. The team collected blood samples from 500 individuals and tested for West Nile antibodies to determine whether previous exposure could inhibit or enhance Zika infection severity.
The Patient-Centered Outcomes Research Institute's Board approved $115 million to fund 20 comparative clinical effectiveness research (CER) studies on various conditions. These studies will investigate the most effective approaches to care planning, opioid prescribing, palliative care and more.
Children's Hospital of Philadelphia will lead a collaborative effort to discover causes of childhood cancer and structural birth defects using big data. A centralized database and discovery portal will be created to share well-curated clinical and genetic sequence data from dozens of cohorts, comprising thousands of patients.
A study by FAU researchers found that men tend to be more aggressive than women in competitive situations, while team players exhibit less aggression. Cortisol levels also decreased in participants exhibiting aggressive behavior.
Scientists have tracked a solar storm using data from 10 NASA and ESA spacecraft, shedding light on how coronal mass ejections (CMEs) move through space. The study provides key information for understanding space weather effects on the solar system.
A three-year NSF grant will fund a comprehensive assessment of how invasive non-native grasses alter fire patterns and carbon storage across the contiguous US. The researchers aim to quantify changes in carbon stocks associated with invasion and fire, providing new insights on managing fire-prone invasive grasses.
Researchers measured the effect of low-level mercury concentrations on microalga gene expression, revealing widespread deregulation of genes involved in various processes. This study provides insight into the environmental and public health implications of mercury's entry into the food chain.
EZH2/1 inhibitors, used in cancer clinical trials, have activity against a variety of viruses, including HSV. These compounds suppress viral gene expression and induce antiviral pathways.
A new study found that patients who responded to ketamine treatment had increased early morning activity and lower evening activity levels. Altered circadian timekeeping systems may mediate ketamine's effects on mood.
A recent study published in JAMA found that many studies supporting changes to high-risk medical devices are poorly designed and lack rigor. The researchers analyzed 83 supplement approvals for these devices and found similar problems with data quality and analysis procedures as seen in premarket approval studies.
Tropical Storm Gert strengthened into a hurricane, generating intense rainfall and dangerous surf along the US East coast. The storm's eastern side showed the most intense rainfall rates, with some areas reaching over 3.5 inches per hour.
Researchers have developed a new learning algorithm that mimics the human brain's ability to forget unimportant memories, enabling computers to learn and forget in a proper way. This technology, called organismoids, uses quantum materials to create devices that can adapt and change their behavior over time.
Researchers found that high levels of silicon concentrations decrease insect growth and root consumption by up to 71%. Silicon helps plants build phytoliths, making them less digestible to insects, and triggering an immune system response. This natural defense mechanism could provide a sustainable solution for crop protection.
New research from Iowa State University found that police officers' accuracy in detecting concealed weapons or threats is only slightly better than chance. The study's findings highlight the need for better training and research-based approaches to threat detection.
Scientists confirm weathering of rocks is key to planet's recovery from extreme temperatures, enabling life to thrive for over 4 billion years. However, rapid global warming poses a threat to this recovery process, highlighting the need for urgent action.
A study found that patient empowerment tools can improve hand hygiene compliance among healthcare providers. However, only half of physicians support patients reminding them to perform hand hygiene, citing concerns about the patient-doctor relationship.
The study reveals that bacterial defense mechanisms are highly organized in response to nutrient stress, but become disorganized when faced with antibiotics. The researchers used experimental and computational methods to understand the workings of the bacterial defense system.
A new machine learning program developed by researchers at Case Western Reserve University appears to outperform other methods for diagnosing Alzheimer's disease before symptoms begin. The program integrates various indicators of the disease, including mild cognitive impairment, to predict who has Alzheimer's and those with mild cognit...
A new study found that women with early-stage breast cancer are more likely to consider double mastectomy due to their decision-making habits and values. Researchers surveyed 2,362 women and discovered that those who were worried about making a bad decision and wanted to make their own choices were more likely to consider the aggressiv...
North Carolina State University engineers have developed a hands-free method for filling complex microchannels with liquid metal using vacuum, eliminating the need for outlets and reducing defects. This approach enables broader use of liquid metals in electronic and microfluidic applications.
A University of Texas at Arlington civil engineer will model large-diameter water transmission pipes' behavior in different types of soils to establish modeling standards. The research aims to improve the reliability and economics of large diameter pipelines, ensuring a long-lasting and sustainable way of building drinking water infras...
PCORI's Board of Governors approved nearly $74 million for seven studies on palliative care. The projects will compare different strategies to deliver care and examine their impact on quality of life, hospitalizations, and caregiver burden.
A new study by Georgia Institute of Technology researchers has found that a widespread biological concept affecting cancer research could be incorrect up to two-thirds of the time. The study's findings suggest that targeting proteins based on messenger RNA levels may not be optimal, potentially leading to drug targeting errors.
A high-intensity exercise program combined with a diet plan resulted in improved blood glucose levels among adults with type 2 diabetes. The study found that 73.5% of lifestyle participants required fewer glucose-lowering medications, compared to 26.4% in the standard care group.
Researchers have discovered a critical role for type III interferon signaling in controlling Yellow Fever Virus (YFV) infection, particularly in preventing viral brain invasion and maintaining blood-brain barrier integrity. This finding provides new insights into the complex mechanisms regulating YFV infection.
A randomized controlled trial found that a brief behavioral treatment delivered by community lay workers significantly reduced psychological distress in women exposed to gender-based violence. The study tested the effectiveness of Problem Management Plus, a WHO-developed intervention, and showed promising results with a moderate effect...
Researchers have identified a gene, H2-Ob, that enables mice to resist persistent viral infections by producing specific antibodies. This gene is part of the MHC locus and acts as a negative regulator of the immune response, keeping chronic infections in check.
Researchers found that ECT had no specific anti-insomnia effect on older patients with depression. In fact, their insomnia problems persisted despite treatment improvements in non-insomnia symptoms. The study suggests that ECT may not be a reliable option for addressing sleep issues in this population.
Researchers developed a novel method to identify neural structures associated with impaired auditory word comprehension after stroke. The study mapped white matter connections beyond the damaged area, revealing crucial networks involved in speech comprehension and proposing targeted therapy approaches.
Scientists at the University of Oxford have developed a new method to 3D-print laboratory-grown cells into high-resolution tissue constructs. The approach improves cell survival rates and enables the fabrication of patterned cellular constructs that mimic natural tissues.
A new study in The American Journal of Geriatric Psychiatry found that middle-aged and older adults can successfully use a smartphone-based intervention to self-manage their serious mental illness. The app takes patients through 10 sessions over three months, covering topics such as stress vulnerability and medication adherence.
Research examines alternative reasons for climate change denial in Louisiana, highlighting economic and cultural influences. Despite high rates of denial, parish residents show environmental awareness, suggesting a focus on local issues like coastal erosion.
A new study reveals that beets can produce a pigment with high antioxidant properties, boosting crop nutrition and resistance to disease. The researchers successfully engineered plants to produce this pigment, which also showed promise in controlling gray mold in crops.
Researchers developed laser-driven plasma acceleration using low-energy, ultrashort mid-infrared laser pulses, producing relativistic electron beams. The team's findings demonstrate the potential of long-wavelength femtosecond lasers for compact and high-repetition-rate accelerators.
Researchers created a device using graphene and boron nitride, achieving unprecedented spin transport efficiency at room temperature. The device showed significant improvements in spin polarization and detection, opening up possibilities for applications such as spin-based logic and transistors.
The University of Bristol team has developed a 3D-printed acoustic levitator, allowing users to levitate liquids and insects at home. This technique has the potential to improve diagnosis in blood tests and support innovative processes in pharmaceuticals and biology.
The Biophysical Society has announced its 2018 award recipients, honoring outstanding contributions to the field of biophysics. The winners include Jue Chen, Wonhwa Cho, Bianxiao Cui, Taekjip Ha, Leslie Loew, Carrie Partch, Madeline Shea, and James Spudich for their innovative research and advancements in biophysics.
The study examined three types of distracting elements: sensorimotor, cognitive, and emotional. Researchers found that texting led to more dangerous driving, while a 'sixth sense' protected drivers from emotional upset or absent-mindedness.
Researchers found that only half of Accelerated Approval post-approval studies were completed within three years, and the characteristics did not differ much from pre-approval studies. The proportion of randomized or blinded trials was also similar.
Researchers found immigrant detention centers function like jails, with inmates required to wear orange jumpsuits and color-coded by threat level. The centers are often built in remote locations, making it difficult for detainees to communicate with families or access legal assistance.
A NASA-led CubeSat mission, CUVE, is designed to investigate the nature of a mysterious absorber in Venus' uppermost cloud layer. The mission will utilize ultraviolet-sensitive instruments and a novel carbon-nanotube light-gathering mirror to gather data.
A study by Justin Knoll found that individuals with a high tolerance for incivility are more likely to engage in online behaviors such as commenting on news stories, participating in discussions, and donating to candidates. In contrast, activities like signing petitions and circulating content were not affected.
A study published in JAMA found that drugs granted accelerated FDA approval often relied on nonrandomized studies and surrogate measures to confirm efficacy, with many lacking statistically detectable differences in design features between pre- and post-approval trials. Despite positive results from postmarketing studies, clinical bene...
Researchers at University of Cambridge and Natural History Museum analyze 450 anatomical characteristics to place Chilesaurus in dinosaur family tree. The study reveals Chilesaurus fills a large gap between two major dinosaur groups, with implications for understanding the origins of Ornithischia.
A team of UK researchers investigated the impact of water droplets on spherical soft surfaces, revealing that surface curvature enhances retraction of impacted drops. The effects of impact parameters, including diameter ratios and polymer elastic modulus, were also studied.
Research reveals distinct molecular patterns in premature infants' cerebellum, indicating a cellular response to interrupted development. The findings may offer insights into long-term complications of pre-term birth and potential interventions to improve outcomes.
A new chewing gum-based diagnostic test can detect inflammation in the oral cavity within five minutes, allowing for early diagnosis and treatment. The test uses bittering agents to identify inflammatory conditions, which can help prevent serious complications such as bone loss.
A new AI system developed by MIT researchers reduces online video rebuffering and improves quality, adapting to different network conditions. The system achieves higher-quality streaming with less rebuffering than existing approaches.