Researchers from Brigham and Women's Hospital are set to present groundbreaking findings on cardiovascular treatment at the ESC Congress 2017. These studies, including CANTOS and RE-DUAL PCI, will provide new insights into the effectiveness of anti-inflammatory therapy and dual antithrombotic therapy in patients with atrial fibrillation.
A study of Russian cosmonauts found significant changes in their bodies due to spaceflight, affecting all major cell types and organs. The research revealed that the human body lacks mechanisms to rapidly adapt to such extreme changes, leading to widespread physiological responses.
A new prediction tool has been developed to identify elderly patients at greatest risk of acute myocardial infarction during Asian dust storms. The tool, based on a simple scoring system, takes into account various pre-existing conditions and can help prevent AMI in high-risk patients.
Climate change creates extreme conditions that impact railway bridge maintenance, requiring new solutions to mitigate track deterioration and reduce carbon emissions. The study evaluates the effectiveness of eight mitigation measures, recommending elastic rail pads, soft baseplates, and under ballast mats for short-span bridges.
Researchers at Brigham Young University have developed a miniaturized mass spectrometer capable of analyzing chemicals with high sensitivity. This portable device has significant implications for applications such as detecting chemical weapons, explosives in airports, and forensic investigations.
A study by University of Warwick finds a previously overlooked section of gene fusion FGFR3-TACC3 worsens cancer cells. Preventing cell signalling from this fusion may not be effective in cancer treatment research.
A study by Michigan State University found that parents and siblings can improve their ability to communicate with special needs children using an online training program. The training provides interactive strategies for offering communication opportunities, commenting on activities, and waiting for responses. The researchers tested th...
Peter Vitiello receives NIH grant to investigate oxygen-sensitive molecules influencing lung growth in premature infants. The research aims to reduce the burden of lasting lung disease, which can have life-long effects.
Researchers at UNC School of Medicine have discovered a damaging cascade of events inside brain cells that contribute to Alzheimer's disease. The study shows that amyloid beta protein can trigger an inflammatory response in immune cells, leading to the formation of bead-like structures filled with abnormal tau protein.
A new study found that HPV vaccination rates are significantly lower among childhood cancer survivors compared to the general population. Most participants lacked a healthcare provider's recommendation, highlighting the need for increased communication and awareness about HPV vaccination.
A study found that inattentiveness is linked to worse academic performance up to 10 years later, even when accounting for intellectual ability. Inattentiveness can have significant adverse effects on the academic performance of children with and without ADHD.
A new species of crab with star-shaped tubercles has been discovered in Taiwan and the Philippines. The Pariphiculus stellatus crab's carapace and chelipeds feature pointy protrusions that change with age, giving it a unique appearance.
Researchers at UMass Amherst have characterized the functional dance of a protein-folding chaperone's interdomain linker. The study used computational techniques to simulate the movement of the linker and revealed its role in facilitating proper function, including binding sites for potential therapeutic targets.
A study found that at least 30-45% of elite athletes admitted to using banned doping substances or methods in the previous year. Biological tests only detected doping in 1-3% of competitors, suggesting a higher true rate of doping.
Researchers at IBS and KAIST found that YAP/TAZ promotes cytoskeleton remodeling and junction formation in endothelial cells, essential for normal as well as pathological angiogenesis. Overexpression of YAP/TAZ leads to excessive blood vessel growth, while removal results in vision impairment and internal bleeding.
The CAPTAF trial found that ablation of atrial fibrillation significantly improved quality of life and general health compared to antiarrhythmic drug therapy. Ablation was also shown to reduce symptoms and improve quality of life in patients with paroxysmal and persistent AF.
A study by Tufts University researchers found that Congress has no historical justification for preempting state and local sugar-sweetened beverage taxes. The authors argue that such preemption undermines local control and challenges the financial stability of local governments.
Scientists recommend reducing disease impacts on honeybees by limiting colony mixing and supporting natural bee behaviors. This approach could help reduce parasite transmission and promote disease resistance among the bees.
A new study found that at least 30-45% of athletes surveyed at top events acknowledged using banned doping techniques, while official biological tests only detected 0.5-3.6% of cases. The study used a randomized response method to ensure anonymity and honesty from respondents.
An international study of over 135000 people found that high carbohydrate diets were associated with a 28% higher risk of death compared to low carbohydrate diets. Diets high in total fat intake were linked to a lower risk of mortality, but rates of major cardiovascular events remained similar.
Case Western Reserve researchers refine an electrical nerve-block implant to treat asthma and heart failure, focusing on blocking unwanted nerve impulses in the autonomic nervous system. The technology aims to provide a reliable, rapid, and reversible nerve block as an alternative to surgery or drugs.
A study of nearly 400 preschool children found that only one adhered to the 5-2-1-0 guidelines for a full 24-hour period. The study suggests room for improvement in dietary intake, physical activity, and screen time among young children.
Researchers found patients with psoriasis covering 10% or more of their body surface area are at almost double the risk of death. The study used an objective measure of disease severity to analyze the relationship between psoriasis severity and mortality.
IMERG data show over 30 inches of rainfall in the Houston metro area, while Harvey dropped over 40 inches in southeastern Texas. The storm is expected to produce catastrophic flooding and life-threatening conditions in parts of Texas and Louisiana.
A new study by University of Missouri researcher Brett Johnson found that while people dislike extreme speech, there is less support for outright censorship, instead advocating for clear policies promoting healthy public discourse.
Researchers have designed a new kind of antibody that targets toxic protein structures common to Alzheimer's disease, Parkinson's disease, and related conditions. The study demonstrates the effectiveness of these antibodies in removing toxic forms without triggering immune toxicity.
Researchers have identified a set of genes that help control early drought response in Brassica rapa, a popular global crop. The study sheds light on how plants respond to water stress throughout the day-night cycle, revealing potential mechanisms for improving drought resistance and fertilization efficiency.
A two-stage approach to risk-reducing mastectomy, involving initial breast reduction and
Researchers found a difference in gut bacteria between Parkinson's patients and healthy individuals even at an early stage of the disease. Certain microbes are associated with non-motor symptoms like depression. The study aims to better understand the microbiome's role in the disease.
Shaden Smith and Yang You have been awarded prestigious fellowships for their work on high-performance computing applications. They are recognized for advancing the state of the art in sparse tensor factorization algorithms and scalable machine learning algorithms.
Researchers have confirmed the significance of termolecular chemical reactions, which were previously deemed unimportant. These reactions can affect engine performance, stability, and efficiency, leading to more accurate simulations and better designs.
The Caspian Sea has been slowly evaporating over the past two decades, with water levels dropping nearly 7 centimeters per year from 1996 to 2015. This increase in evaporation is linked to rising surface air temperatures associated with climate change.
A team of entomologists has solved the mystery of a secretive fly species by studying mushrooms in Los Angeles. The females were found to lay eggs on mushroom caps, while males were discovered only after citizen scientists alerted researchers.
Researchers found evidence of sea ice at the North Pole during the last interglacial period, contradicting previous hypotheses. The study suggests that the Arctic Ocean may be free of ice in summer within 250 years if CO2 levels rise, highlighting the complexity of climate change processes.
The publication marks a significant milestone in aquatic toxicology with the release of the first generation of annotations for the fathead minnow genome. The data will enhance the utility of this species for ecotoxicology research and open up new avenues for studying its effects on ecosystems.
Researchers demonstrated a region of very deep contrast between a simulated star and its planet, achieving an 18% bandpass. This milestone is crucial for future missions like WFIRST to detect and analyze the atmospheres of giant planets.
Researchers developed DroNc-Seq, a method merging sNuc-Seq with microfluidics for parallel measurement of gene expression in complex tissues. The technique enables identification of unique expression signatures for cell types, including rare ones, and differentiation between closely related subtypes.
New study reveals that methane leaks around North Sea boreholes could be a major source of greenhouse gases, with up to 17,000 tonnes released per year. Scientists estimate that about one third of the over 11,000 wells drilled in the North Sea are leaking methane.
A 33% cutback in U.S. foreign aid for HIV treatment and prevention programs in South Africa and Côte d'Ivoire would result in devastating health and economic consequences, including over 500,000 additional cases of HIV and 1.6 million more deaths in the next decade. The study suggests that such cuts would produce proportionally greater...
Researchers found that combining CDKs' inhibitors with conventional anti-cancer drugs like cisplatin increases tumor cell death. However, treating cells with 5-FU can lead to decreased death rates and resistance. This study suggests a promising approach for developing new anti-cancer treatments.
The largest ever recorded Ichthyosaurus was a pregnant adult female, estimated to be 3-3.5m long, and is an important discovery for the field of palaeontology. The specimen, found in a museum collection, has provided valuable insights into the size range of the species and the presence of embryos.
Researchers found that PCSK9 inhibition can reverse the effects of oxidised LDL on immune activation, leading to an anti-inflammatory state that may directly influence atherosclerosis and cardiovascular disease. This new mechanism is independent of lowering LDL cholesterol.
According to an 18-year analysis, 56% of individuals aged 57-61 are likely to spend time in a nursing home, with high out-of-pocket costs for some. Lifetime spending averages $7,300, but some face expenses over $47,000.
Researchers found that ultra-low LDL cholesterol levels (below 10 mg/dL) significantly reduced cardiovascular event risk by over 40%. No adverse effects on cognition or safety endpoints were reported. The study suggests achieving low LDL cholesterol levels beyond current treatment targets may further reduce cardiovascular risk.
New research reveals young adults, particularly men, are at higher risk for heart attack and stroke due to inadequate high blood pressure awareness and management. Young adults are more likely to be obese and have lower rates of blood pressure treatment and control compared to middle-aged and older adults.
The Southern California Consortium for Technology and Innovation in Pediatrics (CTIP) has awarded $165,000 in seed grants to accelerate projects improving the safety and delivery of care to infants and children. The funded projects focus on developing innovative medical devices to address unmet needs in pediatric care.
Scientists used a giant cosmic lens to study a star-forming galaxy nearly five billion light-years away, providing clues about the origin of galactic magnetic fields. The analysis revealed a large-scale, coherent magnetic field similar to those in nearby galaxies.
Researchers at Nagoya University have created a way to manipulate the domain structure of lead zirconate titanate films, a crucial step for future electronic and electro-mechanical devices. By controlling the switching of domains, they can potentially accelerate the development of next-generation technologies.
Researchers discovered that ciliated tissues in mammals selectively recruit beneficial microbes called symbionts and clear out toxic molecules. This mechanism provides insight into the basic function of cilia surfaces and may aid development of ways to foster beneficial bacterial partners.
A Stanford University School of Medicine study found that infants' racial and ethnic identities influence the quality of medical care they receive in California's neonatal intensive care units. White infants generally received better care than those from vulnerable populations at some hospitals, while others received worse care.
A team of researchers discovered a way to treat severe inflammation from mosquito-borne diseases like Chikungunya and Ross River virus. They developed an NLRP3 inhibitor drug MCC950, which provided significant relief from inflammation and disease in infected mice.
A team of researchers at Harvard John A. Paulson School of Engineering and Applied Sciences has created a simple device that mimics the complex songs of birds, including Zebra and Bengalese finches. The study suggests that birds may have exploited the physical properties of soft materials to produce their distinctive vocalizations.
Researchers found that human neural stem cells retained an intrinsic human rate of maturation despite being placed in a traumatic rodent environment. The study's findings suggest that clinical outcome measures for future trials need to focus on long time points after grafting, as success may take time.
A 132 million-year-old plesiosaur fossil was discovered in northern Germany and identified as a new species, Lagenanectes richterae. The ancient creature had a long neck, short jaws with specialized teeth, and internal channels for electroreceptors.
A new study by the RAND Corporation found that 56% of people aged 57-61 will stay in a nursing home at least one night during their lifetime, contradicting previous estimates of 35%. The study analyzed 18 years of data and found that most people can afford nursing home care, with costs averaging $7,300 over a lifetime.
Researchers develop a new imaging technique to assess early-stage embryo quality, improving IVF outcomes. The hyperspectral imaging method measures metabolic differences in embryos, providing an objective measure of viability.
The Lehigh project aims to build bridges between optimization experts, learning theorists, and statisticians to advance machine learning. With a $1.5 million grant, the team will develop innovative educational pathways and state-of-the-art mathematical tools for data science, promoting long-term research and training activities in the ...
Researchers have made an important step toward understanding optically controlled magnetic storage devices, finding that laser light plays a key role in toggling magnetisation alignments. The study reveals the formation of a ring-shaped region around the tiny laser spot and its impact on the material's temperature distribution.
Researchers develop 'dip-and-dry' approach for selective solar absorbers, exhibiting high performance and durability. The new method yields highly efficient SSAs with contrasting optical properties for solar and thermal radiation.
A landmark trial found that a drug targeting inflammation reduced risk of major adverse cardiovascular events, including heart attacks and strokes. Participants who received the anti-inflammatory drug had a 15% lower risk of cardiovascular events compared to those on standard care.