Researchers found a wide variety of CRE species and genetic traits enabling resistance, with traits transferring easily among species. The findings suggest that CRE may be transmitting from person to person asymptomatically, highlighting the need for increased genomic surveillance.
Researchers are conducting a £1.5 million trial to test two therapies on 390 people with Osteogenesis Imperfecta, aiming to reduce fracture risk. The six-year study will track participants for five years to assess the combination of teriparatide and zoledronic acid.
Scientists at the University of Strathclyde discovered a way to create narrowband radiation with high efficiency, challenging a fundamental understanding of electromagnetic radiation. This breakthrough has significant implications for materials science and medical treatments.
A study found that epigenetic changes, not DNA mutations, drive metastasis in pancreatic cancer cells. Researchers also identified a potential therapeutic target to block tumor formation in lab-grown cancer cells.
A study by Martin-Luther-University Halle-Wittenberg found that traditional farming practices on the Yucatán Peninsula create attractive habitats for native sweat bees, improving pollination services. The researchers discovered that moderate farming with slash-and-burn practices has no direct negative impact on native bee populations.
A Vanderbilt-led study identifies a compound that can reverse the malignant reprogramming of metastatic pancreatic cancer cells. The research found that distant metastases undergo massive epigenetic changes that enable tumor formation, but these changes can be reversed with the inhibition of phosphogluconate dehydrogenase enzyme.
A new study published in Lancet Global Health found that maternal micronutrient supplements during pregnancy significantly boost child development and cognitive ability. The research also highlights the importance of a strong nurturing environment, home conditions, and parental education in shaping a child's intellectual abilities.
Researchers found that squalamine inhibits the early formation of toxic alpha-synuclein aggregates and suppresses their toxicity. The compound was tested in cell cultures, animal models, and human neuronal cells, showing promising results.
A widely used crop chemical, Sylgard 309, increases the susceptibility of honey bee larvae to a deadly virus, Black Queen Cell Virus. This finding suggests that exposure to organosilicone adjuvants negatively influences immunity in honey bee larvae, resulting in enhanced pathogenicity and mortality.
A new study from Vanderbilt University uses game theory to simulate re-identification risks and strikes an optimal balance between data sharing and privacy. The approach compares various data sharing policies in terms of risk and scientific utility, providing a more realistic estimate of the risk.
A recent study found that benzodiazepines and related drugs are associated with a 20% higher risk of stroke among persons with Alzheimer's disease. The association is stronger for ischemic strokes than hemorrhagic strokes. Cardiovascular risk factors did not explain the link.
Researchers found that feelings of jealousy increase the desire for products that will attract someone's attention. Participants who were experiencing jealousy opted to buy eye-catching products even in public, indicating a strong motivation to regain their partner's focus.
Using infrared spectroscopy and computer simulations, researchers at Ruhr-Universität Bochum discovered a magnesium atom contributes significantly to switching G-proteins on and off. This finding has implications for understanding disease mechanisms and developing targeted drugs.
The Harrington Discovery Institute has selected three 2016 partnership scholars to support groundbreaking research in Alzheimer's disease and blindness. The scholars will receive funding and expert pharmaceutical guidance to advance their discoveries into new medicines.
A study published in Social Psychological and Personality Science found that people who frequently curse are less likely to be associated with lying and deception. The research also showed that those who use more profanity tend to use language patterns related to honesty, such as using pronouns like 'I' and 'me'.
A UK study found that eating disorders are not limited to adolescence or early adulthood, affecting 3% of mid-life women. The research also identified risk factors such as childhood unhappiness, parental divorce, and sexual abuse.
A new study reveals that the head, upper arms, upper legs, and thighs are significant sources of drag for downhill skiers, with potential applications in designing better ski equipment and improving performance.
Diabetes, smoking, and physical inactivity are identified as major risk factors for cardiovascular disease among Chinese Australians. The study found a 25% higher prevalence of diabetes, a 22% higher prevalence of smoking, and a 45% higher prevalence of physical inactivity compared to non-Chinese Australians.
The Dalian Coherent Light Source (DCLS) is a new bright VUV FEL light source, unique in operating within the VUV region and delivering world's brightest FEL light in an energy range of 8 to 24 eV. It has applications in studying basic energy science, chemistry, physics, and atmospheric sciences.
Researchers from the University of Sydney have demonstrated a technique to predict and prevent the randomization of quantum systems, or decoherence, which destroys their useful quantum character. This achievement could help bring powerful quantum technology closer to reality.
Researchers found that well-diversified fishing communities in Alaska experienced little change in revenue despite fluctuations in fish abundance and market prices. Communities with high diversity were able to shift to different fisheries, increasing their revenue streams.
Researchers have developed a chemical-biological strategy for microRNA target identification using photo-clickable miRNAs. This approach enables the identification of target genes associated with miRNAs without disrupting their function, revealing new insights into miRNA-involved cellular regulation pathways.
Researchers found that people who recently moved were more likely to make changes to their behaviors, such as reducing energy and water use, commuting choices, and waste management. This study suggests that changing one aspect of life, like moving, can lead to broader positive changes.
A new study found that increased levels of soluble phosphorus in rivers entering Lake Erie may be linked to conservation measures, despite their success in reducing soil erosion and nutrient losses. The research highlights the need for adaptive management approaches to tackle both soluble and particulate phosphorus losses from farmland.
Researchers created genetically modified fruit flies containing reconstructed ancient genes to study the evolutionary effects of genetic changes. They found that the accepted wisdom about the molecular causes of the flies' evolution is incorrect, challenging a classic example of adaptation.
The automotive industry is shifting towards more frequent model changes and smaller volumes, requiring increased flexibility in production. Researchers are using 3D scans to generate virtual three-dimensional images of production facilities, simulating how to convert lines for new models.
Researchers at John Innes Centre identify CrNPF2.9 as key transporter of strictosidine, a central intermediate in monoterpene indole alkaloid biosynthesis; this discovery sheds light on the pathway of MIA compounds produced in the plant.
A new study of over 120,000 UK teens found that moderate digital screen use is not linked to negative effects on well-being. The researchers suggest a 'digital sweet spot' where screen time benefits teens by providing opportunities for social connections and skills. However, excessive engagement may displace important activities.
A study by Prof. Dr. Wolfgang Driever and his team discovered that specific tactile and visual stimuli activate dopaminergic nerve cells in the forebrain, affecting brain function and basic behaviour. This finding could lead to new treatments for conditions like restless leg syndrome.
The galaxy RX J1140.1+0307 has a supermassive black hole with one of the lowest known masses, yet its emission spectrum cannot be explained by current models. Scientists believe other mechanisms are at play in the interactions between the inner and outer parts of the accretion disk surrounding the black hole.
Researchers from the University of Exeter have tagged and tracked hundreds of loggerhead turtles in Greece to study their migration patterns. The results show most turtles come from nesting populations within 125 miles, but one female traveled over 1,000 miles to breed in Turkey and Syria.
The study reveals that sulfuric acid droplets formed after the asteroid impact caused long-lasting cooling, which likely contributed to the death of land-living dinosaurs. Marine ecosystems were also severely affected by the ocean circulation disturbances caused by surface cooling.
A clinical trial in Nigeria replaced biomass and kerosene cookstoves with ethanol stoves, reducing the risk of high blood pressure and cardiovascular disease in pregnant women. The study found a significant decrease in high blood pressure among women who cooked with ethanol, with risks reduced by 97% compared to those using traditional...
UC Riverside-led research quantifies rattlesnake strikes for the first time using portable high-speed cameras, capturing three-dimensional video of a snake preying on a kangaroo rat. The study reveals that snakes can greatly exceed lab observations and that kangaroo rats may use elastic energy storage to evade strikes.
A study found that children perceived as 'overweight' by parents tend to gain more weight over time, possibly due to negative self-image and attempts to lose weight. The association was seen in both Australian and Irish families, with the link not explained by other factors.
The new soy-based filter can capture nearly all pollutants, including small particles and hazardous gaseous molecules. The biodegradable material is cost-effective and has the potential to improve indoor air quality, particularly in regions with poor air quality.
Researchers at Kumamoto University find that interleukin-6 (IL-6) helps cancer cells survive radiation therapy by suppressing oxidative stress through the Nrf2-antioxidant pathway. This discovery offers new potential therapies targeting IL-6 to combat radioresistant cancers.
A new collaborative project is using a unique climate-simulating laboratory system to quickly identify promising algae strains for renewable fuels. The Algae DISCOVR Project aims to reduce the cost and time needed to move promising algal strains from the laboratory to production.
The NASA Terra satellite observed cloud tops west and north of the center of the low-pressure area reaching -70 degrees Fahrenheit, indicating strong storms. The low-level center of circulation appears to be consolidating, with multiple surface observations showing 15-20 knot winds.
Researchers found that the most successful phyla have a skeleton, live on land, and are parasites. This suggests that traits like having eyes or complex organs may not be primary drivers of species diversification. The study sheds light on why some groups have branched into many species while others remain relatively few.
Scientists have created male pigs that can produce sperm with the genetic blueprint of sought-after pigs by transplanting stem cells into surrogate animals. This breakthrough could dramatically improve pig farming efficiency and quality, as well as enhance desirable traits like disease resilience.
The proposed scheme considers vehicle shape and road width to minimize collisions and optimize path tracking. The model predictive control method effectively tracks the desired lateral position of road centerline, avoiding collisions and ensuring low energy consumption.
New research suggests that erionite's carcinogenic effect may be caused by its fibrous structure, rather than iron present in accompanying minerals. The mineralogists' findings raise questions about the role of ferrous particles in erionite's toxicity.
A study by the Centre for Addiction and Mental Health estimates that nearly 10% of women drink alcohol during pregnancy worldwide, leading to an estimated 119,000 cases of Fetal Alcohol Syndrome annually. The study also found that nearly 15 people per 10,000 have FAS globally.
Researchers discover mutations in the REEP6 gene as a significant contributor to retinitis pigmentosa, a leading inherited eye disorder. The study identifies seven new cases of patients with tunnel vision and vision loss, shedding light on the genetic basis of this devastating disease.
Researchers found that treatments don't fit a 'one size fits all' model for patients with myotonic dystrophy type 1. Targeted therapies were more effective when matched to individual symptoms, with 29% of patients benefiting from treatments such as CPAP and modafinil.
A study shows that testimony therapy plus ceremony significantly reduced symptoms of posttraumatic stress disorder, anxiety and depression among Khmer Rouge torture survivors. The intervention was found to be effective, brief, culturally adapted and suitable for low-resource contexts.
The National Institute of Food and Agriculture is providing funding to improve science education in the food, agriculture, natural resources, and human (FANH) sciences. The program aims to increase diversity and retention of students pursuing college degrees in FANH sciences.
Researchers found a significant excess of mutations in five genes previously implicated only in rare forms of epilepsy in individuals with common forms of the disorder. The study identified these genes as contributing to epilepsy risk in approximately 8 percent of people with familial non-acquired focal epilepsy.
Researchers found that climate change, rather than conflict, led to the formation of a massive dust storm in the Middle East in 2015. The storm was characterized by extreme aridity and unusual wind patterns that transported large amounts of dust over long distances.
The Austen Riggs Center is launching an MRI-based characterization program to explore complex psychiatric disorders and develop better characterizations. This project builds upon recent developments in mental health research, including the Human Connectome Project and the Research Domain Criteria (RDoC) Matrix.
A study published in Atherosclerosis journal reveals that depression poses a significant risk for cardiovascular diseases, comparable to high cholesterol levels and obesity. Researchers analyzed data from over 3,400 male patients, finding that depression accounts for roughly 15% of cardiovascular deaths.
Scientists have developed new HCV vaccination strategies using a model system, aiming to create durable and effective vaccines for all populations. The project, led by Professor Peter Simmonds, will focus on addressing the substantial societal problem of HCV infection.
Researchers at Washington State University have created a perennial grain species, Salish Blue, which combines wheat and wheatgrass. This new crop has the potential to improve soil health, reduce waste, and provide sustainable food options for the Pacific Northwest.
A recent study from Uppsala University found that systematic exchange of information between parents, preschool teachers, and child healthcare centres (CHCs) is crucial for identifying young children with mental health issues. The study introduced a new method to enhance communication between these groups, resulting in improved assessm...
A new $1 million NIH-funded study will investigate the effects of phthalates in plastic products used in pediatric intensive care units (NICUs). The study aims to assess the long-term impact of exposure to these chemicals on children's development, particularly premature infants.
A Penn Medicine study found that older adults walked 2,348 steps and 2,562 steps per day with financial incentives and charity donations, respectively. The study suggests that goal-based interventions can motivate older adults to exercise more effectively.
A University of Stirling analysis found that doing fewer repetitions of high-intensity cycle sprints on a bike can lead to greater improvements in cardiorespiratory fitness. The optimal number of repetitions appears to be just two, allowing for shorter workouts without compromising results.
Researchers found that older, fitter adults outperformed younger counterparts in memory tasks, with increased brain activity observed in regions typically declining with age. This suggests that cardiorespiratory fitness may contribute to brain maintenance and serve a compensatory role in age-related memory decline.
Researchers at the University of Freiburg discovered that dopamine release is triggered by tactile and visual stimuli in the forebrain, affecting brain function. This finding may lead to new treatments for restless leg syndrome, a condition causing unpleasant sensations during sleep.