NASA's Aqua satellite captured images of Tropical Depression Calvin before it made landfall in southwestern Mexico on June 12. The depression brought heavy rain and created flooding across several Mexican states, including Oaxaca, Guerrero, Chiapas, Tabasco, and Veracruz.
Researchers identified a biomarker that better categorizes patients who would respond to FGFR inhibitors, improving clinical trial design. Combining FGFR inhibitors with chemotherapy has the potential to improve treatment outcomes.
A long-term study found a significant link between aircraft noise and an increased risk of developing high blood pressure. Exposure to night-time aircraft noise was associated with a doubling in risk of heart flutter and stroke, with every additional 10 dB of noise linked to a 69% heightened risk of high blood pressure.
Researchers have developed a fully integrated microfluidic device that produces hydrogen fuel and converts it into electrical energy based on photocatalysis. The device is designed to be self-sustaining and can provide enough power to transmit data from a microsensor for 24 hours.
A large analysis of five major testicular cancer studies has uncovered eight new genetic markers associated with an increased risk of developing testicular germ cell tumors. The findings, published in Nature Genetics, substantially increase the number of known susceptibility genes linked to testicular cancer.
The study reveals that autumn Eurasian snowfall and surface air temperature contribute to snow variability via different pathways. Researchers found that atmospheric circulation, water vapor transport, and land-surface changes play crucial roles in shaping autumn Eurasian snow patterns.
Researchers have developed a new method to control fire blight by using a genetically modified bacteriophage (Y2) that can dissolve the slime layer protecting the Erwinia bacteria and kill it. Additionally, another variant of Y2 has been engineered to detect Salmonella by emitting light when bound to infected bacteria.
A single dual time-point PET scan can identify two important biomarkers of Alzheimer's disease: neuronal injury and amyloid load. This non-invasive method shows promise for early diagnosis and personalized treatment.
Researchers at Georgetown University Medical Center found that female mice experience a markedly reduced response to traumatic brain injury (TBI), including reduced inflammation and nerve cell death. In contrast, male mice exhibit skyrocketing inflammation and nerve cell death in the week following TBI.
Researchers discovered ZBTB48 regulates both telomeres and mitochondria, contributing to a better understanding of the human ageing process. The protein limits abnormal telomere lengthening in cells, while activating genes involved in mitochondrial function.
A clinical study published in the Journal of Clinical Oncology found that TempTraq, a wearable Bluetooth patch, can detect body temperature changes up to 180 minutes earlier than the current standard-of-care method. This early detection empowers clinicians to intervene faster and improve patient outcomes.
Research reveals Palmer amaranth life history traits influence its growth and reproduction in various cropping systems. Crop rotation and canopy better explain trait differences.
Researchers Victoria Hudspith and Claire Belcher found that different types of plants burned at varying temperatures and that certain flower shapes made them more likely to be destroyed by fire. This discovery affects the interpretation of charred flowers as a source of information about ancient flowering plants.
A study suggests that vitamin A plays an important role in the development and function of beta-cells, leading to improved insulin secretion. Researchers found that partially blocking the vitamin A receptor impaired cell survival and insulin secretion, highlighting its potential as a new target for diabetes treatment.
Researchers develop a class of small molecules that penetrate and darken human skin samples in the laboratory. The drug generates protective tans in red-haired mice, which are more susceptible to skin cancer via UV radiation.
E. coli bacteria defend themselves against toxins by forming dynamic tunnels through their cell wall, allowing them to expel intruders. This mechanism may also contribute to antibiotic resistance, prompting researchers to explore new strategies for combating resistant bacteria.
Research reveals that cellular stress enhances Th17 cell activation, increasing the risk of autoimmune diseases such as arthritis and multiple sclerosis. Inhibiting cellular stress may hold promise for reducing disease symptoms by preserving other T cell responses.
The FAU-based project 'E|Connect' aims to improve the performance and reliability of on-board networks in mechatronic systems. Researchers will investigate ways to optimize these networks for higher speeds, larger numbers of nodes, and better power delivery.
The new Dementia with Lewy Bodies Consortium will centralize research efforts and create a national, coordinated registry for clinical data. Researchers aim to find DLB biomarkers to improve diagnosis and treatment of patients with this disease.
A new study reveals that the largest galaxies in the universe have been aligned with their surroundings for at least ten billion years. The discovery suggests that these galaxies are especially sensitive to their environment and were influenced by their surroundings from a young age.
A new large-scale study found that species with faster genetic differentiation rates produce more species over time. The study analyzed genetic sequences from 17,000 individuals across 173 bird species, demonstrating a link between population differentiation and speciation rates.
A new study provides further evidence for the genetic factors underlying addictions, linking dysfunction of the CSNK1E gene to increased opioid addiction susceptibility and binge eating vulnerability. The findings suggest that shared genetic factors may underlie behavioral traits associated with addictions and eating disorders.
Researchers at Argonne National Laboratory used X-ray crystallography to solve the structure of Lassa virus glycoprotein, a key component in vaccine development. The study provides valuable insights into how the virus enters human cells, paving the way for the design of an effective vaccine.
Researchers developed a more resilient type of concrete using recycled tire fibres, reducing crack formation by over 90% compared to regular concrete. The new concrete has potential to shrink the tire industry's carbon footprint and reduce construction emissions.
Researchers have found a crystallized form of DDT that is more effective against insects than the existing one, potentially leading to the development of a safer pesticide. The new DDT crystal form can be administered in smaller amounts while reducing environmental impact.
Researchers will construct an advanced dark matter detector based on magnetic sensors, aiming to detect invisible mass in the universe. The project brings together experts in various fields to observe dark matter directly.
Scientists at Imperial College London discovered a way to target specific receptors controlling appetite in mouse brains without causing side effects. This breakthrough could lead to the development of a new type of anti-obesity medication that activates thyroid hormone receptors in the hypothalamus.
A study published in Neurology found that omega-3 supplements derived from seal oil increased corneal nerve fibre length by 29% in patients with Type 1 diabetes. This increase is considered a biomarker for small nerve fibre regeneration and may suggest the potential of this supplement to have regenerative effects.
Researchers found that ferrous sulfate increased hemoglobin concentration more than iron polysaccharide complex, and had a higher complete resolution of IDA. The study suggests once daily low-dose ferrous sulfate as a treatment option for children with nutritional iron-deficiency anemia.
A study found that birds living in prime conditions have lower evolutionary potential to cope with climate change, whereas those between extremes exhibit greater adaptability. This reduces the likelihood of survival for populations in optimal and harsh environments.
Assemblies of metallic nanoparticles behave like bulk magnets, displaying intriguing shape-dependent behavior that could improve high-density information storage technologies. The structures' magnetic behavior is influenced only by the shape of the assemblies, revealing a single bulk ferromagnet.
Researchers developed a new method to study chemical reactions at atomic scale, allowing for real-time observations of the solid-liquid interface. This technique helps improve water purification methods and understand supercapacitor performance.
Researchers have developed a method using 3D-printed patches infused with cells that offer a promising new approach to growing healthy blood vessels. The patches with pre-organized structure demonstrated improved results in reducing ischemia, while those without organization resulted in a disorganized network.
A study of cognitively normal individuals found that those with elevated brain amyloid levels were more likely to experience cognitive decline over a median of 3.1 years. The research suggests that preclinical Alzheimer's disease may represent the pre-symptomatic stage of AD.
Researchers have developed a way to increase pigmentation in human skin without the damaging effects of ultraviolet (UV) radiation. A new class of small-molecule inhibitors has been found to activate the pigmentation pathway, inducing significant darkening similar to UV-induced tanning.
Researchers have discovered a solution to evade the immune system, allowing more patients to participate in gene therapy clinical trials. The altered virus can slip past neutralizing antibodies, making it possible for up to 70% of patients previously ineligible to join trials.
A study published in The Journal of the American Medical Association found that elevated brain amyloid plaques are an early precursor to Alzheimer's disease, which can lead to faster mental decline. The research suggests that intervening against amyloid levels could slow or even stop the onset of the disease.
Researchers have developed silver nanoclusters with excellent optical properties, making them suitable for biosensing and imaging applications. The nanoclusters' ability to absorb light efficiently and withstand exposure to sunlight makes them a promising alternative to existing fluorescent tags.
Scientists use ultra-cold helium droplets to align single molecules with lasers, achieving better precision than traditional gas-phase approaches. This technique enables real-time study of chemical reactions in complex systems.
Researchers at Ohio State University discovered rapid microscopic swelling along the axons of rodent brain tissue after laboratory-induced mild traumatic brain injury. The study found that these swellings are reversible and disappear within minutes, which could lead to improved treatment for concussions.
Researchers found that nearly all sunlike stars form with a companion, but these companions often escape and merge with other stars. The study's findings have implications for the origins of galaxies and suggest that many stars are born in pairs, like our sun and its long-lost sibling.
Researchers propose that Mars' Lyot valley networks were carved by meltwater produced when hot ejecta interacted with an icy surface. The team estimates thousands of cubic kilometers of meltwater were generated, enough to shape the valleys.
Long-term daily aspirin use increases risk of disabling or fatal bleeding in people aged 75 or over. Co-prescribing proton-pump inhibitors can reduce this risk by up to 90%. Studies have shown that the benefits of long-term PPI use outweigh the risks for patients in this age group.
A new study reveals that multiple ocean surface temperature changes are the primary driver of multi-decadal global warming accelerations and slowdowns. This finding supports a more accurate estimate of future global warming rates to meet the Paris Conference's 1.5°C target.
A new study demonstrates the feasibility and safety of HuMab-5B1, an antibody that targets the cancer antigen 19-9, found on pancreatic tumors and other malignancies. The treatment shows promise for better identifying tumors and directing treatment.
UNC researchers discovered that Set2 enzyme is essential for maintaining proper transcription during cellular stress, preventing mis-expression of genes and promoting cancer initiation. The study's findings have implications for understanding cancer development and potential therapeutic strategies.
Researchers challenge existing understanding of MLL-translocation leukemia by finding that MLL2, not MLL, is the most appropriate target for drugs. The study shows that silencing wildtype MLL has no effect on disease development, but combining it with MLL2 knockout leads to significant reduction in leukemia.
A study published in PLOS Medicine found that funding from the US President's Malaria Initiative (PMI) in sub-Saharan African countries was associated with a significant reduction in under-five child mortality. The analysis, which controlled for other factors, showed an average risk reduction of 16% in PMI-funded countries.
A study published in Obesity Surgery found that only 2,112 out of 37,806 patients (5.58%) underwent subsequent body contouring procedures after bariatric surgery. The majority of these patients had higher incomes or health insurance, and the procedures usually occurred within two years after the initial bariatric procedure.
Dr Dmitry Zmeev has been awarded a £1.4M EPSRC Career Fellowship to investigate the properties of superfluid helium 3He. His research aims to understand its unusual behavior and potential applications in nano-electronics and cosmology.
A new study suggests that human embryo mortality rates are exaggerated, with many more embryos surviving than previously claimed. In vitro embryos also show poor survival rates, which may reflect the natural situation or be due to artificial environments.
In response to the ongoing Ebola outbreak in the Democratic Republic of Congo (DRC), RTI International is working closely with the Ministry of Health and other partners to strengthen local surveillance systems. The average case fatality rate for Ebola is around 50%, and there have been over 100 contacts under daily monitoring.
A recent study published in PLOS Medicine suggests that genetic variants associated with higher body mass index (BMI) are linked to lower risk of Parkinson disease. The researchers used a Mendelian randomization approach to examine the relationship between BMI and Parkinson disease, and found an 18% lower risk of Parkinson disease amon...
Researchers at Waseda University have developed an efficient alternative method for synthesizing ammonia at low temperature using surface proton hopping. This breakthrough could lead to on-demand ammonia production plants running on renewable energy, with potential applications in various industries and energy sources.
Researchers at Newcastle University have identified a mechanism that causes fatty liver disease and successfully reversed it using a pharmacological approach. By eliminating senescent cells, the build-up of unwanted fat in the liver was reduced, restoring liver function to normal.
Researchers at Kanazawa University found that transcranial direct current stimulation (tDCS) on the lateral occipito-temporal cortex (LOTC) improved mental manipulation of body part imagery. This improvement was observed in healthy adults, indicating potential benefits for exercise learning and rehabilitation outcomes.
A new OpenArray system offers simultaneous detection of multiple viruses, bacteria, and protozoan pathogens in human blood samples, demonstrating a promising tool for flexible and accurate blood screening. The device was tested with 92 donor samples and showed 95% accuracy in identifying virus-positive samples.
Researchers found a significant rise in discriminatory language against female athletes in the media, with 96 instances of microaggressions reported during the 2016 Olympics. The study highlights the need for education to reduce microaggressions and promote inclusivity in sports media coverage.
Research found that early-life exposure to severe famine as a fetus or infant significantly increases the chance of having dyslipidemia in adulthood. The association was true for women but not men, suggesting cultural differences may play a role. Severe maternal under-nutrition during pregnancy could also contribute to the increased risk.
The CorsicArchive project, funded by the German Research Foundation, uses tree ecology, hydrology and climatology to analyze past and present climate changes. The researchers aim to understand the effects of climate extremes on forest ecosystems and provide insights for forestry industry and tourism.