Researchers at MUSC found that gp96 is essential for maintaining a balanced immune system in the gut, preventing colitis. Without gp96, pAPCs become more inflammatory, leading to an imbalance of T cell populations and the development of colitis.
The NANOaers project investigates airborne nanoparticle mixtures and their impact on respiratory health. Researchers analyze the behavior of nanoparticles with other chemicals, aiming to predict their fate and potential health effects.
Researchers at Louisiana State University have developed a portable system for capturing and analyzing biomolecules from fingermarks, including DNA and explosives. The technique uses infrared laser ablation to lift molecules off surfaces without destroying them.
NASA tracked Tropical Storm Merbok's rainfall rates and 3D structure before it made landfall east of Hong Kong. The storm showed intense precipitation patterns, with rain falling at a rate of over 57 millimeters per hour in one of its rain bands.
Dr Jason Camp is investigating a non-toxic and environmentally sustainable solvent produced from waste cellulose to produce a range of medicines. His research has shown promising results using Cyrene as a solvent in the synthesis of ureas, chemical compounds important in pharmaceuticals and agrochemicals.
Researchers found that phubbing can lead to increased smartphone use and social media attachment, resulting in higher levels of stress and depression. The study suggests a vicious cycle where individuals turn to technology to regain a sense of belonging after feeling socially excluded.
Low-energy electrons affect insulators in electronic systems and cause radiation damage in human and biological tissue. Researchers have devised a technique called the aerosol overlayer method to measure electron movement, separating core and shell interactions.
Researchers at TUM and Helmholtz Zentrum München developed a method that significantly increases the chances of identifying genetic triggers in rare hereditary disorders. By sequencing both DNA and RNA, they were able to narrow down gene candidates in 10% of cases, while reducing false positives.
Researchers at the University of Alabama at Birmingham have made a groundbreaking discovery that fecal donor microbes can persist in recipients for months or years after a transplant to treat C. difficile infections. This is possible thanks to a novel method developed by the team to 'fingerprint' individual bacterial strains, allowing ...
Scientists at the University of Basel have developed a procedure that allows binding single gold atoms to polymer chains on silicone membranes. This enables the formation of ultra-thin conductive layers on silicone rubber, opening up new possibilities for medical implants.
Fossil evidence reveals a previously unknown east-west migration route for some mammals across North America, challenging previous hypotheses. Researchers propose that sea otters and potentially other animals traversed the northern edge of the Trans-Mexican Volcanic Belt to reach California from Florida.
A team of researchers has discovered a potential treatment for Duchenne muscular dystrophy by repurposing a compound originally developed to treat cancer. The compound, SU9516, works by boosting muscle repair and regeneration in affected muscles.
Researchers at Thomas Jefferson University discovered a molecule, LRP4, that plays a crucial role in maintaining the balance of excitatory and inhibitory neurons. The molecule is specific to excitatory synapses, suggesting a parallel molecule may exist for inhibitory synapses.
Researchers found over 20,000 animal bones, stone tools, and portable art objects from 10 sedimentary layers spanning 28,000 to 50,000 years ago. This timeline provides evidence of modern human activity in Europe during a period of significant change in species behavior.
Researchers at the University of Illinois have developed a new nanoscale memory cell that holds promise for successful integration with superconducting processors. The device provides stable memory at a smaller size than other proposed memory devices, eliminating magnetic-field cross-talk and enabling faster and more powerful computing.
A study led by neuroscientists found that oxytocin in the amygdala inhibits a self-defense reaction, allowing mothers to protect their young. The team manipulated oxytocin levels and observed increased defensive behavior when the hormone was inhibited.
A new study from Newcastle University shows that the exact time of neuron development and its position in the brain are key to forming neural connections. This understanding can lead to better diagnosis and treatment of developmental diseases like schizophrenia, autism, and ADHD.
A clinical trial comparing traditional ferrous sulfate with a new iron polysaccharide complex preparation found that traditional treatment is more effective in treating iron-deficiency anemia in young children. The study, published in JAMA, showed that a low-dose daily treatment can be effective in restoring normal hemoglobin levels wi...
A survey of US travelers found that most business and leisure travelers can't identify a bed bug, yet evokes a stronger response than other room deficiencies. Hotels should proactively provide information on preventing bed bug infestations to improve guest trust.
A recent study by Seth Werfel at Stanford University found that people who report taking personal energy-saving actions are less likely to support government efforts to address environmental issues. This effect occurs regardless of political ideology and may have implications for other issues as well.
The UAF Institute of Arctic Biology and College of Rural and Community Development received a five-year, $4.25 million grant to establish the Alaska Native Collaborative Hub for Research Resilience. This hub will help communities adopt culturally relevant strategies to prevent suicides.
Researchers at the University of Pittsburgh are developing new steel alloys for additive manufacturing with a focus on high-strength low-alloy steels suitable for naval construction and repair. The project aims to improve mechanical properties and corrosion resistance using integrated computational materials design.
Researchers at Wayne State University and Barbara Ann Karmanos Cancer Institute aim to improve cancer immunotherapy by using PET imaging to detect dendritic cells in tumors. This non-invasive method may help predict treatment outcome and guide patient care.
The designation as a Biosphere Reserve has improved the life quality of Urdaibai citizens by promoting well-being and sustainability, according to research. However, some residents feel the measures do not go far enough to guarantee conservation.
Researchers discovered new details about the Perseus Cluster's mini-halo, a pool of superfast particles emitting radio waves. The study revealed complex mechanisms causing the radio emission, including particle reacceleration and a powerful black hole's energy kick.
New Stanford research reveals that lesbians in Nazi Germany may have enjoyed limited toleration, with many leading open lesbian lives before being denounced. The study analyzed police investigation files from the 1940s, showing a level of tolerance and nuance to existing scholarship on the subject.
Researchers at UMD's Jewell Laboratory have developed a precision system using quantum dots to control the display of self-antigens, promoting tolerance and elimination of paralysis in pre-clinical mouse models. This breakthrough could pave the way for more selective and effective therapies for MS and other autoimmune diseases.
A Drexel University study found that art-making activities like doodling activate the brain's reward pathways, regardless of skill level or experience. The study used fNIRS technology to measure blood flow in the brain during various art activities, revealing increased activity in the prefrontal cortex and positive emotional responses.
Researchers analyzed tissue contraction to determine surgical margins for feline tumors, finding that current guidelines are often inadequate. The study suggests that more precise preoperative planning can lead to better outcomes and reduced morbidity for affected cats.
A recent study published in the Proceedings of the Royal Society Biological Sciences found that humans have a unique type of color vision that excels at detecting socially significant color variation. This ability is crucial for spotting facial color changes, such as blushing, which convey social cues.
A study of US children found that lower-income kids tend to be heavier than their upper-class peers. However, the quality and proximity of playgrounds had no significant association with childhood obesity.
A study by the University of Birmingham reveals a significant treatment gap for patients with paroxysmal atrial fibrillation, where fewer are prescribed anticoagulants for stroke prevention. This results in preventable strokes, increased risk of death and disability.
Researchers discovered a novel epigenetic signaling axis involving PRC1, microRNA, and PRC2 that regulates the self-renewal and proliferation of neural stem/progenitor cells. The study found that Ezh2 represses miR-203 expression, which negatively regulates self-renewal and proliferation but promotes neuronal differentiation.
Researchers at Stanford University School of Medicine discovered a lipid metabolite called prostaglandin E2 that activates muscle stem cells responsible for repairing damage after injury or exercise. Treating mice with PGE2 accelerates muscle repair and strength regain, while nonsteroidal anti-inflammatory drugs inhibit this process.
A new study by King's College London and the University of Bristol suggests that epigenetic changes in genes related to addiction and aggression present at birth may be linked to conduct problems in children. Conduct problems, costing £22 billion per year in the UK, can lead to chronic antisocial behavior across the lifespan.
Macrophages from CAD patients suppress T cell activation, driven by pyruvate and PD-L1. This mechanism may contribute to immune dysfunction and reactivation of long-latent viruses like varicella zoster virus.
A team of researchers used X-ray experiments and theoretical models to study the conversion of carbon dioxide into liquid fuels using copper catalysts. The findings revealed that oxygen atoms embedded near the surface of copper had a significant impact on the reaction, leading to more efficient reactions.
A study published in Academic Emergency Medicine found that the level of benefit, risk, and cost significantly influence patients' decisions to receive a diagnostic test. The researchers discovered that participants were more likely to accept a diagnostic test when the cost was lower, highlighting the impact of financial burden on medi...
Research reveals a defective immune cell's sweet tooth predisposes people to shingles, exacerbating heart disease. The connection shows how the same mechanism disabling immune response to viral infections also affects heart conditions.
A study has identified eight new genetic locations associated with an increased risk of testicular germ cell tumors. The findings, published in Nature Genetics, could help doctors understand which men are at the highest risk of developing the disease and signal them to screen those patients.
A new study by researchers at Uppsala University reveals that genetic differences between species are the key to song discrimination in juvenile songbirds. The study finds that even when exposed to songs from other species, young birds selectively learn and discriminate their own species' songs.
Status epilepticus is a neurologic emergency with neuronal damage and systemic complications, emphasizing the need for timely treatment. The latest ILAE classification of epilepsy seizures and underlying etiologies are discussed, along with management guidelines and anticonvulsant drug therapies.
Research found that irregular sleep patterns, including timing and duration, are associated with lower grade point averages and delayed melatonin release. Students with more regular sleep patterns had better school grades on average.
A study by NYU's Steinhardt School found that bilingual children excel at perceiving information about who is talking, including recognizing voices. The research suggests that speaking multiple languages enhances social perception and processing abilities.
A recent study by Columbia University's Mailman School of Public Health found that mixing booze and pot increases the risk of fatal two-vehicle crashes. Drivers who used alcohol, marijuana, or both were more likely to be responsible for causing fatal crashes compared to sober drivers. The researchers analyzed data from 14,742 fatal two...
Researchers found that metastatic breast cancer cells signal neighboring cells through the GLI transcription factor, allowing otherwise anchored cells to metastasize. The discovery highlights a promising link in the hedgehog signaling pathway, which can be targeted to reduce metastatic potential.
Researchers at UNIGE have discovered the essential role of Vps4 molecule in cell division, shedding light on the fight against cancer and HIV. The study reveals that Vps4 is necessary for abscission, a stage where cell membranes are severed, and its absence inhibits cell division and delays it significantly.
A team of scientists discovered a previously undetected health risk from volcanic plumes, finding that certain fine particles can penetrate deep into lungs, exacerbating asthma attacks. The study recommends considering both young and mature plumes when forecasting air pollution and dispersion.
Climate change threatens tropical peat swamps, which once removed carbon dioxide from the atmosphere. Peatland forests in Southeast Asia have been disappearing due to clear-cutting and drainage projects, now potentially destroying forested peatlands.
A new study from The Ohio State University Wexner Medical Center reveals that female runners with a body mass index (BMI) of less than 19 are more likely to develop stress fractures. Lighter women who suffered stress fractures took longer to recover, highlighting the importance of maintaining a healthy BMI through resistance training.
The new maize genome provides unprecedented detail on gene regulation and variation, enabling scientists to understand how the plant adapts to changing conditions. This knowledge has huge implications for breeding and expanding maize's growing range as climate change intensifies.
Researchers found that genetic testing can pick out men at increased risk of testicular cancer, who may benefit from monitoring or preventative treatment. Testing identified 1% of men at highest risk, with a 7% lifetime risk of developing the disease.
Dr. Tuuli Lappalainen is awarded a 5-year, $1.7 million NIH grant to investigate why identical genetic mutations cause disease in some individuals but not others. The study aims to understand the role of haplotype epistasis in human evolution and disease.
A large-scale study found that premature babies born at 23-24 weeks were ready for kindergarten on time, while those born 25 weeks or later performed only slightly lower than full-term infants. Nearly 2% of extremely premature babies achieved gifted status in school.
A new study found that spouses' empathic responses to their partners' pain improve the partner's physical functioning over time. Patients with spouses who provided emotional support and attention showed better balance, gait speed, and ability to rise from a chair compared to those with less responsive spouses.
A study of 10 high-income countries found that prescription drug costs varied by more than 600% across different primary care medicines. The study, published in the Canadian Medical Association Journal, highlights differences in drug prices among countries with universal healthcare.
Researchers found that using descriptive words typically used for less healthy foods increased vegetable selection by 25%. Indulgent labeling resulted in more people consuming vegetables, especially those with added sugar or savory flavors.
Researchers analyzed BACE_1, a critical enzyme in Alzheimer's disease, and proposed modifications to increase inhibitor bioavailability. Novel nanoparticle techniques are also being explored to destroy amyloid plaques, offering new hope for AD treatment.
A new review of research on acute exercise found that it improves executive function, enhances mood, and decreases stress levels in humans. Neurophysiological and neurochemical changes also show widespread brain activation after a single bout of physical activity.
A study found that Porphyromonas gingivalis, a common periodontal pathogen, may delay conception in young women. The bacteria were more frequently detected in saliva among women who did not become pregnant, and higher antibody levels were also associated with conception delays.