Researchers at the University of Liverpool have developed a computer-guided strategy that led to the discovery of two new materials in the laboratory. The algorithm uses chemical understanding of known materials to suggest new combinations of atoms, resulting in stable and synthesizable materials.
Researchers at German Cancer Research Center (DKFZ) have discovered mysterious gene transcripts that arise in treated cancer cells. These transcripts, originating from ancient viral elements, may be used as biomarkers to monitor the effectiveness of epigenetic therapy.
Research published in The Journal of Alternative and Complementary Medicine found that vaporized cannabis oil can produce cancer-causing compounds when heated. Formaldehyde levels were found to exceed the daily exposure limit with just one inhalation, highlighting potential health risks.
New research found CEOs who appeared on CNBC saw an average compensation increase of $210,239. Media appearances had a stronger impact on smaller firms and those with strong stock market performance. In contrast, larger firms saw limited gains from media visibility.
Researchers found that simultaneous genetic and chromosomal screening of a single biopsy improved pregnancy rates. The study used double genetic tests on cells taken from 1122 blastocysts, resulting in 99 pregnancies and 70 healthy births. This approach reduces the risk of implantation failure and miscarriage.
In a controlled study published in the Journal of the American College of Nutrition, participants who adopted a vegetarian diet lost nearly twice as much weight compared to those following a traditional diabetes diet. The study found that the plant-based diet led to greater reductions in subfascial and intramuscular fat.
A study analyzing PROMISE trial data found that CT angiography better predicts future cardiovascular events than functional testing, especially in identifying nonobstructive coronary artery disease. This improvement in risk prediction enables a more informed choice of testing for patients with stable chest pain.
A summer reading program showed significant improvement in children from lower-income families, with anatomical changes in the brain detected. Higher socioeconomic backgrounds were initially expected to show more improvement, but the study found that family income level was the most predictive factor.
Researchers developed a personalized peptide-receptor radionuclide therapy (PRRT) approach, which increased the radiation dose to tumors by up to three times. The treatment showed reduced side effects and improved safety profiles without compromising therapeutic benefits.
Researchers at George Washington University are testing a candidate recombinant hookworm vaccine in a Phase II clinical trial. The study aims to prove the efficacy of the vaccine against hookworm infection and its potential benefits for millions of people infected worldwide.
A Phase III trial shows that peptide-receptor radionuclide therapy significantly improves patient wellbeing, particularly in advanced midgut neuroendocrine tumors. Lutathera treatment provided more relief for patients than high-dose octreotide, with improved quality-of-life metrics and fewer side effects.
A study found that meerkat scent marks are made by bacteria, not the animals themselves. The types of bacteria and chemicals in the scent marks vary between individuals and groups, suggesting a role for microbes in animal communication.
Santoro's projects aim to engage the public with marine microbes through interactive content and activities. The Deep Sea Memory Project will explore the connection between microbes and ocean memory, potentially revealing insights into climate change and environmental records.
Scientists have identified a type of protein called Proline-Rich Homeodomain (PRH) that can help suppress the growth of breast cancer tumors. Monitoring PRH levels or activity in patients with breast cancer could be crucial for determining their prognosis.
A new technique developed by UNC School of Medicine scientists has mapped DNA damage caused by cigarette smoking at high resolution across the genome. The study provides a genome-wide map of the damage caused by benzo[α]pyrene, a chemical that accounts for about 30 percent of cancer deaths in the United States.
New research suggests that bird and bumblebee species nesting late in the year are suffering more from habitat destruction. The study found that larger birds and bumblebees are worst affected due to competition over scarce nest sites.
Glass eel larvae can sense Earth's magnetic field and orient themselves using a biological clock, allowing them to migrate towards the coast. This study sheds light on the mechanisms of eel migration and has implications for our understanding of other species' navigation behaviors.
Researchers found that combining peptide-receptor radionuclide therapy (PRRT) with a PARP inhibitor significantly slows the growth of neuroendocrine tumors. The treatment combination induced more cell death and inhibited cell proliferation in both gastroenteropancreatic and bronchopulmonary NET cell lines.
A review paper suggests that certain traditional Chinese medicines show benefits for cardiovascular health conditions such as hypertension and atherosclerotic cardiovascular disease. These medications have antihypertensive effects and a good safety profile, making them a potential alternative for patients intolerant of or who cannot af...
A new study published in Pediatrics found that children with cochlear implants who received limited or no sign language exposure had better outcomes in speech perception, speech intelligibility, language, and reading. The study suggests that oral communication may be more beneficial for young cochlear implant recipients.
A team of chemists led by Carnegie Mellon University's Rongchao Jin developed a site-specific surgery method to precisely tailor nanoparticles' properties. The technique, published in Science Advances, increases photoluminescence by about 10-fold and enhances catalytic activity.
A new USC study found that a poor diet, combined with the ApoE4 gene variant, can increase the development of Alzheimer's plaques in mice. The study suggests that lifestyle factors such as diet and exercise may play a role in regulating the risk of Alzheimer's disease.
Researchers created a new computing system that employs electronic oscillators to solve graph coloring tasks, a type of problem that challenges modern computers. The system works by harnessing the natural ability of oscillators to synchronize and operate at different phases, mimicking the solution to a graph coloring problem.
A team of international researchers has identified seven risk genes for insomnia, revealing the genetic basis of this common health complaint. The study found a strong genetic overlap with anxiety disorders, depression, and neuroticism, suggesting that shared biological mechanisms contribute to insomnia and these traits.
Researchers developed a 3-D crystal structure of the disease's molecular interactions with a neural receptor, providing a clear view of how it attacks and destroys proteins. The model could accelerate research and lead to new therapies for myasthenia gravis, which affects an estimated 36,000 to 60,000 Americans annually.
Researchers identified that the CMG2 protein binds and controls collagen VI levels, leading to its accumulation in tissues causing painful deformities. The study provides new insights into the physiological function of CMG2 and demonstrates its interaction with collagen VI.
Researchers at OHSU developed a process to engineer new blood vessels in teeth, creating better long-term outcomes for patients. This innovation eliminates the need for synthetic biomaterials and restores biological response, potentially leading to improved tooth survival rates.
Researchers from Case Western Reserve University proposed a new method to calculate and correct short-circuit errors in large-scale distribution systems. The method, which was published in IEEE/CAA Journal of Automatica Sinica, uses real-time simulations and modeling to optimize the system in just 74 milliseconds.
College women who endorse traditional gender stereotypes and music media's degradation of women are more likely to engage in unhealthy sexual relationships. Acceptance of these attitudes can lead to less consent negotiation and refusal of unwanted advances.
Researchers found that current assessments are not keeping up with clinical trial advances, highlighting the need for improved treatment outcome measurement tools. Most outcome measures in FXS clinical trials received only a moderate rating due to limited information on reliability and validity.
Researchers at The Ohio State University have discovered that blows to the head can cause small swellings along the length of neuronal axons. This finding provides novel mechanistic insights into the initial stage of a new type of neuronal plasticity in health and disease.
Researchers have developed new breast cancer risk prediction models to identify patients at higher risk of developing occult cancers not visible on mammography. The clinical trial, funded by the National Institutes of Health/National Cancer Institute, aims to significantly increase cancer detection rates through MRI screenings.
Tropical Storm Merbok formed in the South China Sea on June 11, with NASA-NOAA's Suomi NPP satellite providing visible-light images of the storm. The Joint Typhoon Warning Center predicts quick dissipation as Merbok interacts with Hong Kong's rugged terrain.
A new study from the University of Pennsylvania's Damon Centola refutes the classic theory that groupthink destroys the wisdom of crowds. In egalitarian networks, where everyone has equal influence, individuals help each other get smarter, leading to a striking improvement in the intelligence of the group.
Researchers found that Zika viral load and dengue antibodies were not associated with severe symptoms or fetal harm, contradicting previous theories. The study's findings suggest a lack of correlation between the amount of virus in the blood and severity of symptoms in pregnant women.
A study published in JAMA Pediatrics found that adolescents with ADHD are licensed to drive less often, increasing their crash risk. The study analyzed over 18,000 patients and discovered a 35% lower licensure rate among those with ADHD.
Researchers have identified histologic subtype distinctions and heterogeneity of neurofibromatosis type 1-associated tumors through immune profiling. The findings suggest potential targets for T cell-based immunotherapies, but also highlight the complexity of tumor heterogeneity within subtypes.
A study in 20 countries found that bats harbor over 3,200 coronaviruses, most of which have yet to be detected. The viruses are concentrated in areas with high bat diversity, suggesting coevolution or adaptation.
Astronomers using ALMA have detected the rotation of a massive baby star's outflow, shedding light on how rotational momentum is dissipated. The observation confirms the 'magnetocentrifugal disk wind model,' which suggests that gas in the rotating disk moves outward and upward to form outflows.
A phase 2 double-blind study found that brexanolone reduced HAM-D scores by 21 points in women with severe PPD, compared to an 8.8-point reduction in the placebo group. The medication was generally well-tolerated and showed sustained effects beyond a 30-day follow-up period.
A recent study published in CANCER found that Asian women are less likely to receive timely follow-up tests after an abnormal mammogram compared to non-Hispanic White women. The study highlights disparities in breast cancer screening and outcomes among Asian ethnic groups, with Vietnamese and Filipino women facing the longest delays.
Pomper is recognized for his work on developing new imaging agents targeting cancer and central nervous system processes. He oversees several federally funded programs at Johns Hopkins, advancing the field of molecular imaging.
Researchers demonstrated the efficacy of targeted photodynamic therapy (tPDT) to treat prostate cancer before and during surgery, using a PSMA-targeting agent coupled with photosensitizers. The technique optimizes prostate cancer care by allowing visualization of tumors prior to surgery and providing real-time guidance to surgeons.
Fowler has made significant contributions to brain research, developing the radiotracer F-18-FDG to measure brain glucose metabolism non-invasively in humans. Her work has facilitated advances in the study of the human brain and malignant tumor detection.
A KAUST-led team reveals a short regulatory gene that adapts to dynamic environments by tagging genes for repression. This discovery offers a new paradigm for gene regulation, linking the genome with the environment and providing insights into cellular plasticity.
A new study reveals that lianas prevent canopy trees from producing fruit, reducing the availability of a critical food resource for tropical animals. The effects of removing lianas are dramatic, with a 173% increase in canopy tree production five years after removal.
Researchers developed a scanner that unites optical, radioluminescence, and photoacoustic imaging to evaluate thin-cap fibro atheroma (TCFA) in the earliest stages. This could lead to a paradigm shift in coronary artery disease diagnosis and assessment.
Researchers found that participants with higher fasting plasma glucose levels lost more weight on a high-fiber, low-glycemic diet compared to those with lower blood sugar levels. Participants with high fasting blood glucose had lost an average of 9.4% body weight, while those with low fasting blood glucose had lost 4.1%.
Researchers from KAUST have developed a model predicting how climate change impacts plankton populations. Temperature, nutrient availability, and mortality rates influence the numbers of heterotrophic planktonic prokaryotes.
This study evaluated the effects of fluoride bleaching agents on human enamel. It found that fluorine bleaching agents increased the concentration of fluorine, calcium, and phosphorus ions in the enamel without altering its microhardness.
A study found that brain receptors involved in addiction adapt to chronic drinking by reducing their bioavailability, but return to normal after detoxification. This can serve as a predictor of long-term sobriety success.
The grants will support pre-clinical and clinical diagnostic and therapeutic research, including the development of new imaging agents and clinical trials on therapy safety and efficacy. The Brain SAFTIE initiative aims to identify gaps in existing knowledge and facilitate collaboration among experts.
Researchers found that blood sugar and fasting insulin biomarkers predict weight loss success. For people with prediabetes, a fiber-rich diet without calorie restriction is effective, while those with type 2 diabetes benefit from a diet rich in healthy fats.
A new review investigates the relationship between pain and opioid misuse, revealing that pain can drastically change the brain's natural opioid system. The study aims to understand how pain affects addiction treatment, with the ultimate goal of developing more effective treatments for chronic pain.
A novel study found that short duration of breastfeeding and maternal obesity are associated with an increased risk of nonalcoholic fatty liver disease (NAFLD) in adolescents. Breastfed infants who were fed infant formula milk before six months had a 40% increased likelihood of NAFLD.
Scientists worldwide agree on a dictionary of terms to study sedentary behavior, an emerging global public health priority. The consensus definitions aim to facilitate research interpretation and comparison, helping to reduce confusion and advance the field of sedentary behavior research.
A large pragmatic trial found that checking finger-stick blood sugars did not offer significant advantages in blood sugar control or quality of life for non-insulin treated type 2 diabetes patients. The study suggests that the costs of home blood glucose monitoring may outweigh its benefits for this population.
The journal published two ultraviolet radiation datasets covering China, providing long-term measurements from 1961 to 2014. This move aims to promote translational applications for the general public by making atmospheric and physical oceanographic data traceable and citable.
Researchers at Ulsan National Institute of Science and Technology (UNIST) have developed a new type of carbon nanomaterial that can change shapes and colors depending on the solvent used. The material exhibits tunable emission spanning a wide range of colors in various solvents.
A randomized trial found that self-monitoring of blood glucose levels in patients with non-insulin-treated type 2 diabetes did not improve glycemic control or health-related quality of life after one year. The study suggested that SMBG should not be routine for most patients, contradicting existing practice.