Christian S. Stohler, Columbia University College of Dental Medicine dean, received the Jack Hein Public Service Award for his leadership in supporting and advancing oral health research. He led a successful transition integrating oral health advocacy operations with the AADR, amplifying voice on Capitol Hill.
The Anthropocene Working Group addresses geological critics' concerns about a new epoch, emphasizing the presence of distinctive strata. The group's research highlights human-driven transformations with physical evidence, such as artificial radionuclides and plastics.
Scientists at IBS have proposed a hypothetical portal connecting two possible dark sector particles: dark photons and axions. This discovery could lead to reinterpretation of previous data and potentially breakthroughs in axion and dark photon searches.
The ACMG Foundation/Shire Laboratory Geneticist Fellowship Awards and Clinical Genetics Residency Program supports the training of future medical geneticists. The program provides funding for three specialties: Clinical Genetics Residencies, Clinical Laboratory Fellowships, and Medical Biochemical Genetics Subspecialty Fellowships.
A new study by University of Cologne researchers reveals that herbivores have a significant positive impact on plant biodiversity. The interaction between nutrient availability and consumer species diversity is found to be crucial in maintaining producer diversity, highlighting the importance of preserving this balance for ecosystem he...
Researchers have identified a key step in the molecular process of DNA repair and found a treatment to reverse aging, improve DNA repair, and potentially mitigate effects of cosmic radiation. Human trials are set to begin within six months.
Brigham Young University researchers have created flexible glass membranes that can bend and flex at the nanoscale. These membranes will enable lab-on-a-chip devices to move small biological particles like proteins, viruses, and DNA, leading to more accurate and rapid disease diagnosis.
A new mathematical framework explains why plants have different shapes, attributing it to a 'sense of self' and its interaction with gravity and environment. The study uses simple ideas to quantify plant stem diversity.
Researchers at EPFL develop synthetic methods to introduce chemical modifications on huntingtin, reducing its toxicity and aggregation. The study reveals key findings on the relationship between post-translational modifications and huntingtin structure, function, and toxicity.
Researchers found no relationship between family-meal frequency and weight but did find that eating home-cooked meals without TV or video significantly lowered obesity odds. Engaging in both healthy practices every time they ate family meal was the lowest risk.
Researchers directly observed two Milky Way-like galaxies when the universe was eight percent of its current age, surrounded by massive hydrogen gas halos. The galaxies are forming stars at moderate rates and already rotating, similar to today's giant spiral galaxies.
The article reviews workplace policies that affect breastfeeding and recommends key elements of a successful policy, including breaks for pumping, storage facilities, and education. Nurse practitioners play a crucial role in promoting continued breastfeeding after returning to work.
The report recommends increasing US spending on solar R&D, encouraging international collaborations with China, and reforming federal policies to prioritize cost reduction. The researchers argue that the US should capitalize on its strengths in research and development while addressing concerns around intellectual property protection.
Researchers created a three-dimensional map of Mycoplasma pneumoniae's circular chromosome, revealing a previously unknown layer of gene regulation. The study found that the tiny bacterium's genome is organised into distinct structural domains, each containing genes turned on or off in a coordinated way.
The American Chemical Society's 253rd National Meeting & Exposition will explore the impact of advanced materials, technologies, and systems on energy, environment, and health. The plenary talks will emphasize collaboration between industry and academia to foster sustainable development.
Researchers at UC Berkeley have created a microfluidic device that can analyze individual tumor cells for specific cancer protein biomarkers. This technology could allow doctors to monitor treatment response through regular blood draws, potentially leading to more precise cancer diagnoses.
University of Waterloo researchers developed a 17-question survey, Mealtime Audit Tool (MAT), to identify barriers to food intake in hospitals. The tool aims to improve nutrition practices and reduce malnutrition rates, potentially shortening hospital stays.
The global rise of multidrug-resistant tuberculosis (TB) poses a significant threat to progress made in controlling the disease. The emergence of extensively drug-resistant TB is associated with high mortality and is a serious public health problem.
Heavy rainfall in Peru led to extensive flooding, landslides, and loss of life. NASA's Global Precipitation Measurement mission provided data on precipitation rates and totals, revealing storms dropping heavy rain at rates of over 137 mm per hour.
A study found that midazolam was more effective in treating seizures than other benzodiazepines and was adopted by ambulances across the country, increasing from 26.1% to 61.7% between 2010 and 2014. The rate of adoption accelerated after a clinical trial's publication, with EMS agencies adopting midazolam at a rate of 8.9% per year.
A study from UC Berkeley found that Zika's decline before the Olympics was foreshadowed by seasonal patterns of similar diseases. Despite this, vulnerable populations in urban slums continue to be affected, highlighting the need for targeted public health efforts.
Researchers from UPV/EHU-University of the Basque Country and Boulder group successfully designed a robust 2-ion quantum logic gate that operates in a microsecond. This breakthrough could lead to advancements in quantum technology, including secure communications.
The Flame Refluxer technology, developed at Worcester Polytechnic Institute with funding from BSEE, demonstrates potential for efficient oil burning while reducing emissions. The tests showed hotter fires consuming more oil, cleaner emissions, and less burn residue.
Researchers found that most dengue virus infections occur within neighborhoods and are transmitted by the same family of mosquitoes. The study suggests that large urban centers can spread dengue diversity, which can be dispersed to other areas.
A new study finds that immigrant children who arrive before age 10 develop occupational skills similar to those of native-born Americans. In contrast, older arrivals from languages distant from English focus more on math and STEM fields, leading to occupational segregation.
A new study projects a 50% increase in conducive weather conditions similar to those in January 2013, leading to more frequent severe haze events in Beijing. The researchers developed an effective Haze Weather Index (HWI) to represent such conditions, which are influenced by large-scale circulation changes and climate change.
Researchers at Rice University have developed an artificial photosynthesis material that can split water into hydrogen and oxygen using sunlight. The catalyst, made from iron, manganese, and phosphorus, is efficient and easy to manufacture, paving the way for a clean renewable source of hydrogen fuel.
Researchers have developed a new method to deliver large and diverse cargos directly into cells with high efficiency and no lasting damage. The team used gold pyramid-shaped microstructures and nanosecond laser pulses to create brief pores in the cell membrane, allowing molecules to diffuse into the cell.
A new Yale-led study reveals significant market potential for renewable thermals in Connecticut, with the technology able to competitively serve 19% of thermal demand. To realize this potential, public policy and financing tools are needed to spur consumer demand.
Researchers at the University of Bristol have developed a technique to manufacture immortalized red blood cells, which can be cultured indefinitely and differentiated into mature red blood cells. This breakthrough could potentially provide a safe source of transfusions for people with rare blood types and areas with inadequate blood su...
A new study proposes a simple rule of thumb, or 'carbon law', to rapidly reduce carbon emissions. The authors argue that halving emissions every decade could catalyze disruptive innovation and help achieve the UN's Paris Agreement goal of limiting global temperature rise to well below 2°C.
Researchers have determined the three-dimensional structure of the human protein responsible for cystic fibrosis. The study reveals similarities with its zebrafish counterpart, allowing for a deeper understanding of how the protein functions normally and leads to the disease.
Researchers have developed fluorescent compounds that demonstrate how membrane lipids hop in and out of specialized regions called raft domains at unexpectedly fast rates. This discovery reveals a large paradigm shift in the research field, suggesting that raft-associated lipids are not stably localized in these domains.
Scientists studied the effect of noble gas argon on pressurized hydrogen and found that it did not ease the transition to a metallic state. The team brought argon-doped hydrogen up to extreme pressures, but observed no structural changes, indicating that argon is not the ideal facilitator for metallic hydrogen.
Researchers at MIT create a new 3D-printed device that responds to mechanical stresses by changing the color of its surface, inspired by the golden tortoise beetle. The device has potential applications in flexible sensor-laden robots and self-assembling structures.
A study found that only 65% of youths with type 1 diabetes and 42% of those with type 2 diabetes had undergone an eye examination by six years after initial diagnosis. Groups at reduced likelihood of screening include racial minorities and economically disadvantaged youth.
Research at Technical University of Munich found that diabetes causes loss of small blood vessels around the heart, affecting cardiac muscle. Genetic therapy promoting pericyte growth may offer a remedy, providing new perspectives for treating patients.
A study by Aarhus BSS at Aarhus Universit found that people who perceive the world as conflict-ridden and are predisposed to aggressive behavior are more likely to support dominant leaders. This support is driven by a desire to escalate conflicts aggressively rather than fear or new situations.
A genome sequencing study for rare parathyroid carcinoma has identified mutations in known cancer-related genes and pathways, providing a clear view of genetic mechanisms involved. This in-depth characterization could lead to the first therapy options for patients with this deadly cancer.
A recent study found that non-breeding ravens form highly dynamic social groups, often meeting at rich food sources and common night roosts. These interactions may have driven brain evolution in ravens, similar to humans who prefer to explore or stay in one place.
Researchers found that mucin proteins fail to unfold normally in CF airways due to dehydration, leading to thick and sticky mucus. This understanding could lead to therapies targeting the abnormal compact form of mucin proteins, such as rehydrating the airway lining with hypertonic saline.
Researchers at Saint Louis University are developing a potential exercise pill for diabetes and obesity by targeting nuclear receptors. The study aims to optimize two drug compounds, REV-ERB and ERR, which have shown promising results in improving muscle metabolism and reducing the risk of chronic diseases.
Scientists have discovered a new type of memory effect in transition metal oxides, which could lead to breakthroughs in security technology. The phenomenon allows for the creation of multiple memories in a single physical space, making it potentially useful for secure data storage and encryption.
A study published in Neurobiology of Sleep and Circadian Rhythms found that sleep-deprived individuals struggle to recognize subtle facial expressions of happiness and sadness. However, their ability to identify more primitive emotions like fear and anger remains intact.
Researchers developed a comprehensive mathematical model of the deadliest malaria parasite Plasmodium falciparum metabolism. The model accurately integrates genetics and metabolism data, predicting which genes are indispensable for every biological function in the parasite.
Leroy Hubert, Jr., Ph.D., was awarded the David L. Rimoin Inspiring Excellence Award for his research on a novel diagnostic biomarker for Peroxisomal Biogenesis Disorder. The award recognizes his contributions to medical genetics and genomic medicine.
A new study published in JAMA Oncology found that female adolescent and young adult cancer survivors have a higher risk of adverse birth outcomes, including preterm birth and low-birth weight. The study also suggests an increased likelihood of cesarean births among this population.
A pilot study conducted by Thomas Jefferson University found that a virtual environment education program significantly reduced anxiety and increased comprehension in patients receiving radiation therapy. The program used simulated environments to teach patients about their treatment, resulting in improved confidence and satisfaction.
A recent European Society of Cardiology study found that cardiac lead extractions are safer in high-volume centers compared to low-volume centers. The study, which included data from over 3,500 patients, found that extraction in a low volume center was associated with a doubled risk of death during the hospital stay.
Researchers developed a custom-built microscope to study living nerve synapses, resolving events in the synapse with high precision. They found that the active zone is more like a rain shower than a single jet, with about 10 locations reused too often and a limit to how quickly these sites can be reused.
Sureni V. Mullegama received the ACMG Foundation/PerkinElmer Diagnostics Travel Award for her platform presentation on Diagnostic Utility of Clinical Exome Sequencing in Autism Spectrum Disorder. She is currently a second year ABMGG Clinical Molecular Genetics Fellow at UCLA.
A global 'carbon law' aims to halve carbon emissions every decade, peaking by 2020 and falling to zero by 2050. The roadmap also calls for rapid adoption of renewable energy, carbon removal technologies, and sustainable agriculture practices to achieve this goal.
The study found that freestanding emergency departments charge significantly higher prices than urgent care centers, with average costs ranging from $1,351 for common diagnoses to $2,199. This can lead to substantial out-of-pocket costs for patients and increased health care costs for insurers.
Experts call for improved surveillance, latest testing technology, and further research on glyphosate's impact on human health and the environment. The current safety standards may fail to protect public health and the environment from potential harm.
Researchers from Swansea University developed bespoke collars with accelerometers to track baboon behavior. The new technology allowed for precise tracking of the baboons' movements and behaviors, revealing over 90% recognition of individual behaviors without direct observation.
A new study describes the key mechanism in the brain that allows animals to recognize and react to subtle sensory signals. In a mouse model, detecting a faint screech or a tiny black speck can signal the presence of a hawk, highlighting the importance of multisensory integration.
Researchers at Stockholm University will receive prestigious ERC Advanced Grants for innovative projects tackling dark matter detection, social-ecological interactions, and the impact of social media on Chinese society. The grants support interdisciplinary approaches to tackle complex global challenges.
Researchers developed facial analysis technology to diagnose 22q11.2 deletion syndrome, a rare genetic disease affecting 1 in 3,000 to 1 in 6,000 children. The software correctly diagnosed the disease in 96.6% of cases across different ethnic groups.
Research found that nearly three-fourths of US remaining smokers have low socioeconomic status, including no college education, health insurance, or disability. These individuals face higher challenges in quitting smoking due to limited access to cessation-supporting services.
A new diagnostic model called Hierarchical Taxonomy of Psychopathology (HiTOP) aims to correct limitations of traditional models like DSM-5 by using a dimensional and hierarchical approach. This approach can lead to more meaningful decisions and advance research efforts into the causes and treatments of mental disorders.
Researchers developed a computer program to diagnose cancer and locate tumors in blood samples, with an accuracy rate of 80% for early-stage cancers. The program uses molecular patterns in cancer DNA to identify the type and location of cancer.
A new study from the University of South Carolina found a gastrointestinal link to Gulf War Illness, potentially explaining both gastrointestinal inflammation and neurological symptoms. The research suggests that altering the intestinal microbiota may lead to improved treatment options for GWI.
A new study from MU researchers has identified a protein that can be targeted to decrease post-heart attack injury and prevent heart failure in a mouse model. The research used ultrasound technology to deliver a protein inhibitor directly to the hearts of mice, resulting in a 72% decrease in heart damage compared to control groups.
A new analysis reveals that dialysis patients are being screened at a higher rate than their counterparts without kidney failure, with the healthiest patients being more likely to receive screening. The findings suggest that there is substantial over-screening among patients on dialysis, and physicians should carefully evaluate patient...
Researchers compare arm anthropometry measures to BMI to determine nutritional status in leukemia survivors. Arm measurements distinguish between fat and muscle mass, providing a valuable tool for assessing muscle loss.
Allison Mitchell, MS, CGC, has received the ACMG Foundation Carolyn Mills Lovell Award for her work on clinical implementation of novel, preemptive pharmacogenomic testing for newborns. The award recognizes genetic counselors' expanding roles in genomic medicine and their contributions to patient care.
A new mathematical model of Plasmodium falciparum's metabolism reveals its essential genes and thermodynamic bottlenecks, enabling potential mechanisms to target with drugs. The model integrates genetics and metabolomics data, allowing for the formulation of testable hypotheses and accelerating novel antimalarial drug discovery.
A team developed a new way to sequence genomes, assembling the Zika virus mosquito genome for less than $10,000. This allows for rapid creation of reference genomes for all species, including humans, tumors, and patients, enabling better diagnosis and treatment.
During the three-month campaign, scientists will validate GOES-16's advanced instruments using measurements from planes, ground-based sensors, unmanned aircraft systems, the International Space Station, and other sources. The goal is to ensure precise data for weather forecasting, severe storm warnings, and space weather predictions.
Dr. Tamanna Roshan Lal, a board-certified Pediatrician, received the $75,000 award to support her clinical genetics subspecialty training in biochemical genetics. The fellowship will provide advanced training in Clinical Biochemical Genetics and Lysosomal Storage Diseases.
Researchers found that antibiotics like trimethoprim induce a stress response in bacteria, protecting them from acidic damage. This cross-protection mechanism increases the survival chances of bacteria exposed to antibiotics and other environmental stresses.
Researchers from Baylor College of Medicine discovered that OTUD6B gene mutations cause a spectrum of physical and intellectual deficits. The study found 12 individuals carrying mutations in OTUD6B with similar clinical characteristics, including severe intellectual disability and cardiovascular problems.
Researchers at the University of British Columbia found dairy cows are highly motivated to be outside, working equally hard to access pasture as they do to fresh feed. The study's findings support previous research that public opinion of a good life for cattle involves outdoor grazing access.
A comprehensive review article explores cytokine regulation of fibroblast behavior and extracellular matrix in the lung, shedding light on chronic inflammation. The study highlights the role of metabolic changes, age, and epigenetic mechanisms in affecting fibroblast activity and immune system cell populations.
Researchers found that antibody production plays a limited role in clearing intestinal infection, and the immune response matures too slowly to fight off the bug within six weeks of age. Vaccines focusing on cell-mediated immunity or speeding up antibody production may offer promising solutions to controlling Campylobacter.
A new study by Johns Hopkins scientists reveals that nearly two-thirds of cancer mutations are caused by random DNA copying errors. The researchers developed a mathematical model based on DNA sequencing and epidemiologic data, estimating that 66% of cancer mutations result from copying errors.
Researchers at TUM have developed a method to construct custom DNA-protein hybrid structures using genetically encoded proteins and DNA. This approach allows for the creation of complex shapes and spatial arrangements that can be used to investigate fundamental processes in cell biology and biotechnology.
Michigan State University is using a $727,000 grant from the National Institutes of Health to study the connection between fish genes and human medicine. The team, led by Ingo Braasch, is focusing on the spotted gar, a fish with a similar genome to humans and zebrafish.
Scientists discovered a novel virus that weakens fungal incompatibility, allowing for transmission of unrelated viruses. This breakthrough could aid in controlling fungal diseases using viruses as a strategy.
The Benioff Ocean Initiative has committed $1.5 million to accelerate research on reducing ship strikes and mortality of whales. Researchers estimate that 10 blue whales are killed annually in the Santa Barbara Channel, threatening a species with only 3-11% of its historic population.
Astronomers discovered a supermassive black hole weighing over 1 billion suns that was propelled out of the center of a distant galaxy due to gravitational wave energy. The estimated equivalent energy is 100 million supernovas, and the black hole travels at speeds of up to 4.7 million miles per hour.
Researchers at Mass General Hospital identified novel resistance mechanisms in patients with liver tumors receiving FGFR inhibitor treatment. The study found that different mutations within individual patients and across multiple samples could confer resistance, highlighting the need for more effective treatments.
Climate change is altering silica uptake in sugar maple trees, potentially affecting ecosystems. Warmer winters and reduced snow cover are damaging tree roots, leading to a significant loss of silica, which plays crucial roles in forest health.
The Community Champions program has a positive impact on community members, increasing communication, leadership, care, and advocacy skills in nursing students. The program's inter-professional collaborations lead to improved outcomes in underserved communities.
A review paper suggests that clinical decision tools can influence pulmonary CTA use and yield, with physician nonadherence being a major obstacle. The study found that validated rules and integrated CDS systems can help appropriate use of CTAs, but further investigation is needed.
A new study published in Scientific Reports reveals that laser energy deposited into plasma produces two low-energy but high-charge electron beams and a single high-energy beam. The beams can have thousands of times more charge than the high-energy beam, offering a novel source of charged particle beams.
Early mammals developed side-to-side jaw motion, enabling them to grind food and eat a more diversified diet. This adaptation contributed to their survival during mass extinctions.
Tropical Cyclone Caleb has formed east of Cocos Island, with NASA's Suomi NPP and Aqua satellites gathering data on the storm. The Joint Typhoon Warning Center predicts Caleb will strengthen briefly before turning west and dissipating in five days.
A study by NYU's Steinhardt School found that second-generation Asian American adolescents benefit less from academic social support than others, with the influence of parents, friends, and teachers being inconsistent. Despite this, they still have strong expectations for college attendance due to high parental and teacher expectations.
Panos N. Papapanou, a Columbia University dental scientist, has received the International Association for Dental Research (IADR) Award for his diverse and prolific contributions to periodontal disease research.
New University of Michigan research finds people use generic-'you' to make meaning from personal experiences, helping them view events as more distant. The study suggests this ability allows individuals to derive broader meanings from their own experiences.
A team of researchers has developed a new method, called 3D genome assembly, that can create a human reference genome from scratch for less than $10,000. This technology allows scientists to assemble the genome of Zika virus-carrying mosquitoes at a fraction of the cost and time required by traditional methods.
Scientists at UTMB and Duke University Medical Center found a new gene interaction that increases the risk of developing multiple sclerosis. This discovery could lead to more accurate tests to identify those at greatest risk and potentially uncover new avenues for treatment.
A study published in the American Journal of Medical Genetics describes the physical and neurologic characteristics of congenital Zika syndrome in 83 Brazilian children. The findings show that microcephaly, joint immobility, and brain abnormalities are common features, with some cases having milder symptoms.
A peptide targeting senescent cells has shown evidence of improving healthspan in naturally-aged mice and mice genetically engineered to rapidly age. The approach reverses age-related loss of fur, poor kidney function, and frailty by blocking the ability of a protein implicated in senescence.
Researchers Claudia Kawas and Kristine Yaffe received the 2017 Potamkin Prize for their work on Alzheimer's disease epidemiology in the oldest-old population. Their studies highlight the critical role of modifiable risk factors in dementia prevention.
A new study recommends that pharmacies offer naloxone universally to patients taking opioid medications, without a prescription requirement. This could lead to a significant decrease in opioid-related overdose deaths.
Researchers from Michigan Medicine have identified a novel strategy to target the genetic anomaly that occurs in half of all prostate cancers. They developed large molecule peptides that can effectively target and degrade the ERG fusion with little impact on regular cell function.
Researchers at Uppsala University have discovered that antibodies against cartilage protein collagen II are associated with a good prognosis in rheumatoid arthritis. The study found that patients with these antibodies showed increased signs of inflammation during the first six months after diagnosis, but no difference later on.
A study published in the Journal of the American Geriatrics Society found that poor oral health and food scarcity are major contributors to malnutrition in older adults. The research suggests that linking patients in need to existing food assistance programs, such as Meals on Wheels, can help address this issue.
The grant will support a 'Research Experiences for Undergraduates' program at FAU's SNMREC, focusing on ocean current resource assessment and system design. Student scholars will engage in hands-on research activities, seminars, and career mentoring.
Researchers developed a gene therapy that restored balance and hearing in genetically modified mice with Usher Syndrome. The study's positive results suggest potential for treating various inherited vestibular and hearing disorders in humans.
Scientists at UVA have discovered an unexpected connection between the immune system and the testes, which may explain why some cancer vaccines are failing to work. This finding could lead to new treatments for autoimmune disorders and male infertility, as doctors target specific antigens released by the testes.
Researchers used ALMA to detect emissions from two distant galaxies, revealing massive, dusty systems with high star formation rates and extended layers of gas. The galaxies are embedded in a large halo or disk of neutral hydrogen gas, indicating rapid growth and evolution.
The Keck School of Medicine is exploring the link between GERD and esophageal cancer, with a focus on inflammation, injury, and repair in the esophagus. The research aims to better understand how myofibroblasts contribute to esophageal cancer development.
Researchers have developed an adsorbent material from orange and grapefruit peels that can effectively remove heavy metals and organic compounds from wastewater. The new material has great potential as a sustainable alternative for industrial water treatment processes.
Researchers developed a modified Hi-C technique to identify incorrect scaffold positions and anchor sequences, achieving 99% genome assembly accuracy for human genomes. The technique was applied to assemble the genomes of two mosquito species, revealing shared ancestry that could aid in controlling disease-carrying vectors.
Researchers have identified a new molecular target, OR51B4 olfactory receptor, in colorectal cancer cells, which can be activated by the odorant troenan. This activation leads to inhibition of tumour growth, slowing down cell proliferation and increasing apoptosis.
Researchers developed high-speed computational software 'Parallel STEPS' to model neuronal interactions and functions. The new approach achieved significantly improved performance, enabling faster simulation of complex models and revealing new insights into individual neuron behavior.
A new diagnostic model, Hierarchical Taxonomy of Psychopathology (HiTOP), has been proposed to address fundamental flaws in the current DSM-5 model. HiTOP allows for a continuous, dimensional assessment of psychopathology, enabling more personalized treatment and recognition of significant problems.
Researchers found no association between mosquito abundance and dengue virus risk, but longitudinal indicators showed individuals living with mosquito evidence were more likely to contract dengue. Alternative surveillance frameworks incorporating human outcomes may be necessary for effective dengue control programs.
Researchers at Rice University have developed a new material that balances carbon dioxide sequestration and methane selectivity in natural gas production. The filter, made with a polymer-based sorbent, achieves optimal performance by adjusting the ratio of potassium, oxygen, and hydrogen activation reagents during processing.
Researchers at U of A have identified a potential target for treating multiple sclerosis by discovering an underlying defect in brain cells. The study found that two sub-components within a cell are miscommunicating in patients with MS, triggering dysfunction and toxicity for brain cells.
Researchers discovered that thin parts of neuronal membranes are vulnerable to amyloid-beta protein, which builds up in Alzheimer's disease. The study found that thinner membrane fragments allow plaque to penetrate the cell, leading to cell death and memory loss.
Scientists from WCS have discovered a new species of wild ginger, Aframomum ngamikkense, in the Kabobo Massif, one of Africa's most biodiverse sites. The discovery underscores the importance of conservation efforts for this region, which has already yielded eight endemic species.
A study by UNC Lineberger Comprehensive Cancer Center found that women diagnosed with cancer during their childbearing years are at a higher risk of delivering preterm and having babies with low birth weight. The study identified potential risks for mothers who are cancer survivors, including a greater risk of cesarean section deliveries.
Berkeley Lab researchers develop first 3-D atomic-scale model of P22 virus that identifies critical protein interactions crucial for its stability. The successful rendering allows peeking inside the virus' protein coats at resolution.
Researchers at Thomas Jefferson University found significant changes in dopamine and serotonin transporters after a seven-day spiritual retreat, leading to increased positive emotions and self-transcendence. The study suggests that such retreats could prime the brain for spiritual experiences.
Researchers at Silicon Studio developed an algorithm that uses 'ensemble' and survival analysis methods to predict when users will leave a mobile game. The model can automatically adapt to different games and data, enabling companies to understand user needs and design more entertaining games.
Researchers detect 75% of a typical galaxy's star formation obscured by dust, revealing surprising findings about the early universe. The Large Millimeter Telescope allows for deeper observations, pushing our knowledge of dust production and metal enrichment over cosmic time.
Researchers at Aalto University have developed a manufacturing method for electrocatalysts using one hundredth of the usual amount of platinum, reducing costs and increasing functionality. The new material has been proven to be stable and usable in laboratory conditions.
Scientists at WashU Medicine have implicated SARM1 in the self-destruction of axons, a process that leads to nerve cell damage in neurodegenerative diseases. The study suggests that blocking this pathway could slow or prevent disease progression and has implications for treating peripheral neuropathy.
Human embryonic stem cells exist in two states: naïve and primed. Researchers have identified molecular flags on these cells, allowing them to track and investigate their transition. This approach has revealed new insights into the timing and coordination of gene activity changes during reprogramming.
Researchers created a mouse model to study how cerebral malaria leads to epilepsy in children and develop treatments. The model, developed by Penn State, is the first of its kind and has potential applications for preventing seizures and sudden unexplained death from epilepsy.
A study by University of Exeter researchers found that US Republicans are less likely to be critical of Obamacare when reminded about their own medical needs. When asked to assess the performance of the Affordable Care Act in a more personal context, Republicans viewed evidence in a more balanced way.
Researchers from Tokyo Institute of Technology found that oxygen isotopic compositions of sulfate and nitrate fluctuate seasonally, reflecting sunlight-driven changes in oxidation pathways. The study suggests that these fluctuations are not influenced by ozone variations.
Researchers at MIT and Stanford develop Splinter, a system that disguises database queries to protect user privacy. The system uses function secret sharing to split queries across multiple servers, making it impossible for anyone other than the user to determine what query was executed.
Researchers at Karolinska Institutet have developed a new tool to distinguish between immature and mature embryonic stem cells. These cells hold great potential for replacing damaged tissue and understanding early embryonic development.
A study by Kansas State University researcher Emily Mailey found that new moms who followed a more flexible approach to exercise increased physical activity and perceived barriers to be less surmountable. The flexible program allowed mothers to choose their favorite exercise, increasing prolonged physical activity.
A new study reveals that circular RNAs, previously thought to be non-coding, can encode for proteins. The discovery suggests an unexplored layer of gene activity and may have implications for understanding aging and neurodegenerative diseases.
A study published in Scientific Reports found that a 2°C rise in sea surface temperature in June 2015 led to a 6°C rise on Dongsha Atoll, killing approximately 40% of the resident coral community. The researchers suggest that natural cooling mechanisms can no longer protect corals from the effects of global warming.
A new study led by University of Nebraska-Lincoln ecologist John Benson found that eastern coyotes hunt moose and other large prey far less frequently than does the eastern wolf. The findings suggest that eastern coyotes have not filled the ecological niche left vacant when the eastern wolf became threatened.
The CLUE Working Group conducted two systematic reviews to address thrombosis and hemorrhage risks after urological cancer operations and other forms of urological surgery. The studies found that anticoagulant prophylaxis is justified in high-risk patients, but not necessarily in low-risk procedures.
A new invasive species, Anolis porcatus from Cuba, has been identified in the São Paulo coast of Brazil near the Port of Santos. The species, a generalist predator, competes with native lizards for resources and could potentially harm local ecosystems.
A new study from Indiana University Center for Aging Research and Regenstrief Institute found that the intensity of hospice services was similar across nursing homes, assisted living facilities, and patient homes, but with variations in service mix based on diagnosis and location.
Scientists have developed a new technique to produce human brain and muscle cells in just a few days, allowing for the creation of millions of functional cells. This breakthrough method, OPTi-OX, enables researchers to study diseases such as Alzheimer's and Multiple Sclerosis at unprecedented purities.
The Hierarchical Taxonomy of Psychopathology (HiTOP) proposes a new classification system for mental disorders based on scientific evidence and illness symptoms. This approach addresses limitations of the DSM-5, such as unstable diagnoses and co-occurring disorders, by categorizing mental illnesses on a spectrum.
A recent study analyzing genome sequencing and epidemiologic data from 32 cancer types found that nearly two-thirds of mutations in these cancers are attributable to random errors. The researchers' approach offers a novel perspective on cancer development, highlighting the need for more research efforts focused on secondary prevention.
Research finds that dengue virus transmissions are often centered in and around homes, with a high percentage of cases related to individuals living within a short distance. The study's findings could aid in developing targeted mosquito control programs and reducing severe illness.
A network of clinical trials aims to find the right treatment for the right patient, using individual molecular profiles. The project will recruit 658 patients across the UK, with a focus on matching patients with suitable clinical trials already in progress.
A new study demonstrates that people use the word "you" in a general sense to distance themselves psychologically from negative experiences. Participants who used generic 'you' reported more psychological distance from their negative experiences, suggesting a coping mechanism.
A new study by UBC researchers found that inactive teenagers have weaker bones than their active peers. The four-year study measured bone strength and found that kids who didn't meet daily physical activity recommendations had significantly weaker bones.
Researchers at Boston Children's Hospital report achieving strong vaccine responses in newborn animals and monkeys using a new adjuvant formulation. The study demonstrates the potential for a single-dose vaccine to protect against life-threatening infections, promising to reduce infant mortality globally.
Researchers from Brookhaven National Laboratory have identified the active site in a commonly used catalyst for making methanol from CO2. They found that copper zinc oxide should give the best results, with a synergy between copper and zinc oxide accelerating the chemical transformation.