Researchers have discovered a new way to restore antibiotic susceptibility in multidrug-resistant (MDR) Klebsiella pneumoniae and Escherichia coli strains. By identifying genes essential for survival of MDR superbugs in the presence of antibiotics, the team developed innovative drugs that can defeat resistant bacteria.
A study published in Annals of Internal Medicine found that Canadians with cystic fibrosis have a significant survival advantage over American patients, with a median age of survival of 50.9 years compared to 40.6 years in the US. The difference is attributed to better healthcare coverage and nutrition in Canada.
The team successfully controlled the peaks of laser pulses and twisted light, moving electrons faster and more efficiently than electrical currents. This achievement brings us closer to developing fast 'lightwave' computers that can process information up to 100,000 times faster than current electronics.
A study led by University of Nottingham researchers found that pandemic flu vaccines are effective in reducing the number of patients hospitalized due to the illness. However, vaccine effectiveness varies depending on age, with children being more protected than adults, especially those over 50 years old.
A new study found that door and window locks offer good security with a low carbon footprint, making them the most desirable burglary prevention measure. In contrast, burglar alarms are less effective and have a high carbon footprint, producing more emissions than an incidence of burglary.
A new study by University of California - Santa Barbara researchers found that sharks can interact with humans without long-term behavioral impacts. The research used video surveys to monitor shark abundance and behavior at sites with and without a history of scuba diving, revealing no significant differences.
A study suggests that long ago, Earth's atmosphere spent about a million years filled with a methane-rich haze, clearing the way for massive amounts of oxygen. The transformation resulted in an atmosphere much like the one that sustains life on Earth today.
The Accountable Care Organization (ACO) model successfully saved Medicare $345 per person in medical costs without driving up prescription drug coverage costs. Providers' payments are aligned with performance in improving quality and reducing costs, leading to integrated care and effective treatments.
A recent study published in Annals of Family Medicine found that oral and topical antibiotics have no meaningful benefit for milder clinically infected eczema in children. Topical corticosteroids and emollient treatment led to rapid resolution of symptoms.
A recent study conducted at The Mount Sinai Hospital found that certain genetic mutations are challenging to recreate in laboratory-produced stem cells. This limitation may hinder neuropsychiatric research, highlighting the need for researchers to carefully check for retained genetic elements in newly created stem cells.
More than one third of girls marry before reaching their 18th birthday in half of the 31 countries studied, posing health risks and controlling issues.
Scientists at the University of Liverpool have shown that phage therapy can kill drug-resistant strains of Pseudomonas aeruginosa, a common cause of chronic lung infections in Cystic Fibrosis patients. The study suggests that phage therapy could be a valuable addition to treatment options for these hard-to-treat infections.
Patients cured of Hodgkin lymphoma are at a significantly increased risk of developing a second type of cancer, particularly if they have a family history of the disease. The risk remains high even 30 years after treatment, and is higher in those with specific genetic markers or a history of certain cancers.
A new study by Columbia University's Mailman School of Public Health found that B vitamins can increase plasma concentrations of folic acid, vitamin B6, and vitamin B12, reducing the impact of air pollution on the epigenome. The results have significant public health implications for regions with frequent PM2.5 peaks.
A University of Queensland-led study reveals how cobras evolved their potent flesh-eating venom alongside distinctive hoods and warning colors. The research found that cobras' venom is used both for predation and defense, with increased potency linked to warning strategies.
Brain imaging can determine whether someone is acting knowingly or recklessly during criminal activity, according to a new study. The discovery has implications for the emerging field of neurolaw and could inform punishment decisions.
Researchers found that reducing the number of species in a grassland ecosystem can cause remaining species to flower earlier, similar to the effects of climate change. The study suggests that future changes in biological timing could be much bigger than expected, with potential cascading effects on ecosystem dynamics.
Researchers have developed a new method to create antibodies with consistent sugar groups, enhancing their ability to signal the immune system. This breakthrough could lead to more effective therapies for cancer and autoimmune diseases, with the potential for customized antibody production.
Researchers at the Francis Crick Institute demonstrate a network of chemical reactions mimicking the Krebs cycle, a crucial process in cellular life. The findings suggest an enzyme-free metabolic pathway could have emerged four billion years ago, sparking the development of life on Earth.
The new study reconstructs historical ocean subsurface temperature change with improved accuracy, revealing larger ocean energy accumulation and increased confidence in climate change assessments. This advances our understanding of global warming driven by the Earth's energy imbalance.
Scientists have discovered a phenomenon where solid metal bismuth retains structural motifs from its liquid predecessor, even when cooled back to solid. This effect, known as 'structural memory', is correlated with changes in magnetic properties and has potential applications in electrical engineering.
Researchers found that Republicans are less likely to conform to the scientific consensus on global warming when temperatures are extreme, while Democrats are more likely to attribute it to human activity. Temperature anomalies exacerbate existing political polarization and partisan differences over global warming beliefs.
Case Western Reserve University awards Marian Wright Edelman the 2017 Inamori Ethics Prize for her life's work as a fierce advocate for children's rights, poverty alleviation, and access to education. The founder of the Children's Defense Fund has championed policies to protect vulnerable populations and ensure their well-being.
A new research project aims to explore the mechanisms causing earthquakes in the lower crust, accounting for 30% of intracontinental seismic activity. By combining geological and satellite observations with laboratory work, scientists hope to increase knowledge of geological processes and mitigate the dangers posed by such activity.
Researchers at UTHealth aim to increase HPV vaccination rates among minority youth in medically underserved areas by launching a three-year project. The initiative includes a parent-focused social marketing campaign and comprehensive school-based vaccination clinics to educate parents and adolescents about the vaccine's importance.
Researchers discover Fat2 and Lar proteins trigger leading and trailing edge movements during epithelial migration, enabling coordinated tissue movement. This process is crucial for embryonic development, wound healing, and cancer progression.
Researchers found that adding back beneficial bacteria can help end a cycle of unchecked inflammation, suggesting a new treatment for inflammatory bowel disease. The study suggests targeting the inflammation downstream of NLRP12 with anti-inflammatory drugs or feeding specific beneficial bacteria to potentially lead to treatments.
Researchers found that early intervention with two anti-HIV antibodies can induce potent immunity to HIV, allowing the immune system to effectively control the virus. In a study using macaque monkeys, treatment suppressed the virus levels for up to six months and enabled some animals to spontaneously regain control of the virus.
Researchers mapped saltwater intrusion in the Monterey Bay coastline using ERT, providing a cheaper alternative to drilling 'sentinel' wells. The study aims to improve groundwater models and help local water managers make informed decisions about pumping groundwater.
Researchers identified short DNA segments influencing tilapia's internal body chemistry in response to salinity stress, paving the way for targeted studies on gene regulatory networks. This discovery may help enhance stress tolerance in fish, critical for management practices preventing species extinction.
A team of researchers discovered that the parasite Trypanosoma brucei has an internal clock, enabling it to adjust its composition and functions according to the day-night cycle. This finding could lead to more efficient treatment with chronotherapy, a concept already applied in other diseases.
Researchers have created a precise atomic map of the frontline antimalarial drug mefloquine, showing how its structure could be changed to make it more effective. The study provides a route to develop new treatments with fewer resources and potentially reduced side effects.
Researchers at Medical University of South Carolina found that inhibiting moesin reduces numbers of regulatory T cells, enabling the immune system to see and attack cancer. This could lead to new treatments for cancer and Treg-related immune disorders.
Researchers at Columbia University are developing virtual power conversion systems that use interchangeable converter modules and software to control the converter function, reducing size, cost, and increasing reliability. These systems could lead to 20-30% reductions in Volt-Ampere rating for electric vehicle drivetrains.
Researchers found no decline in primary care availability despite the millions of newly insured individuals. Appointment rates and wait times remained stable or increased slightly in some states, supporting the possibility that primary care capacity was sufficient to absorb the new patients.
Researchers found that the original Mona Lisa painting is often seen as happy, and participants identified happy faces more quickly and with greater certainty. The study suggests that our brain has a bias towards positive facial expressions.
A group of researchers recommends increased transparency at the FDA, including disclosure of regulatory information, analysis, and study data. This would enhance understanding of existing therapies, pharmaceutical pipelines, and innovative product development.
A research group has developed a sweat-based glucose monitoring and maintenance device that allows rapid glucose measurement and precise multistep drug delivery. The system features a disposable strip sensor, enables precise and timely drug delivery, and offers a painless blood glucose monitoring method to control blood glucose levels.
Scientists at Ecole Polytechnique Fédérale de Lausanne are developing intelligent neuroprosthetics that can decode brain signals and stimulate spinal cord muscles to facilitate walking movements. Clinical trials are currently underway to test the feasibility of these devices on patients with partial paralysis.
A study by Aarhus University found that longer deadlines increase charitable donations. The researchers sent emails and text messages with varying deadlines to approximately 53,000 Danes who had previously donated money. As a result, the donations increased when the deadline was longer.
Research suggests that temporary episodes of dizziness upon standing may cause lasting damage to the brain, increasing the risk of cognitive decline and dementia. Middle-aged individuals with orthostatic hypotension were 40% more likely to develop dementia than those without it.
Researchers at Georgia Tech have developed a nanofiber catalyst that improves the efficiency of rechargeable batteries and hydrogen production. The new catalyst, made from double perovskite nanofibers, shows significantly enhanced oxygen evolution reaction capability compared to existing materials.
Tropical Cyclone 11S has been stretched out due to moderate vertical wind shear, according to NASA satellite imagery. The Joint Typhoon Warning Center expects the storm to strengthen before encountering stronger wind shear and cooler sea surface temperatures.
Operation IceBridge's ninth year in the Arctic will be its most extensive campaign yet, with two new research flights based out of Svalbard to survey the Eurasian sector. The mission aims to collect valuable data on polar ice changes and improve snowfall accumulation models.
Researchers have developed more realistic 3-D co-culture models of intestinal tissue, incorporating immune cells like macrophages, to study Salmonella infections. The models better recapitulate the natural infection process and offer a powerful new tool for understanding enteric pathogenesis.
A team of researchers has identified a gene that causes Opitz C syndrome in the only patient diagnosed with this ultra-rare disorder in Catalonia. The study used DNA massive sequencing techniques to identify the altered genes in each patient, providing new insights into the genetic basis of this disease.
The updated guidelines focus on global risk assessments and non-invasive testing results, emphasizing individualized case evaluation. The revised criteria aim to improve quality of care by delivering the right treatment to the right patients.
Scientists at Lomonosov Moscow State University developed a new approach to monitor environmental status in Moscow, using gas chromatography-mass spectrometry analysis. The method detects novel pollutants and expands the list of hazardous substances, posing potential threats to human health and ecosystems.
A new study proposes 'agrowth' as a middle ground between pro-growth and anti-growth policies, aiming to reduce resistance to climate policies. The research suggests that adaptation to climate change can be achieved through flexible economic strategies, rather than relying solely on growth.
A new study by Kristian Berg and Mark Aronoff found that English suffix patterns can categorize words into grammatical categories, such as adjectives. The researchers analyzed a large sample of written English documents over 1,000 years, discovering consistent spellings for common suffixes like -ous and -ic.
A study published in Scientific Reports found that water temperatures generally remain low despite rising air temperatures, helping to curb greenhouse gas emissions. The research, conducted by Uppsala University, involved nearly 3,500 schoolchildren taking measurements and samples from lakes across Sweden.
Researchers at Peter the Great St. Petersburg Polytechnic University and Delft University of Technology created a technology for obtaining gradient microstructures in metals, combining properties of two metals for high performance characteristics.
University-based startups can benefit from university-funded seed capital programs, which provide expanded funding opportunities, entrepreneur development, and economic growth. These programs also help faculty members and students develop their entrepreneurial skills and support the commercialization of innovative technologies.
A Mayo Clinic study found that high-intensity aerobic exercise can reverse cellular aspects of aging, improving lean body mass and insulin sensitivity. The study also showed that high-intensity interval training enhanced muscle protein content, causing muscle enlargement and improving energetic functions.
The National Academy of Inventors conference highlights the importance of creating innovation ecosystems and overcoming biases against women in science. The issue also explores the role of technology transfer in universities and its potential to benefit society.
Earl Smith's research seeks to determine how visual experience affects refractive development and explore new pharmaceutical approaches to eliminate myopia. The goal is to slow the progression of nearsightedness in children, addressing a growing global epidemic that affects over two billion people.
Researchers have characterized cerebral organoids, showing they recapitulate human brain developmental processes and involve forebrain organizing centers. These findings advance our understanding of normal organoid development and are essential for modeling human developmental diseases.
Tropical Depression Enawo strengthened off Madagascar before being weakened by wind shear, according to NASA's Terra satellite imagery.
A new UBC study examines the environmental and socioeconomic performance of organic farming, finding that its benefits are context-dependent. Organic farming's yield is often lower than conventional methods, but it has an important role to play in promoting sustainable agriculture.
Researchers discovered a new iron arsenide superconductor, CaKFe4As4, with a high superconducting temperature of 35K without dopants, questioning established theories. The material's pristine samples allowed for accurate measurements of the superconducting gap, contradicting previous models.