A team of researchers from Osaka University has developed new methods for proliferating and breeding drought-resistant jojoba. These innovations enable the efficient production of high-quality clones and genetic transformations using agrobacterium, resulting in improved screening indices.
Researchers at Alliance for Cancer Gene Therapy (ACGT) have received $1.3 million in critical funding to study immunotherapy and virotherapy for three deadly forms of cancer: glioblastoma, sarcoma, and ovarian cancer. The grants will support clinical trials to test innovative treatments using gene therapy.
Researchers developed a plan to eliminate unnecessary medical testing by providing educational efforts, auditing testing patterns, and harnessing electronic medical records. This initiative aims to reduce medical bills while improving patient outcomes, safety, and satisfaction.
Researchers will investigate brain aging and Alzheimer's using advanced bio imaging technology on a representative sample of 1,310 Tsimane adults. The project aims to understand the relationship between vascular health and Alzheimer's risk.
A team of researchers used stem cell technology to generate motor neurons from ALS patients with FUS mutations, revealing axonal transport defects. Genetic correction and pharmacological inhibition of HDAC6 restored axonal transport, suggesting a potential therapeutic approach for ALS.
Scientists successfully read several bytes of data stored on a molecular scale using synthetic polymers, setting a new benchmark for data storage. The breakthrough enables the use of polymers in hard drives to reduce size by 100 times.
Scientists at University of Bristol develop new approach to monitor early stages of electrodeposition with nanometer resolution. By detecting subtle changes in water structure, they can track the formation of a metallic nucleus in real time.
A study in rural China found that healthcare providers fail to correctly manage tuberculosis cases, with a high proportion of antibiotics prescribed unrelated to TB treatment. The researchers highlight the need for reforms and improved training to address these gaps in care.
Researchers found that wolves excelled in cooperative behavior compared to dogs, even when raised together under similar conditions. The study suggests that domestication may not have increased tolerance and cooperation among dogs as expected.
Tropical Storm Lan is intensifying as it moves through the Northwestern Pacific Ocean, fueled by extremely high oceanic heat content. NASA's Aqua satellite data shows storm clouds with cloud top temperatures reaching minus 63 degrees Fahrenheit, capable of producing heavy rainfall.
Researchers found a significant association between elevated systolic blood pressure and the development of mitral regurgitation, a condition where the heart valve leaks. The study suggests that controlling blood pressure may be crucial in preventing this common heart valve disorder.
A new systematic review of evidence suggests that primary care physicians and their teams can provide effective addiction care using anti-opioid medication. The studies found that patients had the highest chance of successful treatment when working with a team of non-physicians, including nurse case managers.
A recent study has found that tropical high-altitude beetles are at risk of extinction due to climate change. The research, conducted in the Brazilian Atlantic Rainforest, revealed that two plant-eating beetle groups - weevils and leaf beetles - are highly specialised to high altitudes and may disappear in a warmer world.
A new gene expression profiling assay has been developed to enhance the diagnosis and treatment of non-Hodgkin lymphoma, particularly diffuse large B-cell lymphoma. The assay can differentiate between three major subtypes associated with different outcomes, including germinal center B-cell-like and activated B-cell-like subtypes.
The Translational Genomics Research Institute has developed novel processing methods for single-cell RNA sequencing, enabling researchers to identify genetic sources of diseases and tailor treatments. This breakthrough is crucial for understanding cancer and improving patient care.
A new study by University of Maryland School Medicine researchers found that nearly half of all US medical care is delivered by emergency departments. Emergency department visits increased by 44% over a 14-year period, with African-American patients and those without insurance using these services at a higher rate.
A new study from Linköping University finds that corticosteroids can improve tendon healing if administered at the correct timing. The research reveals that inflammation must subside before new tissue formation begins. When given after the early inflammatory phase, corticosteroids significantly enhance tendon strength in rats.
The AMOEBA force field provides a detailed understanding of protein-ion interactions by incorporating quantum methods. The model distinguishes selective ion binding in calcium and magnesium ions, shedding light on their role in various biological processes.
A researcher from MSU has discovered complex changes in temperature and relative humidity in Moscow over the past century. Urban heat island intensity stabilized in the second half of the 20th century but increased in recent years due to urban densification.
A UK-wide PrEP programme would be cost-effective, preventing up to one in four HIV cases. The study estimates savings of up to £1 billion over 80 years as a result of fewer men needing lifelong HIV treatment.
Researchers at the Francis Crick Institute have identified a novel protein that exclusively targets Wnt signalling in tumour cells, reducing growth of colon cancer cells without harming healthy cells.
Researchers at UAB discovered that overexpressing a cell-cycle activator gene CCND2 increases the proliferation of grafted cardiomyocytes, leading to improved cardiac function and reduced infarct size. This breakthrough may pave the way for future clinical treatment of human heart attack patients.
Researchers created a computational model to improve the efficiency of CRISPR-Cas9 genome editing by allowing off-target cuts, which may help on-target cutting be faster. The model suggests that proteins can correct mistakes and tolerate minor mutations, potentially leading to more precise gene editing.
A new study from The George Institute for Global Health at the University of Oxford found a strong link between high blood pressure and mitral regurgitation, a condition that makes the heart less efficient at pumping blood. Lowering blood pressure through exercise, diet or medication may reduce the risk of developing this condition.
Researchers developed a wearable device called VAuth that creates a unique and secure signature using speech-induced vibrations on the user's body. The technology has achieved a 97-percent detection accuracy and successfully thwarts various practical attacks, making it a promising solution to enhance voice authentication security.
Researchers have discovered that a specific microbe can oxidize and metabolize metals from synthetic Martian regolith simulants, leaving behind unique signatures. This finding could enable the extraction of metals from asteroids and other celestial bodies using biological methods.
The American Federation for Aging Research (AFAR) has awarded $800,000 to seven junior faculty members to support their research on healthy aging and age-related diseases. The grants will provide flexible funding for one- to two-years to advance knowledge of the aging process and its associated diseases.
A new set of breathing techniques, developed by Dr. J Tod Olin, has been shown to effectively treat symptoms of EILO in athletes. The techniques, which include the tongue variant, tooth variant, and lip variant, help athletes open their obstructed airways during high-intensity exercise.
Scientists at Tel Aviv University utilize Nobel-winning research to detect gravitational waves produced by the merger of two ancient neutron stars. This discovery combines gravitational waves with light, producing a detailed model of the emission for the first time.
A new study published in PLOS ONE found that male attendees asked 80% more questions than female attendees at a large international conference. The researchers suggest that this disparity may be linked to gender inequality and stereotypes affecting women's confidence to speak publicly.
A BYU study with mice reveals stress can alter gut microbiota to resemble a high-fat diet, potentially contributing to gender-specific health disparities. Researchers found distinct changes in female mice's digestive microorganisms upon exposure to stress.
A 10 pence levy on sugar sweetened drinks at UK-based Jamie's Italian led to a 9-11% decrease in sales, with the impact greatest in restaurants with highest pre-existing sales of these beverages.
During a crisis, people are exposed to conflicting information and stress. Those relying on social media report greater rumor generation and distress. UCI-led research found that communications vacuums can lead to rumor transmission and increased community-level negative emotion.
A study in Belize found that herpetofaunal communities remained relatively unchanged after Hurricane Earl, despite significant changes in the environment. The research highlights the ability of these species to adapt to anthropogenic pressures.
Researchers observe historic detection of neutron star merger in both gravitational waves and the entire spectrum of light, offering insights into a cosmic event. The merger, named GW170817, revealed properties of the dense neutron stars and their collision, providing new opportunities for gravitational testing.
A recent study by Philipp Mitteroecker and colleagues used the cliff edge model to predict that women born by Caesarean are more likely to develop FPD in their own childbirth, with a 2.8 times higher risk compared to women born vaginally.
A study published in the Journal of the American Osteopathic Association found that nearly 55% of medical students are confident in their ability to counsel patients on nutritional recommendations, despite half failing a nutrition quiz. The study highlights a gap between nutritional knowledge and attitudes among future physicians.
A team of Australian researchers has confirmed the detection of radio waves from a gravitational wave event, providing new insights into massive bodies like black holes. The discovery was made using the CSIRO's Australia Telescope Compact Array and marks a significant contribution to the global discovery of gravitational waves.
Researchers found that water with different isotopes exhibits complex dynamic properties when in contact with liquid water. The team's findings have significant implications for understanding ice crystallization and its applications in various industries, including agriculture and food preservation.
A study by the American College of Physicians found that almost 11 million US men have oral human papillomavirus (HPV) infection, with a high prevalence among men with multiple lifetime oral sex partners and those who report having sex with men. HPV causes various cancers, including oropharyngeal squamous cell carcinoma, which dispropo...
Researchers confirm neutron star collision using electromagnetic radiation detected by NASA's Swift Gamma Ray Burst Explorer. The event provided a complete picture of compact object mergers, marking a major breakthrough in astronomy.
A Science DMZ architecture can be adapted to meet the needs of the medical research community, allowing for secure sharing of large datasets while protecting individual privacy. The design provides speed and security for moving large data sets, enabling teams of experts to collaborate in real-time.
The American College of Physicians urges physicians to make a public commitment to talk to their patients about firearms and counsel them on safe firearm behaviors. Physicians who commit to this action can find resources and information in the growing literature.
Researchers at LMU's Gene Center found that human cells use a different mechanism to recognize misplaced DNA than mouse cells. The inflammasome complex is activated via the cGAS-STING recognition mechanism, triggering both an antiviral response and a classical inflammatory reaction.
The team used the Swope telescope to discover the light produced by the merger and obtained the earliest spectra of the collision. These observations may allow scientists to explain how many of the universe's heavy elements were created.
UCSB astronomers capture the fleeting kilonova using a network of telescopes and gravitational wave data. The event sheds light on the formation of heavy elements in the universe.
A Kansas State University researcher has documented that American alligators on the Atlantic and Gulf coasts are consuming small sharks and stingrays, a widespread interaction previously unreported. The study reveals that alligators seek out freshwater habitats with high salinity to prolong their time in saltwater environments.
Tandon researcher Jin Montclare develops phosphotriesterase (PTE) variants to neutralize toxic chemical agents, including VX and organophosphorus compounds. Her goal is to create stable, robust, and effective antidotes with improved therapeutic efficacy.
A new study sheds light on the molecular mechanism that shapes behavior in fruit flies, revealing a causal link between epigenetics and genetics. Researchers found that epigenetic marks interact with genes to regulate differences in feeding behaviors.
A research team led by Dr. Claudia Barros aims to understand the cellular changes leading to glioblastoma brain tumor development. Using a Drosophila fruit fly model, they visualize cancer stem cells and identify early molecular changes.
Third-year physics graduate students Kaitlin Rasmussen and Devin Whitten witnessed the historic event using the 2.5-meter Irénée du Pont Telescope in Chile. The observation provided valuable insights into the rapid-neutron capture process, a key mechanism for forming heavy metals like gold, platinum, and uranium.
A study of African-American and Latino adults in a high-risk urban community found that despite numerous risk factors, the rate of substance use problems is low for a substantial proportion of participants. Protective 'resilience' factors, such as support, education, and employment, also play a crucial role in preventing substance misuse.
A new study by the University of Exeter found thousands of social media accounts celebrating extreme thinness, featuring selfies with protruding bones. The research suggests that these platforms are encouraging eating disorders and promoting unhealthy body image among young women.
A commercial weight management program delivered by Weight Watchers helped more than half of patients at risk of developing type 2 diabetes to reduce their risk or get their blood sugar levels back to normal. The program led to significant reductions in diabetes risk, with an average fall in HbA1c levels and notable weight loss.
Researchers at University of Sussex and Swansea University have created a way to morph liquid metal into physical shapes, opening up new possibilities in soft robotics and shape-changing displays. The invention uses electrical charges to program the liquid metal, allowing it to dynamically change shape and form complex geometries.
A new study reveals that cancer cells can use the body's own immune system to wake themselves up and fuel their growth after treatment, leading to relapse. Researchers found that immunotherapies targeting this response could delay or prevent cancer return in mice, suggesting a promising approach for patients at risk of relapse.
Scientists are learning how too little body fat damages the cardiovascular system, similar to obesity. Leptin replacement therapy shows promise in reducing cardiovascular risk and improving metabolic function in individuals with congenital lipodystrophy and other conditions.
The nursing workforce is becoming increasingly diverse and educated, with a significant increase in male nurses and those from underrepresented ethnic groups. The study also shows improvement in working relationships between nurses and physicians, with a notable increase in collaborative teams across disciplines.
Researchers discover how seizures trigger cognitive deficits in Alzheimer's disease through increased levels of the protein deltaFosB, leading to suppressed production of calbindin and disrupted brain activity. Further studies support the findings, showing potential new strategies for reducing cognitive deficits.
Mousensor, LLC has been awarded a National Science Foundation Small Business Innovation Research (SBIR) grant to develop a human-nose-on-a-chip based on fundamental research at CUNY. The company aims to detect and digitize every single smell, enabling fragrance houses to increase competitive advantage through unique product development.