Treg cells suppress immune function, but eliminating them doesn't eliminate their effects. In fact, dying Tregs release metabolites that affect T-cells, making them unhealthy and reducing the cancer-fighting effect of immunotherapy. The study suggests a new approach to limit this function and block the suppressive activity.
Researchers at Michigan State University have identified key genes that helped domesticated potatoes adapt over thousands of years. By studying the ancestors of modern North American cultivated potatoes, scientists uncovered common genes and important pathways that enabled spuds to thrive in diverse environments.
A phase two trial showed improved motor function in children with spastic cerebral palsy who received an infusion of their own umbilical cord blood cells. The improvements were greater than those seen in children receiving lower doses or a placebo, and exceeded expected gains from traditional therapies.
A new open-source machine learning program at Georgia Tech predicts cancer drug effectiveness via genetic data, reducing human bias and increasing accuracy. The program aims to be widely used by researchers to improve treatment outcomes.
A study published in the Journal of the American Osteopathic Association found that group exercise significantly improved mental, physical, and emotional quality of life, with a 26% reduction in stress levels. In contrast, individual workouts had no significant impact on stress levels or quality of life.
Researchers have discovered a way to visualize tiny vibrational resonances using quantum dots, which could lead to the development of new sensing technologies. The technique uses light waves to drive the motion of a thin membrane, creating patterns that can be visualized through an array of quantum dots.
Researchers have produced a 3D map of SgK223, a molecular scaffold that plays a critical role in the development and spread of aggressive breast, colon, and pancreatic cancers. The map will enable targeting of specific regions critical for its function, potentially leading to novel strategies for cancer treatment.
Pregnant women who consume high-dose omega-3 fatty acids daily during the 3rd trimester are less likely to develop asthma in their children. Researchers recommend 8-12 ounces of low mercury fish per week for similar benefits.
Extra-Tropical Storm Saola transitioned from a tropical storm and tracked southeast of Japan, moving north of Hokkaido on October 30. The storm was east of Japan's northern island of Hokkaido, with clouds stretching into the Sea of Okhotsk and northwest Pacific Ocean.
Two Princeton astrophysicists have received funding to investigate the physics of merging neutron stars, which produce heavy elements found in our bodies. The project aims to improve our understanding of these events and their observable signatures.
Patients with left main coronary artery disease (LMCAD) who underwent percutaneous coronary intervention (PCI) or coronary artery bypass graft surgery (CABG) showed similar quality of life improvements at three years. PCI demonstrated a greater early benefit, with improved health status measures that were sustained over time.
The Lancet Countdown report reveals that climate change is having a significant impact on health, with 125 million adults over 65 exposed to heatwaves, and an estimated 5.3% loss in labour productivity. The report also highlights the increase in mosquito-borne diseases, air pollution, and economic losses linked to extreme weather events.
A team of scientists has captured the time delay between X-ray flares and optical light flashes in a stellar-mass black hole, resolving controversy over jet plasma activation. This study uses precise multi-wavelength observations to demonstrate that relativistic jets are formed by gravity and magnetic fields.
A large Canadian study links e-cigarette use among high school students to later cigarette smoking. The study found that youth who used e-cigarettes were more likely to start and continue smoking cigarettes. However, the association may be due to common factors rather than a causal effect.
A new study found that smokers who received financial incentives, in addition to personalized support, were nearly 10 times more likely to quit smoking after six months compared to those in the control group. The intervention also showed significant reductions in smoking rates among older participants, women, and non-white smokers.
A team of researchers used the Subaru Telescope to study Messier 77, revealing evidence of a hidden minor merger billions of years ago. The discovery provides crucial evidence for the minor merger origin of active galactic nuclei and sheds light on the mysterious phenomenon.
A new $9 million study will compare two approaches to relieving noncancer chronic pain and reducing opioid use. The study will assess which approach leads to lower or discontinued opioid use and greater pain relief among people who have been using opioids over the long term.
Researchers found that migratory birds prefer fields with cover crops like cereal rye, providing a safe area to escape predators and increasing insect abundance. This leads to improved bird habitat and increased fueling time for migrants.
A new study from Scripps Research Institute reveals that egg-based production causes the virus to target bird cells, disrupting the major antibody target site on the surface. This mutation renders the flu vaccine less effective in humans, with recent vaccines proving only 33% effective against H3N2 viruses.
A new study reveals that America's power supply might be more adaptable to climate change due to maintenance and efficient energy technology. However, further research is needed to understand the collective strengths and vulnerabilities of the US power grid under climate conditions.
Research using ESA's XMM-Newton and NASA's Chandra X-ray observatories found that Jupiter's south pole X-ray emissions pulse every 11 minutes, while north pole emissions are erratic. This behavior is distinct from Earth's auroras, which mirror each other in activity.
A Loyola Medicine sports medicine physician warns that even perfectly executed dives can lead to injuries, with a focus on back, shoulder, and elbow injuries. The athlete's intense training schedule, including frequent dry-land exercises, also contributes to the risk of injury.
Researchers analyzed nasal morphologies to infer Neanderthal soft tissue, finding that cold-adapted nasal configurations evolved independently in both species. Computational fluid dynamics simulations showed faster air warming and humidification rates in Neanderthals compared to modern humans.
Researchers at Binghamton University have developed a new type of microphone that uses spider silk to improve directional sensing across a wide range of frequencies. The study, led by Professor Ron Miles and graduate student Jian Zhou, found that the fine fibers are able to pick up velocity rather than pressure of air waves.
A new study found that precision medicine for oncology is less precise for people of Latin American, African, and Asian ancestry due to the lack of diverse genetic population data. A computational tool called LumosVar was created to help researchers sort out potentially inaccurate results and improve precision medicine.
Climate change and human activities are putting North Atlantic right whales under immense pressure, with food scarcity and high mortality rates exacerbating their decline. The study predicts population growth will be hindered by climate-mediated food availability and policy-driven mortalities.
Researchers at Brookhaven National Laboratory developed a method to reduce surface reflections from glass surfaces to nearly zero by etching tiny nanoscale features into them. This achievement could enhance solar cell efficiency, improve electronic display use, and support high-power laser applications.
New research published in Epilepsia indicates that wristband devices can improve the detection and characterization of seizures in patients with epilepsy. The devices detected 95% of seizures while keeping false alarm rates at a bearable level, providing real-time alerts to caregivers and improving patients' quality of life.
Research by Anglia Ruskin University shows that right-handed baseball players who bat left but throw right-handed have a surprising advantage in career success and hitting performance. This biomechanical advantage provides a longer lever to hit the ball, increasing their chances of becoming top hitters.
Researchers have created artificial codes to regulate viral assembly, outperforming natural codes in efficiency. The new understanding of viral self-assembly codes could lead to breakthroughs in cancer therapy and immunization.
A genetic study of dingoes found the species likely migrated to Australia in two separate waves via a former land bridge with Papua New Guinea. The study recommends treating genetically distinct populations as different groups for management and conservation purposes.
Researchers at the University of Arizona found that even with perfect natural selection, aging would still occur due to cancer cells cheating the system. Slowing down one type of cell can lead to an increase in another problematic cell type, making it mathematically impossible to halt aging.
The University of Illinois Chicago has launched the 3/40 Blueprint website to address the lack of systematic research on LGBTQ youth homelessness. The site provides a user-friendly platform for professionals to access concise reports and original research, aiming to facilitate smooth transitions for these vulnerable youth.
Researchers at Columbia University's Mailman School of Public Health found a significant increase in depression among Americans aged 12 and older from 2005 to 2015. The prevalence of past-year depression rose from 6.6% to 7.3%, with the most rapid increases seen in young people and those with lower levels of income and education.
Post-tropical Cyclone Selma dissipated near the border of El Salvador and Honduras as its maximum sustained winds decreased to near 30 mph. The cyclone's estimated minimum central pressure was 1007 millibars, with weakening continuing until it dissipates over the Sierra Madre Mountains.
Sandia engineers have designed a control system that doubles the power absorbed by wave energy converters, making electricity produced from wave energy less expensive. The team applied robotics and aerospace engineering design principles to refine how a wave energy converter moves and responds in the ocean.
A new study suggests that climate change will negatively impact the reliability of US electricity generation, but today's infrastructure can be adapted to future conditions. Improvements in resiliency are driven by policy and economic opportunities making US power supply cleaner and more efficient.
Research shows long-term aspirin use significantly reduces digestive cancer incidence, with substantial reductions in liver and oesophageal cancers. Aspirin use also shows promise in reducing risk of certain other cancers, while raising cardiovascular risk when stopped.
A new study by Rice University found that nearly a quarter of Mexican immigrants living near the California-Mexico border without legal authorization have a mental disorder, with major depressive disorder, panic disorder, and generalized anxiety disorder being the most prevalent. The study's findings highlight the need for culturally s...
A new study by researchers at the University of Oklahoma and Oklahoma State University found that individual perceptions of climate anomalies are largely immune to political bias. The study used high-resolution data and address-based panel survey to examine how people in Oklahoma perceived climate anomalies, including extremes of tempe...
Scientists have developed a theory explaining how animals adjust their movement patterns in response to environmental cues such as food, predators and mating partners. The research reveals the complex interplay between an animal's force, drag, and behavioral response to environmental signals.
Garry Sunter, a UTSA researcher, has received a $1 million award to develop an insect-based technology that delivers genetic therapies to improve the health of mature, vulnerable plants. The goal is to enable plants to thrive in challenging conditions such as drought and disease.
Researchers demonstrated that nanotwins in metal's atomic lattice stabilize defects associated with repetitive strain, limiting accumulation of fatigue-related damage. This work shows a promising approach to creating more fatigue-resistant metals.
A study suggests that massive boulders in the Bahamas were transported by hurricanes during the Last Interglacial period, increasing risk of erosion with rising sea levels. The research highlights the potential impact of climate change on coastal environments.
Research found that multiple adverse experiences in early childhood are linked to depression and physical health problems in kids as young as 9-15. The study identified a potential pathway in the brain that explains how stressful experiences influence poor health.
A small pilot study found that focused ultrasound treatment improved hand tremor by up to 62% in participants with Parkinson's disease, with minimal side effects. Further research is needed to confirm the effectiveness and potential role of this scalpel-free surgery approach.
A new report highlights the need for sustainable solutions to address growing energy demands from emerging middle classes. The study finds that adoption rates of energy-efficient materials and technologies vary greatly across countries due to differences in climate, economic power, and public perception on climate change.
A clinical trial involving 311 patients with prodromal Alzheimer's found significant advantages in nutrient-treated patients, including 45% less worsening in Clinical Dementia Rating-Sum of Box. The study also showed less brain atrophy in the active group, with notable benefits for hippocampal damage and everyday tasks.
A new study found that 89% of Hispanic women and 81% of non-Hispanic white women use herbal remedies. However, only a third of white women and less than 1 in 6 Hispanic women discuss their use of herbal treatments with doctors.
The UA Cancer Center research team has discovered that genistein, a compound found in soy foods, can protect BRCA1, a gene crucial in thwarting tumor development in breast tissue. This finding offers new hope for treating triple-negative breast cancers, which currently have no targeted chemotherapy available.
University of Delaware researchers have developed catalysts that transform lignocellulosic biomass into high-carbon molecules suitable for jet fuel, enabling cost-competitive and sustainable production. The process operates at low temperature and is scalable, addressing the need for non-petroleum-based fuels for aviation.
A recent study found that participants with type 2 diabetes who lost weight through lifestyle changes had better blood flow to the brain, suggesting a potential cognitive benefit. The intervention was most effective for individuals who were overweight but not obese.
A new report by digital learning experts recommends following promising strategies to address equity in learning technologies. These include unifying around shared purpose, aligning home, school, and community, connecting to minority youth interests, and targeting specific subgroup needs.
Researchers at the University of Sydney have discovered unique micro-RNA molecules in the blood that can diagnose multiple sclerosis (MS) and predict its progression. These findings hold promise for developing a definitive diagnostic test, which could lead to earlier treatment and improved outcomes for people with MS.
A study found that captive bears fed a diet high in saturated fats and low in polyunsaturated fats did not develop insulin resistance or other diseases. However, mild inflammation and heart strain were observed, raising concerns about the long-term health of bears in the wild that feed on human refuse.
A recent study by Maastricht University Medical Center and Maastricht University found that a specific enzyme, NOX4, plays a crucial role in the brain's sensitivity to hypoxia. This discovery has significant implications for treating post-stroke brain damage.
Jens Nielsen's groundbreaking work in systems biology and engineering has earned him a gold medal from the Royal Swedish Academy of Sciences. His research focuses on developing efficient cell factories for sustainable production of fuels and chemicals, with implications for a more sustainable lifestyle.
A nationwide review found that only 47% of patients were approved for PCSK9 inhibitor therapy, with the highest approval rates for Medicare and lowest for private insurance. The study suggests that better education and uniform guidelines are needed to reduce administrative waste.
Tropical Depression 18 strengthened into Tropical Storm Philippe, located off Florida's east coast on Oct. 29, according to NASA's Aqua satellite analysis. The storm's cold cloud tops indicate very heavy rainfall potential.
Chinese researchers found that nano-diamond significantly enhances the performance of magnetorheological fluids (MRFs), increasing their shear yield strength and settling stability. The results show a high potential for MRFs to be highly enhanced through the process, with improved settling stability under different magnetic fields.