A comparative clinical trial found that delivering corticosteroids directly into the eye is more effective than injecting them adjacent to the eye in treating uveitic macular edema. The treatment led to significant reductions in macular edema and improvements in visual acuity, with intravitreal triamcinolone and dexamethasone implant s...
Researchers found that exercise stimulates autophagy, a cellular process responsible for removing damaged proteins and toxins from muscles. The study shows that regular physical activity can reduce the buildup of toxic proteins in muscles, leading to improved muscle function and reduced wasting.
Researchers have demonstrated that noise can induce coherence resonance in nonlinear systems, allowing for the detection of weak signals without a reference signal. The results show promise for developing passive lock-in amplifiers with reduced integration times and operating range.
The University of Freiburg has been granted two Clusters of Excellence, CIBSS and livMatS, with funding of up to 100 million euros over seven years. The clusters will focus on biological signalling studies and bioinspired materials research.
Researchers have developed a novel method to assess the quality of iron oxide samples, enabling them to understand their effects on patient safety. By combining gamma ray spectroscopy with 'center of gravity' analysis, scientists can quantify diffusive oxidation processes and track changes over time.
A new study published in the journal Science reveals that killer whale populations are severely affected by PCBs, with over half of studied populations showing significant declines. The research predicts that these populations may disappear within 30-50 years if current levels of pollution persist.
A new course at Boston University School of Medicine aims to educate students and trainees on machine learning concepts, preparing them for the growing data science revolution in healthcare. The authors emphasize the need for embedding ML curriculum into medical education to enhance clinical decision-making and management.
New research reveals that Rnf212 helps create a 'cellular memory' of DNA damage in oocytes, allowing cells to assess the severity of defects and prevent defective eggs from being formed. This process ensures that only high-quality eggs are selected for the ovarian reserve.
Researchers found intravitreal treatments to be superior to periocular injections in reducing macular edema and improving visual acuity. The study suggests shifting towards intravitreal corticosteroid injections for treating uveitic macular edema.
Some species are unable to recognize genetic differences between their own offspring and those of intruders, leading to acceptance. Genetic features associated with recognition may have died out due to the disadvantage of being different, making it impossible for parents to reject parasitic offspring.
Researchers at Cornell University have developed a new test that employs a bacteriophage to detect the presence of E. coli in drinking water. The test can provide results within hours, rather than days, allowing for faster action to be taken in case of contamination.
Researchers at Duke University have developed a new technique to reconstruct sequence of diffuse images from one long photographic exposure. By using a coded aperture, they can extract individual frames from a single, scattered exposure, overcoming limitations such as motion and constant scattering medium.
A study by Mohammad Asghar seeks to understand age-related kidney function impairment and identify targets for drug interventions. The researcher believes that mitochondrial respiration plays a critical role in maintaining normal kidney function.
A unique source of stem cells in blood helps build blood vessels in embryos, contradicting previous theories. This finding brings scientists closer to using stem cells to repair damaged blood vessels and treat heart and circulatory diseases.
Researchers found gallium effective in curbing bacterial growth in mice and patients with cystic fibrosis or chronic lung infections, including those infected with Pseudomonas aeruginosa. Gallium's slow development of resistance makes it a potential alternative to standard antibiotics.
University of Pittsburgh professors Samuel Dickerson and Renee Clark are using computer-aided simulations to promote reflective and metacognitive thinking among engineering students. They aim to improve learning and development by encouraging frequent use of reflection and metacognition.
Researchers from the University of Cambridge are launching a new clinical trial for a trivalent vaccine targeting Ebola, Lassa, and Marburg viruses. The vaccine builds on nearly two decades of research and aims to predict future outbreaks by studying natural animal reservoirs.
Researchers found that autologous fecal microbiota transplantation (auto-FMT) restored beneficial gut bacteria to near baseline levels within days, mitigating the effects of intense antibiotic treatment. This approach may prove a simple way to quickly restore a healthy microbiome following intensive antimicrobial therapy.
The study reveals a new approach to assess compounds' bioactivity by identifying invariant signatures, enabling straightforward prediction of therapeutic applications and toxicity. This innovation has important ramifications for drug development, selection of safe drug candidates, and repurposing of existing drugs.
Dr Alison Feder's innovative work on HIV's high mutation rates and large population sizes has been recognized with the inaugural Milner Prize. Her research explores how drug resistance evolution affects patient dynamics, shedding light on the complex interactions between viruses and their hosts.
Bees exhibit unique behavior when exposed to external loads, such as wind and rain. By analyzing their responses, researchers have gained insight into the collective problem-solving mechanisms of living systems.
Researchers discovered a new fossil that shows large angiosperm trees grew in North America by the Turonian age, dating back nearly 15 million years earlier than previously thought. This find provides more detail to our understanding of the landscape during this period and sheds light on the evolution of flowering plants.
Tropical Depression 29W has been issued a warning by the Joint Typhoon Warning Center, located near Iwo To off Japan's eastern coast. The storm is expected to strengthen but become extratropical in 24 hours, posing no immediate threat to land masses.
A UCSF-led study found that wearable cardioverter defibrillators lower mortality among patients who wear them consistently, but do not significantly reduce sudden cardiac death. The devices were more effective in reducing overall mortality, with a 35.5% lower risk of death compared to those who did not wear the device.
A Baltimore study found that liquor stores have a stronger association with violent crimes, including homicides and aggravated assaults, compared to bars and restaurants. The researchers found that low-income neighborhoods have higher access to liquor stores and beer wine stores, which are linked to increased violence
Researchers found that DEET interferes with Caenorhabditis elegans' neural circuitry, jumbling their response to certain odors. This knowledge could help develop more effective DEET alternatives.
A new study found that teenagers exposed to TV and film violence and high levels of household conflict are at risk of engaging in aggressive behaviors. Parental monitoring is a strong protective factor against aggression, even when combined with other risk factors.
The study uses tiny gravitational distortions to measure the lumpiness of dark matter in the universe. The researchers find that the new observations are consistent with the simplest model for dark energy, but more data are needed to confirm the results.
Researchers developed a new spectro-gonio radiometer called SHADOWS to analyze light reflected from very small or extremely dark materials. The instrument can probe samples measuring less than one millimeter cubed and provide information on physical and chemical properties.
The Human BioMolecular Atlas Program (HuBMAP) aims to create a 3D map of the human body showcasing how tissues differ on a cellular level. This will provide scientists with a deeper understanding of tissue organization, growth, and function, ultimately leading to disease prevention.
Researchers create spheres that can be made at low cost and promise to mitigate the energy-intensive techniques now used to make cement. The spheres are suitable for various applications, including bone-tissue engineering, insulation, ceramic, and composite materials.
Researchers analyzed 8.9 billion tweets to track the origin and spread of new words in American English, revealing 5 key regions: West Coast, Northeast, Mid Atlantic, Deep South, and Gulf Coast. African American English was a major source of lexical innovation.
Research suggests that breastfeeding can change gene activity in infants, making them less reactive to stress. The study found that breastfed babies had decreased DNA methylation and cortisol reactivity.
Researchers at the University of Sydney have developed a chip-based technique that uses acoustic noise to increase signal capacity and processing speed in local networks. The new technology harnesses stimulated Brillouin scattering to extract and regenerate electronic signals, promising to reduce latency in high-speed services such as ...
A large study published by The BMJ found that newer combined oral contraceptives are associated with a reduced risk of ovarian cancer in young women. The positive effect strengthens with longer periods of use and persists for several years after stopping, providing reassurance for women.
According to a study by Rice University data scientists, the number of groups and organizations an individual joins is crucial in forming online friendships. The researchers found that individuals who are active in multiple communities have a higher chance of meeting people with similar interests.
Scientists at NIST and Maryland State Police Forensic Sciences Division developed a protocol to measure background drug levels, which can affect test results. The study found detectable amounts of 13 substances, including fentanyl, on various surfaces, highlighting the need for regular cleaning and increased sensitivity in labs.
Researchers at Osaka University developed a new method to efficiently heat plasma using high magnetic fields and relativistic electron beams. By guiding the beam along magnetic field lines, they achieved higher energy coupling rates than previous methods, making this approach more suitable for controlled nuclear fusion.
Scientists have solved the structure of two proteins that control DNA packaging, potentially providing insights into why some people are at risk of developing specific cancers. The findings also shed light on how these proteins' mutations contribute to various types of cancer, including mesothelioma and leukemia.
A University of Iowa-led research team identified a brain marker associated with aggression in toddlers, including smaller P3 brain waves accompanying tone changes. This finding could help diagnose aggressive behavior in young children before it becomes ingrained.
A UC Riverside-led study will focus on alcohol use disorders in Pacific Islander young adults, exploring factors that contribute to misuse and developing culturally tailored prevention strategies. The research hopes to gain a deeper understanding of the issue and inform effective interventions.
The James Webb Space Telescope has successfully connected its two halves, enabling them to communicate like they will in flight. This test was a significant step forward for the program and provided an opportunity for engineers to fix any issues before launch.
Alcohol consumption is common among patients with liver disease, associated with poor outcomes. The authors advocate for expanded treatment of alcohol use disorder in everyday clinical practice, including patients with advanced liver disease.
A study suggests that childhood habits, including diet and physical activity, can shape the gut microbiota of teenagers, which may contribute to developing conditions like diabetes and cardiovascular disease. Healthy lifestyle habits during childhood appear to promote a balanced gut microbiota in late adolescence.
Researchers found a new mechanism involving KCNB1 potassium channels that builds up toxins in brains affected by Alzheimer's disease. The build-up is caused by oxidation and can also contribute to other conditions such as traumatic brain injury.
A new study found that when women believed that selfies of thin and sexualized women had been edited, viewing these images had less negative impact on one aspect of their mental health. The study also found that participants judged women negatively for sharing edited pictures of themselves online.
Researchers from the University of Exeter discovered microplastics at depths of up to 60cm on beaches used by green turtles and loggerheads in Cyprus. The study found high levels of microplastics, which could alter conditions at hatching sites and impact turtle breeding.
Researchers found that daily lactoferrin supplementation can change salivary protein profiles in cancer patients, protecting their taste buds and odor perception. This could help patients recover from chemotherapy with improved nutrition and quality of life.
An observational study found significant differences in survival rates for patients treated by different EMS agencies, with odds of survival varying more than 50% between two agencies. The study included nearly 44,000 adults and treated by 112 EMS agencies in the US and Canada.
Three-dimensional simulations of the luminous blue variable star have revealed the physical forces behind its wild variations in brightness and spectrum. The simulations show that convection plays a key role in triggering outbursts, with helium opacity being a crucial factor.
A study using Drosophila has demonstrated that chromosomal instability promotes invasive behavior in epithelial cells, activating key signaling pathways. The researchers identified the oncogene Fos and tumour suppressor Capicua as crucial players in this process, paving the way for future treatments.
Research shows that modern couples are delaying marriage to focus on paying off student loans and saving. The study highlights how attitudes towards marriage, living together, and debt have changed over two generations, suggesting that debt is becoming a barrier to marriage.
Researchers from the University of Copenhagen have developed a new vaccine for hay fever that targets specific sugar molecules to improve vaccination efficacy. The vaccine has been tested on mice and in vitro tests, showing potential for increased effectiveness and reduced treatment time.
Scientists have discovered a compound that promotes social interaction among laboratory mice with autistic traits, offering new hope for treating autism. The finding builds on previous research showing oxytocin's potential benefits and develops a drug candidate to overcome its limitations.
Typhoon Trami was imaged by NASA-NOAA's Suomi NPP satellite on September 25, showing a wide eye and convection patterns. Cloud top temperatures near 190 Kelvin indicate potential heavy rainfall.
A new study by Cancer Research UK has found that immune cells in urine samples can accurately reflect the tumor environment, offering a non-invasive window into bladder cancer. This discovery could help monitor response to immunotherapy and identify patients most likely to benefit from treatment.
A new study reveals that common genetic variants can affect the risk of rare developmental disorders, changing our understanding of their causes. The research found that these variants can contribute to a range of conditions, including autism and schizophrenia.
Researchers discovered that E. coli bacteria discharge damaged proteins bundled inside minicells as a survival mechanism. Minicells can help bacteria resist antibiotics by kicking out damaged proteins.
Researchers at University of Hawaii at Manoa discovered that phosphates, a key element in life's building blocks, were generated in outer space and delivered to early Earth via meteorites or comets. This breakthrough suggests that the origins of life on Earth may have been influenced by extraterrestrial materials.
The IU School of Medicine and Regenstrief Institute will receive $3.4 million over five years from AHRQ and PCORI to train researchers in patient-centered outcomes research within learning health systems. The goal is to improve quality of care and patient outcomes by integrating research into daily care.