Researchers genetically engineered olfactory ensheathing cells to carry an anticancer drug, reducing tumor growth and improving survival in a mouse model. The treatment delivered the medication directly to glioblastoma cells while sparing healthy tissue, leading to a significant reduction in tumor size and prolonged survival.
Researchers discovered how the brain encodes speech production, finding that it controls both goals (speech sounds) and individual movements (lip, tongue, and larynx movements). This breakthrough aims to develop better brain machine interfaces to decode speech for paralyzed individuals.
A new study examines Canadian clinics marketing unproven stem cell treatments, highlighting regulatory gaps and potential risks to patients. The majority of marketed treatments target orthopedic and musculoskeletal conditions, with some companies advertising for a wide range of disorders.
Experts warn that Brexit will affect the UK's ability to tackle the illicit drugs trade due to exclusion from the European Monitoring Centre for Drugs and Drug Addiction (EMCDDA). The EMCDDA plays a crucial role in surveillance, data exchange, and policy-making, posing substantial risks to public health and safety.
A study published in the Journal of Endodontics found that smoking damages the pulp inside teeth, reducing their ability to fight illness and disease. This increases the risk of gum disease and delayed healing, with smokers nearly twice as likely to require a root canal as non-smokers.
A Rutgers-led study suggests that rapid Arctic warming is causing persistent dry and wet spells, leading to extreme weather events like droughts, heat waves, and storms. The frequency of these long-duration weather conditions has increased over recent decades.
Astrophysicists use 3D simulations to explain how luminous blue variables launch material into space through intense light and turbulent motion. The study sheds light on the violent mood swings of rare, massive stars that can shed billions of metric tons of material annually.
Researchers have created a low-cost smartphone system using nano-colorimetry and dark-field microscopy to detect lead in tap water. The system can identify concentrations as low as 5 parts per billion, posing a significant risk to health, especially for young children.
Astronomers detected a fast-moving jet from a neutron star with a strong magnetic field, challenging the long-held idea that magnetic fields prevent jets from forming. The discovery was made using the VLA, which revealed radio waves produced by the jet, characteristic of other jet-producing systems.
Dr. Robert Gillies, chair of Cancer Physiology and Radiology Research at Moffitt Cancer Center, receives the World Molecular Imaging Society's Gold Medal Award for his lifetime research in molecular imaging. His work focuses on understanding cancers as complex systems, leading to new cancer treatment options.
A new UMass Amherst study found that eating sunflower pollen dramatically reduced a protozoan pathogen infection in bumble bees. The researchers also discovered that incorporating sunflowers into pollinator gardens could provide a simple solution to improve the health of economically and ecologically important pollinators.
The GW Health Careers Opportunity Program aims to create a more diverse health care workforce by introducing high school students to a health sciences-focused curriculum. The program addresses regional disparities in healthcare access and outcomes through partnerships with public schools, community colleges, and healthcare employers.
Research from University at Buffalo suggests that unintentional social exclusion on Facebook and other social media sites can hinder thought processes, leading to negative emotions and increased susceptibility to advertising messages. The study's findings highlight the importance of critical thinking when interacting with these platforms.
Researchers found that infants with higher levels of Bifidobacterium had reduced antimicrobial resistance genes and lower frequency of resistant bacteria. This suggests that colonization by the microbe can help guard the infant intestine.
Researchers successfully located the epicenter of the September 2017 North Korean nuclear test using regional seismic data. The study's findings confirm that subsequent seismic events were not also nuclear explosions.
An observational study by researchers at Karolinska Institutet in Sweden found that bariatric surgery is associated with fewer complications during childbirth, including reduced risk of post-term delivery or uterine inertia. The study compared deliveries in women who had undergone weight loss after bariatric surgery to those who did not.
Researchers evaluated the safety of pimavanserin for treating Parkinson's disease psychosis, finding a lower mortality risk compared to quetiapine or combination therapy. The study provides reassurance for clinicians and families but highlights the need for further research on disease severity and cause of death.
New research reveals Arctic plant height increased by 20-60% over 30 years, with non-native species like vernal sweetgrass spreading into the region. Soil moisture plays a crucial role in changing plant traits, contrary to previous climate change models.
The University of Birmingham will conduct world-class research into a common heart condition in disadvantaged populations worldwide. The goal is to prevent and treat atrial fibrillation, which increases stroke risk five times.
Researchers found that a combination of multiple antibodies targeting distinct regions of HIV can suppress the virus and prevent resistance. In a pilot clinical trial, participants who received infusions of broadly neutralizing antibodies maintained viral suppression for over 15 weeks after stopping antiretroviral therapy.
Researchers studied manta ray filtration using physical modeling and CFD, discovering a novel non-clogging mechanism that resists clogging. The 'ricochet' separation process allows water to pass through while tiny particles are eaten, promising applications for industrial wastewater treatment and reducing microplastic pollution.
Researchers developed a theory of relaxation in hexagonal ice, which can indicate water purity and quality through dielectric polarization changes. The study used spectroscopy to analyze ice under different temperatures, revealing non-Arrhenius behavior.
Researchers have created a stable encapsulation system using cellulose and alginate to protect probiotics from stomach acid, allowing them to survive until reaching the intestine. This breakthrough may lead to more effective treatments for conditions like diarrhea and inflammatory bowel disease.
Researchers from the University of Toronto found that leaders tend to transfer their past cultural experience to new groups, creating ineffective cultures. This 'cultural transfer perspective' highlights the need for leaders to disconnect from their past experiences and analyze current circumstances to create effective cultures.
Psilocybin researchers propose moving the substance from a Schedule I classification to Schedule IV due to low potential for abuse and harm. This move would facilitate clinical trials and minimize logistical hurdles.
Researchers found specific physical changes to axons speed up neural transmission, leading to higher cognitive abilities. Axon myelination increased significantly during adolescence, corresponding with a dramatic increase in signal conduction velocity.
The presence of methane on Mars presents novel challenges to explain its formation and implications for potential life on the planet. Researchers recommend further studies to clarify geochemical processes and sources of methane.
Researchers create a new model for collective behavior within the brain, bridging the gap between EEG waves and random fluctuations. The technique has potential to reduce stress and onset of conditions like PTSD in military personnel.
Researchers at the University of Illinois have discovered how damaged liver cells repair themselves by reprogramming into an early stage of postnatal organ development. The findings reveal that injured liver cells undergo partial reprogramming, which is regulated by a specific RNA-binding protein called ESRP2.
The ESMERALDA MAES Explorer is an online tool that helps EU member states map and assess ecosystems and their services. The platform provides practical guidance to policymakers, scientists, and businesses on implementing ecosystem services mapping.
Researchers found a correlation between the type and severity of cold symptoms and the mix of bacteria living inside the nose. Six different patterns of nasal microbiomes were identified, each associated with differences in symptom severity and viral load. Probiotics did not have an impact on cold symptoms or nasal microbiomes.
The High Plains landscape was formed 20 million years ago through geological uplift and erosion, resulting in a unique ecosystem with hundreds of thousands of ephemeral lakes. These lakes provide crucial breeding and wintering habitats for millions of birds and recharge the Ogallala aquifer, North America's largest groundwater reservoir.
Scientists find DEET confuses critters by messing with neurons that help sense surroundings. Researchers also discover genetic and cellular mechanisms underlying response to the chemical.
Researchers have discovered a new approach to combat antibiotic-resistant bacteria by tricking them into taking up a molecule that causes harm. Gallium, a metal similar to iron, is used as a Trojan horse to disrupt bacterial nutrition and shut down essential processes.
After severe weather events, households may use generators, leading to carbon monoxide (CO) poisonings. CO is a silent killer with no odor or taste, caused by malfunctioning appliances, and can cause coma, heart attack, and death. Regular appliance checks and generator usage precautions can prevent CO poisoning.
Researchers at IBS have developed a new method to generate extreme-ultraviolet emissions, opening doors for high-resolution imaging, ultrafast spectroscopy, and next-generation lithography. By controlling electron motion using laser pulses, they created coherent radiation with specific wavelengths.
Researchers at Purdue University have found that red and blue LED lights can lead some birds to fly away, potentially preventing bird strikes. The study used a single-choice test to measure avoidance behavior in brown-headed cowbirds.
QUT researchers have discovered a drug that prevents laminitis in ponies with equine metabolic syndrome. The drug, velagliflozin, works by causing the kidneys to excrete more glucose in the urine, taking pressure off the pancreas and lowering insulin levels.
A study by North Carolina State University found that sunflower pollen reduces infection rates in bees and improves colony health. However, it also had a deleterious effect on honey bees, leading to higher mortality rates compared to other diets.
A new study published in Earth and Planetary Science Letters proposes that plate tectonics could have started as early as the planet's formation. Researchers analyzed noble gas isotopes Helium-3 and Neon-22 to establish a timeline of Earth's tectonic plate cycling, providing insight into the planet's earliest conditions.
Scientists discovered that methane absorption is 10 times stronger over desert regions like the Sahara Desert and Arabian Peninsula than elsewhere on Earth. Cloud cover also enhances methane radiative forcing, with increased forcing found over oceanic stratus cloud decks and the Intertropical Convergence Zone near the equator.
Researchers identified a collapsed underground cavity and multiple small earthquakes after the September 2017 North Korean nuclear test, providing insights into the detection of nuclear explosions. The study's findings also shed light on seismic stress in the region and potential aftershocks.
A research study found that machine learning outperformed human experts in predicting social outcomes for people at high risk of psychosis (83% accuracy) and those with recent-onset depression (70%). This could lead to personalized treatments to improve social functioning.
A new analysis warns that delaying efforts to cut greenhouse gas emissions could result in substantial economic costs, potentially exceeding the benefits of limiting global warming to 1.5 degrees. The study suggests that the remaining carbon budget for this goal is very small, requiring unprecedented scale and significant investment.
Developed by City University of Hong Kong, the mini delivery-robot can carry heavy loads and adapt to adverse environments. Its unique design with hundreds of pointed legs reduces friction significantly, enabling efficient movement inside the human body.
A new study from CHEO Research Institute found that children aged nine and 10 who meet Canadian 24-hour Movement Guidelines for physical activity, screen time, and sleep time have superior global cognition. The results suggest a positive relationship among childhood global cognition, future academic success, and lower all-cause mortality.
Researchers have developed a gel-based chemotherapy that can shrink melanoma skin tumors in mice by penetrating deep into the skin. The gel, called transfersome, was found to slow tumor growth when applied daily and administered intravenously every other day, with results showing a significant reduction in tumor size.
Researchers observed a strongly magnetized accreting X-ray pulsar using the Karl G. Jansky Very Large Array and NASA's Swift space telescope. The discovery reveals a new class of jet-producing sources, contradicting previous expectations about strong magnetic fields.
A study of 20,244 people from 16 European countries found that those who experienced socioeconomic hardship in childhood scored lower on tests of verbal and memory skills. Researchers suggest that addressing childhood poverty could help protect cognitive health.
Researchers are investigating how a gene that regulates estrogen and neurotransmitter levels could be tied to cognitive decline in patients undergoing chemotherapy. The study aims to understand the underlying factors of treatment-related cognitive dysfunction, also known as chemo brain.
The NIAID Strategic Plan for Tuberculosis Research prioritizes expanding fundamental knowledge of TB by using modern tools to better understand the disease. The plan also focuses on developing rapidly accurate inexpensive point-of-care tests for different forms of TB, as well as identifying host and microbial biomarkers.
Researchers discovered that tweaking pH balance and oxygen in a CF lung model can help eradicate pathogenic bacteria while minimizing antibiotic resistance. The study found two distinct communities of microbes in CF lungs: anaerobes thriving in low-oxygen and low-pH regions.
Researchers found that multidrug-resistant bacteria in CF patients' airways are associated with lower microbial diversity and more aggressive disease. The study suggests that judicious use of antibiotics is crucial to help patients live longer, but new methods can help target infectious bacteria selectively.
Researchers have developed a novel immunotherapy that can suppress HIV for months at a time, using a combination of two anti-HIV antibodies. The treatment, called broadly neutralizing antibodies (bNAbs), has shown promising results in clinical trials, with some patients experiencing sustained viral suppression for over four months.
A Japanese collaboration has successfully tracked hydrogen movement in solids using negative muons, a technique that could aid the development of hydrogen storage materials. By detecting local nuclear magnetic fields, researchers were able to study the dynamics of light elements in a solid from the fixed point of the nucleus.
A University of Utah engineering study shows that smart controllers for home heating and cooling systems can clean pollution with minimal additional energy costs. The 'SmartAir' setting, which turns on the HVAC fan based on both temperature and air quality, cleaned the air almost as well as continuous operation but used 58% less energy.
Researchers found that hummingbirds and nectar bats hover in different ways, with the former generating more lift relative to drag. Nectar bats' hovering form is a blend of fruit bats' and hummingbirds' hovering, with twisted wings on the upstroke.
The Bureau of Reclamation is supporting a six-year study to assess the impact of its projects on endangered pallid sturgeon in the upper Missouri River. The study aims to preserve the species and potentially lead to its downlisting, with data gathering focused on reproduction conditions and habitat analysis.
Researchers at Linköping University found that uterus transplantation with living donors is ethically comparable to altruistic surrogacy, citing potential pressures on donors and lack of research on child outcomes. The study suggests that decision-makers should consider the parallels between the two practices.
A study by University of Pennsylvania researchers identified a rare example where being older improves tissue function, leading to reduced scar formation. The key factor is a compound called stromal cell-derived-factor-1 (SDF1), which is secreted in the bloodstream and is more abundant in younger individuals.