Researchers developed an integrated fabrication process to design soft robots on the millimeter scale with micrometer-scale features, enabling changes in structure, motion, and color. The new technology paves the way for a new generation of flexible microrobots for medical and environmental tasks.
Five low- and middle-income countries lack trained health workers and essential medicines, hindering readiness for noncommunicable diseases. Policymakers can engage private sector in addressing NCD burden through partnerships, medicine procurement, and service financing.
A new method has been developed to deliver curcumin to cancer cells, enhancing its effectiveness in treating various cancer types. The approach involves creating a sophisticated metallocyclic complex using platinum that increases curcumin's solubility and synergy.
New research from Singapore Management University suggests that venture capitalists' reputations can be damaged when their endorsed companies fail to meet expectations. The study found that VCs create high expectations for their portfolio companies, which can have long-lasting consequences for their own reputations.
Researchers develop solar-blind UV photodetector with high responsivity and low dark current, enabling detection of deep ultraviolet emission. The joint work showcases the possibility of manufacturing new-generation photodetectors using existing silicon technologies.
A study reveals evidence of community collapse in Mojave birds, with 43% loss of previously documented bird species over the past century. Climate change, particularly decreased precipitation, is associated with the decline in Mojave birds, while surface water presence is linked to increased species richness.
A new study by the University of York found that dilute concentrations of Prozac make female starlings less attractive to males during courtship. The researchers discovered increased male aggression towards females receiving the medication, leading to a higher risk of mate failure and population decline.
A study found similar trends in streamflow in natural and human-modified watersheds, indicating climate-induced changes. Streamflow decreased in the southern US and increased in northeastern states and Canadian prairies.
A University of Washington study found that children use repetition, increased volume, and variation to communicate with nonresponsive voice technology. Parents often recognize their child's intended message and fill in the gaps, but a device could also be designed to engage in partial understanding.
Researchers investigate intrinsic biogeophysical feedbacks that may lead to 'Hothouse Earth' conditions despite reduced human emissions. The study highlights the risk of exceeding global average temperatures in interglacial periods of the past 1.2 million years.
Research finds that pride serves an evolved function in human nature, helping individuals weigh self-interest against social approval. The study reveals a close link between pride and the values of those around us, suggesting it's a win-win rather than a sin.
Researchers developed a smart wristband that can monitor personal health by counting blood cells, bacteria, and air particles. The device sends data wirelessly to an Android smartphone for processing and analysis, enabling rapid diagnosis of illnesses and tracking of environmental exposures.
Researchers develop targeted approach to treat glioma, using microparticles to deliver drug directly to brain. The treatment targets a specific mutation found in 20-25% of gliomas and has shown promise in extending patient survival.
A Johns Hopkins Medicine study identified CMPK2 and BCLG as potential new drug targets for the treatment of HIV. The researchers found that these genes are selectively activated in response to type 1 interferon, a drug once used to treat hepatitis C.
Researchers found that injectable trace mineral Multimin90 improved conception rates in some herds, but not others. In one study, selenium and copper status improved compared to saline injections. The value of injectables lies in ensuring every animal receives the supplement at a chosen timing.
Researchers at Vanderbilt University have identified a key enzyme that drives neuron death in neurodegenerative diseases, including Alzheimer's and ALS. The enzyme histone deacetylase 1 (HDAC1) modifies a molecular motor that triggers signaling agents to travel down the axon, killing the neuron.
Research reveals that genetic factors and age are the strongest predictors of humoral immune responses to common pathogens and vaccines. The study also found that older individuals and women exhibit stronger antibody responses against most antigens.
Scientists at University of California San Diego School of Medicine have successfully created a line of spinal cord neural stem cells that can be used to model diseases and potentially provide a scalable source of replacement cells for spinal cord injuries. The diverse cells, derived from human pluripotent stem cells, show promise in a...
Pediatricians in a telemedicine service face difficulties diagnosing from a distance, managing patients' expectations, and working alone. To overcome these challenges, they use intuition, experience, and protocols, highlighting the need for special skills and training.
A new study suggests that organic materials found in ancient meteorites formed through basic chemical reactions during the Solar System's infancy. The research provides insights into the potential habitability of other planetary systems.
A new study found that female patients treated by male physicians had lower survival rates compared to those treated by female physicians. Increasing the presence of female physicians in emergency departments may improve outcomes for these patients.
Meteorite chondrules reveal that oxygen and volatile elements increased in the inner Solar System until around 4.567 billion years ago. Volatile element delivery continued to increase after this point, supporting a model of Mars' early formation under oxidizing conditions and Earth's accretion under reducing conditions.
A new high-sensitivity blood test for cardiac troponin has been found safe and effective in diagnosing heart attacks faster than traditional methods. The test ruled out heart attack in 30-83.8% of patients within three hours, compared to 80.4% with conventional testing.
A new study suggests that excessive screen time is contributing to an increase in nearsightedness among children, with symptoms including dry eye and blurred vision. Parents can take steps to mitigate this by encouraging outdoor activities, using good posture, and taking regular breaks from screens.
Researchers at Scripps Research and Bristol-Myers Squibb developed a new tool, called phosphorus-sulfur incorporation (PSI), to precisely control the 3D architecture of thiophosphate linkages in nucleic acid therapeutics. This technology enables the creation of single isomers with hundreds of thousands of stereoisomers.
A 19-year review of nearly 582,000 heart attack cases reveals that female patients have a significantly higher survival rate when treated by women doctors. The study's findings also suggest that male doctors with more female colleagues in the ER can improve survival rates for female patients.
Researchers have uncovered the remnants of the early solar system with the discovery of an ancient igneous meteorite containing silica-rich crustal rocks. The oldest recorded igneous meteorite, dating back 4.565 billion years, provides valuable insights into planet formation and volcanic rock compositions in the early solar system.
A study of over 500,000 observations found that female heart attack patients treated by male physicians had lower survival rates. Survival rates improved when there were more female physicians in the emergency department or when male physicians were exposed to more female patients.
Researchers found a broad range of cost per dose delivered across Indian states, with personnel costs accounting for 57% of total costs. The weighted average national cost per dose was $2.29, which is lower than the current allocation of $25 per child.
Researchers report significant declines in forest soils' methane uptake, attributed to increased precipitation and hydrological flux. A literature analysis reveals a 77% global average decrease in methane uptake from 1988 to 2015.
Researchers found that states expanding Medicaid eligibility in 2014-2015 saw a significant increase in diabetes medication prescriptions, with a 30% rise per 1,000 people. This growth was particularly notable for newer, more advanced forms of insulin and other medications, suggesting improved treatment outcomes.
Researchers at Lund University tracked the flight height of two small bird species migrating from Scandinavia to Africa, finding they flew as high as 3,950m. The study used a data logger to measure acceleration, air pressure, and temperature during flight, revealing the birds' altitude adjustments in response to changing wind conditions.
Researchers found unique chromosome rearrangements in mosquito larvae from the Caucasus region, indicating a complex genetic structure. The study suggests that the region's fauna has unified geographically but divided evolutionarily, with significant genetic distance between populations.
Researchers developed a drug-delivery system that dissolves clots in minutes, limits scarring, and preserves cardiac function. The targeted treatment may improve patient outcomes by allowing for earlier treatment of heart attacks without surgical intervention.
A UCL-led study found that stress enhances people's ability to process and internalize bad news, reversing the typical optimism bias. Under stressful conditions, individuals become more vigilant to bad news, even when unrelated to their anxiety source.
Research finds that restricting student and high-skilled visas has little impact on overall migration, while limiting family and low-skilled visas reduces migration but diverts aspiring migrants to unauthorized channels. Enforcement of unauthorized migration is also inefficient.
Scientists discovered that gas bubbles rising to the surface can alter volcanic gas composition, which affects eruption forecasts. The findings also suggest a new pathway for chemical changes in gases during large-scale eruptions.
Hurricane Hector was observed in detail by NASA-NOAA's Suomi NPP satellite, providing forecasters with valuable information on its clouds and structure. The storm maintained its strength with sustained winds of 120 mph and an estimated central pressure of 962 millibars.
A study found that more than 70% of tweets about e-cigarettes were posted by robots, while human users showed strong support for vaping. The team analyzed nearly 194,000 geocoded tweets and identified adolescent Twitter users as particularly enthusiastic about e-cigarettes.
The guidelines outline lessons learned by experts in various fields to identify early signs and symptoms of treatment-related toxicity, detailing ways to manage it. Key recommendations include monitoring for cytokine release syndrome and addressing parent and/or caregiver concerns.
Researchers found a significant connection between probiotic use, bacterial overgrowth in the small intestine, high levels of D-lactic acid, and brain fogginess. The study suggests that excessive probiotic use can lead to severe bloating and disorienting brain fog.
The researchers discovered a connection between the colouration of clownfish and the toxicity of sea anemone species they live with. The more venomous anemones have less white stripes on their hosts, suggesting the bright colouration has a protective function.
A new study warns that reducing greenhouse gas emissions may not be enough to avoid a 'Hothouse Earth' state, where temperatures could rise by 4-5°C and sea levels increase by 10-60m. The authors call for accelerated transition towards an emission-free world economy.
Research by Peter Selb and Simon Munzert found Hitler's 455 public appearances had surprisingly small effect on electoral outcomes. His personal involvement only positively impacted the 1932 presidential election, but overall campaign effects were minor.
Researchers used heart imaging technology to study hearts of pregnant women with severe preeclampsia, finding higher contraction pressures in right ventricles and abnormal relaxation rates. This led to overwork and poor pumping ability, increasing risk of heart failure, stroke, and heart attack.
A computational model simulated potential migrants' decisions and found that restrictive policies, such as limiting visas, reduce immigration by up to 32%. However, these restrictions also increase unauthorized immigration, which may be difficult to offset with increased enforcement.
A team of Chinese astronomers has discovered the most lithium-rich giant known to date using the LAMOST telescope. The star's lithium abundance is approximately 3,000 times higher than that of typical giants, providing valuable insights into the universe's evolution and Big Bang theory.
A graduate student at Virginia Tech Carilion Research Institute is investigating how adenovirus affects gap junctions in the heart, which can lead to arrhythmia. The research aims to understand the pathways used by the virus in sudden cardiac death and potentially develop therapies for other forms of cardiac disease.
Researchers found significant correlations between tornado activity and Arctic sea ice extent, particularly in July. The study suggests that Arctic sea ice loss controls the jet stream's path, leading to reduced tornado formation.
Endometrial cancer is found in most cases of postmenopausal bleeding but the risk is relatively low at 9%. Early detection strategies for postmenopausal bleeding are needed to improve survival rates.
Scientists found that an ancient and unrelated endogenous retroviral element is inserting itself into the new retrovirus via recombination, deactivating it. This process may be a molecular defense mechanism of hosts against new retroviral attacks.
A low-protein diet during pregnancy and lactation may increase the risk of prostate cancer in offspring, according to a study with rats. The study found that females fed a low-protein diet had offspring with preneoplastic alterations capable of interfering with glandular function.
Researchers at Stanford University have developed a system that automatically renders accurate sounds for complex animated content, such as splashing water or colliding objects. The system takes into account the vibrations of each object and how they excite sound waves, resulting in highly detailed and realistic sounds.
A laboratory and natural experiment demonstrate how threat dissolves human optimism bias, allowing individuals to flexibly shift between optimistic and pessimistic patterns. The study suggests that stress can improve the processing of bad news, enabling people to adapt their optimistic outlook to changing environmental conditions.
Next-generation metabolomics may facilitate the discovery of new antidepressants by providing broader coverage and higher resolution than traditional methods. The technique has demonstrated great potential in accelerating pharmaceutical R&D, particularly for natural products like albiflorin, a promising multi-target drug candidate.
A clinical trial using stem cell transplants aims to grow a new immune system for people with untreated Crohn's disease. This innovative approach may help reduce gut inflammation and improve quality of life for patients suffering from the condition.
The largest randomized trial on genetic screening before embryo transfer found no difference in live birth rates between groups with and without the procedure. However, there was a lower miscarriage rate and fewer embryo transfers in the group that received genetic screening.
Researchers found that bright light therapy increased systolic and diastolic blood pressure by 10 mm Hg in rats with inherited hypertension, a effect that persisted for several hours. In contrast, healthy animals with normal blood pressure showed no changes.
Researchers at the Marine Biological Laboratory have identified a key molecule driving chemoattraction between sperm and egg cells in marine invertebrates. This molecule allows sodium ions to flow into the sperm cell, transporting protons out of the cell and increasing the pH, enabling the Ca2+ pulses needed for fertilization.
A new study by Brigham and Women's Hospital researchers models allergic lung inflammation in mice, revealing the role of neutrophil extracellular traps (NETs) in triggering and amplifying an allergen-initiated immune response. The findings have implications for designing more precise clinical trials for severe asthma treatment.