Researchers studied blood samples from 3,740 children and 1,074 adults in Managua, Nicaragua, after the 2016 Zika epidemic. The study found a high post-epidemic seroprevalence of 36% in children and 56% in adults, with immunity rates higher in females and increasing nonlinearly with age.
A new study reveals that even deep coral reefs in Palau are exposed to thermal stress at intervals different than those near the surface. By combining sea level and temperature data sets, researchers developed a forecast tool for predicting temperature stress on corals up to 150 meters below the surface.
A study of over 40,000 patients found that myocardial injury, major bleeding, and sepsis contributed to nearly three-quarters of all deaths after noncardiac surgery. Most deaths were linked to cardiovascular causes, with cardiologists playing a crucial role in preventing further complications.
A study of over 1,000 motor vehicle accident survivors found a common genetic variant in the stress response gene FKBP5 linked to increased chronic pain. The researchers discovered that addressing this interaction between the genetic variant and post-traumatic stress may represent a supplemental or alternative treatment option.
Researchers have successfully created 3D human liver tissue from human stem cells and implanted it into mice with liver disease, demonstrating improved liver function. The study showcases a promising approach to developing human liver tissue implants that could reduce the need for animal testing.
A new study suggests that paternal diet influences offspring health by affecting sperm DNA methylation tags and seminal plasma immunological responses. Mice fed a low-protein diet had overweight offspring with dysfunctional metabolism, highlighting the importance of a healthy father's nutrition for child well-being.
A new analysis of the LEADER trial suggests liraglutide treatment reduces the risk of death from heart attack and nonfatal stroke in people with Type 2 diabetes, regardless of their cholesterol levels. The study found that liraglutide also lowers LDL-C levels, an important marker of developing heart disease.
Qrypt has licensed a novel cybersecurity technology from Oak Ridge National Laboratory to fortify encryption methods. The company will incorporate the quantum random number generator into its platform, using unique and unpredictable encryption keys to create virtually impenetrable communications.
By 24 months old, children demonstrate awareness that their behavior can be positively or negatively evaluated by others. The study found that even young toddlers are attuned to the judgments of others and adjust their behavior accordingly.
Scientists discover TREM-1 amplifies inflammation, leading to liver scarring and cirrhosis. Targeting this receptor may prevent fibrosis and cancer development.
Researchers found that only 8% of studies included some primary care patients, and none were conducted solely in primary care settings. Primary care physicians should be represented in advisory boards, considered for study grants, and primary care patients need to be included in trials of drugs used in primary care.
Endurance athletes show more left atrial fibrosis than non-athletes, with the condition linked to a higher risk of arrhythmias and atrial fibrillation. The study suggests that increased left atrial fibrosis may help explain the higher incidence of arrhythmias in endurance athletes.
Researchers found that fishing in the Phoenix Islands Protected Area doubled before its implementation, leading to excess fishing equivalent to what was prevented by the reserve for 1.5 years. This suggests that anticipating marine reserves can trigger overfishing, undermining conservation efforts.
The Vibrio cholerae bacterium has evolved skills to survive in aquatic environments by 'hitchhiking' on predatory amoebas and establishing a replication niche within their osmoregulatory organelle. This adaptation may have contributed to the emergence of V. cholerae as a major human pathogen.
A study published in the European Heart Journal reveals that microvascular dysfunction is a prevalent underlying disease mechanism in patients with heart failure and preserved ejection fraction. The research highlights the importance of identifying patients at risk and developing targeted therapies to improve outcomes.
A new study led by Harvard T.H. Chan School of Public Health warns that high CO2 levels could lead to widespread nutritional deficiencies, affecting 1.9% of the global population by 2050. The research estimates that 175 million people will become zinc deficient and 122 million will become protein deficient due to lower crop yields.
A study found that air pollution exposure was associated with decreased cognitive test scores, particularly in verbal abilities. Reducing fine particulate matter concentrations could lead to significant improvements in cognitive performance, equivalent to a shift from median to 63rd percentile scores.
The study provides guidance on synthesizing high-quality graphene with less domain boundaries. Researchers found that the lattice orientation of graphene is determined by the Cu crystal it is nucleated on, regardless of the substrate's crystallinity.
Researchers from Massachusetts General Hospital found that immune cells responding to a stroke or brain injury in an animal model are more likely to come from the skull's bone marrow. Microscopic channels were discovered in the skull's inner layer, allowing inflammatory cells to migrate directly to the brain surface.
Researchers at Yerkes National Primate Research Center have successfully reversed the effects of parental stress on offspring by exposing parents to behavioral interventions. The study found that this approach breaks the cycle of intergenerational stress, reducing sensitivity and structural imprints in offspring.
Researchers at Stanford University School of Medicine discovered that people with cardiomyopathy have abnormally short telomeres in their heart muscle cells. This finding opens the door to new research and drug discovery, potentially allowing for the identification of individuals at risk for heart failure due to genetic defects.
A large study found that care coordination strategies significantly reduce symptoms of depression and improve health in seniors with multiple chronic diseases. The review included 25 studies and 12,579 older adults, highlighting the potential benefits of managing co-existing chronic illnesses in a coordinated manner.
A recent survey found that about 4.5% of US adults use e-cigarettes, with higher rates among young adults and those in the LGBTQ community. E-cigarette use also varies by state, with estimates ranging from 3.1% in South Dakota to 7% in Oklahoma.
Researchers aim to address muscle power deficits in children with cerebral palsy, using a combined impairment and task-specific approach. The study will investigate the effects of PT3 on functional walking capacity, muscle performance, and architecture.
A study by University of California - San Diego found that 63% of breast milk samples from mothers using marijuana contained THC, the primary psychoactive component. The study suggests that while the amount of THC in breast milk is relatively low, more research is needed to understand its potential effects on nursing babies.
The COMMANDER HF trial found that rivaroxaban did not significantly reduce the risk of death, myocardial infarction, or stroke in patients with recent worsening of chronic heart failure and coronary artery disease. Rivaroxaban was associated with a lower rate of nonfatal stroke, but a higher risk of major bleeding compared to placebo.
Researchers used fMRI data to analyze brain activity of infrequent and frequent news readers, finding that the former group was better at predicting article popularity. The study suggests that people who don't normally read the news are more representative of general population trends.
A new UNLV study reveals that real estate prices for homes in wildfire-prone areas fall initially after a blaze, but rebound within one to two years. The phenomenon may pose a curse, as homebuyers prioritize environmental amenities over fire risk.
Health policy experts argue that expunging the program could worsen educational debt in America and threaten the medical workforce. The authors call for clarity and swift decisions to resolve the uncertainty, which is particularly unfair to recent graduates who are already facing significant loan debt.
Tafamidis improves survival and quality of life, reducing hospitalizations in patients with transthyretin amyloid cardiomyopathy. The therapy delays neurologic progression in a similar condition, and has been approved for this condition in the EU.
A new study led by Ohio State University found that algae poses a greater threat to freshwater fish vision than sediment, causing a 40% decrease in their ability to see in cloudy water. This could jeopardize the future of walleye and other fish populations if harmful algal blooms persist.
Researchers identified epigenetic changes that accompany glioblastoma progression and predict patient survival. DNA methylation sequencing can be used to predict clinically relevant tumor properties.
Tropical cyclone Lane was affected by strong westerly winds, causing a significant shift in its strongest storms east of the center. Despite this, the storm strengthened back into a tropical storm on August 27.
The article highlights the importance of providing care for transgender patients by incorporating patient-centered approaches and creating more inclusive healthcare environments. Key strategies include using preferred names, pronouns, and gender-affirming language, as well as training staff on trans-specific health issues.
A new study finds that toddlers are attuned to how others may be judging them and modify their behavior accordingly. Children between 14 and 24 months show inhibition when being watched with a neutral or negative expression, but press the buttons associated with positive responses more often.
Researchers found that ant colonies with as few as six individuals experienced significant benefits from group living, including better-surviving babies and faster growth. The study suggests that increases in group size alone can create benefits for small colonies, challenging the idea that strong groups require strong leaders.
Scientists from Tokyo Metropolitan University studied how microswimmers navigate gels with contrasting results based on swimmer features and size relative to the gel's mesh. They discovered two mechanisms for achieving motion, one through breaking time-reversal symmetry and the other by modulating arm amplitudes
Subordinate females in naked mole-rat colonies become more responsive to pup vocalizations after consuming queen's feces or estradiol, suggesting a unique mode of communication.
Researchers at Cedars-Sinai Medical Center have developed a simpler and more accurate method to estimate body fat percentage than the widely used BMI. The new relative fat mass index (RFM) formula uses only height and waist circumference measurements, providing a better measure of body fatness without requiring expensive equipment.
Researchers found that the Ross procedure reduced death from all causes by 46% compared to mechanical valve replacement, while also decreasing stroke and bleeding complications. However, patients undergoing the Ross procedure were more likely to require reoperation due to graft failure.
A phase three clinical trial has shown that tafamidis can reduce deaths by 30% and cardiovascular-related hospitalizations by 32%. The treatment also slows the decline in quality of life among patients with transthyretin amyloid cardiomyopathy. If approved, it would be the first medical therapy for this life-threatening disease.
Researchers designed video games to enhance heuristic judgment in emergency medicine physicians. The intervention improved accuracy in trauma triage decisions, with participants who used the games showing a 17-18 point lower under-triage rate compared to those receiving no intervention.
NASA's Terra satellite detected three areas of strong water vapor concentrations in Tropical Depression 25W, indicating potential for heavy rainfall and intensification.
Researchers discovered that beluga whales and narwhals undergo menopause, mirroring killer whales' behavior. This reproductive strategy may have evolved due to increased relatedness among family members and the need for older females to contribute to group survival through knowledge sharing.
MIT researchers create a new technique to alter membrane proteins, making them more accessible for structural studies. The QTY code allows for the substitution of hydrophobic amino acids with hydrophilic ones, enabling water-soluble proteins that can be analyzed using X-ray crystallography or NMR.
A study by McLean Hospital calls for a unified approach to preventing suicides and other self-injury deaths. Researchers found that the estimated mortality rate from self-injury surpassed diabetes, prompting experts to emphasize the need for more effective prevention strategies.
Female refugees are more likely to become naturalized US citizens than male counterparts, according to a recent study. The study found that higher levels of education and longer US residency also contribute to increased naturalization rates among refugees.
A study defines mechanisms behind focused-ultrasound-assisted treatment of brain tumors, improving drug delivery across the blood-brain barrier and into abnormal tumor tissues. The approach enhances permeability of endothelial cells lining tumor blood vessels, increasing cellular uptake of anti-cancer drugs.
Researchers discovered a protein called HIF helps heart cells survive after a heart attack, but its effect is blocked by fats accumulating within the heart muscle in people with diabetes. Repurposed drugs that activate HIF may help prevent lasting heart muscle damage and improve recovery in Type 2 diabetics.
Japanese researchers from Osaka University analyzed Hayabusa particles to determine the age of asteroid Itokawa, finding it formed 4.6 billion years ago and was destroyed 1.5 billion years later. The study used precise isotope analyses to clarify the chronology of the asteroid's evolution.
A study published in PLOS ONE found that restricting high-sucrose diet to active times reduced fat levels in rats. The research team limited the diet to nighttime, resulting in lower blood and liver fat compared to an unrestricted diet.
Studies with rodent models show reduced anxiety and improved brain function with early treatment using the histone deacetylase inhibitor LBH589. This approach may offer a new therapeutic strategy for Huntington disease.
A study by Boston University School of Medicine researchers suggests that HIV RNA expression inhibitors can diminish atypical inflammation and restore immune function in HIV-infected individuals on combination antiretroviral therapy (cART). Chronic viral infection leads to immune activation, causing non-AIDS complications such as cardi...
Researchers discovered tiny tunnels in the skull that connect bone marrow to the lining of the brain, enabling immune cells to quickly reach injured tissue. The study found that these channels play a crucial role in inflammation and may be important in various brain disorders.
Hydroxyl-terminated diamond surfaces created via water vapor annealing maintain atomically flat surfaces and remove two-dimensional hole gas layers, enabling high-temperature operation.
The University of Texas at San Antonio has developed the world's smallest medical robot, made up of nanocomposite particles that can be remotely controlled by an electromagnetic field. These robots have the potential to target cancerous cells for treatment and potentially treat Alzheimer's disease.
The discovery of the Bombali virus in Sierra Leone's bats marks a significant breakthrough for the PREDICT project, which aims to find viruses before they spillover into humans. The finding suggests that bats are likely hosts of ebolaviruses and underscores the importance of understanding their role in preventing Ebola outbreaks.
Researchers develop radiomic signature to predict efficacy of immunotherapy in patients with solid tumors. The algorithm analyzes CT scan images to extract biological information, providing a predictive score for treatment effectiveness.
Researchers developed a new method to measure degeneration of sensory neurons grown in a lab, improving the screening of experimental therapies for neurodegenerative diseases. The automated test uses software-assisted analysis to accurately assess nerve cell densities and shapes.
Researchers have proposed a new model for Jupiter's birth, revealing three distinct phases of growth. The first phase was characterized by rapid accretion of small pebbles and core building, followed by slower accretion of larger planetesimals that brought energy to the growing planet.