Researchers at Karolinska Institute found that including dying cells in protein analysis improves target identification for cancer drugs. They also identified proteins upregulated in all detached and dying cells, which may be promising chemotherapeutic targets.
A recent study found no correlation between circulating bone turnover markers and hip fracture risk among postmenopausal women. The research adds to the existing evidence that these markers are not useful for predicting hip fracture risk.
Researchers found that barnacle density decreases with depth and extent of coral cover, suggesting a preference for spreading out. This study provides insight into the importance of barnacles in reef erosion and their potential as indicators of reef health.
A team of researchers from the University of Warsaw has successfully created and detected correlations in a many-body system of ultra-cold atoms, showcasing the phenomenon of quantum non-locality. This achievement builds upon previous work by John Bell, who proved that quantum mechanics predicts correlations that contradict local realism.
Men who experienced a male friend or family member's suicide found solace in self-care and social connections, revealing that masculinity is not mutually exclusive with emotional expression. The study highlights the importance of acknowledging men's grief in a way that respects their values.
Research suggests that forgetting can increase long-term retention and information retrieval, ultimately enhancing learning. By changing context, forgetting can also enrich how information is encoded and retrieved.
A new study reveals that half of Parkinson's patients taking dopamine agonist drugs may develop impulse control disorders such as compulsive gambling, shopping, or eating. The five-year cumulative incidence of these disorders is higher in those who have ever taken the medications compared to those who never took them.
A team of researchers has identified 27 new viruses in bees from around the world, shedding light on the impact of viral pathogens on bee health and agriculture. The discovery was made using a novel high-throughput sequencing technique that efficiently detected both known and unknown viruses.
A new study in Respirology reveals that Southeast Asia's annual haze is associated with increased hospital admissions for respiratory problems. Respiratory admissions at Universiti Kebangsaan Malaysia Medical Centre were significantly higher during haze periods, with 27.6 cases per week versus 15.7 cases per week.
A new study aims to clarify the role of the APOL1 gene in predicting kidney-transplant failure. By genotyping deceased and living African-American donors and recipients, researchers hope to determine if high-risk variants can replace race as a risk factor for discarded kidneys.
Researchers from Turku Centre for Biotechnology and Aalto University used label-free quantitative proteomics to identify over 4000 proteins expressed in Th17 and iTreg cells. The study, published in PLoS Biology, reveals protein expression changes that may be targeted in immunotherapy for diseases like cancer and autoimmunity.
Dogs use different parts of their brains to process negative and positive emotions cued by human facial expressions. They show increased heart rate and stress when exposed to angry or fearful faces, but not surprised ones.
Researchers used single-cell transcriptomics to characterize stromal cells in fat tissue and discovered a subpopulation called Aregs that suppresses adipogenesis. These findings provide potential new avenues for treating metabolic diseases like type-2 diabetes.
Researchers at Cornell University developed a new method to monitor urinary tract infections using cell-free DNA profiling, providing valuable information about the infection's dynamics and patient response. This technique has the potential to diagnose rare infections earlier and improve outcomes in kidney transplantation.
A new study reveals that having a meal increases oxygen consumption in human brown adipose tissue (BAT) as much as cold exposure does. This finding suggests that eating may be an effective way to activate BAT and support metabolic health.
A pilot study found crystalline particles of titanium dioxide in pancreas specimens with Type 2 diabetes, suggesting a possible link between the white pigment and the disease. The study suggests that increased use of titanium dioxide may contribute to the global rise in T2D cases.
Researchers from Yunnan University investigate recent research progress on QDs/GR composites, highlighting their industrial preparation methods and commercial applications. The synergistic effects of the QDs/GR composite materials enhance their optical gain, charge separation, and carrier mobility.
Researchers have discovered a potential diagnostic method for pancreatic cancer in patients with early onset diabetes by analyzing blood sugar levels over time. The ENDPAC score model identifies patients at high risk of developing pancreatic cancer, providing a new way to diagnose the disease at an earlier stage.
The China ban on non-industrial plastic waste has displaced around 111 million metric tons of plastic waste, which was previously exported to the country. This shift will require high-income countries to develop more robust recycling programs domestically and rethink the use and design of plastic products.
A new study explores the phenomenon of radicalized European youth, finding that adolescent psychopathology plays a role in the radicalization process. The study proposes a comprehensive three-level model to explain the phenomenon, which considers individual, micro-environmental, and macro-environmental factors.
A recent study found that asking individuals to set up a long-term screening schedule can increase adherence to evidence-based guidelines for cancer screening. In the study, 62.6% of participants made decisions reflecting USPSTF's recommendations when asked to choose a screening schedule for the next 10 years.
A Northwestern University team developed a novel nanolaser that changes colors by controlling the spacing among metal nanoparticles, inspired by chameleons' skin structure. The laser is robust, tunable, reversible and highly sensitive to strain.
Researchers found that women with autologous breast reconstruction had better satisfaction, quality of life, and sexual well-being two years post-surgery. However, nearly one-third of patients experienced complications, with failure rates significantly lower for autologous reconstruction.
The University of Louisville launches the Envirome Institute with a $5 million gift, supporting research on the holistic approach to studying how the human-environment interrelationship impacts people's lives. The institute aims to introduce a new approach to health research incorporating community engagement and citizen science.
Scientists at the German Cancer Research Center have discovered a protein called TXNIP that controls the aging process. TXNIP inhibits thioredoxin-1, an enzyme that protects DNA from oxidative stress and slows down aging processes.
Utah State University joins 33 institutions nationwide in the Howard Hughes Medical Institute's Inclusive Excellence initiative, aiming to engage all students in science regardless of background. The university will provide academic and social support for Native American students transferring from its Blanding campus.
University of Michigan researchers have made a breakthrough in treating Spinocerebellar ataxia type 3 (SCA3) using gene silencing technology. They successfully reduced mutant RNA levels without toxic effects, offering hope for disease-slowing therapy.
Researchers have identified a genetic variation associated with an increased risk of developing neuromyelitis optica (NMO), a potentially fatal disease that blinds and paralyzes patients. The study, published in Nature Communications, may help scientists develop targeted treatments for NMO.
A study found that individuals who perceive vegetarianism as a threat to their way of life tend to exclude certain animal categories from their moral circle. Human supremacy beliefs and perceived vegetarianism threat both predicted the exclusion of fewer animals, with stronger human supremacy beliefs leading to broader exclusions.
Research reveals that people globally aspire for moderate levels of intelligence, health, and happiness, rather than maximum perfection. Participants from holistic cultures tend to rate lower ideal levels for individual traits compared to nonholistic cultures.
Atrial fibrillation, Australia's most common heart rhythm disorder, can be alleviated by losing weight and treating lifestyle factors. Obesity is a leading cause of stroke and heart failure, but research shows that reducing weight by 10% can reverse the progression of the disease.
Current understanding of human physiology and surgery in space is crucial for future astronauts. The review highlights novel pathologies that could arise from prolonged weightlessness and exposure to cosmic radiation, emphasizing the need for specialized training and medical preparedness.
A team of researchers at Cornell University has discovered 10-nanometer, individual, self-assembled dodecahedral structures that could have significant applications in mesoscale material assembly and medical diagnostics. The discovery was made using a combination of machine learning algorithms and cryogenic electron microscopy.
The Active Office and Classroom demonstrate a 'buildings as power stations' concept, generating more energy than they consume. This innovative design could slash fuel bills and reduce carbon emissions in UK offices.
A study published in Acta Paediatrica found that non-dairy drinks can lead to malnutrition, height and weight impairment, anaemia, and other health problems in infants. The alternative beverages, commonly based on almonds, chestnuts, rice, and soya, were consumed by 34 children who suffered medical complications between 2005 and 2015.
A scientist at Duke University outlines how the constructal law of evolution in nature predicts the natural evolution of social organizations into larger and more complex communities. By applying this principle, Bejan shows why humans naturally organize themselves into societies with hierarchical systems to access finite resources.
Replacing traditional crop-based feed with protein-rich microbes could decrease deforestation, greenhouse gas emissions, and nitrogen losses by over 5%. Microbial protein production is economically profitable and could have positive effects on animal growth performance.
Researchers developed a new model for comparative genomic analysis, revealing differences in gene regulation between primate species. The Phylogenetic Hidden Markov Gaussian Processes model provides insights into what makes a human a human and has implications for understanding evolution and certain diseases.
Researchers developed a new error-correction method for DNA barcodes, reducing errors from 10% to 0.5%, allowing for more ambitious medical research and larger-scale experiments. The FREE method enables accurate tracking of biological molecules, including cancerous tumors and drug candidates.
Research from the University of Basel found that people tend to view exclusion as unjust when someone is visibly different from the group. However, if the excluded person is not visibly different, onlookers often assume they have
Scientists found that microbial proteins could reduce cropland usage by 6% and nitrogen losses by 8% globally. Replacing up to 19% of animal feed with microbial proteins could lower greenhouse gas emissions by 7% by 2050.
A team of scientists developed a high-throughput approach to integrate laboratory experiments, literature data, and network analysis to study Huntington's disease. The approach revealed that changes in inflammation, cell architecture, and calcium signaling drove the disease forward, while counteracting these changes improved health.
Researchers at Texas Tech University Health Sciences Center identified a specific amino acid residue responsible for inverting potassium channel communication. The study paves the way for developing novel and safer therapeutic drugs to correct illnesses associated with potassium channel dysfunction.
UCI-led researchers developed a groundbreaking tissue implant to treat temporomandibular joint dysfunction (TMJ) defects, successfully testing it in a large animal model. The innovative approach involves isolating cartilage cells from rib tissue and using them to engineer new jaw disc cartilage.
A UNLV study reveals that iPad neck pain is a growing problem among Americans, particularly young adults and women. The study found that postures such as sitting without back support and using tablets while lying on the side or back significantly contribute to the condition.
A new report analyzes 30 years of economic and migration data, revealing that asylum seekers have a positive impact on host countries' economies. Asylum seekers take longer than migrants to have a positive effect but still contribute significantly to tax revenues and improve public finances.
Scientists at Tel Aviv University develop a laser beam that traps and moves particles in specific directions using Archimedes' screw-inspired technology. The rotation of the beam determines the direction of particle movement, overcoming a major challenge in laser optical trapping.
A new study finds that swamp sparrows create time-honored song traditions by faithfully copying the most popular songs, with some lasting hundreds of years. The birds' cultural conformity generates extremely stable traditions in their bird song, rivaling those of humans.
Researchers analyzed ancient tools found with a 5,300-year-old frozen mummy to understand the Copper Age mountain people's way of life. The study revealed that the tools were made from chert collected from distant outcrops, indicating long-distance cultural contacts.
A multidisciplinary team at UC Santa Barbara found that immediate responses to disasters like wildfires and floods can have unintended consequences. By prioritizing long-term planning and adaptation strategies, decisionmakers can mitigate the risks of climate change-mediated disasters.
A new study from the University of Kansas reviewed data from 22 preclinical studies and 14 clinical studies, finding no significant reduction in symptoms of anxiety in humans. However, researchers suggest that probiotics may have potential benefits for anxiety and cognitive issues in the future.
A Baylor University study found multiracial US congregations have nearly doubled, with 12% of all congregations now racially mixed. African-Americans are increasingly leading these churches, and the percentage of black members has risen to nearly a quarter.
Researchers developed a stochastic modeling method to evaluate wind power impact on power systems, considering extreme outliers and computational efficiency. The method enables quantitative risk assessment and contributes to improving power system reliability and economic efficiency.
Researchers have developed a dual-therapy approach that combines brain-computer interface and functional electrical stimulation to boost motor recovery in stroke victims. The study found significant improvements in arm mobility among patients who received the treatment, with some scores exceeding twice those of control group patients.
A new study found a hitherto unknown error in the transport of glutamine between astrocytes and neurons in mice with Huntington's disease. The researchers believe this area holds potential for developing a future treatment.
Researchers at Purdue University have discovered a way to manipulate the interaction between paired and lined-up electrons in semiconductors. This finding has potential implications for electronic devices and quantum computing, as it allows for the tuning of electron-electron interactions and the control of phase transitions.
A massive Martian dust storm has engulfed the planet, prompting NASA's Opportunity rover to suspend science operations. However, Curiosity remains largely unaffected due to its nuclear-powered battery. The storm has grown to a 'planet-encircling' size, with atmospheric haze blocking sunlight at Gale Crater.
A new study found that most gates installed at abandoned mine entrances do not impede bat usage, with species adapting over time. Factors like elevation, portal area, and bat agility influenced bat behavior around gates.
The Global Precipitation Measurement mission captured extreme rainfall rates of up to 3.5 inches per hour in the northwestern Gulf of Mexico. Heavy flooding is expected along the coast of Texas into Louisiana, with a high risk of rip currents and minor coastal flooding.
A recent study published in Clinical Transplantation found that carefully-selected older adults over 60 years old pose minimal risks for living kidney donation. The research suggests that accepting more older donors can expand the donor pool, making a previously perceived high-risk group accessible.