The Dapagliflozin Effect on CardiovascuLAR Events - Thrombolysis in Myocardial Infarction 58 trial found that dapagliflozin markedly reduced the risk of hospitalization for heart failure and progression of renal disease, with benefits seen across the study population.
The REDUCE-IT trial found that icosapent ethyl reduced the risk of death due to cardiovascular causes, heart attack, and stroke by 25%, including a 20% reduction in death and 31% reduction in heart attack. This may set a new standard for patients with elevated triglycerides and increased cardiovascular risk despite statin therapy.
A new study of over 174,000 patients found that being treated with too much medication for hypothyroidism can lead to an increased risk of atrial fibrillation and stroke. The research suggests that the optimal healthy range of free thyroxine (fT4) levels may need to be reconsidered.
A three-year study found that children with autism improved in various skills, including social interaction and vocal skills, when taught alongside typically developing peers. The results suggest that mainstream pre-schools can provide suitable environments for supporting children with autism.
The VITAL study found that omega-3 fatty acids reduced the risk of heart attacks, particularly among African American participants. Vitamin D supplements may also lower cancer deaths over time, with a significant 25% reduction in mortality rates observed after two years of treatment.
A new study reveals that insects can transport pollen from one continent to another, enabling the mixing of plant species across vast distances. By analyzing the DNA sequences in this pollen, researchers were able to identify 157 species of plants from Africa and Europe.
Leading researchers urge government intervention to phase out organophosphates, citing evidence of lower IQs and difficulties with learning in children exposed prenatally. The review calls for reduced exposures through monitoring, education, and alternative pest-control measures.
A team of researchers at UC Davis has developed a new method to estimate the biological sex of human skeletal remains based on protein traces from teeth. This method uses sensitive mass spectrometry to measure proteins and can be used alongside existing techniques.
Researchers at the University of Edinburgh developed a cost-effective method to create high-performance energy devices and diagnostic tests using nanoparticles. The electrospinning technique, which produces nanofibres with high surface area, has been successfully tested in fuel cell applications.
A new oral drug significantly reduced menstrual bleeding in over 90% of premenopausal women with fibroid tumors. Elagolix also prevented estrogen-deficiency induced side effects like hot flashes and bone loss when prescribed with hormone therapy.
A new study analyzing one million years of precipitation history has found that the South Asian Monsoon is more complex than previously thought. The research team discovered that warming in the southern hemisphere and moisture transport across the equator play a crucial role in the monsoon's wind and precipitation patterns.
By eliminating redundant data, researchers have developed a technique that reduces the amount of information needed for accurate predictions. This approach has been successfully applied to various applications, including soil quality prediction, healthcare, and environmental studies.
Researchers at Ruhr-University Bochum have identified the proton transfer pathway in [FeFe]-hydrogenases, a crucial step for efficient hydrogen production. The study reveals that amino acids with no function can shut down hydrogenase activity, and provides valuable insights into the molecular mechanism of proton transfer.
A multidisciplinary team at Salk Institute will investigate mechanisms underlying Alzheimer's disease and aging-related cognitive decline using cutting-edge methods and machine-learning algorithms. The goal is to identify new targets for therapeutic research and biomarkers of early stage cognitive decline.
A recent UK-wide study found that solar panels experience a 25% power loss due to hot spots, which are more prevalent in Northern England. Hotspots were found to be caused by localized temperature increases and can lead to permanent damage.
A new study published in Neurology found that the antidepressant fluoxetine showed no benefit in treating acute flaccid myelitis, a rare condition causing paralysis in children. Researchers analyzed data from 56 children with the illness and found no improvement in muscle strength among those who received fluoxetine.
Researchers from the University of Barcelona used chironomid subfossils to reconstruct Holocene temperatures in the Iberian Peninsula, showing a rise in temperatures during the Holocene Climate Optimum and a decline after its onset. The study provides a promising tool for understanding climate evolution and natural changes.
Researchers have observed a powerful outflow of hydrogen gas from the Small Magellanic Cloud, indicating it may eventually stop forming new stars. The discovery provides insight into the evolution of galaxies and the potential source of gas for the enormous Magellanic Stream surrounding the Milky Way.
A UCSF study found that community choir participation reduced loneliness and increased interest in life among older adults, but did not improve cognition or physical function. The program, Community of Voices, engaged adults aged 60+ cognitively, physically, and socially through weekly group choir sessions.
A study analyzed over 100,000 Yelp reviews to identify key themes in emergency department and urgent care center ratings. Emergency departments received high marks for bedside manner but low marks for speed of care, while urgent care centers excelled in ease of prescription refills but struggled with patient confidence.
Researchers found that mitochondrial DNA influences cellular metabolism and susceptibility to metabolic diseases. Switching mitochondrial genetic backgrounds in mice showed significant impacts on adiposity, whole body metabolism, and nuclear gene expression.
A new study by Bocconi University's Gianmarco Ottaviano and colleagues identifies resource misallocation as a major cause of the productivity slowdown. Misallocation is stronger within industries and geographical areas, making it essential to implement policies promoting reallocation from less productive to more productive firms.
Researchers have identified a flat band area in graphene that is a prerequisite for superconductivity, but requires further assistance to achieve. The discovery uses high-resolution angle-resolved photoemission spectroscopy (ARPES) and could lead to controlled band structure manipulation.
Researchers at Purdue University have developed a new flexible, transparent biopatch that can deliver exact doses of biomolecules directly into cells, expanding observational opportunities. The patch, which is minimally invasive, can also treat cancerous tissue, making it a potential breakthrough in healthcare.
Meetings can provide creative thinking, problem-solving, and idea generation when done correctly. Researchers recommend preparing for meeting success, using technology to analyze behaviors, and improving post-meeting follow-up to enhance team outcomes.
The world's population is expected to be larger, heavier and eat more by 2050 due to population growth and changes in eating habits. According to researchers, an average adult today requires 6.1% more energy than in 1975, leading to increased food demand.
A recent study published in Springer's journal Behavioral Ecology and Sociobiology found that freshwater turtle hatchlings use the sun as their primary navigational cue. When released into a circular field arena with simulated daylight six hours earlier than usual, the turtles shifted their course by approximately 90 degrees.
A study published in Psychosomatic Medicine found that recent bereavement is associated with increased levels of inflammation and cardiovascular illness risk. Sleep disturbances exacerbated the negative effects of grief, highlighting the importance of addressing sleep issues in post-loss health interventions.
Scientists at EPFL have found that half of luminal epithelial breast cells express estrogen receptor at low levels, affecting cell function and cancer development. The estrogen receptor plays a biphasic role in breast cell growth and inhibition during pregnancy.
Researchers discovered small populations of T cells expressing functional SAP at normal levels in patients with XLP1, potentially modifying disease severity. This finding suggests gene therapy or adoptive cellular therapy could be effective treatments for the disease.
A new set of generic competencies has been established by ESCMID to guide healthcare professionals in using antibiotics responsibly. The competencies cover three main areas: antimicrobial prescribing, diagnosing infections, and stewardship. This framework aims to harmonize approaches to antibiotic use across Europe.
Scientists have proposed an innovative method to create custom-made mirror molecules for analysis by inducing rotationally-induced chirality in symmetric-top molecules. This technique could enhance insight into the workings of nature and pave the way for new materials and methods.
Researchers analyzed mountain glaciers using satellite imagery and found that 4.4% of the glacier surface is covered in debris, with uneven distribution towards poles and steep mountain regions. The study provides a basis for future modeling of debris impact on ice and can inform monitoring efforts to mitigate effects on water resources.
A portable and affordable mobile diagnostic tool utilizing nanotechnology can detect HIV viruses from a single drop of blood. The device offers high detection precision and is suitable for individuals with limited access to medical care.
Scientists at Institute for Basic Science achieved a breakthrough in shielding quantum properties by packing two atoms together, protecting fragile states 20 times longer than one atom. This development enables the exploration of single atoms as quantum bits for future information processing.
A new study by researchers at ICES and St. Michael's Hospital found that women with one severe maternal mortality (SMM) condition were 20 times more likely to die than those without any SMM conditions, with risks increasing exponentially with the number of SMM conditions.
Researchers uncovered unprecedented details about the ancestry of people in Central and South America, revealing a key link between Clovis culture-associated individuals and the oldest inhabitants of Chile, Brazil, and Belize. A continent-wide population replacement began at least 9,000 years ago, reshaping how researchers view Early H...
New research suggests that infant girls fed soy formula are more likely to develop severe menstrual pain as young adults. Women who had ever been fed soy formula as babies were 50% more likely to have experienced moderate or severe menstrual discomfort between the ages of 18 and 22.
Scientists developed a new method to produce nanodiamonds and silicon carbide with defined defects, utilizing neutron irradiation in nuclear reactors. This approach enables the efficient production of rare nanomaterials for medical applications, including cancer diagnostics.
A saliva-based RNA panel and algorithm can differentiate children with autism from non-autistic peers with 85% accuracy. This test could improve early diagnosis, enabling earlier intensive behavioral therapy to improve symptoms.
Four Jefferson Lab-affiliated scientists have been elected as Fellow of the American Physical Society, a prestigious honor recognizing their significant contributions to nuclear physics. Cynthia Keppel's fellowship honors her broad impact in fundamental nuclear science and applications of nuclear technology.
A new study found that focused ultrasound thalamotomy improves quality of life in people with medication-resistant Parkinson's disease. The procedure showed significant and sustained benefits in functional disability and overall well-being.
Researchers found shared genetic factors between Alzheimer's disease and high blood lipid levels, suggesting potential for early diagnosis and targeted therapies. The study analyzed 1.5 million individuals and identified specific DNA variants that increase the risk of developing both conditions.
Researchers solved a 125-year-old brain mystery by discovering that perineuronal nets modulate electrical impulses in the brain. Without these structures, inhibitory neurons fire too slowly, leading to seizures. The findings have implications for various forms of acquired epilepsy and may lead to new treatments.
A study has found that rising atmospheric CO2 levels could disrupt the sedimentary balance of beach-dune systems, leading to erosion and increased flooding risks. The research suggests that by 2100, sediment accumulation at the base of Mediterranean dunes could fall by 31%, putting beaches like San Giovanni in Sardinia at risk.
A study published in Applied and Environmental Microbiology found that antibiotic-resistant E. coli bacteria in wild giraffes most likely come from anthropogenic sources. The research suggests that young giraffes are more likely to harbor resistant bacteria, potentially due to competition between strains.
A University of Pennsylvania School of Nursing article highlights how nurses understand factors leading to firearm violence and investigate ways to prevent it. The research identifies priority areas for nursing science to address this public health problem.
A study by Kanazawa University found that rural tourism has a positive impact on rural communities in Japan, preserving landscapes and creating jobs for older people. However, the industry faces challenges such as small income generation and seasonality, which threaten its long-term sustainability.
About 10% of men and 7% of women reported significant levels of distress and social impairment due to compulsive sexual behavior disorder. A survey study found that 2,325 adults between 18-50 experienced distress and impairment associated with difficulty controlling their sexual feelings, urges, and behaviors.
The Q.Link.X project funds a quantum repeater development to overcome transmission link limitations in optical fiber-based quantum communication, aiming for distances of up to ten or 100 kilometers.
Researchers transformed a Martian sunrise photo into a two-minute piece of music, with quiet harmonies and brighter sounds created by the sun disk. The work showcases image sonification's potential in analyzing planet surfaces and atmospheres, as well as health science applications.
A new study found that individuals who excessively post selfies on social media exhibit a significant increase in narcissistic traits, including grandiose exhibitionism and entitlement. This effect is particularly pronounced among those who primarily use visual platforms like Facebook.
A study by the University of Sheffield reveals that high levels of nitrogen dioxide pollution damage plant defenses, leading to poor growth in herbivorous insects. The research suggests that urban green spaces play a modest role in removing pollutants from the air.
Tropical Cyclone Alcide's winds have dropped to 80 mph as it lingers just northeast of Madagascar in the Southern Indian Ocean. The storm is expected to curve northward and pass near the northern point of Madagascar over several days.
Researchers found that farmers have adapted to climate change by adjusting planting practices and using longer maturing varieties. This shift has increased maize yield trends by 28% since 1981, but it remains unclear if these benefits will be maintained in a hotter environment.
Researchers have developed a miniature pacemaker design that enables less painful, faster recovery times, and reduced medical costs. The innovative approach uses a tiny incision to implant the device, cutting down on surgical time.
Researchers from Skoltech, MIPT and Samara State Technical University improved the evolutionary crystal structure prediction algorithm USPEX, generating initial structures 3 times faster, thanks to a novel random structure generator based on topological types of crystal structures.
For the first time, researchers have found plastic microfibers in the stool of wild South American fur seals on Guafo Island. The discovery suggests that scat analysis could be an efficient way to monitor environmental levels of microfibers and microplastics.
A study published in Complementary Therapies in Medicine found that face massage rollers increased facial skin blood flow by up to 25% after just five minutes. Long-term use also improved the vasodilatory response, suggesting a potential mechanism behind its benefits.
Researchers found that small ParkScore improvements lead to increased physical exercise among residents, with cities like Minneapolis and San Francisco ranking high. The study suggests that investing in park infrastructure can positively impact public health, with a collective effect of improved fitness and well-being.