Scientists at Newcastle University have made a significant discovery in treating childhood brain cancer, identifying a chromosome signature that can predict patient outcomes and tailor treatment to individual needs. This breakthrough aims to reduce toxicity and side effects while maintaining cure rates.
The ORA project investigates the connection between citizens and parliament, essential for democracy. The team, led by Professor Thomas Zittel, will analyze legislators' behaviors to understand if geographic ties offer an alternative to collective representation by political parties.
A new study by Lund University researchers has found that the Inaccessible Island rail, also known as Atlantisia, flew to its island habitat from South America around 1.5 million years ago. This discovery contradicts a previous theory suggesting the bird's inability to fly was an ancient trait.
A recent study found that young plasma has a protective effect on liver damage caused by ischemia reperfusion injury in experimental animals. The study's results demonstrate the therapeutic potential of blood from young animals to prevent age-related phenomena.
A NASA team is experimenting with ultrafast lasers to weld dissimilar materials, including exotic glasses and metals. The goal is to develop new manufacturing techniques that could benefit spaceflight instruments.
A new MIT study finds that every five-year delay in reducing mercury emissions results in a 14% decrease in the effectiveness of policy measures, with remote regions suffering most. The researchers used modeling to estimate legacy emissions and found that delays lead to an accumulation of toxic mercury in the environment.
A study by researchers at Florida Atlantic University and Cleveland State University found a positive association between not having paid sick leave and reporting financial worry. Workers without paid sick leave were more likely to worry about short-term financial issues like housing expenses, as well as long-term financial issues such...
A study by Penn State researchers highlights inadequate food safety practices among farmers market vendors, with key areas of concern including hand washing, personal hygiene, and cross-contamination. The researchers recommend a tailored training program to address these issues and ensure safe food sales in Pennsylvania.
A study by ISGlobal and partners found that prenatal exposure to malaria significantly alters a newborn's innate immune response, particularly if the placenta is infected. This type of exposure may affect a baby's risk of developing malaria during their first year of life.
Women carrying rare breast cancer variants are more likely to develop interval breast cancers, which are often aggressive and lethal. The study found that these women have a higher risk of death from breast cancer compared to those with common mutations.
A two-part study by University of Oregon psychologist Marjorie Taylor found that 17% of children aged 8-12 create complex imaginary worlds, reflecting positive creativity, strong storytelling skills, and social connections. These 'paracosms' were often shared with friends, suggesting a social aspect to this childhood phenomenon.
A new visual analytics tool, Beagle, is being used by law enforcement agencies to trace email scammer networks and highlight critical links. Developed with data security company Agari, Beagle dramatically speeds up forensic email investigations.
Norse World is a new digital resource providing an index of foreign place names in Swedish and Danish literature from the Middle Ages. The tool enables researchers to study perceptions of the surrounding world in Medieval Scandinavian literature, exploring concepts of spatiality and gender.
Zebrafish models have been developed to study the intricate molecular pathways underlying mucosal melanomas. The research identified a previously unrecognized tumor suppressor, SPRED1, and its interplay with oncogene KIT. These findings hold promise for developing precision cancer therapies for this rare and aggressive form of melanoma.
A study published in Biological Psychiatry found that exposure to early life violence accelerates biological aging, including pubertal development, while deprivation-related adversity leads to delayed pubertal development. Children who experienced violence showed signs of accelerated epigenetic aging and increased symptoms of depression.
Researchers found that the Yangtze dams have reduced the distance of Chinese sturgeon migration by 1,175 kilometers, leading to delayed maturity and a decline in breeding activity. The environmental capacity of the spawning ground has also been reduced, contributing to the ongoing decline of the species.
Maria Goeppert Mayer's groundbreaking nuclear physics research at Argonne earned the lab a historic physics site designation. The 'shell' model of the atomic nucleus she developed remains the basis for modern understanding of nuclear structure.
The American Geriatrics Society defines 'healthy aging' as a broader, person-centered concept that prioritizes physical, mental, and social needs. The new definition emphasizes a lifespan approach to care, age-friendly concepts, and community engagement to promote health, safety, and independence in older adults.
Researchers discovered that cancer-causing papillomaviruses diverged from their common ancestors half a million years ago, coinciding with the split between Neanderthals and modern humans. The viruses adapted to specific host ecosystems and then coevolved with primates for at least 40 million years.
Chemists at Friedrich Schiller University Jena have discovered a previously unknown metabolic pathway in plankton that produces a key compound in the global sulfur cycle. This finding provides valuable information about the earth's sulfur cycle and has important implications for atmospheric and climatic models.
A new study suggests that heat-resistant enzymes like Cytochrome P450 can be designed for better and more cost-effective drug production. The enzyme's flexibility at high temperatures may lead to improved drugs for humans, producing them en masse and making them more cost-effective.
A study found that individuals with fear of missing out, internet addiction, and certain personality traits exhibit more extreme reactions to digital technology failures. People who are more neurotic and extroverted tend to have the most maladaptive responses when their devices stop working.
A recent cluster of cocaine-fentanyl overdoses highlights the need for more readily available testing strips to identify fentanyl in patients. The outbreak prompted a coordinated public health response, including law enforcement investigation and education of residents on the dangers of fentanyl.
A study published in the Journal of Thoracic Oncology found that elderly patients with limited-stage small cell lung cancer (LS-SCLC) can benefit from concurrent chemo-radiotherapy, similar to younger patients. The analysis showed comparable survival rates and toxicity between older and younger groups, providing robust evidence for tre...
Scientists have demonstrated a novel way to protect correlated photon states, opening a path to build robust entangled states for logic gates. This breakthrough uses silicon nanowires to create 'edge modes' that help guide and create these correlated states.
Researchers at Northwestern Medicine have successfully reprogrammed induced pluripotent stem cells into healthy uterine cells for potential treatment of endometriosis. The study marks a significant step towards treating the painful and persistent gynecological disease, which affects approximately 10% of women worldwide.
A new study found that Chinese adults' end-of-life care preferences vary based on whether they have children. Adults who lost their only child prefer specialized hospice or palliative care institutions, while those with children prefer family-based care at home.
A recent study revealed that robust reef-building corals possess a unique capacity to generate an essential amino acid, which may make them less susceptible to global warming-induced coral bleaching. This advantage allows robust corals to repair tissue and grow new tissue more efficiently than complex corals.
A research group from Kumamoto University discovered a new neurogenic mechanism responsible for brain development, revealing that Matrin-3 regulates the differentiation of neural stem cells into neurons. The absence of this protein causes disordered differentiation and collapse of brain layer structure.
The new guidelines review and update the 2013 European guidance for diagnosing and managing osteoporosis in postmenopausal women. Key findings include the importance of evaluating bone microstructure and using FRAX tools in fracture risk assessment, as well as the need for long-term dietary intakes and monitoring drug treatment.
Hurricane Oscar has transitioned into an extra-tropical low pressure area, characterized by a loss of tropical characteristics and poleward displacement. The storm is expected to bring winds and rain to Ireland over the weekend of Nov. 3 and 4.
Researchers have created a groundbreaking cellular atlas of the brain, revealing over 70 different types of neurons, their locations, and functions. This breakthrough technology allows for unprecedented insights into brain organization and behavior.
The discovery of human embryonic stem cells in 1998 revolutionized regenerative medicine, with 29 clinical trials underway globally. The field has grown exponentially, enabling large-scale production of pure cells for research, and nearly $1.43 billion spent on NIH stem cell research over the past 20 years.
Researchers discovered that a drug inhibiting glutamine metabolism improves certain immune cells' function while suppressing others. Inhibiting glutaminase activity protects against inflammation and disease in mouse models of various conditions.
Scientists at Ames Laboratory have discovered a new quantum criticality in a superconducting material, exhibiting a hedgehog spin-vortex crystal antiferromagnetic state without nematic transitions. This finding suggests that spin fluctuations are the primary driver of superconductivity.
The SQZ Biotechnologies platform has been shown to preserve key biological functions essential for cell therapies, unlike electroporation technology. This study highlights the superiority of SQZ in delivering target-specific immune responses and enabling scalable cell therapy development.
A new study published in Child Development found that a short-term family-centered prevention program can have enduring effects on brain network connections into young adulthood. The program improved self-regulation skills and parental emotional support, leading to fewer disruptive behavioral problems.
The Lyme Disease Biobank now accepts tissue donations from patients undergoing knee-replacements and similar surgeries, as well as patients who die with Lyme disease. Researchers aim to explore the ability of Lyme bacteria to invade tissues and organs, leading to medical breakthroughs in diagnosis and treatment.
Researchers found Mycobacterium bacteria thriving in US showerheads, particularly in areas with high rates of lung disease. The study also revealed geographic patterns and material-specific influences on bacterial growth.
A new study by Virginia Tech Transportation Institute (VTTI) analyzed child restraint laws nationwide and found that 34 states exempt taxis and for-hire vehicles from child restraint requirements. The study also revealed that up to half of parents report not providing appropriate child safety seats while riding in ride-share vehicles, ...
Researchers have developed flexible, semi-transparent films that block electromagnetic interference while allowing light to pass through. The films, made from a combination of carbon nanotubes and MXene, demonstrate high strength, flexibility, and conductivity, making them suitable for use in devices with display screens.
Researchers found that immigrants quickly lose native microbes and acquire alien microbes more common in European-American people, resulting in a loss of gut microbiota diversity. This Westernization is associated with greater obesity and is compounded across generations.
Researchers found that reproductive stem cells boost production of non-coding RNA elements to suppress jumping gene activity and activate DNA repair processes, enabling normal egg development. Temperature influences sterility in fruit flies, with a specific temperature range controlling jumping gene invasion intensity.
Research reveals that healthy plants host diverse fungi and oomycetes in roots, but a balanced bacterial community prevents illness; certain bacteria promote plant health by limiting fungal growth.
Tropical Storm Yutu produced heavy rainfall over Luzon in the Philippines, but analysis from NASA's Global Precipitation Measurement mission showed little rainfall near its center of circulation. Heavy rainfall was found in powerful storms northwest and southeast of Yutu's center, with rates exceeding 183 mm/hour.
The NIH BRAIN Initiative Cell Census Network has released its first data set, featuring the molecular identities of over 1.3 million mouse brain cells and anatomical data from 300 brains. This comprehensive characterization aims to integrate molecular, anatomical, and functional data on cell types in mice, humans, and non-human primates.
The Russian Foundation for Basic Research is supporting research projects in various fields, including electrochemistry, photonics, and archaeology, through grants of up to 20 million rubles per year. Established researchers will receive funding for their interdisciplinary fundamental research projects.
A comprehensive Australian study examined the global impact of suicide prevention approaches in young people and found that youth-specific interventions can be effective in reducing self-harm and suicidal thinking. The study highlights the importance of investing in evidence-based interventions and identifying gaps in current approaches.
Researchers discovered that breastfeeding for over six months lowers the risk of non-alcoholic fatty liver disease (NAFLD) in mothers. Women who breastfed one or more children for longer periods had a lower risk compared to those who did not breastfeed or breastfed for under one month.
A new study suggests that reducing US coal emissions through biomass and carbon capture can create 22,000 new jobs in the forestry and transportation sectors. This approach would retain 40,000 existing coal industry jobs while mitigating global warming below 2°C.
Researchers found kanglemycins, a group of natural antibiotics similar to rifamycin, which can target mutated RNAPs. These antibiotics may have emerged as a result of evolutionary pressures in nature, providing a potential solution to the rising problem of antibiotic resistance.
A groundbreaking new study aims to understand the human immune system's response to influenza by analyzing gene regulation, microbiome influence, and other factors. Researchers will take comprehensive measurements from healthy participants who receive a standard influenza vaccination.
Scientists have studied vanadium dioxide's ultrafast phase transition, revealing that atomic motions are unpredictable and occur independently of each other. This discovery lays the groundwork for advances in computer hardware and could lead to breakthroughs in controlling material behavior.
A new paper urges creation of a coordinating global body to assure neutral evaluation of gene editing's benefits and risks. The technologies have breathtaking promise but also profound concerns about unintended consequences, requiring careful review and inclusion of local communities.
A study reveals lymph nodes as reservoirs of persistent tuberculosis infection, where the bacteria can persist for extended periods. This finding has significant implications for tuberculosis treatment and patient outcomes.
Researchers discovered that the brain's 'posture cells' can predict an animal's position in three-dimensional space. These neurons, found in the posterior parietal cortex (PPC) and frontal motor cortex (M2), encode body posture and spatial awareness in mice.
A new report suggests that addressing chronic diseases like diabetes could save tens of billions of dollars in healthcare costs annually. Proper nutrition therapy and exercise can effectively cause remission of Type 2 diabetes, with a one percent decrease in HbA1c levels resulting in significant savings.
Using a dataset of over 500 single-stranded RNA viruses, researchers developed a model that can predict animal reservoirs and arthropod vectors directly from viral genome sequences. This approach enables faster evaluation than existing methods, which often require years, and could aid in rapid response to emerging infectious diseases.
Researchers found that people with Alzheimer's disease who were treated with diabetes drugs showed fewer markers of the disease, including abnormal microvasculature and gene expressions. The study suggests targeting the brain's capillary system could have beneficial effects in Alzheimer's patients, opening opportunities for new therapies.
Scientists have discovered a way to detect the early signs of atherosclerosis, leading to blocked arteries, by analyzing changes in blood vessel cells. The study used single-cell RNA-sequencing and lineage labelling to identify unusual cells that express stem cell genes, which could help diagnose and treat cardiovascular diseases.