A case of tick-borne relapsing fever was reported in Sonora, Mexico, where the disease gets little attention. The patient's symptoms improved with doxycycline treatment, and spirochetes were detected in her blood, supporting the identification of an endemic focus for the disease.
SourcePLOS·JournalPLOS Neglected Tropical Diseases·DateApr 11, 2019
A team of scientists has mapped a molecular complex that could aid in the development of better medications with fewer side effects for osteoporosis and cancer. The findings provide insight into how PTH1R interacts with key messengers to regulate calcium levels.
SourceVan Andel Research Institute·JournalScience·DateApr 11, 2019
Researchers have developed a new method for transporting medicine through the body, using a sliding molecule that can jump between polymers to deliver medication to specific organs. Laboratory tests confirm the model's effectiveness in delivering molecules to gel-like materials.
SourceUniversity of Southern Denmark·JournalNature Chemistry·DateApr 11, 2019
A new international protected area target is necessary to effectively conserve biodiversity, according to a study published in Science. The current target has led to perverse outcomes, with nations unable to account for real progress.
SourceUniversity of Queensland·JournalScience·DateApr 11, 2019
Apple iPhone 17 Pro
Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
Researchers from Chalmers University of Technology have created the world's fastest hydrogen sensor, capable of detecting extremely small amounts of hydrogen in the air in under a second. The sensor works by using an optical phenomenon called plasmon, which changes color when hydrogen levels change.
SourceChalmers University of Technology·JournalNature Materials·DateApr 11, 2019
Coral reefs surrounding Palmyra Atoll in the Pacific recovered dramatically after a 2015 bleaching event, with less than 10% dying. Imaging software and 3D structuring helped scientists monitor coral growth and decline over time.
SourceUniversity of California - San Diego·JournalCoral Reefs·DateApr 11, 2019
Researchers developed a novel cell model of aging-related colon cancer risk by combining genetic and epigenetic factors. The model shows that epigenetic changes are essential for cancer initiation, and can be used to assess cancer risk in human lab-grown cells.
SourceJohns Hopkins Medicine·JournalCancer Cell·DateApr 11, 2019
Researchers at DOE's Ames Laboratory developed a new microscopy approach to image gel nanocomposites in their natural state, providing insights into their assembly and properties. The technique allows for the observation of nanoparticles within gels, which shows promise in creating materials with unique optical properties.
SourceDOE/Ames National Laboratory·JournalMicron·DateApr 11, 2019
Scientists found no long-lasting, major differences between astronaut Scott Kelly's epigenome and his twin brother Mark's after a year in space. The study suggests that research on additional astronauts may help predict medical risks on long space journeys.
SourceJohns Hopkins Medicine·JournalScience·DateApr 11, 2019
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C)
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C) keeps Macs, tablets, and meters powered during extended observing runs and remote surveys.
A study published in the Clinical Journal of the American Society of Nephrology found that pruritus affects 24% of patients with non-dialysis chronic kidney disease. Patients with pruritus reported poorer mental and physical quality of life, depression, and restless sleep.
SourceAmerican Society of Nephrology·JournalClinical Journal of the American Society of Nephrology·DateApr 11, 2019
A new study by Michigan State University found that the state's graduation requirements for math are leading to more students taking and passing advanced math courses. This policy change is also resulting in higher college enrollment rates, particularly among low-income students.
SourceMichigan State University·JournalEducational Evaluation and Policy Analysis·DateApr 11, 2019
A new study investigates the Auger effect in aromatic hydrocarbons, revealing that molecules with pi electrons have a lower double ionization threshold. This finding favors Auger decay over saturated hydrocarbons, with potential applications in cancer treatment and atomic identification.
SourceSpringer·JournalThe European Physical Journal D·DateApr 11, 2019
The NASA Twin Study has provided a comprehensive multi-omics view of the human body's response to long-term space flight. The study found increased collagen proteins in urine, correlating with vascular remodeling during space flight.
SourceUniversity of California - San Diego·JournalScience·DateApr 11, 2019
Researchers propose introducing strategic interventions to address climate change by identifying sensitive intervention points in socio-economic systems. Such interventions could amplify into radical change, potentially averting a climate catastrophe.
SourceAmerican Association for the Advancement of Science (AAAS)·JournalScience·DateApr 11, 2019
Apple AirPods Pro (2nd Generation, USB-C)
Apple AirPods Pro (2nd Generation, USB-C) provide clear calls and strong noise reduction for interviews, conferences, and noisy field environments.
Researchers found a link between prostate medicines and increased risk of type 2 diabetes in men taking 5-alpha-reductase inhibitors. Men on these medications should be monitored for warning signs of diabetes and have their prescriptions adjusted if necessary.
SourceUniversity of Edinburgh·JournalThe BMJ·DateApr 11, 2019
Scientists at Rice and Northwestern universities have developed a method to image and characterize 2D borophene crystals, which can exhibit unique lattice configurations that determine their characteristics. The research could help manufacturers incorporate borophene into products with desirable electronic, thermal, optical properties.
SourceRice University·JournalNature Communications·DateApr 11, 2019
A new report finds that Arkansas PROMISE has succeeded in increasing services, training, employment, and income for participants. The program increased the likelihood of participating youth having a paid job and decreased their reliance on Social Security payments.
A team of biologists has discovered new rules governing cell decision-making in genetics, revealing how genes are activated under specific conditions. The study found that a protein called Zelda strengthens Dorsal activity, allowing cells to make decisions about gene activation based on their environment.
SourceNew York University·JournalCurrent Biology·DateApr 11, 2019
Patients with acute coronary syndromes can return to work in two to three months, but one in four quit after a year. Psychological factors like lack of confidence, depression, and anxiety are significant predictors of failure. Attending cardiac rehabilitation and gradual reintegration into the workplace can help patients succeed.
SourceEuropean Society of Cardiology·JournalEuropean Journal of Preventive Cardiology·DateApr 11, 2019
Apple MacBook Pro 14-inch (M4 Pro)
Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.
Brown University researchers capture the first 'snapshot' of two proteins involved in delivering a bacterial stress-response master regulator to the cell's recycling machinery. The discovery sheds light on the importance of the regulation for antibiotic resistance, disease-causing bacteria, and biofilm development.
SourceBrown University·JournalGenes & Development·DateApr 11, 2019
A new study found substantial variation in vaccine coverage within countries, with some areas having less than 25% coverage. The study provides insights for nations' health ministers to identify where to improve vaccine delivery systems and tailor strategies to reach unvaccinated children.
SourceInstitute for Health Metrics and Evaluation·JournalThe Lancet·DateApr 11, 2019
Researchers found that ketamine restores dendritic spines in the prefrontal cortex of mice with depression-like behavior. Healthy dendritic spines are crucial for long-term antidepressant effects, suggesting interventions to enhance their survival may be helpful in sustaining ketamine's benefits.
SourceAmerican Association for the Advancement of Science (AAAS)·JournalScience·DateApr 11, 2019
Long-term spaceflight causes significant changes to gene expression, immune system, and DNA repair systems. The study provides insights into the effects of prolonged space travel on astronaut health and may help scientists develop treatments or prevention strategies.
SourceWeill Cornell Medicine·JournalScience·DateApr 11, 2019
Researchers create statistical tool for stylometric analysis using graphs, finding that individuality manifests itself in surprisingly small number of words. The method identifies authors correctly in almost 90% of cases, requiring only 10-12 words to be traced in English texts.
SourceThe Henryk Niewodniczanski Institute of Nuclear Physics Polish Academy of Sciences·JournalInformation Sciences·DateApr 11, 2019
SAMSUNG T9 Portable SSD 2TB
SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
Physicists at the University of Bath have developed a flexible way to synthesize novel nanomaterials, including Tungsten Disulphide -TMDs. The process allows for tunable materials with potential applications in optics and sensors.
The CheckMate 451 study found that maintenance immunotherapy did not prolong overall survival in patients with extensive-stage small cell lung cancer. However, the study suggested that patients who received early maintenance therapy may have longer progression-free survival rates.
SourceEuropean Society for Medical Oncology·JournalAnnals of Oncology·DateApr 11, 2019
Researchers found that rat brain activates same cells when observing others' pain as when experiencing pain itself, indicating shared empathy mechanism. The cingulate cortex region is responsible for this emotional sharing, and suppressing its activity can prevent rats from freezing in response to others' distress.
SourceNetherlands Institute for Neuroscience - KNAW·JournalCurrent Biology·DateApr 11, 2019
A collection of 4,000 fossils from the Texas Gulf Coast 11-12 million years ago reveals a diverse ecosystem with species like elephants, rhinos, and alligators. The fossils also include horse breeds, camels, and several carnivores.
SourceUniversity of Texas at Austin·JournalPalaeontologia Electronica·DateApr 11, 2019
A global review of water reallocation from rural to urban regions found that 69 cities receive significant amounts of reallocated water, mainly driven by North America and Asia's growing populations. The practice is expected to rise further, with 2.5 billion more urban dwellers projected by 2050.
SourceUniversity of Oxford·JournalEnvironmental Research Letters·DateApr 11, 2019
GQ GMC-500Plus Geiger Counter
GQ GMC-500Plus Geiger Counter logs beta, gamma, and X-ray levels for environmental monitoring, training labs, and safety demonstrations.
Scientists at Scripps Research have identified small molecules that prevent structural changes to proteins causing the disease. These molecules bind to and stabilize immunoglobulin light chain proteins, preventing misfolding and forming toxic plaques.
SourceScripps Research Institute·JournalProceedings of the National Academy of Sciences·DateApr 11, 2019
Researchers have identified chromogranin A as a key regulator of cardiotoxic and antitumor activities of Doxorubicin, a widely used cancer drug. Monitoring plasma levels of CgA before and after chemotherapy may provide prognostic information on drug-related cardiotoxicity.
SourceFederation of American Societies for Experimental Biology·JournalThe FASEB Journal·DateApr 11, 2019
Researchers identified special brain cells that allow animals to reconstruct their social partner's state of mind and predict their intentions. Dysfunction in these 'simulation neurons' may contribute to social cognition difficulties in conditions like autism and social anxiety.
A new study published in Proceedings of the National Academy of Sciences found that stress increases fear-promoting brain regions while reducing fear-reducing ones. This shift can be mimicked by increasing norepinephrine release, potentially leading to more effective treatments for PTSD.
SourceTexas A&M University·JournalProceedings of the National Academy of Sciences·DateApr 11, 2019
Researchers developed DASH materials that exhibit metabolism, self-assembly, and organization - key traits of life. The biomaterial autonomously emerges from nanoscale building blocks, grows, and decays, allowing it to perpetuate dynamic processes.
SourceCornell University·JournalScience Robotics·DateApr 11, 2019
GoPro HERO13 Black
GoPro HERO13 Black records stabilized 5.3K video for instrument deployments, field notes, and outreach, even in harsh weather and underwater conditions.
A study by Penn State researchers estimates that the US government lost up to $37.8 billion in tax revenue between 2000 and 2016 due to opioid-related employment loss. The state of Pennsylvania was among the hardest hit, with approximately $638.2 million lost in income and sales tax.
Researchers at CNIO have discovered biomarkers in surgically treated patients' fluid that reveal specific mutations and help determine cancer recurrence risk. The new liquid biopsy technique may enable earlier detection and more targeted treatment for melanoma patients.
SourceCentro Nacional de Investigaciones Oncológicas (CNIO)·JournalJournal of Experimental Medicine·DateApr 11, 2019
The NASA Twins Study found changes in gene expression and metabolite alterations that support the potential health effects of long-duration spaceflight on astronauts. The study also suggests that human health can be mostly sustained over a year-long space mission, with targeted countermeasures needed for future Mars missions.
SourceUniversity of Texas Health Science Center at San Antonio·JournalScience·DateApr 11, 2019
A team of UT Southwestern researchers has created a groundbreaking two-hit model to combat HFpEF, a type of heart failure with no effective treatments. By combining high-fat diets with blood pressure-raising drugs, they replicated the human condition and provided an accurate biological picture that can advance treatment development.
SourceUT Southwestern Medical Center·JournalNature·DateApr 11, 2019
A recent study found that contamination of privacy curtains with multidrug-resistant organisms (MDROs) is a common problem in healthcare facilities globally. The researchers discovered that patient colonisation with MRSA and VRE was associated with curtain contamination, highlighting the potential for MDRO transmission to patients.
SourceEuropean Society of Clinical Microbiology and Infectious Diseases·DateApr 11, 2019
Sky & Telescope Pocket Sky Atlas, 2nd Edition
Sky & Telescope Pocket Sky Atlas, 2nd Edition is a durable star atlas for planning sessions, identifying targets, and teaching celestial navigation.
Scientists at UC Berkeley discovered that mountain formation in the tropics triggers global cooling, resulting in ice caps. The team found that volcanic arc-continent collisions in the tropics expose rocks with high CO2-absorbing capacity, cooling the planet.
SourceUniversity of California - Berkeley·JournalScience·DateApr 11, 2019
Scientists have discovered the native structure of AMPA receptors in rodent models, which may lead to new insights into neurodegenerative diseases such as Alzheimer's. The research could provide novel approaches for therapies by understanding how these receptors differ in people with devastating diseases.
SourceOregon Health & Science University·JournalScience·DateApr 11, 2019
Scientists identified a molecular driver of glioblastoma, a highly aggressive and treatment-resistant brain cancer, by analyzing cell-by-cell genetic data. Researchers found that reprogramming primitive oligodendrocyte progenitors into stem-like cells plays a key role in glioma initiation and progression.
SourceCincinnati Children's Hospital Medical Center·JournalCell Stem Cell·DateApr 11, 2019
A comprehensive profile of B cells in rheumatoid arthritis reveals their involvement in the disease's progression. Researchers identified two specific differences in B cells that contribute to the condition, including the inclusion of interleukin 15 receptor subunit alpha and high levels of amphiregulin.
SourceUniversity of Houston·JournalArthritis & Rheumatology·DateApr 11, 2019
Researchers at the University of Oregon have successfully created artificial atoms in white graphene, which can generate single photons and potentially lead to breakthroughs in all-optical quantum computing. The discovery enables the scalable fabrication of artificial atoms onto a microchip, working in air and at room temperature.
Kestrel 3000 Pocket Weather Meter
Kestrel 3000 Pocket Weather Meter measures wind, temperature, and humidity in real time for site assessments, aviation checks, and safety briefings.
A DNA barcoding study has identified a group of cryptic species among the Warszewitsch's frog, found in Costa Rica and Panama. This finding highlights the need for modern DNA tools to study rapidly declining animal groups like amphibians.
A study of over 4,000 young adults in the UK found that nearly 20% had nonalcoholic fatty liver disease, and one in 40 had advanced fibrosis. The condition is linked to obesity, diabetes, and hyperlipidaemia, highlighting the need for greater public health awareness.
SourceSpink Health·JournalJournal of Hepatology·DateApr 11, 2019
A new study found that HIV-infected individuals have a longer lifespan of white blood cells called neutrophils, which may contribute to intestinal inflammation. Lactobacillus bacteria, commonly used in probiotics, could be an effective therapeutic strategy to reduce neutrophil-driven inflammation.
A new study reveals that consumers are actively choosing to visit certain places to confront their feelings, grief or worries in a safe space. Therapeutic Servicescapes like Lourdes' marketplace offer emotional expression and vulnerability acceptance, leading to improved well-being.
SourceLancaster University·JournalJournal of Consumer Research·DateApr 11, 2019
Sony Alpha a7 IV (Body Only)
Sony Alpha a7 IV (Body Only) delivers reliable low-light performance and rugged build for astrophotography, lab documentation, and field expeditions.
Researchers Inanc Senocak and Cheng-Nian Xiao uncover fluid instabilities in the Prandtl model for katabatic slope flows, a complex phenomenon crucial for reliable weather predictions. Their findings suggest that dynamic stability cannot be determined by a single dimensionless parameter alone.
SourceUniversity of Pittsburgh·JournalJournal of Fluid Mechanics·DateApr 11, 2019
Scientists found that NIPSNAP proteins function as 'eat me' signals on damaged mitochondria, recruiting cellular machinery for mitophagy. In a zebrafish model, animals lacking NIPSNAP1 protein died within five days due to impaired mitochondrial clearance, highlighting its importance in maintaining dopaminergic neurons.
Researchers found diphtheria, tetanus, and whooping cough vaccination levels in Nigeria, DRC, Ethiopia, Mozambique, and Cambodia below the 80% threshold. Targeted campaigns can improve immunization service delivery, especially in areas with poor routine immunization coverage.
SourceUniversity of Southampton·JournalNature Communications·DateApr 11, 2019
Researchers develop new microscope, SCATTIRSTORM, to study cellulase and plant cell wall dynamics for more efficient biofuel production. The microscope enables high temporal resolution and spatial resolution, allowing for detailed understanding of enzyme activity.
DJI Air 3 (RC-N2)
DJI Air 3 (RC-N2) captures 4K mapping passes and environmental surveys with dual cameras, long flight time, and omnidirectional obstacle sensing.
A large-scale study of mouse mutants identified 38 new genes involved in hearing loss, revealing molecular pathways and regulatory processes. The findings provide a rich source of therapeutic targets for restoring hearing and suggest therapies may need to be directed at common molecular pathways.
SourceWellcome Trust Sanger Institute·JournalPLOS Biology·DateApr 11, 2019
The NASA Twins Study found no significant health differences for astronaut Scott Kelly after spending nearly a year in orbit. However, changes were observed in his DNA methylation and gene expression, particularly related to the immune system, which may persist after his return to Earth.
SourceAmerican Association for the Advancement of Science (AAAS)·JournalScience·DateApr 11, 2019
Katia Vega, a UC Davis design professor, has received the Johnson & Johnson WiSTEM2D Scholars Award for her innovative work in integrating technology into wearable cosmetics. The $150,000 grant provides three years of mentorship and aims to fuel development of female STEM leaders.
A majority of reusable tourniquets inspected contained microbes that could compromise patient safety and care quality. The most prevalent contaminant microorganism was coagulase-negative staphylococci, found on 441 of the analysed tourniquets.
SourceEuropean Society of Clinical Microbiology and Infectious Diseases·DateApr 11, 2019
Rigol DP832 Triple-Output Bench Power Supply
Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.
A new study led by Murray Cox has found that modern Papuans carry hundreds of gene variants from two deeply divergent Denisovan lineages, separated for 350,000 years. The research reveals a complex history of interbreeding between modern humans and archaic hominins in Island Southeast Asia.
SourceMax Planck Institute for Evolutionary Anthropology·JournalCell·DateApr 11, 2019
A new report by the Centers for Disease Control and Prevention shows a significant increase in autism prevalence in New Jersey, with the rate rising 43 percent from 2010 to 2014. The state's autism rate is now one in 35 among 4-year-olds, significantly higher than the national average of 1.7 percent.
Researchers developed a biophotonic technique that uses ultraviolet and red light irradiation to eliminate bacteria and viruses from organs before transplantation. The method significantly reduced viral load in eight patients and completely eliminated the virus in two others.
SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalNature Communications·DateApr 11, 2019
Research scientists have uncovered hidden diversity within a type of frog found only in the Seychelles, showing that each island has its own distinct lineage. The study reveals four species of sooglossid frogs are threatened by climate change and disease, including a lethal fungus known as chytrid.
SourceUniversity of Kent·JournalBiological Journal of the Linnean Society·DateApr 11, 2019
Researchers developed a new method to alleviate chronic inflammatory disease by inducing mitophagy and removing damaged mitochondria. The treatment with choline kinase inhibitors reduced NLRP3 inflammasome activation and prevented inflammation in mice with genetic diseases such as Muckle-Well Syndrome.
SourceUniversity of California - San Diego·JournalCell Metabolism·DateApr 11, 2019
Celestron NexStar 8SE Computerized Telescope
Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.
The study identifies four major problems with the United Nation's Aichi Target 11, including perverse outcomes and ineffective conservation efforts. The authors argue that outcome-based targets for protected areas are needed to achieve biodiversity goals.
SourceWildlife Conservation Society·JournalScience·DateApr 11, 2019
A large-scale screen of mouse mutants revealed 38 new genes involved in hearing loss, including those related to metabolic pathways and regulatory processes. These findings provide a rich source of therapeutic targets for the restoration of hearing.
A recent study discovered that the nascent polypeptide-associated complex (NAC) plays a key role in preventing protein aggregation associated with neurodegenerative diseases. NAC suppresses PolyQ aggregation and enhances organismal fitness, according to tests using animal models such as C. elegans.
SourceUniversity of Konstanz·JournalMolecular Cell·DateApr 11, 2019
A financial model developed by Stevens Institute of Technology assistant professor Hamed Ghoddusi explores the effects of the Tax Cuts and Jobs Act on homebuying. The SALT deduction cap has a predictable impact on property tax collections, particularly in high-income states.
SourceStevens Institute of Technology·JournalJournal of Economic Dynamics and Control·DateApr 11, 2019
Research reveals that chronic diseases significantly decrease mobility in older adults without them realizing it, affecting physical activity levels. Exercise therapies tailored to the type of disease can improve physical functioning and independent living possibilities.
SourceUniversity of Jyväskylä - Jyväskylän yliopisto·JournalAnnals of Medicine·DateApr 11, 2019
AmScope B120C-5M Compound Microscope
AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.
A study by researchers at the University of York found that costly external NHS hospital inspections do not lead to improvements in quality of care. Rates of falls and pressure ulcers improved before inspections, but slowed afterwards. The authors suggest a less resource-intensive approach to reduce costs and burden on staff.
SourceUniversity of York·JournalJournal of Health Services Research & Policy·DateApr 11, 2019
A large-scale genome-wide association study has identified 14 new variants associated with the development of kidney stones, including four linked to obesity and high blood uric acid levels. The findings may be useful for predicting individuals' risk of developing kidney stones and identifying new targets for prevention and treatment.
SourceAmerican Society of Nephrology·JournalJournal of the American Society of Nephrology·DateApr 11, 2019
Researchers found that Ebola survivors exhibit memory immune responses, including specific T cells against the virus, persisting over 2 years after infection. These findings could help develop more effective vaccines by boosting key immune cells needed for long-lasting protective immunity.
SourceEuropean Society of Clinical Microbiology and Infectious Diseases·DateApr 11, 2019
The American Institute of Aeronautics and Astronautics has announced the winners of its 2019 Technical Excellence in Aerospace Awards. The awards recognize pioneering work in various fields of aerospace engineering, including aerodynamics, aircraft design, fluid dynamics, and more.
SourceAmerican Institute of Aeronautics and Astronautics·DateApr 11, 2019
New research from Tepper School of Business finds that forcing employees to interact with unfamiliar colleagues in open work spaces encourages exploration, leading to improved financial performance and new product ideas.
SourceCarnegie Mellon University·JournalJournal of information and organizational sciences·DateApr 11, 2019
Fluke 87V Industrial Digital Multimeter
Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.
The Microbicide Trials Network is conducting a study to assess the acceptability, tolerability, and adherence of three rectal delivery methods: placebo inserts, suppositories, and douches. The study aims to understand individual preferences for HIV prevention products.
Researchers at USC and UCLA have developed a new method to prevent damage to the jaw, a side effect of cancer treatment. The approach uses a different BP compound that can be used locally in the mouth to push the drug from the jawbone while leaving the useful drug undisturbed.
SourceUniversity of Southern California·JournalBone·DateApr 11, 2019
Researchers at Boston Children's Hospital and MIT have developed nanobodies that can target the tumor micro-environment, allowing for more effective treatment of solid tumors. The nanobodies were tested in mouse models of melanoma and colon cancer, showing promising results in slowing tumor growth and improving survival rates.
SourceBoston Children's Hospital·JournalProceedings of the National Academy of Sciences·DateApr 11, 2019
Researchers found evidence of gene sharing among human-associated bacteria, with 30% higher rates than natural occurrence. Gene transfer occurred between closely related organisms and across tissue boundaries, facilitating innovation at the microbe level.
SourceUniversity of Illinois at Urbana-Champaign, News Bureau·JournalBiology Letters·DateApr 11, 2019
Nikon Monarch 5 8x42 Binoculars
Nikon Monarch 5 8x42 Binoculars deliver bright, sharp views for wildlife surveys, eclipse chases, and quick star-field scans at dark sites.
Researchers found that serum AKR1B10 levels were significantly associated with advanced liver fibrosis stages, particularly stage 4. The protein's origin was confirmed via immunohistochemical staining, and its combination with WFA(+)-M2BP showed high sensitivity and specificity for predicting NASH fibrosis and life-threatening events.
SourceKanazawa University·JournalJournal of Gastroenterology·DateApr 11, 2019
Researchers created salt blends using calcium and potassium chloride to reduce sodium chloride content without compromising flavor. The optimal blend achieved a balance of 96.4% sodium chloride and 3.6% replacement salts, increasing the possibility of gradual reductions in salt consumption.
SourceWashington State University·JournalJournal of Food Science·DateApr 11, 2019
In a two-year greenhouse experiment, plants pollinated by bumblebees without herbivory evolved more attractive flowers, while those with herbivory had higher concentrations of defensive toxic metabolites. Plants developed a tendency to spontaneously self-pollinate when damaged by caterpillars.
Researchers found that Hirschsprung disease shares common genetic mechanisms with complex disorders like schizophrenia and autism. The study identified key genes, cellular mechanisms, and molecular targets for personalized treatment.
SourceNYU Langone Health / NYU Grossman School of Medicine·JournalNew England Journal of Medicine·DateApr 11, 2019
Apple iPad Pro 11-inch (M4)
Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.
Scientists from the University of East Anglia have discovered a unique group of oil-eating bacteria in the Mariana Trench, which is located approximately 11,000 meters below sea level. The bacteria are capable of consuming hydrocarbons similar to those found in crude oil and natural gas.
SourceUniversity of East Anglia·JournalMicrobiome·DateApr 11, 2019
Researchers developed a method to distinguish tumor margins from healthy tissues using bright spot analysis in confocal microscopy. The technique showed promise in differentiating glioblastoma tumors from surrounding brain tissue and has potential applications for tumors without 5-ALA-derived red fluorescence.
SourceKanazawa University·JournalPhotodiagnosis and Photodynamic Therapy·DateApr 11, 2019
Researchers from University of Kansas will analyze genomic data from ancient and contemporary Aleutian Islanders to understand their evolutionary and cultural history. The study aims to uncover the genetic influence of Russian colonization and how the unique environment prompted biological adaptations.
The €50 million MOBILISE-D project aims to develop a system using small sensors to monitor mobility and assess health. It will enable personalized healthcare, predictive diagnosis, and improved treatment for conditions like COPD, Parkinson's disease, and multiple sclerosis.
Physicists simulate infinite quantum particles to understand macroscopic scale behavior, reconciling quantum mechanics and classical mechanics. This approach allows for the calculation of physical entities like the second virial coefficient, enabling robust predictions.
SourceSpringer·JournalEPJ Techniques and Instrumentation·DateApr 11, 2019
Sky-Watcher EQ6-R Pro Equatorial Mount
Sky-Watcher EQ6-R Pro Equatorial Mount provides precise tracking capacity for deep-sky imaging rigs during long astrophotography sessions.
Research reveals an unusual three-year spike in late-season surface melting on the Larsen C ice shelf, caused by foehn winds. This could lead to a denser and less stable ice shelf, potentially putting it at risk of similar fractures as nearby Larsen A and B shelves.
SourceUniversity of Maryland·JournalGeophysical Research Letters·DateApr 11, 2019
Researchers at Technical University of Munich discovered that plant cells recognize bacteria through small fatty acid molecules, rather than complex molecular compounds. This finding could lead to breeding or genetically engineering plants with improved immune responses and increased resistance to pathogens.
SourceTechnical University of Munich (TUM)·JournalScience·DateApr 11, 2019
Researchers found ketamine restores functional connectivity and ensemble activity of neurons and eliminates depression-related behaviors. Dendritic spine formation is crucial for maintaining remission, but its slow process may indicate that it's a consequence of ketamine-induced rescue of prefrontal cortex circuit activity.
SourceNIH/National Institute of Mental Health·JournalScience·DateApr 11, 2019
Researchers have discovered a novel biosynthesis pathway for aryl polyene pigments in bacteria, produced via a unique complex of proteins. These pigments exhibit anti-oxidative properties similar to carotenoids but are formed differently.
SourceGoethe University Frankfurt·JournalJournal of the American Chemical Society·DateApr 11, 2019
Apple Watch Series 11 (GPS, 46mm)
Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.
The NASA Twins Study found that Scott Kelly's telomeres in white blood cells got longer while in space, contradicting initial expectations. This could mean a higher risk for accelerated aging and age-related diseases, including cardiovascular disease and cancer.
SourceColorado State University·JournalScience·DateApr 11, 2019
Research from the NASA Twins Study found that extended spaceflight alters the ratio of two major categories of bacteria in the gut microbiome, but not its diversity. The study's findings could help protect astronauts' and space tourists' microbiomes during long bouts of space travel.
SourceNorthwestern University·JournalScience·DateApr 11, 2019
A study of 400,000 camera-trap records from 36 mammal species on three continents found that tropical mammals respond to changing local temperatures and other species nearby. Temperatures did not increase drastically overall during the study period, but micro habitat use changed over time due to temperature fluctuations.
SourceRice University·JournalGlobal Ecology and Biogeography·DateApr 11, 2019
A new CRISPR-Cas3 system allows for efficient genome editing in human cells, erasing long stretches of DNA from targeted sites. This technology holds promise for treating viral diseases such as herpes simplex and hepatitis B, which are major public health threats.
SourceCornell University·JournalMolecular Cell·DateApr 11, 2019
An interdisciplinary research group at KIT is developing an agile production system that autonomously adapts to changing product specifications using multi-modal sensors and artificial intelligence. The system aims to improve remanufacturing processes, enabling the reuse of electric motors from the automotive industry.
SourceKarlsruher Institut für Technologie (KIT)·DateApr 11, 2019
CalDigit TS4 Thunderbolt 4 Dock
CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.
A new algorithm developed by Stanford researchers can accurately identify individuals at risk of familial hypercholesterolemia (FH), a cholesterol-raising genetic disease that increases the risk of early and fatal heart problems. The algorithm, trained on data from over 200 FH patients, correctly flagged 88% of cases in testing runs.
SourceStanford Medicine·Journalnpj Digital Medicine·DateApr 11, 2019
Scientists from Michigan Technological University have successfully created 2D gold quantum dots that can be customized at the atomic level on boron nitride nanotubes. This breakthrough enables the creation of tunable semiconducting materials with potential applications in future electronics and quantum computing.
SourceMichigan Technological University·JournalACS Nano·DateApr 11, 2019
Two large real-world studies confirm the efficacy of glecaprevir/pibrentasvir in a broad range of individuals with HCV infection, including those with comorbidities. The treatment showed significant improvements in physical and mental well-being, with high sustained virological response rates.
SourceSpink Health·JournalJournal of Hepatology·DateApr 11, 2019
Psychologists have found that facial expressions can influence emotional feelings, with smiling making people feel happier and scowling making them feel angrier. The study combined data from nearly 50 years of research involving over 11,000 participants.
SourceUniversity of Tennessee at Knoxville·JournalPsychological Bulletin·DateApr 11, 2019
Davis Instruments Vantage Pro2 Weather Station
Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.
Researchers developed an AI agent that can generate natural language explanations in real-time, making it more relatable and trustworthy for non-experts. Participants preferred human-generated rationales over AI-generated ones, but AI-generated responses were close seconds.
A new root algorithm developed by Beth Drewniak improves the Energy Exascale Earth System Model's ability to simulate vegetation growth and respond to changes in resources. The dynamic root model addresses both water uptake and nitrogen allocation, enabling plants to thrive in varying environmental conditions.
SourceDOE/Argonne National Laboratory·JournalJournal of Advances in Modeling Earth Systems·DateApr 11, 2019
The University of Delaware team created poly(aryl piperidinium) polymers for hydroxide exchange membranes, achieving record power density and stability. This breakthrough enables the development of more efficient and cost-effective fuel cells for eco-friendly vehicles.
SourceUniversity of Delaware·JournalNature Energy·DateApr 11, 2019
Research reveals that over-the-counter throat medications containing topical antibiotics can contribute to antibiotic resistance in certain bacteria species. The study found that some products were not sufficiently concentrated to prevent bacterial growth, enabling resistance development.
SourceEuropean Society of Clinical Microbiology and Infectious Diseases·DateApr 11, 2019
Researchers found that sensory cortex signals can cause mice to stop actions, while motor cortex signals can enhance performance. This discovery sheds light on abnormal signaling in neurological and psychiatric disorders.
SourceRutgers University·JournalCurrent Biology·DateApr 11, 2019
Aranet4 Home CO2 Monitor
Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.
Researchers found commercially available fish preparations for skin prick testing varied greatly in allergen content, leading to false negative results and potential life-threatening consequences. The team is working on advanced diagnostics and therapy for seafood allergy.
Researchers found a small male advantage in mental rotation skills among children aged six to eight, with no difference detected among preschoolers. The study suggests that other factors may be more important than biology in driving the gender gap in spatial skills during childhood.
SourceEmory Health Sciences·JournalPsychological Bulletin·DateApr 11, 2019
The Kidney Health Atlas reveals that 14.5 million people will have end-stage kidney disease by 2030, yet only 5.4 million will receive treatment due to economic and social factors. The atlas highlights significant gaps in kidney care globally, particularly in low-income countries.
Researchers from CNIO have successfully removed advanced pancreatic ductal adenocarcinoma (PDA) in animal models through combined inhibition of EGFR and c-RAF kinase. This breakthrough has shown significant promise for developing new cancer treatments.
SourceCentro Nacional de Investigaciones Oncológicas (CNIO)·JournalCancer Cell·DateApr 11, 2019
Researchers found that male fruit flies produce fewer proteins in their seminal fluid when females are without competition, leading to health disadvantages for the females. In contrast, polygamous males with no competition can manipulate females through protein receipt, increasing their own reproductive success.
SourceUniversity of Münster·JournalProceedings of the National Academy of Sciences·DateApr 11, 2019
Garmin GPSMAP 67i with inReach
Garmin GPSMAP 67i with inReach provides rugged GNSS navigation, satellite messaging, and SOS for backcountry geology and climate field teams.
A new study finds that abundant herbivores diminish plants' attractiveness to pollinators but increase energy spent on producing offspring through autonomous self-pollination. Plants rapidly evolve defensive traits, like toxic compounds, to ward off herbivores while maintaining floral displays attractive to pollinators.
SourceAmerican Association for the Advancement of Science (AAAS)·JournalScience·DateApr 11, 2019
A study by Max Planck Institute found that pension gap between rich and poor in Germany has grown significantly over the past 20 years. Life expectancy of poor men is diverging more from rich men, with those receiving high retirement benefits living 19 years longer on average compared to low-income men.
SourceMax-Planck-Gesellschaft·JournalJournal of Epidemiology and Community Health·DateApr 11, 2019
Chronic post-surgical pain affects 10% of patients, often requiring higher levels of opioids that can lead to tolerance and opioid-induced hyperalgesia. Opioid prescribing for surgery patients poses a challenge, with increases in misuse and abuse linked to inadequate pain management.
The New England Journal of Medicine advocates for standardized care in treating Ebola patients. Recent innovations, such as the Cube System, offer improved patient-centered care through continuous observation and accessibility.
SourceLiverpool School of Tropical Medicine·JournalNew England Journal of Medicine·DateApr 11, 2019
Researchers at Virginia Tech use drones and AI to complement human searchers, analyzing historical data from over 50,000 lost person scenarios. The system aims to provide large-scale data for better decision-making, addressing niche problems in the search process.
Creality K1 Max 3D Printer
Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.
A nationwide survey found that 33.3% of cancer patients used complementary and alternative medicines, with herbal supplements being the most common. Many participants did not disclose their CAM use due to lack of physician inquiry or perceived unnecessary information.
A UK study found that only one-third of patients with suspected urinary tract infections (UTIs) actually have evidence of the infection. In reality, nearly all patients receive antibiotics, which contributes to antimicrobial resistance. The study suggests implementing antimicrobial stewardship initiatives could reduce unnecessary antib...
SourceEuropean Society of Clinical Microbiology and Infectious Diseases·DateApr 11, 2019
Researchers found evidence of historic marine life in Alaskan permafrost, revealing that the Beaufort Sea was not completely frozen over during the late Ice Age. This discovery improves scientists' ability to reconstruct past Arctic sea-ice conditions and inform future climate strategies.
SourceHokkaido University·JournalEarth and Planetary Science Letters·DateApr 11, 2019
The Healthy Start program aims to address longstanding perinatal health disparities in Houston's most disadvantaged communities. The initiative will provide community-based services and health education to black women, their partners, and families to promote preconception care and behaviors that reduce risk.
The REHEAL Glove is a flexible wound dressing that provides negative pressure therapy and allows early motion therapy during healing. It has successfully completed another key step on the road toward commercialization, earning national recognition for its potential to improve treatment of hand trauma.
Meta Quest 3 512GB
Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.
An international team uses seismic data from glacial earthquakes to study calving and its impact on ice sheet mass loss. This breakthrough in environmental seismology reveals that calving resulted in the shedding of 370 gigatonnes of ice into the Arctic Ocean between 1993 and 2013.
A longitudinal study found a correlation between ceramide levels, body mass index, and disease progression in MS patients. Individuals with higher ceramide levels experienced greater loss of motor skills and more brain injury over two years.
SourceAdvanced Science Research Center, GC/CUNY·JournalEBioMedicine·DateApr 11, 2019
Leonardo da Vinci made penetrating insights into how the brain functions through exquisite drawings and scientific rigor. His pioneering experiments, including a study of the olfactory nerve and ventricles, challenged earlier authorities and introduced new methods.
Dr. Constance Nathanson, a professor at Columbia University's Mailman School of Public Health, has been awarded the Guggenheim Foundation Fellowship to explore health crises and institutional change in France. Her research compares how HIV contamination of the blood supply played out in France versus the US.
SourceColumbia University's Mailman School of Public Health·DateApr 11, 2019
One-third of cancer patients use complementary and alternative medicines such as meditation, yoga, acupuncture, and herbal supplements. Many patients do not disclose their use to doctors due to lack of knowledge or perceived need for disclosure.
SourceUT Southwestern Medical Center·JournalJAMA Oncology·DateApr 11, 2019
A recent study published in Science found that a year-long mission to the International Space Station has a small but significant impact on the gut microbiome. The researchers discovered that the ratio of two dominant phyla of bacteria shifted during flight, but returned to normal after Scott Kelly's return to Earth.
SourceUniversity of Illinois Chicago·JournalScience·DateApr 11, 2019
A new study of ancient DNA fragments in modern Papuans and Islanders suggests two distinct Denisovan lineages separated for hundreds of thousands of years, one potentially a new archaic hominin species. The findings highlight the importance of considering underrepresented regions in genome data to improve scientific interpretations.
Researchers at McMaster University have discovered a unique subset of cells, called human pluripotent founder cells, that appear to signal how surrounding cells will develop and grow. These 'kingpin' cells are found in primates but not in mice, suggesting they may play a key role in understanding cancerous tumours.
A study proposes a new target for protected areas based on biodiversity outcomes, addressing issues with current targets that focus on quantity rather than quality. The new approach involves systematic monitoring of global sites of biodiversity significance to determine the effectiveness of management practices.
SourceInternational Institute for Applied Systems Analysis·JournalScience·DateApr 11, 2019
Researchers have developed a new label-free imaging technique that reveals the dynamic movement of chromatin in eukaryotic cells just before cell death. The study found that cells experience a 'burst' of activity, known as cellular paroxysm, which is thought to play a role in the earliest stages of cell death.
SourceNorthwestern University·JournalNature Communications·DateApr 11, 2019
Researchers have achieved record-breaking accuracy with an optical clock, setting a new standard for cesium-referenced measurements. The high accuracy of optical clocks could support advances in timing systems used in navigation and communication systems, enabling more precise measurements of physical phenomena not yet fully understood.