Scientists at Technical University of Denmark have discovered 9 genes that can be silenced to increase protein production in engineered yeast cells by 2.2-fold. This breakthrough method has significant implications for industries producing biopharmaceutical proteins and industrial enzymes.
A new study from the University of Colorado Denver estimates that education has an economic value twice as large as lifetime earnings for better health and longevity. Adults with a high school degree live longer and with less disability, worth $693,000 among men and $757,000 among women.
Researchers at the University of Hamburg and DESY have developed a 3D printing process for transparent and mechanically flexible electronic circuits using silver nanowires. The technology enables the production of printable light-emitting diodes, solar cells, and tools with integrated circuits.
A new study reveals that 75% of the Atlantic Coast from North Carolina to Central Florida will be highly vulnerable to erosion and inundation from rising tides by 2030. The region has seen a 30% increase in highly vulnerable areas since 2000, with species like loggerhead and green sea turtles facing significant threats.
The red-neck phalarope population from Western Palearctic migrates over 10,000 km to Pacific Ocean and 6,000 km to Arabian Sea for winter, exhibiting a unique migratory divide. This phenomenon is attributed to the species' biogeographical history and can help identify global migratory patterns.
Researchers found that childhood oral infections, such as caries and periodontitis, are associated with increased risk of atherosclerosis and cardiovascular disease. A 27-year follow-up study showed that the more signs of oral infections present in childhood, the higher the risk for adulthood atherosclerosis.
Researchers at the La Jolla Institute for Immunology discovered that genetic deletion of TET2 and TET3 in mouse B cells impairs the generation of functional IgG antibodies, highlighting the critical role of epigenetic control in healthy immune cell function.
Scientists have traced a prehistoric eruption to the lesser-known volcano Campi Flegrei in Naples, which dated back 29,000 years. The research, published in Geology, used computer models and sediment cores to identify the ash layer's origin.
The National Institutes of Health has awarded a $2.7 million grant to the Leadership Alliance to support expanded mentoring opportunities for underrepresented groups in biomedical science. The grant will provide funding for workshops, research career development, and one-on-one mentoring for students and junior faculty from historicall...
Volcano seismologist Jacqueline Caplan-Auerbach studies Loihi's 1996 eruption for parallels to Kilauea's 2018 activity, suggesting a caldera collapse mechanism. Loihi's recent increase in seismicity may indicate magma replenishment, predicting Kilauea could be quiet for a decade before reactivating.
A new study by Concordia researcher Carly Ziter shows that extensive tree canopy cover in urban areas can dramatically reduce temperatures, making a significant difference even within a few city blocks. The study found that temperatures vary as much within the city as they do between the city and surrounding countryside.
Tropical Storm Lorna's maximum sustained winds reached 60 knots near April 26. The storm was forecast to strengthen into a hurricane and then begin transitioning into an extra-tropical cyclone by the weekend of April 27-28.
A new study reveals how little energy survives from surface ocean plants and animals, with diatoms providing a robust ecosystem at the seafloor. These heavy, dead diatoms form a food web that includes tubeworms, crabs, and other organisms living in a 'feast-or-famine' existence.
Researchers from Carnegie Mellon University have controlled the lifetime of gold nanoclusters' quantum states, extending it by three magnitudes. This breakthrough could improve solar cell and photocatalysis technologies, allowing for more efficient energy harvesting.
Researchers at RMIT University have developed a new technique to produce microscopic 3D images of tissue inside the body using existing optical fibre technology. This approach enables clinicians to examine living tissue in real-time, paving the way for minimally-invasive 3D optical biopsies.
A new vaccine approach could protect against pandemic flu by teaching the immune system to recognize the shared 'cone' portion of the flu virus, rather than just the seasonal 'scoop'. Researchers have shown early promising results in lab animals.
A new North Carolina State University study found that lionfish in the Atlantic and Pacific regions share genetic similarities, suggesting a population near Taiwan as the source of the invading species. The research also revealed that lionfish in the Atlantic exhibit rapid reproductive rates and voracious predation, devastating native ...
A new study from the Norwegian University of Science and Technology found that higher body mass index (BMI) is linked to an increased risk of developing psoriasis. The observational study analyzed data from over 750,000 individuals and found a 9% increase in risk for each whole BMI unit increase.
Researchers used CRISPR-Cas9 to engineer cassava plants resistant to viruses, but found mutated viruses that evolved resistance instead, threatening crop yields. The study warns of potential unintended consequences of gene-editing technology in agriculture.
Researchers aim to understand molecular mechanisms behind dilative cardiomyopathy (DCM) and hypertrophic cardiomyopathy (HCM), two leading causes of heart failure. The study seeks to identify key genes and proteins involved in these conditions.
Researchers have identified areas with persistent seismic signals caused by industrial processes using a dense sensor network spanning the US. The map, developed by Los Alamos National Laboratory, pinpoints prominent sources of industrial activity, including wind farms and large water pumping stations.
Scientists found contrasting latitudinal gradients in woody and herbaceous communities, with closely-related species in tropical rain forests and temperate grasslands. The study supports the view that different regions act as evolutionary cradles or museums, influencing diversity patterns.
Researchers from Henry Ford Health System demonstrated exosomes' ability to suppress chemotherapy-induced peripheral neuropathy and enhance the anti-tumor effects of platinum drugs. Exosome treatment significantly reduced tumor size by 80-91% compared to platinum drugs alone.
Messier 75 is a globular cluster located approximately 67,000 light-years away from Earth in the Sagittarius constellation. The cluster features an enormous core with about 400,000 stars, making it one of the most densely populated clusters ever discovered.
A pilot program investigates human-animal interactions (HAIs) in reducing suffering of children with cancer undergoing debilitating treatments. Children are randomly assigned to a group receiving usual care or a group receiving HAI plus therapy dog visits.
Researchers found signs of ground failure, including slumped road ramps and liquefaction, in the aftermath of the 2018 Anchorage earthquake. The study suggests that shaking from the quake did not reactivate past landslides, likely due to its short duration.
Abnormal necroptosis function contributes to cancer cell survival and multiple sclerosis, Parkinson's disease. Controlling necroptosis may lead to new treatments for these diseases.
Researchers describe violacein's mechanism of action against bacteria, including its ability to kill drug-resistant pathogens and disrupt membrane organization. The study's findings suggest violacein's potential as a target for future antimicrobial research.
The University of Maryland Medical Center successfully transplanted a kidney into a patient using an unmanned aircraft, demonstrating the potential of UAS for faster and safer organ deliveries. This breakthrough could improve outcomes for patients in need of organ transplants, particularly those in rural or geographically remote areas.
MIT engineers designed tiny robots that use magnetic fields to push nanoparticles out of blood vessels and into tumors, improving drug delivery efficiency. The robots create fluid currents that drag nanoparticles along, overcoming one major obstacle to targeted nanoparticle delivery.
A specially designed health intervention improved healthy eating and exercise habits among South African youth, with effects lasting at least 4.5 years. The study found that participants in the intervention had greater odds of meeting guidelines for healthy eating and physical activity than the control group.
Researchers have successfully created 'humanized' antibodies that can neutralize human herpesvirus 6B (HHV-6B) infection. The antibodies target the gH/gL/gQ1/gQ2 protein complex and CD134 receptor, essential for HHV-6B infection.
Researchers have identified over 600 small earthquakes between magnitude 2.0 and 3.8 in Ohio, Pennsylvania, West Virginia, Oklahoma, and Texas, linked to fracking operations. The study reveals that the depth of the well is a significant factor in predicting likelihood of seismicity.
The Children's National Hospital NICU implemented a quality-improvement project that reduced unintended extubations by 60% over 10 years through standardized taping methods, bedside review of events, and reducing chest X-rays. The project saved an estimated $1.5 million per year and improved patient safety.
Adult mouse models of SYNGAP1 disorder show improvement in measures of seizure and memory after gene repair, suggesting potential for treatment at any stage of life. The study offers a path to measure the effectiveness of potential medications or therapies.
Researchers at Ruhr-University Bochum developed a method to increase bioelectrode stability by operating under an oxygen-free environment. This approach effectively extends the device's lifespan and brings photobiodevices closer to efficient energy conversion.
Tropical Cyclone Kenneth made landfall in northern Mozambique with maximum wind speeds of 140 miles per hour, causing significant rainfall and flooding. The storm's remnants continue to linger over the region, generating strong winds and severe thunderstorms.
A Princeton-led research team reconstructed ocean nitrogen levels from 70 million years ago to 30 million years ago, showing a significant increase in oxygen after the India-Asia collision. This finding reveals that plate tectonics had a major impact on ocean chemistry and life conditions.
A new study from Lund University found that Indian women are younger and leaner when developing gestational diabetes compared to Swedish women. The researchers identified a gene linked to increased risk in Swedish women but protective effects in Indian women.
Researchers are investigating whether metamaterial concept can be scaled up to city size to reduce earthquake damage. Simulations show that structures act as resonators, plucking energy from Rayleigh waves, and optimal building arrangement could reduce damage by decreasing height radially inward.
Researchers discovered that reports of human cases of West Nile virus were delayed by two to 14 weeks between illness onset and confirmation. Accurate and reliable forecasts are possible using real-time reports of human and mosquito testing positive for the virus.
Researchers used digital footprints to determine personality traits and matched them with images, finding that extroverts preferred simple images featuring people, while open-minded individuals favored cool colors. The study showed that personalized ads could increase consumer interest and purchase intentions.
A recent genome-wide association study found that childhood-onset asthma is associated with nearly three times as many genes as adult-onset asthma. The study identified 61 independent asthma-related genes, with most being specific to childhood onset. The findings suggest different mechanisms cause the inception of asthma in childhood c...
Scientists warn of ocean acidification's impact on marine life, habitat degradation and biodiversity loss due to rising CO2 levels, threatening ecosystem services and human livelihoods.
A new study reveals that Nobel Prize winners in economics exhibit two distinct life cycles of creativity. Conceptual innovators tend to peak in their mid-20s, while experimental innovators reach their creative peak in their mid-50s. This research suggests that the type of approach taken by an individual plays a significant role in dete...
A new SGLT2 inhibitor medication has been shown to significantly slow the progression of chronic kidney disease (CKD) in patients with diabetes. The CREDENCE trial demonstrated a 34% reduction in the risk of end-stage kidney disease, as well as improved cardiovascular outcomes.
A large Swedish study found a strong association between high blood polychlorinated biphenyl (PCB) levels and premature death. The study, which followed over 1,000 seniors for 10 years, showed that individuals with the highest PCB levels had a 50% excess mortality rate from cardiovascular disease.
The LIMPRINT study found that chronic edema significantly impacts health-related quality of life in patients, particularly those with leg swelling. The condition is often neglected and difficult to treat, affecting a large portion of the population.
Researchers found that exposure to violence impairs the ability to place trust in individuals who are likely to be helpful, leading to increased disciplinary infractions. The study suggests that this cognitive disruption can have long-lasting effects on social functioning and stability.
Researchers found that when participants were unsure whether a profile was written by a human or an algorithm, they distrusted the one they believed to be machine-generated. The study suggests designing AI communication tools with transparency and trustworthiness in mind can improve user experience.
Research by NYU Steinhardt professor Susannah Levi found that children with high language skills can easily understand speech from familiar speakers and strangers with similar accents. However, children with lower language skills struggle to process unfamiliar voices.
A longitudinal study found that changes in individuals with head injuries were associated with increases in self-reported and violent offending among adolescents and early adults. Head injury is five to eight times more common among individuals involved with the criminal-justice system than in the general population.
A pilot study at the Medical University of South Carolina found that peppermint oil improved symptoms of esophagus disorders, including difficulty swallowing and non-cardiac chest pain. The study showed a significant improvement in symptoms among patients with spastic disorders of the esophagus.
Researchers developed a new class of anti-ice surfaces called low interfacial toughness (LIT) materials, which can shed ice from large areas with minimal force. LIT materials work by causing cracks to form easily beneath the ice, allowing it to readily dislodge.