Scientists have successfully reduced bovine leukemia virus levels in cows by combining an immune checkpoint inhibitor with an enzyme inhibitor, showing promise for controlling other diseases in cattle. The treatment also demonstrated antiviral effects in BLV-infected animals with high viral loads.
Researchers at Yale University have developed a promising combination immune therapy to dramatically reduce the recurrence of genital herpes. The prime-and-pull strategy involves a vaccine and medicated cream that work together to block the virus from spreading.
Researchers compared outcomes in patients with and without HIV who received stage-appropriate cancer treatment after a cancer diagnosis at age 65. The study found no significant difference in overall survival between the two groups, suggesting that age alone may not be a determining factor in cancer treatment outcomes.
A recent study published in The Lancet found an AI model can identify patients with intermittent atrial fibrillation using a 10-second ECG test. The technology achieved an overall accuracy of 83% and has the potential to aid doctors investigating unexplained strokes or heart failure.
A study by World Vision and Columbia University found that Child Friendly Spaces have a positive impact on younger children's well-being but little effect on older children. Implementing high-quality spaces with local context is crucial for reducing protection concerns and promoting development.
Hurricane Erick is a small storm with strong thunderstorms holding on, but expected to significantly weaken as it passes Hawaii. The National Hurricane Center forecasts Erick's winds will be 200 miles from the islands.
A new pilot study led by Boston University School of Public Health found that a youth empowerment program targeting one dietary behavior - replacing sugar-sweetened beverages with water - could prevent obesity risk among youths. The program, which had Worchester youths create their own narratives about reducing sugary drink consumption...
Researchers have developed a powerful new brain imaging tool called Voltron, which lets them track neuron activity in living animals more precisely and for longer periods than before. Voltron uses an ultra-bright synthetic dye and a specially engineered protein to detect neural signals throughout the brain.
Researchers from Peter the Great Saint-Petersburg Polytechnic University found a substance that reduces the negative effect of mutations in genes related to neuronal contact formation. The discovery suggests promising compounds for anti-Alzheimer's drugs.
The Los Angeles County Board of Supervisors approved a five-year, $170 million annual funding agreement to provide patient care services and physician medical education at LAC+USC Medical Center. This historic partnership continues the institution's commitment to providing superior medical care to the Los Angeles County community.
Researchers at UNC are collaborating with law enforcement agencies to implement and evaluate two new opioid addiction treatment programs for people in the criminal justice system. The initiatives aim to expand access to substance use treatment and reduce overdose deaths nationwide.
Researchers at Mayo Clinic have identified two distinct pathways for lung adenocarcinoma development, which can inform treatment strategies and predict patient response. The study's findings suggest that targeting specific pathways may provide alternative treatment options for patients with limited response to traditional therapies.
A new study questions the statistical evidence underpinning therapies designated as 'Empirically Supported Treatments,' finding that only a small number have strong underlying evidence. The researchers assessed 78 ESTs with low power and replicability estimates, highlighting the need for broad-scale reassessment of psychotherapies.
The American Thoracic Society has published a clinical guideline on the evaluation and management of obesity hypoventilation syndrome (OHS), a breathing disorder affecting obese individuals. The guideline aims to improve early recognition and effective treatment, reducing morbidity and mortality.
A new study has found that elderly cancer patients who are HIV-positive have poorer outcomes compared to those without the virus. The research found higher mortality rates from breast and prostate cancers among HIV-infected patients.
Researchers propose three concepts from complex systems science to study animal social complexity: scales of organization, compression, and emergence. These concepts may help researchers better understand the level of complexity in animal societies across different scales.
Researchers developed an elastic polymer with broad-spectrum antimicrobial properties, effectively killing viruses and drug-resistant bacteria. The polymer's unique molecular architecture attracts water to kill microbes within five minutes, making it a potential solution for hospital-acquired infections.
A national study found that combining early home health nursing with at least one outpatient physician visit after hospital discharge reduces the risk of 30-day hospital readmission for sepsis patients. The intervention facilitates coordinated care planning and early surveillance, resulting in improved outcomes.
Scientists have developed a new computational method that reveals genetic patterns in individual cells, enabling the diagnosis of specific genetic defects and potentially rectifying them with CRISPR. This breakthrough advances precision medicine by providing personalized treatment options for patients with unexplained infertility.
Patients who received lifestyle counseling at least once a month had lower rates of cardiovascular events and death compared to those who did not. The study found a significant decrease in blood glucose levels among patients who received frequent counseling.
Researchers found that turtle embryos can move around to find optimal temperatures, influencing their own sex determination. This behavior may help turtles buffer the effects of climate change by producing a balanced sex ratio.
Researchers have developed amorphous/crystalline heterophase PdCu nanosheets with high chemoselectivity and catalytic activity. The phase transformation behavior of these nanosheets affects their properties, leading to improved catalysis in hydrogenation reactions.
The Argonne-led Center for Electrochemical Energy Science has developed two new electrode technologies that use graphene to improve lithium-ion battery properties. These advancements have led to increased power, lifetime, and safety, as well as the ability to function at low temperatures, critical for electric vehicles in cold regions.
A new study has found that ursodeoxycholic acid, the current recommended treatment for intrahepatic cholestasis of pregnancy, is ineffective in preventing preterm birth and stillbirth. The trial of 605 pregnant women with ICP found no meaningful improvement in outcomes with the drug.
Biomedical researchers have created three-dimensional cell structures from diseased tissue of patients to study endometrial diseases like endometriosis and cancer. This new biobank can help unravel disorders and test drugs for effective treatments.
Researchers found that Edinburgh has the highest rate of inflammatory bowel disease globally, with one in 98 people expected to be affected by 2028. The study highlights the need for more resources to provide patients with research, treatment, and care.
Researchers have developed a blood test that can detect Alzheimer's disease with 94% accuracy when combined with age and genetic risk factor. The test measures levels of amyloid beta in the blood to predict brain changes, potentially allowing for earlier intervention.
The study found that orthopedic, inflammatory, and pain conditions are the main types of medical conditions treated with stem cells at direct-to-consumer stem cell clinics in the Southwest. The researchers also identified differences in the degree to which listed expertise matches the medical conditions treated with stem cells.
The study reveals that hot Jupiter WASP-121b is losing its hydrogen and helium atmosphere due to strong gravity, allowing heavier elements like magnesium and iron to escape. The observations provide insights into the planet's extreme environment and its potential for hosting life.
Researchers analyze EU Commission's Common Agricultural Policy (CAP) reform proposals and find they do not reflect public demand for sustainable agriculture or environmental goals. The CAP has the potential to support multiple UN Sustainable Development Goals but currently only contributes to two of them.
Autopsies reveal that meth users have increased deposits of collagen in the heart muscle, leading to irreversible damage and an enlarged heart. The study suggests that monitoring heart function is crucial for early detection and prevention of further deterioration.
Research from the University of Copenhagen found that remnant particle cholesterol in the blood is constantly increasing and often remains at a high level for life. Maintaining a normal body weight is key to reducing remnant cholesterol and triglycerides, according to experts.
A team of scientists used a microscopic drop of ancient seawater to show that plate tectonics on Earth began 3.3 billion years ago, 600 million years before the previous estimate. This discovery provides insight into the first stages of plate tectonics and the start of stable continental crust.
A recent study from the University of Texas at Austin suggests that a priority rule for organ donors could lead to a decline in the quality of donated organs. The researchers propose a solution of a 'freeze period' to ensure a higher organ supply without compromising quality.
Tropical Storm Wipha is centered off the southeastern coast of China with bands extending over Hainan Island and Guangdong Province. The storm is expected to make landfall in Vietnam's Gulf of Tonkin on August 3, dissipating shortly after.
Research reveals inbreeding depression significantly impacts Helmeted Honeyeater population, with the most inbred birds producing fewer offspring. Gene pool mixing is proposed as a solution to reduce harm caused by inbreeding.
The updated guideline prioritizes early diagnosis, prompt intervention, and reduced unnecessary tests to improve patient outcomes. Enhanced emphasis on patient education and shared decision-making aims to optimize care for patients with sudden sensorineural hearing loss.
A German university-led research project is investigating and testing biological methods for remediating soils contaminated with metal. The goal is to find the best combination of fungi and trees to convert heavy metals into biominerals or remove them from the soil.
A new study suggests that digital games can be an effective way to unwind and recuperate after work. Participants who played shape-fitting games reported feeling more energized and relaxed compared to those using mindfulness apps.
A Rutgers-led study shows that permeable concrete pavement can reduce pavement temperature by up to 30% and reflect more heat than asphalt pavement. The design improves with high thermal conductivity, further reducing heat output.
Researchers recreated barn owl brain circuitry in electronics, mimicking the ability to locate prey using sound to within one to two degrees. The electronic circuit can supersede the owl's precision by orders of magnitude and may lead to more accurate and energy-efficient navigation devices.
A novel RSV vaccine candidate, DS-Cav1, has shown early promise in a Phase 1 clinical trial, prompting large increases in RSV-neutralizing antibodies. The vaccine induced a sevenfold increase in neutralizing antibody levels after a single dose of 50 μg and a 12-fold surge with a dose of 150 μg.
Researchers discovered a new mechanism by which microorganisms protect themselves against highly reactive molecules known as free radicals. By accumulating lysine and altering their metabolism, yeast cells can produce antioxidant glutathione, increasing their resistance to cell damage.
Researchers have identified a contagious form of cancer in dogs, known as CTVT, which has persisted for thousands of years. The study reveals that cancer cells can evolve and stabilize over time, offering new insights into human cancer development and treatment.
A workshop at the University of Texas at Arlington aims to develop a holistic approach to urban watershed management in North Texas. The event will bring together experts from various disciplines to discuss the environmental impacts of infrastructure, climate change, and economic growth on the Trinity River Watershed.