Research finds that older brains have a higher rate of tau protein spread, contributing to Alzheimer's disease progression. The study uses gene vectors to demonstrate this connection in mice, raising questions about therapeutic options and disease mechanisms.
Researchers at Osaka City University develop a quantum algorithm to determine spin quantum numbers on quantum computers, enabling accurate wave function calculations. This breakthrough solves complex issues in chemistry and physics, accelerating the development of practical quantum computers.
Researchers have discovered that pea gin can significantly reduce greenhouse gas emissions, water pollution, and fossil energy consumption. By using peas instead of wheat grain, distilleries can produce carbon-neutral gins with minimal environmental impact.
Researchers found that smaller silver nanowire diameters reduce toxicity to cells, with wires adopting crumpled forms within endolysosomes for containment. This could lead to increased transparency and device performance without compromising safety.
A WVU study found that only folic acid and omega-3 supplements showed promise in reducing cardiovascular risk. Eating less salt was also beneficial for overall survival and cardiovascular mortality rates. However, the quality of evidence supporting other supplements and diets was considered low due to methodological issues.
Researchers developed colorful perovskite solar cells by depositing a uniform perovskite thin layer into arrayed nanobowls acting as a structured electron transport layer. The cells exhibited high-efficiency photovoltaic performance with up to 16.94% efficiency, overcoming previous color limitations.
A 160,000-year-old archaic human molar fossil discovered in China provides morphological evidence of interbreeding between archaic humans and Homo sapiens. The study reveals a rare three-rooted lower molar trait that was previously thought to have evolved after H. sapiens dispersed from Africa.
Researchers from Northwestern University have developed a new predictive model for growth that challenges traditional models of product adoption. The study found that substitutive products exhibit power law growths, which are slower than exponential after an initial flash of excitement.
City of Hope scientists develop blood test to forecast breast cancer recurrence risk in patients with solid tumors. The innovative approach aims to personalize treatment strategies and improve patient outcomes.
A new study from the University of Cambridge found that patients with diabetes who have an empathetic GP are at a lower risk of early death. The study analyzed data from 867 individuals and found that those with better experiences of empathy had a significantly lower risk of death over the subsequent 10 years.
A new study published in Psychiatry Research has concluded that psychiatric diagnoses are scientifically worthless as tools for identifying discrete mental health disorders. The study found significant overlap in symptoms between diagnoses and highlighted the limitations of diagnostic manuals such as the DSM.
Researchers at Purdue University have discovered a novel set of MYC promoter G-quadruplex stabilizers that demonstrate anticancer activity in human cancer cell cultures. The agents downregulate the expression of the MYC oncogene, which is overexpressed in cancer and associated with all aspects of cancer development.
Boston University researchers suggest making buprenorphine available behind the counter with age and quantity limitations to increase access for treating opioid use disorder. This could lead to reduced health costs, lower drug-related crime, and more lives saved.
A large-scale study found elevated levels of a biomarker for uranium toxicity in Kuwaiti children who developed obesity and metabolic syndrome. The study suggests that uranium exposure may contribute to the country's high rates of obesity and diabetes.
A study by Herrera et al. reveals that federal protections in Brazil's Amazon reduce deforestation more effectively than state-level measures. The results suggest that the effectiveness of protected areas depends on the level of government involvement.
A GW pilot study found topical collagen powder to be as effective as primary closure for punch biopsy wound treatment and possibly superior in early cosmetic outcomes. The study showed that wounds treated with collagen healed at least as well as those treated with primary closure.
A team from Kyoto University's Primate Research Institute found that female red skin color acts as a 'badge' of their social status, not fertility. Female Japanese macaques with darker/redder hindquarters are of higher social rank.
Researchers at the University of Tsukuba developed a reusable nanostructured graphene system to efficiently remove water from algae biomass, preserving environmental benefits. This innovation increases the yield of eco-friendly biofuels, pharmaceuticals, and fertilizers.
A new imaging method developed at Cornell University helps remove pollutants from water by identifying optimal catalyst particle sizes and shapes. The technique, called COMPEITS, reveals previously unknown behaviors of catalysts, rendering pollutants nontoxic.
Engineered tobacco plants can produce industrial enzymes and proteins at a third of current cost, with potential to reach $300 billion market. Researchers successfully raised non-native proteins in the field, defying conventional wisdom.
Researchers discovered that people who experience boredom often have more anxiety and depression. To cope, individuals can shift towards left brain activity, engaging themselves in activities like reading or planning meals.
Scientists have identified a marine bacterium that can break down the polysaccharide ulvan from sea lettuce into fermentable monosaccharides. This discovery opens up new possibilities for biotechnological exploitation of ulvan, particularly in the agrifood and cosmetics industries.
A new Portland State University study demonstrates how planting more vegetation, using reflective materials on hard surfaces, and installing green roofs can help cool urban heat islands. The research found that these solutions can make a significant difference in reducing temperatures, even when applied in combination.
A comprehensive study of MS patients found that gadolinium deposition occurs early in the disease, but does not have a clinical impact. However, male patients showed more deposition than female patients, which may be related to dosage based on weight.
A new Y-shaped synthetic consortium achieves 21 g/L butanol yield, exceeding theoretical value by 85%. The consortium's adaptability and stability enable efficient simultaneous utilization of mixed sugar ratios and aeration conditions.
A recent study published in Journal of Climate confirms that the Tibetan Plateau plays a key role in enhancing East Asian summer monsoon circulation under global warming. The study found that enhanced latent heating over the plateau stimulates cyclone anomalies, leading to stronger southerly winds in East Asia.
Scientists analyzed oxygen isotopes in stalactites and stalagmites from 39 caves worldwide to understand past groundwater recharge. The study found that cave drip water oxygen composition varies between cool and warm climates, providing insights into climate variability and water resources.
Researchers at UMass Lowell have discovered that eggshell particles can increase bone cells' ability to grow and harden, potentially resulting in faster healing. The technique uses crushed eggshells in a hydrogel mixture to support bone growth, offering a sustainable alternative to traditional methods.
Researchers discovered that the Venus flytrap's tactile sensors respond to minute pressure stimuli, converting them into electrical signals that cause the trap to close. The plant has evolved smaller traps to detect the smaller forces generated by lightweight mosquitoes.
A USC study tracked prescription opioid and heroin use in teens over time, finding that those who used painkillers to get high were more likely to start using heroin by high school graduation. The study suggests a link between nonmedical opioid use and later heroin use among youth.
A new study reveals that age-related and noise-induced hearing losses affect the brain's sound processing differently. Researchers found that mild noise-induced hearing loss causes similar processing impairment as moderate to severe age-related hearing loss.
Researchers from Columbia University and Harvard are collaborating on a $1 million project to advance ultracold chemistry, enabling the study of previously inaccessible molecular species and reactions. The team aims to create a range of molecules using metal attachment and laser cooling techniques.
Researchers at Tel Aviv University have made a breakthrough discovery in genetic sex selection, allowing for the production of only female offspring in mammals. The study uses a CRISPR-protein approach to guide gene editing, eliminating male embryos while leaving females unaffected.
A new study found that nearly two-thirds of pneumonia patients in Michigan hospitals received excessive antibiotic prescriptions, with most written during the discharge process. This over-treatment can lead to physical side effects and does not improve patient outcomes.
A new international consensus document provides guidelines for the conduct of magnetic resonance imaging studies after a myocardial infarction. The main outcome measure recommended is absolute infarct size, with scanning timing between 3 and 7 days post-infarction.
Researchers developed a novel method to identify patients at high risk of HIV infection, which can benefit from preexposure prophylaxis (PrEP) strategies. The algorithm analyzed electronic health records and successfully distinguished between patients who did or did not acquire HIV, with high precision.
A study by the University of Saskatchewan found that medicinal cannabis oil containing CBD and THC can reduce or end seizures in children with severe, drug-resistant epilepsy. The research team tested a dosage regimen that showed significant improvements in quality of life for the children, with some experiencing complete seizure freedom.
Scientists at the University of Toledo have discovered a new class of cancer-killing agents that target and destroy cancer stem cells. These findings hold promise for developing effective treatments for sarcomas and a subtype of breast cancer known as claudin-low breast cancer.
Scientists have developed a new method to detect signs of early life in ancient rock formations by analyzing high concentrations of potassium. This approach is promising as it could help identify the presence of microorganisms in sedimentary rocks dating back 2.1 billion years.
A study by the University of Adelaide and international researchers has shown that it is possible to breed cattle with reduced methane emissions. The genetics of an individual cow strongly influence the make-up of microorganisms in its rumen, allowing for selection of cows with lower levels of methane-producing bacteria.
Researchers developed a method to predict disease-associated variant (DAV) impacts using evolutionary coupling analysis. This approach identifies DAVs at less-conserved sites that current methods miss, enabling discovery of new biomarkers and therapeutic targets.
A team of international microbiologists warn that ignoring microorganisms in climate change could lead to dire consequences. They advocate for improved literacy about the topic to address the climate disaster and encourage future generations to understand the microbial world.
The DoRIoT project aims to enable statutory regulations and industry standards on data security, reliability, and privacy in the Internet of Things. By developing self-organizing migration of services, companies can operate independently of cloud infrastructure and reduce traffic and reaction time.
A recent study by Chiaki Takahashi at Kanazawa University discovered that the cancer gene RB promotes tumor growth by altering the tumor microenvironment (TME). The TME changes enable the accumulation of immunosuppressive cells, which overpower the body's natural defense system.
A new study published in School Effectiveness and School Improvement found that pre-schoolers whose parents regularly read and talked about books with them scored better on math tests at age 12. The study, led by Dr. Simone Lehrl of the University of Bamberg, assessed 229 German children from age three until secondary school.
A robot developed by the University of Cambridge has successfully harvested iceberg lettuce in various field conditions, demonstrating potential for expanding robotics in agriculture. The 'Vegebot' uses machine learning to identify healthy lettuces and cut them without crushing, reducing physical demands on manual harvesting.
A global analysis of cave drip waters reveals vital clues for understanding past rainfall patterns. In warmer climates, oxygen isotopes in stalagmites display the balance between wet weather events and prolonged drying periods.
A new combination of targeted therapies improved overall survival and objective response in patients with BRAF-mutant colorectal tumours. The BEACON CRC Phase III trial showed that triplet therapy significantly outperformed standard care, suggesting a potential replacement for chemotherapy for eligible patients.
Researchers at La Trobe University have discovered a protein that can sense vital phosphorus levels in plants and adjust growth and flowering accordingly. This breakthrough has the potential to reduce fertiliser wastage and improve crop efficiency, leading to significant environmental and economic benefits for farmers.
A phase III trial found that a three-drug combination of encorafenib, binimetinib, and cetuximab significantly improved overall survival in patients with BRAF-mutated metastatic colorectal cancer. The treatment resulted in a median overall survival of 9 months compared to 5.4 months for standard therapy.
A study at ESMO World Congress on Gastrointestinal Cancer 2019 found that a more flexible dosing regimen for regorafenib improves patients' quality of life while maintaining its efficacy. The reduced and intermittent dose groups showed numerical improvements in tolerance to side effects such as fatigue and hand-foot syndrome.
The NASA-NOAA satellite captured images of four naturally caused fires in Gila National Forest, New Mexico, sparking concern for air quality and fire management. Three fires - Black Fire, South Fire, and Woodrow Fire - generated smoke plumes visible from space.
The Whiting Knoll Fire in east central Arizona has generated enough smoke to be seen from space, with NASA-NOAA satellite images capturing its extent. The fire, which started on June 30, 2019, is burning approximately 1,546 acres and remains only 5% contained.
Researchers observe native ferroelectric metal in bulk crystalline tungsten ditelluride at room temperature. The material exhibits bistable and electrically switchable spontaneous polarization states, enabling potential applications in nano-electronics.
Researchers at MIT have developed a new way to create complex structures in thin films using self-assembling block copolymers. The method produces novel patterns that deviate from regular symmetries, exhibiting interlocking areas with regular patterns similar to quasicrystals.
A study used implicit and explicit bias measures to evaluate how healthcare professionals associate men and women with career and family. The research found that surgeons were more likely to perceive men as better suited for surgery and women for family medicine, leading to potential biases in patient care.
UTA researcher Surendra Shah has been inducted into the Academy of Athens for his work on making concrete production more energy-efficient and environmentally sustainable. His research focuses on nanomaterial applications to improve the use of composite materials and reduce carbon footprint.
Researchers have discovered that Schwann cells can spread myelin across multiple axons, overturning the traditional understanding of these cells' function. This finding could lead to new gene-therapy techniques to repair damaged myelin in peripheral nervous system disorders like Charcot-Marie-Tooth disease.
In the absence of gasdermin D, caspase-1 induces apoptosis, but not pyroptosis, in macrophages. Caspase family members caspase-3 and caspase-9 are involved in this process. The study suggests that caspase-1 activates Bid, a pro-apoptotic protein, which induces cytochrome c release from mitochondria and subsequent apoptosis.
Hurricane Barbara is being torn apart by winds outside its storm, with a weakening trend expected. The storm's eyewall structure is disintegrating, and cooler sea surface temperatures are ahead of the storm.