A study published in JAMA Network Open found a higher risk of cancer among children and young adults with congenital heart disease compared to the general population. The researchers analyzed national registry data from Sweden, assessing cancer incidence from birth to age 41.
Researchers estimated Earth's potential for additional tree cover, which could cut atmospheric CO2 levels by 25%. The study suggests an extra 0.9 billion hectares of tree cover, storing over 200Gt of carbon, equivalent to two-thirds of human-made emissions.
A biochemical oxygen sensor conserved across biological kingdoms allows both plant and animal cells to sense changes in oxygen levels. The newly identified enzymatic oxygen sensor is functionally identical in plants and animals, with potential implications for addressing cellular hypoxia in human diseases like cancer.
A leading public health expert is calling for strategic green burial corridors alongside major transport routes due to Britain's rapidly depleting graveyards. With 500,000 annual deaths in England and Wales, no burial space will be left within five years.
Social prescribing can be an effective means of integrating people into work, but cultural and practical barriers must be addressed. Additional funding and expertise are needed to fill a gap in capacity and provide training for social prescribing practitioners to develop the relevant expertise.
Researchers developed a new technique called VEGAS, which enables rapid development of scientific tools and new treatments for diseases in mammalian cells. The method can yield useful new molecules within days, providing scientists with a powerful research tool.
A study found that a naturally occurring strain of the common cold, coxsackievirus CVA21, can target and destroy bladder cancer cells without causing harm to healthy cells. The treatment showed significant reduction in tumour burden and removal of disease in one patient after just one week.
Researchers at Stanford University School of Medicine have developed a computer algorithm that integrates various predictive data to generate a single, dynamic risk assessment for cancer patients. The algorithm, termed CIRI, outperformed standard methods in predicting patient outcomes and identifying better treatment options.
The team discovered that the belt forms seasonally in response to two key nutrient inputs: human-derived from Amazon River discharge and natural from West African upwelling. The blooms are expected to be a new normal, with data indicating a possible regime shift since 2011.
A new study by the Crowther Lab suggests that global forest restoration could capture two-thirds of human-made carbon emissions. The study found that there is potential to increase the world's forest land by a third without affecting cities or agriculture, with forests capable of storing 205 billion tonnes of carbon once mature.
A new study by ETH Zurich reveals that reforestation efforts could store two-thirds of the 300 billion tonnes of carbon released into the atmosphere since the Industrial Revolution. The greatest potential for forest restoration lies in six countries: Russia, US, Canada, Australia, Brazil, and China.
The Great Atlantic Sargassum Belt experienced a major bloom every year from 2011 to 2018, except for 2013. The study found connections between annual bloom events and nutrient inputs, including human-derived fertilizer use and natural oceanic conditions.
A novel surgical technique connects functioning nerves with injured nerves to restore power in paralyzed muscles, enabling participants to perform everyday tasks independently. The study suggests that nerve transfers can achieve similar functional improvements to traditional tendon transfers, with the benefit of smaller incisions and s...
Scientists at University of Utah Health and Merck Research Laboratories found that altering the production of ceramides can reverse insulin resistance and fatty liver disease in obese mice. By deactivating an enzyme called DES1, they lowered total ceramide levels, improving metabolic health.
A new project at the University of Exeter aims to discover how economics can help protect the environment by placing an economic value on biodiversity. The project will develop trading platforms to advance price measurements of biodiversity and provide individuals and businesses with access to conservation solutions in various countries.
Researchers at TUM and TU Braunschweig have developed a camera-based optical reference system that enables completely automated landings of smaller aircraft without the need for ground-based systems. The system uses GPS signals and custom-tailored image processing software to determine the aircraft's position relative to the runway.
Researchers have created a compact, portable camera that can image polarization in a single shot, revealing the reflected and transmitted light around us. The device uses metasurfaces to direct light based on its polarization, allowing for new applications in atmospheric science, remote sensing, facial recognition and more.
Researchers have identified how precision cancer drugs work, enabling new applications and combination therapies. The discovery reveals the role of PARP proteins in DNA repair, increasing sensitivity to radiation therapy and potential for treating aggressive cancers.
Researchers found over 1,000 entangled shark and ray individuals, with true numbers likely higher due to under-studied cases. Entanglement causes significant animal welfare concerns, despite being considered a lesser threat than commercial fishing.
The study reveals substantial differences between male and female roundworms, with sex-specific behaviors linked to distinct synapse strengths. The findings mark a major milestone in connectomics, the effort to map neural connections, and may provide insights into neurological disorders such as schizophrenia and autism.
Researchers identified a compound that promotes a vigorous immune assault against pancreatic tumors, significantly shrinking them and improving survival. The compound, ADH-503, shifts the balance of myeloid cells toward those that activate T cells to attack cancer, making resistant cancers susceptible to immunotherapy.
A new report by American Cancer Society researchers calculates that cancer took 8.7 million years of life and $94.4 billion in lost earnings among US residents aged 16 to 84 in 2015. Lung cancer was the leading cause of lost earnings, followed by colorectal, breast, and pancreatic cancers.
Erectile dysfunction affects a significant portion of the global population, with estimates ranging from 3% to 76.5%. Early detection and screening may improve quality of life and prevent cardiovascular disease.
A study analyzing cancer deaths in the US found that premature mortality resulted in substantial economic losses, with $94.4 billion estimated lost earnings in 2015. The analysis also highlighted large variations in lost productivity across states.
Researchers have demonstrated a method for getting high-energy photons to kick out two electrons instead of one, potentially breaking the theoretical solar-cell efficiency limit. The new approach could add several percentage points to the maximum output of conventional silicon cells.
Researchers have pinpointed restoration hotspots in 15 countries across four continents, offering the biggest carbon, water, and wildlife benefits. The study identifies over 100 million hectares of lost lowland tropical rain forests that can be restored to overcome rising global temperatures.
The study demonstrated the potential of body-on-a-chip systems to transform the drug discovery process by accurately predicting cardiotoxic mechanisms and replicating in vivo results. The findings support the use of in vitro models to evaluate temporal pharmacokinetic/pharmacodynamic relationships.
SMU's 'Titans in a jar' project aims to recreate Titan's conditions in laboratory cylinders, helping assess the possibility of life on the moon. Researchers will study chemical structures and organic minerals to understand Titan's potential for past or present life.
Researchers find that targeting a specific genetic mutation can alleviate psychosis symptoms by restoring glutamate function and glycine levels. The study provides proof-of-principle for a new approach to treating psychotic disorders using genotype-based treatment.
Researchers analyzed samples from over 1,000 type 1 diabetes patients for 50 years or longer and found a protective protein called RBP3. Injecting RBP3 into rodents blocked diabetic retinopathy without severe side effects.
Researchers used NASA data to predict the corona's appearance during a total solar eclipse, assessing and improving their models. Their prediction featured a nebulous corona with two wide streamers, which they confirmed with post-eclipse observations.
A Stanford University School of Medicine study found that immune cells called killer T cells infiltrate neurogenic niches in the aging brain, secreting a substance that chokes off new nerve cell production. This breakthrough could lead to progress in treating age-related brain deterioration and finding treatments to reverse it.
A new study using satellite data reveals large inequalities in progress towards universal access to electricity in sub-Saharan Africa. The research provides a high-resolution gridded dataset to assess electrification in the region, enabling policymakers to prioritize support for infrastructure expansion and track progress over time.
Researchers analyzed 10,000 perfumes and found that less-common notes and accords are more likely to be successful in online reviews. Generic notes like floral notes and well-represented ingredients like musk or vanilla also play a significant role in perfume success.
Thomas Ebbesen, a renowned physical chemist, has been awarded the prestigious CNRS Gold Medal for his groundbreaking work in nanosciences. His research has enabled technological breakthroughs in optoelectronics and biosensors, and he is recognized for his pioneering discoveries in carbon materials and molecular systems.
A collaboration between amateur astronomers and the Ministry of Defence has successfully used high-end consumer equipment to track satellites in space. The project shows that small aperture prosumer level lenses can monitor positions and maintain accurate orbits for low Earth orbit satellites.
A study in the Journal of Diabetes Investigation reveals that adults with type 2 diabetes are at a higher risk of dying from cancer compared to the general population. The research found that cancer accounted for 27.8% of deaths among those with type 2 diabetes, while heart disease was the leading cause in the general population.
Researchers engineer bacteria to target CD47 on cancer cells, inducing local inflammation and boosting T cell activation. The therapy leads to complete tumor regression and reduced metastasis in mouse models.
Researchers found that two specific biomarkers were elevated in athletes who experienced concussions, indicating potential for longer recovery times. The study suggests these biomarkers could aid in predicting which athletes are more likely to need extended recovery periods after concussion.
A new study published in the European Journal of Neurology found that active sexual life is associated with reduced disability and improved quality of life in men with early Parkinson's disease. The analysis of 355 patients over two years suggests that exploring a patient's sexual life could be beneficial for their treatment.
A home-based exercise program improved anxiety, mood, and social and emotional well-being in older patients with cancer who received chemotherapy. The program, which included low- to moderate-intensity aerobic and resistance exercises, showed positive results for those starting with worse anxiety and mood disturbances.
A study of 17,018 individuals with autoimmune diseases found a twofold increased risk of developing Crohn's disease and ulcerative colitis after treatment with etanercept. This association suggests that anti-TNFα agents may provoke inflammatory bowel disease through common immune dysregulation mechanisms.
Researchers at McGill University discovered how a specific mutant form of the SLC9A6 encoding gene affects neurons' ability to form connections. The study provides clues for new treatments, potentially benefiting patients with Christianson Syndrome and other neurodegenerative disorders.
A study by the University of Exeter found that mycoprotein stimulates post-exercise muscle growth more effectively than milk protein. This breakthrough could have significant implications for those seeking to reduce their meat intake while maintaining optimal muscle mass.
A study reveals a link between depression and severe inflammatory bowel disease (IBD) symptoms, as well as reduced emotional recognition in individuals with IBD. Psychological interventions targeting these biases may be effective in preventing or treating depression in high-risk patients.
University of Birmingham researchers found that the BRCA1 gene changes shape to protect vulnerable DNA until copying machinery can be restarted. This discovery could help understand how cancers develop and potentially identify new ways to suppress tumors.
Experts like Lincoln Taiz conclude that plants don't possess the threshold brain structure for consciousness. They argue that plants' responses to stimuli are genetically encoded and not indicative of intentional choice or learning.
Researchers found signs of activation in resting B cells, which precede the activation of immune cells in people with systemic lupus erythematosus (SLE), a previously underappreciated stage of the disease. The study identified patterns of gene activity that could be used as biomarkers for disease development.
A new study reveals that protein-linked sugars play a critical role in the uptake of alpha-synuclein proteins, which are associated with Parkinson's disease. The research identifies neurexin 1β as a key regulator in this process and suggests potential therapeutic targets for treating the disease.
Researchers found a targeted treatment that reduces psychosis symptoms by targeting a specific structural mutation in the GLDC gene. The study used glycine and D-cycloserine to improve clinical symptoms in participants with four copies of the GLDC gene, suggesting a molecular subtype that may respond to treatment.
Researchers at Columbia University have successfully controlled a visual behavior in mice by activating specific groups of neurons in their visual cortex. The study used high-resolution optogenetics and two-photon calcium imaging to identify and target individual neurons, demonstrating the causal role of neuronal ensembles in behavior.
NASA's GPM core satellite detected the heaviest rainfall rates in Hurricane Barbara, exceeding 50 mm per hour around the eye. The storm is expected to weaken, transitioning from a category 4 hurricane to a tropical storm on Friday.
Researchers have successfully stored and retrieved kilobyte-scale image files using artificial metabolomes, demonstrating a proof-of-concept for wider ranges of molecule-based data storage. The study's findings suggest that small molecules can store more information density than DNA and offer potential for in-solution computations.
Researchers have identified a protein, TSPYL5, that allows cancer cells to survive indefinitely. Targeting this protein may help develop new therapies for children with ALT-type cancer, which currently lacks effective treatments.
A joint Australian-Indian study has identified a new genetic variation associated with schizophrenia, found in over 3000 individuals. The research highlights the importance of studying diverse populations to understand the complex causes of the disease.
Researchers call for better diagnosis and treatment protocols due to misdiagnosis, resource waste, and patient discomfort associated with BMS. The condition's symptoms can be easily treated if underlying causes are identified.
A substantial increase in BMI has been observed since the 1960s, with both genetically predisposed and non-predisposed individuals experiencing weight gain. The study's findings suggest that genetic predisposition interacts with an increasingly obesogenic environment to contribute to higher BMI in recent decades.
Researchers at the University of Bristol have made a world-first discovery by hijacking bacteria's homing ability to guide stem cells to cardiac tissue. The breakthrough could improve treatment for cardiovascular disease, which causes over a quarter of all deaths in the UK.
A type of blood pressure lowering medication called calcium-channel blocker may be linked to an increased risk of a bowel condition called diverticulosis. The study found that genetic variants related to this type of drug were associated with a higher risk of the condition.
Researchers use Word2vec to analyze relationships between words in scientific literature, predicting discoveries of new thermoelectric materials years in advance. The algorithm learns concepts like the periodic table and crystal structure of metals without human guidance.