A smartphone app called PainCoach helps patients reduce their use of opiate painkillers and improve pain control after total knee replacement surgery. The app provides personalized advice on pain relief and exercises to help patients manage their pain levels, resulting in lower opiate use and improved quality of life.
The study's primary endpoint showed that the total neoadjuvant therapy (TNT) approach was safe, associated with high rates of chemotherapy completion (>90%), but did not demonstrate a significant improvement in reducing cancer presence at surgery. Veliparib addition resulted in more side effects and reduced chemoradiation completion, y...
The MONALEESA-7 Phase III trial found that adding ribociclib to hormone therapy significantly improved overall survival in premenopausal patients with advanced HR+ breast cancer, with a 29% lower risk of death. The combination was well-tolerated, with no new side effects emerging.
The NRG-LU001 trial showed that metformin was well-tolerated by patients with locally advanced non-small cell lung cancer, but did not improve progression-free survival or overall survival rates. The study found better-than-expected PFS and OS rates in both treatment arms.
A new study finds that virtual reality hypnosis distraction (VRHD) can reduce anxiety and procedure-related pain during locoregional anaesthesia for orthopaedic procedures. The randomised trial shows a significant reduction in the need for intravenous sedation, with 25% of patients requiring no further sedation.
Scientists have successfully determined the high-resolution three-dimensional structure of proteins inside living eukaryotic cells. This breakthrough technique promises insight into disease-causing proteins and novel drug screening applications.