Researchers developed a probe that accurately traces the sigma-1 receptor on ER surfaces, showing promise for studying neurological disorders and cancer. The probe was tested on prostate cancer cells, haloperidol-sensitive signal detected.
Marco Bottino, a University of Michigan researcher, received the IADR Academy of Osseointegration Innovation in Implant Sciences Award for his work on customized 3D-printed PEEK-AMP dental implants. The award recognizes Bottino's research on bioactive dental implants that enhance osseointegration and improve oral rehabilitation.
Researchers at City University of Hong Kong have been awarded a $100,000 grant to develop a bioreactor that can cultivate multiple strains of probiotic bacteria simultaneously. The goal is to produce low-cost gut microbial biotherapeutics with a target cost of $0.1 per dose.
Patients managing their health via electronic patient portals had fewer emergency room visits and hospitalizations. Access to the portal was associated with more outpatient office visits, fewer emergency department visits, and fewer preventable hospital stays in patients with multiple complex chronic conditions.
Andrea Mombelli, Professor and Chair of the Division of Periodontology at the University of Geneva, has been recognized for his groundbreaking research on periodontal diseases. The 2019 Research in Periodontal Disease Award from IADR acknowledges his contributions to advancing knowledge and improving oral health worldwide.
Research papers examine global cigarette consumption patterns and vaping among adolescents, emphasizing the importance of robust data reporting and effective tobacco control policies. Investments in low- and middle-income countries are crucial to combat industry attempts to delay public health policies.
The study identifies significant knowledge gaps in regional stormwater management and proposes the creation of a centralized database to track maintenance costs, economic benefits, and water quality impacts. A comprehensive approach to green infrastructure is also recommended to consider its effects on community residents.
Dagmar Else Slot, a renowned researcher, has been awarded the 2019 Young Investigator Award by the International Association for Dental Research (IADR) for her groundbreaking work on oral infections and inflammation. She is recognized for her contributions to evidence-based dentistry and prevention of periodontal diseases.
A new roadmap by the Engineering Biology Research Consortium outlines potential breakthroughs in synthetic biology, including genetically modified crops, disease-fighting microbes, and novel biofuels. The report aims to secure federal support for this field to address societal challenges and fuel economic growth.
A study by Vanderbilt University Medical Center found that patients of surgeons with reported unprofessional behavior are more likely to experience complications during or after operations. Surgeons with higher numbers of reports were associated with increased rates of wound infections and other adverse outcomes.
A team of researchers, led by Professor Yu Zhu, has developed a novel shear-thickening electrolyte that can improve the safety of lithium ion batteries used in electric vehicles. The electrolyte becomes thicker under impact, preventing short-circuiting and fires.
Dr. Frank Scannapieco is recognized for his contributions to oral microbiology, with a focus on molecular mechanisms of oral bacterial colonization and saliva-bacterial interactions. He has published nearly 200 research articles and received multiple grants from the National Institutes of Health.
A team of Kyoto University researchers has created the smallest 'Great Wave' ever produced, just 1mm in width, without using pigments. This breakthrough uses Organized Microfibrillation (OM) technology to create a new palette of colors and applications in fields like anti-forgery technology, health, and food safety.
Peter V. Cooney, a renowned dentist and researcher, has been awarded the 2019 International Association for Dental Research (IADR) Honorary Membership for his significant contributions to dental research and improving oral health globally. His impressive career includes leading national dental health surveys and collaborating on public...
Researchers developed a new type of refrigeration using a nanosponge, a soft material with tiny pores, to replace hydrofluorocarbons. The team successfully carried out a force-driven liquid-to-gas phase transition, paving the way for more efficient and environmentally friendly refrigerants.
Researchers found that hydrology plays a greater role in methane emissions than plant species, highlighting the importance of wetland design. Constructed wetlands can be managed to reduce methane emissions by creating favorable conditions for oxygen delivery and soil saturation.
Janet Moradian-Oldak, a researcher at the University of Southern California, has been awarded the 2019 Basic Research in Biological Mineralization Award. Her work on enamel biomineralization and biomimetic approaches has advanced our understanding of tooth development.
High-resolution maps show progress in defeating malaria, but also highlight areas of stagnation and increased burden, particularly in Venezuela and sub-Saharan Africa. The research emphasizes the need for targeted interventions and sustained funding to overcome obstacles to eradication.
A new study found that perceived effectiveness of positive reinforcement and owner confidence are crucial factors in using such techniques. The researchers suggest that practical support and emotional well-being management are essential for owners to develop confidence in training their dogs.
A study by Columbia University researchers found that limiting ovarian cancer surgery to high-volume hospitals could improve survival but also reduce access for many rural and underserved patients. In fact, nearly 35% of low-volume hospitals had better-than-expected outcomes at 60 days and 51% at 2 years.
A recent study found that kindergarteners with attention problems tend to earn less as adults. Additionally, kindergarten ratings of aggression and opposition were also associated with lower earnings only for boys in the study.
Researchers at the University of Maryland have captured evidence of Klein tunneling in a superconductor-superfluid junction, allowing particles to tunnel through barriers. This phenomenon enables engineers to design more uniform components for future quantum computers and devices.
The study found that countries with a variety of crops experience less severe food shortages, with declines in total yield exceeding 25% less common. Researchers encourage nations to evaluate their crop diversity and consider strategies like new drought-tolerant varieties and intercropping to enhance food supply stability.
A study of married couples in Vietnam found that a present-biased spouse tends to receive more money from their spouse's earnings and is less likely to save. External savings commitment devices like retirement plans or ROSCAs can help protect money from a present-biased spouse.
Peter Lockhart, a renowned researcher, received the 2019 IADR Distinguished Scientist Award in Pharmacology for his groundbreaking work on oral medicine and its association with medically complex patients. His research focuses on the dental management of these patients, exploring the links between oral disease and infective endocarditis.
Scientists have identified a rare genetic mutation causing a fatal respiratory disorder that affects newborns. Using CRISPR/Cas9 gene editing technology, researchers developed a mouse model of the disease and discovered a critical link between FOXF1 mutations and STAT3 deficiency.
Researchers at Huntsman Cancer Institute discovered a new experimental drug, selinexor, which may block a crucial survival pathway exploited by myelofibrosis cells. A clinical trial has been designed to examine the drug's effectiveness in patients with myelofibrosis.
A new study finds that groundwater pumping has contributed significantly to US stream flow declines, affecting regions like the Colorado and Mississippi River basins. The research suggests that sustainable water management is crucial to mitigate these impacts and ensure long-term water security.
A $24.8 million grant-funded longitudinal study will examine the long-term impact of vaping, environmental factors, and lifestyle on lung health in millennials. The study aims to identify risk factors, biomarkers, and early interventions for chronic lung diseases.
Researchers at Berkeley Lab's Advanced Light Source employ X-ray Laue microdiffraction to study tiny samples of promising candidate minerals. The technique successfully identifies ognitite, a newly discovered mineral with unique chemical properties.
A meta-analysis of 21 clinical trials involving 83,000 patients found no association between vitamin D supplementation and reduced risk of cardiovascular disease events such as heart attack or stroke. The study's results were consistent across different doses and genders.
The Ecological Society of America's 104th Annual Meeting emphasized the importance of inclusive approaches in ecology, fostering connections between disparate landscapes and disciplines. Key sessions explored the intersection of human and non-human nature, agricultural practices, and environmental justice issues.
Researchers have developed a new strain of microorganisms that can efficiently produce fatty acids and biodiesels from glucose. The resulting strains produced the highest concentrations ever reported by microbial fermentations, making them a potential game-changer for sustainable energy production.
A Vanderbilt team designed a device that captures the natural stumble response of people with two legs, a challenge for those with prosthetic legs. By tripping test subjects 190 times, they aimed to program computer-controlled prosthetics to prevent more falls.
Researchers discovered melanin-concentrating hormone (MCH) neurons in the hypothalamus play a critical role in modulating REM sleep based on room temperature. Mice with functioning MCH neurons increase REM sleep when warmed, while those lacking the receptor show no such response.
The research team developed a system that allows for the real-time observation of MOF adsorption behavior, enabling accurate measurements and assessments of gas adsorption isotherms. By analyzing individual pore molecules, they identified a stepwise adsorption process and quantified the effects of pore structure and adsorption molecule...
Researchers create flexible optical plastic with nano-Enoki mushroom structures that repel liquids while maintaining transparency. The surface resists staining from various liquids, including blood, coffee, and olive oil.
Anibal Diogenes, a University of Texas Health Science Center at San Antonio researcher, received the 2019 IADR Distinguished Scientist Award for his contributions to pulp biology and regeneration. His work has demonstrated novel applications of mesenchymal stem cells in regenerative endodontic procedures.
Researchers studied ocean's carbon cycle to improve climate models and predict future changes. They found the ocean absorbs CO2 slower in the 1990s but faster in the 2000s, influencing atmospheric accumulation rates.
Francesca Bonino, a Tufts University Assistant Professor, received the 2019 AADR William B. Clark Fellowship for her clinical research on dental implants and peri-implant soft tissue properties. The fellowship supports investigators carrying out periodontology research.
Anibal Diogenes received the 2019 IADR Distinguished Scientist Award in Pulp Biology and Regeneration. He was recognized for his contributions to pulp biology and regeneration.
S. Jeffrey Dixon, a Professor at Western University, received the 2019 IADR Distinguished Service Award for his outstanding contributions to the CADR and IADR. He has published numerous papers on mineralized tissue research and served as an editorial board member.
Pumping groundwater for irrigation has decreased streamflow and plant water availability in the US. Groundwater declines have led to a more than 50% decline in some streams, with evapotranspiration also declining in response.
A new scaffold derived from a pig's meniscus has shown promise in repairing torn meniscus tissue. In lab tests, repairs aided by the scaffold resulted in stronger meniscus repairs after four weeks compared to natural healing.
Research from Rice University suggests that white people's expressions of racial apathy can decrease over time, with a shift towards greater care for racial equality. The study also found a correlation between education and lower levels of racial apathy among whites.
An international team of astronomers has captured the first-ever polarized radio waves from a distant cosmic explosion, known as gamma-ray burst GRB 190114C. The discovery provides new insights into how jets are formed in gamma-ray bursts and could shed light on the role of magnetic fields in powering these energetic events.
A new study suggests that elevated estrogen levels in early pregnancy can lead to placenta abnormalities, but treating pregnant women with the growth factor VEGF could halt preeclampsia and preterm birth. Researchers found that VEGF treatment increased uterine artery remodeling and improved blood flow to the placenta.
Researchers have documented surprising amounts of coral living in areas with less than 1% of the surface light, shedding light on deep-sea life and strategies for survival. The study found different corals use varying strategies to deal with low light levels, including changing pigments or symbionts.
A human-on-a-chip model developed by Hesperos, Inc. realistically replicates the responses of cancer treatments, enabling more accurate and efficient preclinical testing. The model demonstrated efficacy and toxicity of anticancer drugs on various cell lines, informing treatment decisions for individual patients.
A newly identified genus and species of freshwater clam, Lithoredo abatanica, was found to eat rocks and expel sand as it burrows in the Abatan River. The shipworm's unique anatomy has revealed new information about its ecosystem engineering capabilities.
Researchers identified a key molecule, mir-135b-5p, found elevated in the brain's emotional memory processor that drives PTSD symptoms. Suppressing this molecule enables faster recovery from trauma, and it may also serve as a novel biomarker for treatment.
A new study reveals Himalayan glaciers have doubled their annual melt rate since 2000, with temperatures averaging 1 degree Centigrade higher than in previous decades. The accelerated melting threatens water supplies for 800 million people and may lead to deadly outburst floods.
The study found that Early Celts in Burgundy imported Mediterranean pottery, olive oil, and wine, and adapted them to their own culture. They used foreign vessels to drink local beers spiced with pine resins, as well as home-grown beverages like millet-based beer.
A new multi-organ-on-a-chip system accurately captures chemotherapies' toxic effects on liver and other organs. The technology enables flexible testing of different organ systems, potentially leading to more accurate drug development and personalized therapies.
A new study identifies 65 genetic variants in understudied minority populations, which could improve precision medicine for these groups. The findings highlight the need for equitable inclusion of diverse populations in genetic research to address chronic disease disparities.
A new platform has been developed that provides suppliers with a certain amount of choice, improving supply and demand matching for underutilized resources. The approach was found to perform better than existing methods, especially when there is limited information about the supplier's preferences.
A new study by Hirosi Ooguri and Daniel Harlow finds that symmetry is not possible in quantum gravity when combined with the holographic principle. This breaks the long-held expectation of physicists and has several important consequences, including proton stability and magnetic monopole existence.
Margaret R. Byers, a University of Washington researcher, received the 2019 AADR Honorary Membership for her significant contributions to dental research. Her work focuses on neurobiology, sensory functions, and immune capabilities of tooth pulp cells.
A new study published in Pediatrics shows that a state-wide quality improvement initiative improved hospital-based breastfeeding support practices and first milk expression among mothers of very low birth weight infants. However, disparities in mother's milk provision persisted after three weeks of hospitalization.
A clinical trial for a new sickle cell disease treatment, IMR-687, has shown early promise with an increase in F-cells and a reduction in pain, improving biomarkers of the disease.