This observational study examines changes in patient volume and treatment for acute heart attacks during the COVID-19 pandemic. The results show that there were significant increases and decreases in case rates, treatment approaches, and patient outcomes before and after the pandemic onset.
Tyrus Berry is developing a semiparametric modeling framework to leverage strengths of parametric and nonparametric methods. The project aims to provide flexible models with quantifiable uncertainty for optimal predictions in limited noisy observations.
A new DNA test can accurately identify individuals whose gonorrhea is curable with a single dose of oral ciprofloxacin, providing an alternative treatment option. The study found that all 106 subjects identified as having the wild-type gyrA serine strain were cured with the antibiotic.
Scientists at UC Berkeley and RUB develop technique to read complex metal arrangement in MOFs using atom probe tomography, enabling encoding of multiple chemical functions. This breakthrough could lead to programmable substances and revolutionize material synthesis.
D. Sarah Stamps will investigate volcano-tectonic interactions during early phase continental rifting at the Natron Rift in Tanzania using GPS and geochemical data. She aims to fill knowledge gaps and advance understanding of volcanic eruptive processes and early phase continental rifting.
Researchers have developed a new CRISPR technique that allows them to target and reduce specific messenger RNA (mRNA) molecules involved in early embryonic development. This approach enables the study of genes that were previously difficult or impossible to manipulate, and has shown promise for understanding infertility and development...
Researchers synthesized current evidence on gene regulatory networks and neuronal networks to understand animal behavior. The integration of these networks reveals complex dynamics, including environmental factors and social behavior influencing gene expression changes.
The Florida Current, a key component of the Gulf Stream, has slowed significantly over the past century, with its strength being the weakest in the past 110 years. This decline is linked to the broader Atlantic Meridional Overturning Circulation (AMOC) system, which plays a crucial role in regulating global climate.
A survey study of US physicians found differences in burnout, symptoms of depression, and career satisfaction based on race/ethnicity. The findings suggest that physicians from diverse racial and ethnic backgrounds experience varying levels of emotional exhaustion and depressive symptoms.
A new treatment option shows promise in improving survival rates for babies with a rare cerebrovascular disorder. The study found that endovascular treatment can reduce the severity of pulmonary hypertension, allowing babies to cross the critical line on their way to survival.
A new study reveals that heavier smokers face a 17-fold increase in emphysema and an 8-fold increase in atherosclerosis. The study found associations with 28 separate health conditions, including lung cancer and cardiovascular diseases.
The study found that implementing antiretroviral therapy (ART) for HIV and newer tuberculosis medications decreases the risk of death for adults with drug-resistant TB. Access to these life-saving medications varies widely globally.
A new combined approach improves prediction of type 1 diabetes in high-risk children, allowing better risk counselling and early intervention. The test doubles the efficiency of newborn screening programmes to prevent life-threatening ketoacidosis.
Researchers successfully promoted plant growth and increased seed yield by expressing high-speed-type myosin XI from Arabidopsis in Camelina sativa, a promising plant for biodiesel. This technology is expected to increase productivity per area unit and has potential applications in other plant species.
Researchers developed a novel CO2 separation technology using gate-type adsorbents, achieving high CO2 selectivity and recovery capacity. The adsorbent's flexible structure generates cold heat during adsorption, suppressing temperature rise and improving system efficiency.
A titanate nanowire mask can trap and destroy pathogens using photocatalytic properties of titanium dioxide, potentially reducing waste and environmental impact of disposable masks
A new experiment has characterised the properties of electrons emitted when adenine, a key DNA nucleobase, is bombarded with high-velocity ions. The study's findings could improve understanding of how radiation damage increases cancer risk in cells.
A newly identified mutation in microsomal triglyceride transfer protein (MTP) may enable the development of more specific inhibitors to reduce triglyceride levels without intestinal side effects. This discovery has important public health implications for cardiovascular disease prevention.
A research team led by Thomas LaToza aims to create a community infrastructure for conducting online software engineering user studies. The proposed platform will increase the quality of software engineering tools and techniques, enhancing productivity and effectiveness among software engineers.
A team of researchers offers new explanations for how living systems form ordered patterns through instabilities in un-patterned systems. The study revisits Turing's theory to prove mathematically how instabilities can occur through simple reactions and widely varied environmental conditions.
Researchers tracked the evolution of stellar eggs in Taurus, discovering internal structures and bipolar gas streams that indicate a star's birth. The team used ALMA's compact array to observe starless cores and found evidence for 'first hydrostatic cores,' short-lived objects formed before a baby star's birth.
A new study by scientists at the University of Cambridge's Autism Research Centre found that transgender and gender-diverse adults are three to six times more likely to be diagnosed as autistic. The research used data from over 600,000 adult individuals and confirmed previous smaller scale studies.
Researchers at The Wistar Institute identified a cell-surface glycomic signature associated with persistent HIV transcription in T cells. This signature, characterized by the presence of fucose and Sialyl-LewisX, may help target hidden HIV reservoirs during antiretroviral therapy.
Chinese scientists introduce FlowRACS, a flow-mode Raman-activated cell sorter, to support high-throughput discovery of enzymes and their cell factories at the precision of just one microbial cell. The instrument can screen yeast for its TAG content and profile in real-time.
Researchers reanalyzed image data from Voyager 1, 2 and Galileo spacecraft to investigate orientation and distribution of ancient tectonic troughs on Ganymede. A computer simulation suggests that the giant crater could have resulted from an asteroid impact with a radius of 150km.
Researchers at Goethe University have isolated an ancient enzyme that enables early bacteria to produce energy without oxygen. The Rnf enzyme functions like a pumped-storage power plant, generating electricity and producing ATP.
Scientists have created a new 3D cell culture model of the pulmonary arterial wall to study pulmonary arterial hypertension. The model successfully recapitulates the process central to the pathogenesis and progression of PAH, allowing researchers to test potential drug candidates for treatment.
A new process developed by SFU chemist Robert Britton and his team allows for the creation of new nucleoside analogues in a fraction of the time previously required. This breakthrough has significant implications for treating viral infections and cancer.
The Smart Rolling Stock Maintenance project aims to reduce costs, increase reliability, and enhance safety through the use of industrial automation and advanced condition monitoring. The project will explore the potential of data analytics to plan and schedule maintenance more efficiently.
The employment-to-population ratio for working-age people with disabilities decreased from 28.4% in June 2020 to 28.1% in July 2020, while the labor force participation rate for these individuals also declined. These findings suggest prolonged unemployment may discourage workers and lead to long-term employment stress.
A new study by USC researchers found that El Niño cycles are an unreliable predictor of droughts in the American West. Instead, Earth's dynamic atmosphere plays a significant role in wet and dry cycles, making drought forecasting challenging.
Researchers at Yale University found that patients with COVID-19 had abnormal liver tests at much higher rates than previous studies, associated with poorer outcomes. The study also discovered a relationship between drugs used to treat severe COVID-19 and liver damage.
Researchers at LMU München report a hydrothermal mechanism that could have promoted the prebiotic evolution of self-replicating molecules. In an experiment, warm water circulation through pores stimulates RNA strand replication, overcoming the initial problem of double-stranded RNA formation.
A study published in Immunity identified five humoral immune response markers that can correctly classify convalescent COVID-19 patients and those who did not survive the disease. These markers, including IgM and IgA1 responses to S protein and N protein, were able to predict patient outcomes more accurately than demographic factors.
Jennifer Lerch received funding from the State of Delaware to provide assistance to the Delaware Department of Corrections in using the Risk-Need-Responsivity (RNR) Simulation Tool. The project aims to enhance the tool's capabilities and address inmate needs.
The study aims to characterize the occurrence and concentrations of pharmaceuticals and personal care products (PPCPs) in water and sediments. The researchers seek to establish a baseline for future evaluations of wastewater treatment technology and public health.
A new scientific statement from the American Heart Association recommends incorporating dietary screening into routine health care visits. The goal is to assess an individual's total dietary pattern and provide actionable next steps, helping patients set achievable dietary goals.
Researchers created a new reporter mouse strain to visualize and manipulate P2X2-expressing cells, revealing their expression in specific subsets of sensory nerves. The study sheds light on the selective targeting of therapeutic approaches to address sensory nerve dysfunction.
Researchers at Kumamoto University discovered that NSD2 enzyme prevents cellular senescence by maintaining cell growth and serum response. Reduced NSD2 leads to increased expression of genes related to cell aging and decreased activity of growth-promoting genes.
Researchers have identified a single gene, SLC20A1, that controls the development of excretory organs and genitalia. Mutations in this gene can cause severe developmental disorders, including bladder exstrophy epispadias complex.
A new study suggests that incorporating climate policies into economic recovery plans can significantly reduce global warming. By investing in green industries, countries can lower traffic pollution and improve air quality, leading to immediate health benefits and a cooling effect on the climate.
Researchers are developing and testing technology for delivering vaccine doses via the skin using microneedles. This innovative approach aims to improve patient compliance and yield better health outcomes, with potential benefits including reduced burden on healthcare systems and increased accessibility for self-administration at home.
Researchers at LMU Munich found activated immune cells and blood platelets play a major role in COVID-19 pathologies, leading to lung failure and systemic clot formation. The study identified a link between virus-induced changes in the lungs and increased thrombotic risk.
Researchers developed a genetically engineered mouse to visualize fluctuations in circadian clocks of cell types. They found that removing clock genes from AVP neurons disrupted the entire SCN network, while VIP neurons were less affected.
Scientists have discovered helium structures in the Sun's atmosphere using a NASA sounding rocket, revealing new insights into the origin and acceleration of the solar wind. The findings suggest that the abundance of helium is strongly connected to the magnetic field and speed of the solar wind in the corona.
A new study from the University of Oregon suggests that parents' views on self-regulation can shape their children's food preferences. By understanding their own sense of self-control, parents can make healthier choices and influence their kids' developing eating habits.
Researchers at the University of Arkansas have developed the first electrically injected laser using semiconducting material germanium tin. The diode laser offers improved micro-processing speed and efficiency at significantly lower costs.
Legume plants use LysM receptor proteins to recognize symbiotic and pathogenic microbes, triggering antimicrobial defense or symbiosis. Researchers identified key residues that separate immune from symbiotic receptors, enabling reprogramming of LysM receptors.
Researchers used probability analysis to estimate the COVID-19 incubation period, finding a median of 7.75 days with up to 14.28 days in some cases. The new estimate improves on previous small-scale studies and could inform containment strategies like quarantines.
A decline in public plant breeding programs is threatening food security in the US, with a 21.4% reduction in full-time employee time over five years. The programs' focus on disease tolerance, production, and drought resistance will be lost if funding does not increase.
A new study from Stanford University's Immigration Policy Lab found that many refugees in the US move to different states soon after arrival, primarily seeking better job markets and social networks. Refugees are more likely to leave high-unemployment states and join those with booming economies.
A modified BACTRAC protocol allows researchers to study local leukocyte populations during human stroke using flow cytometry. This approach provides a better understanding of acute inflammatory mechanisms and may identify immunotherapeutic targets for stroke treatment.
Researchers developed a nanomedicine-based strategy for chemo-immunotherapy that eradicated PTEN-negative glioblastoma cells. The combination of epirubicin-encapsulating nano-micelles and immune checkpoint inhibitors increased tumor-infiltrating T cells and reduced immunosuppressive cells, effectively killing cancer cells.
A new study warns of the potential harm of deep-seabed mining on seabed ecosystems, highlighting a need for better understanding of their sensitivity and biodiversity. The researchers emphasize that many deep-sea ecosystems will be highly sensitive to seafloor mining and are likely to be impacted over larger scales than predicted.
A supersensitive dopamine detector developed using 2D materials can help diagnose disorders such as Parkinson's disease and schizophrenia. The detector is low-cost, flexible, and can detect dopamine in real-time, making it a promising tool for non-invasive monitoring.
A new study by University of Iowa researchers identifies a connection between the East Asian Subtropical Jet Stream and the frequency of tropical storms in the Atlantic Ocean. The study found that stronger EASJ is associated with fewer Atlantic tropical cyclones, suggesting a link between climate systems in Asia and hurricane formation.
The study found that nutrient-poor water is pooled in the intermediate layer, allowing for vertical mixing and transport of nutrients to the surface. This process helps maintain high biological productivity in the subarctic Pacific region.
Scientists have discovered a correlation between high blood lead levels in children and increased methylation of DNA, which affects gene expression. This finding reveals a previously unknown mechanism for lead poisoning and its devastating effects on children's health.
A new study uses patient-specific tumor organoids to identify the most effective chemotherapy protocol for treating advanced stages of colon and appendiceal cancer. The approach shows promise in tailoring treatment to individual patients, potentially increasing life expectancy.
A new study found that glaciers in New Zealand's Southern Alps have lost more ice mass than remains today, with a doubling of ice loss since the Little Ice Age peak extent. The rate of ice loss has accelerated over the past four decades, posing significant impacts on local communities and global sea-level rise.