Researchers have successfully solved the structure of Parkinson's disease-related protein LRRK2 inside cells using a pioneering technique. The study reveals that pathogenic LRRK2 forms exquisitely-organized double-helices around microtubules, suggesting a potential target for therapies.
A recent study published in PNAS found that fires have a significant impact on plant survival and distribution, often exceeding the effects of climate change. The research highlights the importance of considering other environmental factors, such as human land use practices, in understanding biodiversity.
A new study found that only 40% of psychological assessment tools used in courts are favorably rated by experts. Lawyers rarely challenge these conclusions, and when they do, only one-third succeed. The study examined over 360 tools and 372 legal cases across the US.
Researchers developed SABER, a method to multiplex imaging of specific molecules, allowing visualization of rare and low-abundance molecules. The technique enables detection of multiple proteins, DNAs, or RNAs in a single tissue sample, advancing basic biology, biomarker discovery, and clinical diagnostics.
Future factories will require new skills and organizational structures that prioritize human collaboration with robots. Research explores the psychological effects of working alongside large industrial robots and developing tools to enhance robot design.
Researchers have engineered immune cells to target solid tumors using a new cancer immunotherapies approach. They found that T cells can be reprogrammed to turn on tumor cells when exposed to high concentrations of transforming growth factor beta, a protein that suppresses the activity of T cells in the tumor environment.
Researchers discover how Ebola virus interacts with human lipids and how disrupting this interaction can inhibit infection in cell culture. Two FDA-approved drugs show promise in blocking virus replication and spread.
Researchers discovered that dormancy is a natural response to over-predation, allowing zooplankton to survive during food scarcity. Laying dormant eggs can aid population recovery, while regular eggs may not.
Dr. Catherine Nakalembe from NASA Harvest is helping countries in Eastern Africa build systems to monitor crops using free satellite data, enabling life-saving decisions on food security. Combining satellite and ground data with weather forecasts allows for early warnings of crop failure due to drought, floods, disease, or pests.
Researchers developed a new high-throughput technique to study gene splicing, tracking thousands of genes in real-time. The results show that splicing occurs far more often than previously thought, with significant variability in gene expression timing.
Denmark-based researchers have made glasslike Plexiglas stronger, lighter and more flexible by adding specially designed cuts. This technique can improve microchips' durability without increasing material usage.
Research by Arizona State University's Tess Neal found that psychological tests used in courts are not always scientifically valid and are rarely challenged. The study examined 364 commonly used psychological assessment tools and found that only about 40% have generally favorable reviews of their psychometric properties.
Fruit fly sleep is driven by oxidative stress, an imbalance of free radicals and antioxidants. This discovery may explain why chronic lack of sleep shortens life expectancy. By sleeping, cells may mitigate damage from accumulated oxidative stress.
Scientists have resolved the structure of an essential protein for insect smell, suggesting that millions of odor receptors evolved to suit different lifestyles and habitats. The protein Orco forms a common channel with many odor receptors, allowing for diverse adaptations.
Researchers create molecular 'fishing' technology using customized receptors to detect specific proteins in blood, offering a precise diagnostic tool for diseases and drug discovery applications.
A recent study highlights journalism's role in preventing the spread of misinformation, particularly in science and health. According to Dan Gillmor, co-founder of the News Co/Lab, journalists have a special duty to avoid being fooled and help consumers learn to sort out truth from falsehood.
Researchers are exploring enzymes' essential features to convert abundant raw materials into usable fuel. PNNL scientists designed an artificial enzyme that converts carbon dioxide to formate, a potential kind of fuel.
Researchers developed a hydrogel that changes color with radiation exposure, allowing for painless dose monitoring on the skin. The gel is relatively inexpensive and can be used directly on the skin without complex handling.
A new microscopy technique allows researchers to follow individual proteins over long periods of time as they move along and inside live cells. The technique, called interferometric scattering (iSCAT) microscopy, can track proteins with microsecond speeds for extended periods.