A new ECL-based mechanism has been identified that enables quicker, more cost-effective and reliable serological tests. The technique enhances signal detection, allowing for increased sensitivity levels up to 128% compared to current methods.
A team of UTHSC researchers will study genetic differences in stress response, oxycodone consumption and stress-induced drug seeking in rats. The findings have great potential to translate to human conditions of opioid addiction.
Researchers from UTEP have successfully utilized carbon quantum dots to combat neurological disorders, demonstrating their potential in preventing and treating neurodegenerative diseases. The study provides a roadmap for safe use of CQDs in biomedical applications.
A University of Toronto team has been awarded a $1.5 million grant to study the impact of cannabis use on Indigenous oral health in Canada. The study will gather first evidence of the effects of cannabis on Indigenous populations, working in partnership with communities and public health authorities.
Researchers found that GPT1 targets both plastids and the endoplasmic reticulum, enabling simultaneous formation of reduction power. The oxidative pentose-phosphate pathway also occurs in peroxisomes, producing NADPH and ribulose-5-phosphate.
A recent analysis found that kidney transplant patients are at a higher risk of death from COVID-19, with advanced age being the most significant factor. The study, conducted on ERACODA database, showed that 21% of kidney transplant recipients died within 28 days, compared to 25% of dialysis patients.
The COMPASS experiment at CERN is analyzing the proton's inner structure using particle collisions and complex algorithms. The team confirmed a theoretically expected sign change in the Sivers function, which relates to quark orbital motion inside the proton.
A study published in the journal Aging, Neuropsychology, and Cognition found that children who attend school for longer periods have better memory abilities in old age, particularly for women. More years of early-life education counteract age-related memory losses, suggesting a protective effect against Alzheimer's disease.
Researchers developed an advanced quantum algorithm for measuring physical quantities using simple optical tools, exceeding the shot noise limit and achieving Heisenberg-limited sensitivity. This breakthrough enables affordable and effective platforms for moderate-scale quantum measurements and computations.
A new study reveals that almost 13,000 tonnes of microfibres are released into European marine environments every year. Changing laundry habits, such as using cooler wash cycles, could save up to 3,813 tonnes of microfibres being released into marine ecosystems in Europe.
A new report published in the New England Journal of Medicine examines the limitations of COVID-19 diagnostic tests, highlighting concerns over false-negative results. The study emphasizes the need for highly sensitive and validated tests to accurately declare individuals uninfected, ensuring safe reopening of communities.
Scientists have discovered a new killing mechanism in teixobactin, a potent natural antibiotic that can kill superbugs. The research provides fundamental insights into how teixobactins work and could lead to the development of new drugs.
A new study confirms lockdown restrictions reduced COVID-19 transmission in France, but a second wave is possible due to low herd immunity. The R-number, a key measure of disease transmission, fell from 3.2 to 0.47, highlighting the effectiveness of containment efforts.
Researchers identified 27 protein biomarkers in COVID-19 patients' blood plasma linked to disease severity. These molecular signatures can precisely classify patients according to World Health Organization's coding criteria, enabling early diagnosis and treatment.
Heidelberg researchers demonstrate that restoring VEGFD levels can preserve dendritic arborisation and reduce brain damage after a stroke. A treatment using recombinant VEGFD and nose drops achieved similar results in mouse models.
Researchers at Johns Hopkins Medicine found that psilocybin reduces neural activity in the claustrum by 15% to 30%, associated with stronger subjective effects. The study also showed changes in how the claustrum communicates with other brain regions involved in hearing, attention, and memory.
The study mapped bacterial resistance to last-line antibiotics in the Philippines, enabling better tracking of resistant bacteria and controlling outbreaks. The genomic capacity has enhanced national infection control efforts and improved understanding of antimicrobial resistance at local, national, and international scales.
Researchers propose a new model for managing facial recognition technologies at the federal level, citing risks of breach of privacy, surveillance, and profiling. A proposed FDA-inspired agency would categorize these technologies by degrees of risk and institute corresponding controls.
Patients with high disease activity in rheumatoid arthritis are at a higher risk of developing venous thromboembolism. Treatment with biologic disease-modifying antirheumatic drugs (bDMARDs) such as TNF inhibitors can reduce this risk by nearly half compared to conventional synthetic drugs.
NASA's Aqua satellite gathered infrared imagery and cloud top temperature data on Tropical Depression Cristobal, revealing areas of powerful thunderstorms with potential for heavy rainfall. The storm is expected to strengthen later today and regain tropical storm strength in the next 48 hours.
Researchers analyzed DNA from 25 Stone Age individuals and found that those buried in typical Pitted Ware culture graves were genetically similar to earlier Scandinavian hunter-gatherers. The presence of Battle Axe culture influences in some graves suggested trade and cultural exchange between the groups, rather than genetic migration.
Researchers have identified 31 populations of herbicide-resistant annual bluegrass in Australia, highlighting the narrowing options for effective control. The weed has developed resistance to multiple herbicides, including propyzamide and rimsulfuron, with levels of resistance ranging from two-fold to 56-fold.
Scientists at the University of Warwick created a method called MeniFluidics to control cellular patterns, enabling the creation of arbitrary patterns and opening doors for tissue engineering and bio-art. This breakthrough could lead to innovations in antibiotic resistance and biofouling prevention.
Magnetic ionic liquids (MIL) Emim[FeCl4] and Bmim[FeCl4] were examined at room temperature, revealing paramagnetic to antiferromagnetic behavior. A hybrid reverse Monte Carlo method combined X-ray scattering measurements with molecular simulation to reveal precise coordination structures.
Researchers from OIST discovered that curvature at material edges affects wrinkling, with larger windows reducing wrinkles and strain. A theoretical model was developed to explain findings, which could aid in designing devices with functional wrinkles or reduced wrinkling.
Palaeontologists from St Petersburg University have created the most detailed virtual 3D-model of the endocranial cast and blood vessels of the head of an ankylosaurian. They found that ankylosaurs had a unique cooling system, an extremely developed sense of smell, and could hear low-frequency sounds.
MUSC has established two new centers to support digestive and liver disease research, providing stable funding to over 30 investigators and creating a pipeline for future researchers. The centers aim to foster multidisciplinary collaborations and provide necessary resources for cutting-edge research.
Aarthi Narayanan is studying Brilacidin's direct virus-killing activity and its potential as a second dose to infected cells. The researchers aim to determine the optimal timing of treatment using this investigational antibiotic.
A new discovery enables researchers to directly visualize unlabeled nanoscale objects with deep sub-wavelength separations, advancing the field of optical microscopy. This breakthrough has significant implications for applications in semiconductor wafer inspection, nanoparticle sensing, material characterization, and biosensing.
George Mason University's Mark D. Uhen has received funding to create a Paleobiology Database with machine learning tools for automating data entry, reducing expert time and cost. The project aims to improve the usability of the database through user workshops and online resources.
Researchers identified microglia as key immune cells protecting the brain from airborne viral infections, limiting damage to neurons. CD8 T cells engaged microglia to present virus particles, triggering an antiviral response without killing neurons.
Researchers from the University of Nottingham have created a novel solution to combat fungi using a non-toxic polymer coating that reduces attachment of fungal pathogens. The coating, made from (meth)acrylate polymers, has shown up to 100% reduction in fungal growth on various surfaces.
A new study found that high uric acid levels protect female lung function from decline with age or disease. Women with lower female hormone levels are more likely to benefit from this antioxidant effect.
Researchers have discovered a new disease that affects the same chloride channel as cystic fibrosis, potentially leading to improved treatment options. The study found that patients with this disease do not develop respiratory symptoms, suggesting a possible treatment target for cystic fibrosis.
The American Medical Directors Association published recommendations to reduce COVID-19 spread in nursing homes and long-term care facilities. The guidelines include COVID-specific units, daily screenings, and staff testing to prevent outbreaks.
Researchers project that American lobster will move further offshore and sea scallops will shift north in the coming decades. The study's findings pose fishery management challenges as changing habitats can impact where species can be caught and who has access to them.
The May 2020 nTIDE report shows an increase in employment-to-population ratio and labor force participation rate for working-age people with disabilities, up 5.3% and 4.6%, respectively. This uptick may indicate people with disabilities returning to work as restrictions ease.
An international team developed a sophisticated experimental technique at BESSY II to observe the formation of a metallic conduction band in electrolytes. The team analyzed the process using soft X-rays and combined it with theoretical predictions, making this a significant contribution to fundamental understanding.
Researchers found that T cells increase their metabolism to survive, contradicting previous assumptions about immune function. The study suggests that targeted interventions like vaccines or immunotherapies could boost T cell immunity in the elderly.
Researchers demonstrate that introducing dislocations through ion implantation can increase the thermal stability of photoluminescence in silicon. By optimizing implantation conditions, they achieved measurable levels of luminescence at room temperature.
Researchers at Boston Children's Hospital successfully recreate human skin with hair, nerves, and fat using a novel culture technique. The breakthrough has the potential to revolutionize wound treatment, burn care, and cosmetics testing, as well as aid in the development of new treatments for diseases such as Merkel cell carcinoma.
Avesta Sasan is exploring the design space of SAT-hard obfuscation solutions and building provable methods to tradeoff power, performance, and area versus security. The research has potential to introduce new metrics for evaluating obfuscation effectiveness.
Elsevier has launched a free access special issue of curated content focused on biodiversity, highlighting the urgent need for climate action and protecting the planet. The collection features over 60 carefully selected journal articles and book chapters supporting the United Nations Sustainable Development Goals.
A joint project between TU Dresden and UNU-FLORES uses modeling to simulate observed changes in soil structure due to agricultural management, aiming to improve hydrological models. Field experiments showed that tillage had little effect on soil structure over time, while direct sowing improved water retention.
A new study reveals that deep water masses in the eastern Mediterranean can reach up to 70% of the western basin, contradicting classic hypotheses. The research uses rare earth elements and neodymium isotopes as conservative tracers to reconstruct the oceanographic structure of the Mediterranean basins.
A study found that more than half of COVID-19 ICU patients developed clinically significant blood clots undetected by routine screenings. Researchers recommend using thromboelastography (TEG) tests to identify these patients and administer additional blood thinners.
Focal segmental glomerulosclerosis is a common cause of steroid-resistant nephrotic syndrome, which may progress to end-stage renal disease. Researchers found that the protein MafB plays a protective role in FSGS, with increased levels of MafB reducing kidney damage and nephrotic syndrome.
The program aims to promote pro-health attitudes and behaviors, reduce prescription drug abuse and concurrent substance use, and enhance protective factors by building social and relationship skills. The large-scale randomized controlled trial will evaluate the program in 40 high schools across the US.
A recent study found that COVID-19 patients with kidney disease have a poor prognosis and increased risk of in-hospital death. The study also showed that the kidneys are a target organ for the virus, with viral load detected in renal tubules and glomerular cells.
A University of Colorado Cancer Center study shows cord blood transplants to be comparable to matched sibling donors in terms of survival outcomes, with significantly fewer complications due to chronic graft-versus-host disease. Cord blood patients also experienced a lower rate of relapse in certain populations.
Clinical genetics services are struggling to cope with the influx of direct-to-consumer (DTC) genetic testing referrals, with many GPs ill-equipped to interpret results. The lack of resources and funding is exacerbating the issue, with only 10% of DTC test results validated.
A research team from the University of Göttingen has successfully harnessed the 'whispering gallery' effect to control electron beams using light. This breakthrough enables new possibilities for quantum technologies in nanoscale sensing and microscopy.
Hospitalized COVID-19 patients with diabetes require comprehensive glucose management to minimize complications and death. The new guidance emphasizes the importance of limiting direct contact between clinicians and patients, using remote monitoring devices, and considering diabetes self-management for knowledgeable patients.
A new study examines ventilation and medication strategies to prevent psychological trauma in COVID-19 ARDS survivors. Researchers found that opiates are the most reliable agent for relieving air hunger, while sedatives often do not alleviate shortness of breath.
Researchers found that blocking Bruton tyrosine kinase (BTK) protein with acalabrutinib reduced inflammation and improved breathing in patients with severe COVID-19. The study suggests a potential new treatment approach for hospitalized patients with low blood-oxygen levels and evidence of inflammation.
Researchers at the University of Colorado Boulder have developed a new method for smart window technology that uses reversible metal electrodeposition to control tinting. The process is cheaper, more effective, and more durable than current options on the market.
A recent study published in Annals of Internal Medicine explores the disproportionate impact of COVID-19 on ethnic minority communities, highlighting existing disparities in healthcare access and treatment. The authors offer a resilience approach to addressing these disparities, drawing parallels with the 1918 influenza pandemic.
A study by Chinese researchers suggests that fencing is necessary in severely overgrazed areas but short-term fencing options should be considered. The authors propose encouraging traditional free grazing practices and removing existing long-term fences to benefit wildlife.
A study of COVID-19 cases among dialysis patients in Spain found a significantly higher rate of infection and mortality compared to the general population. The mortality rate among these patients was found to be influenced by factors such as age, lymphopenia, and elevated LDH levels.
Researchers discovered a link between NMDA receptor dysfunction and sleep spindle deficit in schizophrenia. Medicines targeting these receptors may help treat psychiatric disorders, such as psychosis.