A new AI-based device has been developed to help diagnose aggressive posterior retinopathy of prematurity (AP-ROP) in newborns. The study found that infants who developed AP-ROP were more premature and had lower birth weights, highlighting the need for early detection and monitoring.
A new experimental platform for cancer diagnostics, prognoses, and testing cancer drugs has been developed by analyzing the extracellular matrix of tumor tissues. The platform uses protein fibers surrounding cells to predict disease risk and potential treatment efficacy in various patients with different types of cancers.
Research on over 20,000 online tasks found a significant and persistent gender pay gap despite the absence of overt discrimination. Women's hourly earnings were consistently lower than men's, with task completion speed accounting for some of the gap.
Researchers found that Neanderthals in Southern Siberia originated from various European populations, including those from Central and Eastern Europe. The study used DNA analysis of Neanderthal bones and sediments to reconstruct the migration route.
A new study from Michigan State University and Rutgers University reveals that five to 10 minutes are added to each surgery due to unplanned supplies, resulting in nearly $28 million annually in unnecessary costs. Implementing standardized planning processes for medical supplies can significantly reduce these waste costs.
Researchers have developed micromotors with three engines that can be controlled separately using chemical fuel, magnets, and light. The new micromotors offer a 'myriad of controllable propulsion behaviors' and can travel at high speeds through viscous fluids like saliva and blood.
Researchers at Utah State University developed a computer model to help manage wetland, floodplain and aquatic habitats. The Watershed Area of Suitable Habitat systems model, known as WASH, identifies optimal water allocation strategies to improve habitat quality and area.
A study published in Acta Obstetricia et Gynecologica Scandinavica found that women who had late abortions experienced a higher risk of extremely preterm birth. The research included over 418,000 first-time mothers and observed an increased risk of very low birthweight among those with late abortion(s) compared to early abortion(s).
A new study by UCF predicts that Canaveral National Seashore will experience the greatest impact from sea level rise and hurricanes, with a loss of about 1% of its loggerhead habitat by 2100. The study used a new method to calculate current and future sea turtle nesting areas, which can help the National Park Service manage resources.
Research published in the British Journal of Dermatology found that bereaved individuals have a 17% higher risk of dying from melanoma compared to non-bereaved persons. Those who had lost a partner were also 12% less likely to be diagnosed with melanoma, highlighting the importance of skin checks for early detection and improved survival.
A systematic review suggests that dental teams can play a vital role in identifying individuals at high risk of developing Type 2 diabetes. By using risk assessment tools and point-of-care blood testing, dental professionals can help detect early signs of the condition, potentially leading to better management and outcomes for patients.
A pilot study at USC found that an MAO inhibitor called phenelzine can help patients with recurrent prostate cancer by disrupting tumor growth pathways. The drug has fewer side effects compared to standard hormone therapy treatments.
The nanoscale spectroscopy review highlights the potential of luminescent nanoparticles in diverse areas such as imaging, biomarker detection and data storage. The field aims to understand the properties of artificial atoms to control and tailor them for specific applications.
A new trial led by Beth Israel Deaconess Medical Center found that platinum-based therapy was not superior to standard chemotherapy in treating patients with BRCA mutations. The study, known as INFORM, compared the efficacy of cisplatin to a standard treatment regimen in patients with breast cancer.
The City of Hope's innovative platform enables researchers to access and analyze the data from the California Teachers Study, a 25-year study on cancer, heart conditions, and Alzheimer's disease. This move aims to fast-track scientific discoveries and improve quality of life for people worldwide.
Researchers from ETH Zürich found that single-family households with behavioral change can achieve total self-sufficiency by 2050. However, multi-family buildings require advancements in photovoltaic technology to reach the same level of energy independence.
A new regenerative peripheral nerve interface (RPNI) technology has been developed to improve the control and precision of prosthetic hands for upper limb amputees. The RPNIs allowed participants to perform complex finger and thumb movements with high accuracy and worked for up to 300 days without requiring recalibration.
Researchers at UC San Diego create an inducible quorum sensing system that allows for precise control of single and multiple bacterial populations, regulated by p-coumaric acid. This new genetic circuit enables better control over tasks such as drug delivery and bioproduction.
Use of antibiotics during infancy may increase children's risk of becoming overweight or obese, while prenatal antibiotic use does not appear to affect weight in subsequent years. Investigators analyzed 23 studies involving over 1.2 million participants and found no link between prenatal antibiotic use and childhood obesity.
A new study found that vampire bats' social relationships change differently depending on the type of behavior and relationship. The lead author injected the bats with a bacterial extract to make them feel sick without harming their health, observing how it affected their social interactions.
A study of 170 species found that waves and tides have a bigger impact on marine life in Swansea Bay than human activity. This comprehensive picture will help planners understand the Bay's ecosystem and make informed decisions about ecological impact.
A study by University of South Australia Adjunct Professor Jan de Jonge found that obsessively passionate runners are more likely to suffer from running-related injuries. In contrast, runners who maintain a harmonious balance between running and other activities report fewer injuries.
A recent study by Cornell University researchers found that motor vehicles are the main cause of blocking access to other travelers on city streets, with a higher noncompliance rate (24.7%) compared to scooters and bikes (0.8%). The study suggests that cities should rethink their parking policies in response to the rise of technology-e...
Researchers found that destroying 25% of a one-hectare Atlantic rainforest fragment can raise the local temperature by 1°C. Clear-cutting the entire fragment would increase temperatures by up to 4°C, threatening the biome's carbon balance.
Scientists at Fred Hutchinson Cancer Center discovered a mini-protein in scorpion venom that rapidly accumulates in joint cartilage, allowing it to deliver steroids and other drugs directly to the affected area. This approach may potentially improve the safety of arthritis treatment by reducing systemic side effects.
A study identified dozens of new mutations in the DDX3X gene, critical for brain development, and found that half caused loss of function while others disrupted its normal functioning. The research provides insight into how the gene functions normally and may lead to potential therapies.
A team of researchers from NYU Tandon and Canada have developed a machine learning model called PHTNet, which enables robots to accurately predict and compensate for hand tremors in patients with Parkinson's disease. The model has been tested on a dataset of 81 patients and reported a 95% confidence rate over 24,300 samples.
A new study finds that domestication of plants fostered cooperation among people, but also saw the rise of organized intergroup violence. As farming developed, groups aggregated and lived cooperatively in high-quality locations, but this led to a spike in trophy-taking violence.
CurveBoards enable easier testing of circuit functions and user interactions with products like smart devices and flexible electronics. The custom-designed objects merge form and function testing in early prototyping stages, improving the overall prototyping experience.
A new study by the University of Southampton found that older women with obesity are at a higher risk of prolonged sickness absence or losing their jobs due to health reasons. Women with severe obesity were almost three times as likely to lose their job because of their health.
The discovery of Puccinia abrupta var. partheniicola, or winter rust, provides a second natural enemy to combat parthenium, which is aggressively spreading and causing severe harm to humans and livestock. The presence of this biological control could significantly reduce biomass and seed production of the weed.
Researchers from Uppsala University have developed new indoor photovoltaic cells that can harness and convert indoor light into electricity, enabling self-powered IoT devices.
Researchers developed a new CAR T cell therapy using chlorotoxin, a component of scorpion venom, to target glioblastoma cells. The therapy showed promise in killing tumor cells while ignoring healthy tissue.
A Rutgers study found that middle school football players who wore padded helmets and used safe tackling and blocking techniques had no concussions during a 20-practice, seven-game season. The study's results suggest that the use of Guardian Caps and age of participants may have contributed to the low number of impacts recorded.
The PCORnet Bariatric Study's findings provide a more complete picture of the comparative benefits and risks of Roux-en-Y gastric bypass and sleeve gastrectomy. Patients with severe obesity can now make informed decisions about weight-loss surgery based on individual circumstances and preferences.
Researchers at NYU Langone Health discovered a cell defense mechanism that uses tiny, protein-coated packages called exosomes to bind to and neutralize bacterial toxins. This 'soaking up' of toxins helps keep cells safe from infection.
Researchers at INRS and McGill University developed a method to draw molecular patterns on the surface of quantum materials using macrocycles, changing their optical, magnetic, and electrical properties. This technique has potential applications for electronic devices and biosensing.
Experts debate nationalizing the pharmaceutical sector to improve public health priorities, address extortionate pricing, and ensure patient access to new advanced drugs. Mariana Mazzucato and Henry Lishi Li propose a government-provided quality-assured medicine option that co-exists with private sector products.
Yale scientists have discovered the molecular mechanisms that trigger metabolic imbalance between glucose production and energy utilization in the liver. They found that a protein called INSP3R1 regulates both gluconeogenesis and fat oxidation in response to glucagon, providing new insights into glucagon biology.
Scientists used XSEDE-allocated supercomputers to study ion transport through nanoporous membranes. Advanced path sampling techniques captured the kinetics of solute transport, revealing a previously unknown mechanism called induced charge anisotropy that affects ion movement.
Establishing an inducible BCL6 knock-out model allows studying the phenotype of BCL6 loss in DLBCL xenografts in vivo. The study demonstrates significant tumor growth inhibition and initial tumor stasis followed by slow tumor growth kinetics upon treatment with BCL6 degraders.
Researchers have developed a new type of nanoelectromechanical relay enabling reliable high-temperature, non-volatile memory. The invention is crucial for all-electric vehicles and more-electric aircraft requiring electronics that can operate in extreme temperatures with high energy efficiency.
A randomized clinical trial in 60 urban workplaces in China found that a wellness program with hypertension management component significantly improved blood pressure control among employees. The program reduced systolic blood pressure by 3.5 mmHg and diastolic blood pressure by 2.5 mmHg compared to usual care.
Researchers examined associations between two common weight-loss surgeries and type 2 diabetes outcomes, finding improved glycemic control and weight loss after five years. The study included 9,700 adults who underwent Roux-en-Y gastric bypass or sleeve gastrectomy, suggesting these procedures may help achieve diabetes remission.
A study of 1,177 mother-infant pairs found exclusive breastfeeding for the first 3 months linked with a lower risk of respiratory allergies and asthma. Breastfeeding duration was insufficient to reduce the risk if not accompanied by family history of asthma.
A new study published in Clinical Pediatrics found that young children from low-income homes whose mothers used toxic household chemicals frequently showed delays in language development and scored lower on cognitive tests. The researchers analyzed data from 190 families and found no link between neighborhood pollution, mold, or pestic...
Researchers at Baycrest's Rotman Research Institute found that participants' eye movement patterns could predict mistakes in memory. They used an innovative eye tracking technique to map the participants' eye movements and observe pattern completion.
Researchers developed oscillating catalyst technology that accelerates chemical reactions without side reactions, improving performance and cost-efficiency. This breakthrough has the potential to reduce waste by thousands of tons annually and transform the way chemicals are manufactured.
Researchers have achieved a groundbreaking milestone in treating inherited blindness by using CRISPR gene editing within the human body. The BRILLIANCE clinical trial aims to repair mutations causing Leber congenital amaurosis type 10, a rare form of blindness. This permanent approach avoids passing on genetic changes to offspring.
A special edition of Early Childhood Research Quarterly presents 18 language-intervention research studies on the 'word gap,' which documents significant language disparities in young children. The research highlights the need for targeted interventions with parents, educators, and healthcare providers to address these gaps.
A new study found that high blood pressure in young adulthood is associated with significant declines in cognitive function and gait in midlife. The research, published in Circulation, suggests that treating high blood pressure earlier may prevent future cognitive decline and mobility issues.
New research identifies NMT1 and NMT2 enzymes as regulators of the ARF6 GTPase cycle, allowing scientists to control cell signaling and potentially treat diseases such as cancer and viral infections.
A population-based study found that young immigrants and refugees in Ontario, Canada, are at higher risk of experiencing violent assault compared to nonimmigrant youth. The study used linked health and administrative databases to analyze the risk of violent assault among young immigrants and refugees aged 10-24.
A study of over 2,800 Americans aged 50+ found that lonely individuals experience more burdensome symptoms at the end of life and receive more intense care. They are also more likely to die in nursing homes and use life support.
A team of researchers has identified a novel cybersecurity approach called SymTCP to enhance the effectiveness and timeliness of protection against attacks on Army systems. The approach uses symbolic execution to explore the state of TCP implementation and identify ways to reach critical points in the code.
A new class of antimalarial compounds has been developed by Australian and US researchers, targeting a previously unexplored parasite pathway. The compounds have shown effectiveness against different species of malaria parasites, including Plasmodium falciparum, at multiple stages of the parasite lifecycle.
Experts from UT Southwestern Medical Center suggest integrating travel history into routine medical assessments to identify emerging infectious diseases and prevent further transmission. This simple yet targeted approach can help put infectious symptoms in context for physicians and caregiver teams.
Researchers at Penn State developed a new method to predict the temperature when plastics change from supple to brittle, which could accelerate the development of flexible electronics. The study found that a simple relationship between chemical structure and glass transition temperature can be used to predict embrittlement point.
A study published in Cancer Epidemiology, Biomarkers & Prevention found that young women with breast cancer experience substantial financial difficulties after diagnosis, even if they have stable jobs and insurance coverage. The study highlights the need for better financial planning and awareness of the costs associated with cancer care.
A large US-based observational study found no association between moderate egg intake and increased cardiovascular disease risk. Egg consumption was not linked to higher rates of heart attacks, strokes, or coronary heart disease. However, replacing eggs with processed red meat may be associated with an increased CVD risk.