Pancreatic cancer cells use nerve growth factor to signal nerves to grow into dense tumors and secrete nutrients like serine. This allows the cancer cells to multiply despite nutrient starvation, highlighting a unique adaptation that contributes to their deadliness.
Researchers have identified a new and evolutionarily conserved pathway responsible for silencing genes in mammalian cells. BAHCC1 protein is involved in the Polycomb pathway, which generates a chemical tag to silence genes, and its high expression is linked to leukemia, challenging current understanding of gene silencing.
Mice sleep-deprived for research show increased preference for lower doses of cocaine, while rested mice do not. Blocking the orexin system reduces the increased cocaine preference driven by sleep deprivation.
Researchers found evidence of mounted horseback riding in ancient China, with signs of chronic use of saddles and metal bits on horse skeletons. The discovery suggests that the region played a crucial role in spreading equestrianism to early Chinese civilizations.
New research suggests that a 2°C warming would release 230 billion tonnes of carbon from the world's soil, more than four times China's total emissions over 100 years. This 'positive feedback' effect contributes to further climate change.
A new study reveals that mammals developed social behavior much earlier than previously thought, interacting with dinosaurs in tightly packed clusters. The fossils, which are about 75.5 million years old, show evidence of multiple mature adults and subadults congregating, indicating a complex social structure.
Researchers found that small loans during the lean season led to higher quality of life, increased agricultural output, and greater wages. The study's results validated the importance of seasonal variability to rural farmers' livelihoods, highlighting the need for economic interventions that account for this factor.
Researchers used microfluidic devices to study the interaction between viruses and cell membranes, revealing high-resolution understanding of electric shifts happening at the surface. The technique showed that glycine can interrupt capsid formation for replicated viruses within the cell.
Researchers have developed a graphene-organic heterojunction transistor that can modulate photocurrent speed, magnitude, and direction using light. The device utilizes the effective exciton thickness limitation of an intermediate organic transport layer to achieve logic reversal under optical modulation.
Researchers at the Heidelberg Max Planck Institute for Nuclear Physics have investigated ultrafast fragmentation of hydrogen molecules in intense laser fields using a new method. They used the rotation of the molecule as an internal clock to measure the timing of the reaction triggered by a second laser pulse.
A KAUST team has developed a printable ink with high conductivity and transparency for use in solar panels and novel electromagnetic wave blocking. The ink's performance was demonstrated in a frequency selective surface, showing decent reflection across multiple frequencies and polarization insensitive results.
Researchers analyzed long-term phytoplankton data to understand climate change effects on ocean productivity and biodiversity. The study found a significant increase in warm-water species, suggesting an adaptation advantage under changing conditions.
A research team at POSTECH developed a machine learning technique that uses transcriptome information from artificial organoids to predict anti-cancer drug response. This method increases predictive accuracy by selecting only relevant biomarkers, which was previously limited by false signals in conventional machine learning.
Researchers at KAUST developed a new material that significantly improves the energy density of supercapacitors, enabling quick bursts of energy. The material uses covalent organic frameworks (COFs) with carefully selected molecular functional groups to overcome conductivity limitations.
Researchers at the University of Göttingen found that beetle larvae start using their brains before they are fully formed, defying conventional wisdom on insect intelligence. The study revealed that key parts of the brain's central complex are active in the larva, allowing it to orient itself in its environment.
The new photodetector achieves ultrasensitive detection, stable operation under extreme conditions, and ultrabroad spectrum detection exceeding 10μm.
The survey found that spine surgery had the highest number of medical malpractice suits among neurosurgeons. Fear of lawsuits influences their practice, with defensive medicine being a common response. The study highlights the need for transparent communication, better informed consent forms, and fair compensation to patients.
Scientists have discovered a key mechanism behind SINEUPs, which can amplify protein production by messenger RNAs. The research provides new insights into how these functional non-coding RNAs work and their potential to treat diseases caused by insufficient protein synthesis.