The study compared survival rates in patients undergoing surgery for brain metastases with conventional white light microscopy versus 5-ALA fluorescence microscopy. The results showed no significant difference in local recurrence or mortality between the two groups, but radiotherapy was strongly associated with improved survival.
Researchers at Flinders University found that students' emotional resilience is linked to their chances of being victimized, with less resilient students more likely to suffer from harassment. Higher levels of resilience and wellbeing tended to go with being bullied less often, being a boy, and being younger.
Researchers found that Indian and Pakistani women are diagnosed with breast cancer at a younger age and at more advanced stages than non-Hispanic white women. The study highlights the need for culturally relevant strategies to improve preventive healthcare in this growing population.
A new study reveals that countries relying heavily on global trade are more vulnerable to resource scarcity, especially in the face of climate change. The research highlights the need for a systemic approach to examining pressures on water, energy, and land resources.
Social determinants like discrimination, depression, and mistrust predict patient-reported quality of life in kidney transplant patients. Lower medical mistrust leads to greater patient satisfaction with clinical services.
The KRYSTAL-1 phase I/II clinical trial has shown that adagrasib can shrink tumours and is well-tolerated by patients with non-small cell lung cancer, colorectal cancer, and other solid tumours. The KRAS G12C mutation affects approximately 14% of lung adenocarcinomas and 4% of colorectal cancers.
Adagrasib achieves objective responses in nearly half of patients with non-small cell lung cancer; encouraging early results are seen in patients with colorectal, pancreatic, and endometrial cancer. The agent targets KRAS G12C mutation, leading to manageable side effects.
A study analyzing 60,229 patients found that Black patients are less likely to be referred for transplantation and more likely to receive a transplant after referral, but ultimately less likely to receive a transplant overall. Racial disparities in the transplant process emerge at listing stage and persist through organ allocation
A new 'next generation' BRAF inhibitor, PLX8394, has shown promising results in an early patient trial for treating various types of cancer. The treatment, taken with cobicistat, resulted in a partial response in 22% of patients, including those with glioma and bowel cancer.