A recent study predicts that climate change in South Africa will lead to a 20% decrease in per capita GDP by the end of the century. The researchers analyzed data on temperature changes and labor availability, finding that low-skilled workers are disproportionately affected, leading to a closing wage gap but reduced overall output.
Researchers found that genetic mutations, such as IKZF1 deletion and CRLF2 translocations, occur more frequently in Hispanic and Latino children with B-cell acute lymphoblastic leukemia (B-ALL), leading to poorer outcomes. A novel therapeutic drug combination may help address this disparity.
Engineers at MIT designed a bioadhesive patch inspired by origami that can seal internal wounds and tissues. The patch, made from three layers, resists contamination and biodegrades over time.
A new study suggests that starting adulthood with a normal weight and gradually gaining pounds later in life can increase the probability of survival. In contrast, those who start as obese or stay at an unhealthy weight throughout their lives tend to have the lowest survival rates.
Researchers have discovered that pollinator host-switching and hybridization are common features of fig-wasp coevolution, contradicting the traditional view. The study analyzed genomes from 15 fig species and found widespread hybridization events with associated host-switches among pollinators.
A new study published in Risk Analysis found that fear-based Virtual Reality films depicting violent collisions lead to increased risk-taking among young drivers. In contrast, positively framed VR films result in the greatest reduction in risky driving behavior. This suggests that a positive approach may be more effective in promoting ...
A new study from Boston University School of Medicine has discovered a drug that can inhibit the growth and spread of melanoma in human cells and experimental models. The researchers found that this drug acts through a specific pathway to prevent cancer cell growth and metastasis.
A new study finds that households' ability to glean seafood in rough weather is influenced by shallow habitat area and type. This highlights the importance of context-specific understanding of dynamic coastal livelihoods for sustainable fisheries management.
A new wearable device collects biofluids such as tears and saliva to analyze conditions like oral ulcers, oral cancer, and eye infections on a rapid, continuous basis. The sensors also administer medicine with microneedles through the skin, offering improved treatment options for patients.
The Holonyak lab team has developed a simple, 15-minute sample-to-answer test for detecting COVID-19 antibodies at a cost of less than $2 per test. This low-cost test demonstrates great potential for widespread use in various settings, including clinics and physician offices.
This study elucidates the molecular mechanism of 2-methoxyestradiol (2MeOE2) inducing apoptosis in ovarian tumors through PKCδ signaling. The findings suggest that 2MeOE2 activates PKCδ, leading to γH2Ax expression and apoptotic histone modifications, thereby driving apoptosis in ovarian cancer cells.
Researchers studied gift-giving dynamics in multi-giver settings and found recipients prioritize thoughtfulness over relative gift value. Gift givers incorrectly assume the recipient's focus is on comparative gift value, leading to unnecessary spending or skipping gift-giving occasions.
Researchers analyzed near-real-time social media data to understand public perceptions of COVID-19. The study found that Trump's infected status significantly impacted public attitudes towards the pandemic, with some people becoming more skeptical of COVID-19 measures.
A new study found that the revised concussion guidelines led to a significant reduction in symptom duration among young athletes. The adoption of active rest, recognizing pre-existing conditions, and educating athletes about recovery improved outcomes, with male athletes experiencing a median duration drop from 11 to 5 days and female ...
A study published in EMBO Molecular Medicine reveals that alterations in lamin B1 protein contribute to neurodegeneration in Huntington's disease. The researchers used innovative techniques like FANSI and ChIP-sequencing to analyze the impact of lamin B1 levels on gene transcription.
Researchers have developed a new brain stimulation technique that can predict individual responses to treatment, paving the way for personalized therapies. The technique uses machine-learning models to analyze brain activity across multiple regions and adjust stimulation doses in real-time.
Astrophysicists at MIT have discovered an extended dark matter halo around Tucana II, a primitive ultrafaint dwarf galaxy. The halo is estimated to be three to five times more massive than previously thought, implying that the first galaxies in the universe were likely larger and more massive.
A new study found that traffic noise and man-made sounds significantly impact the mating choices of female field crickets. In noisy environments, females are unable to detect differences in male quality, leading to a reduction in offspring viability.
Researchers found that inhaling unfragmented hyaluronan improves lung function in patients with severe COPD, shortening hospital stays and decreasing breathing support needs. The treatment also aids mucus transport and promotes recovery.
A new study optimizes LIBS for analyzing hydrogen isotopes in nuclear reactor materials, enabling faster and more accurate measurements. The researchers found that combining ultrafast laser pulses with specific environmental conditions improves the technique's performance.
A new deep-learning model has identified at least 10 compounds that may hold promise as treatments for COVID-19, including approved drugs like cyclosporine and anidulafungin. The model uses artificial intelligence to predict gene expression values for new chemicals, providing a valuable tool for pharmaceutical and clinical researchers.
Researchers found no evidence to support the claim that rare birds draw more birders, leading to additional discoveries. The study examined eBird data and mega-rarity sightings over 10 years, concluding little support for the Patagonia Picnic Table Effect.
Research published in the American Heart Association's Circulation Journal found that women with a history of gestational diabetes during pregnancy have a two-fold higher risk of coronary artery calcification, a strong predictor of heart disease. Attaining healthy blood sugar levels after pregnancy does not decrease this risk.
Students from lower socio-economic groups are less likely to participate in sport or physical activity at university due to cost and time constraints. Those with prior experience in sport before starting university are more likely to continue participating.
Researchers found that patients with mild COVID-19 symptoms have an early induction of IFN-γ secreting SARS-CoV-2 specific T cells, which plays a crucial role in rapid viral control and disease clearance. The study's findings have implications for vaccine design and monitoring.
Research into INNA-X shows it is effective against rhinovirus, the main cause of the common cold, reducing viral load and inflammation. The nasal spray works by stimulating the innate immune system, making it harder for viruses to take hold.
The study of Tiktaalik roseae reveals an intermediate stage in vertebrate evolution, shifting from suction-based to biting-based feeding strategies. The fossil's anatomy suggests a synergistic feeding strategy combining snapping and suction, potentially leading to the development of four-limbed animals.
Researchers analyze molecular dynamics of proposed COVID-19 drug candidates to understand their interactions with target proteins in human cells. They found that certain parts of the molecules can move more easily once hydrated, which could influence how efficiently a drug takes on shapes associated with different biological functions.
A 15-year experiment on Arctic shrubs in Greenland sheds light on species diversity and co-occurrence versus exclusion, with important implications for carbon sequestration. The study reveals trends related to carbon exchange as the Arctic becomes greener and browner due to climate change.
Researchers at the University of Sydney and Microsoft have created a single chip that can generate control signals for thousands of qubits, revolutionizing quantum computing. This breakthrough resolves a key limitation to scaling up quantum machines, paving the way for more powerful computers.
Researchers find that hanging black rhinoceroses upside down improves ventilation to a small degree, enhancing the safety of these animals during capture and anesthesia. The study's findings have significant implications for conservation efforts in remote areas where helicopter-assisted aerial transport is often used.
The study describes a dynamic link between correct protein folding and amyloid fibril formation, highlighting the threshold of supersaturation that must be overcome. Supersaturation is a fundamental concept that advances the field of protein folding and may contribute to therapeutic strategies for neurodegenerative diseases.
NYU College of Dentistry has been awarded a $1.9 million NIH grant to study the molecular mechanisms underlying mitochondrial permeability transition, a phenomenon that causes tissue damage during strokes and heart attacks. The research aims to develop new drugs that can protect against cell death and tissue damage.
Researchers at Mayo Clinic have developed an AI-powered mobile EKG device that can rapidly and accurately determine a patient's QTc, identifying those at risk of sudden cardiac death from congenital long QT syndrome or drug-induced QT prolongation. The device achieved high sensitivity and specificity in detecting clinically meaningful ...
Researchers found that gut bacteria use enzymes to modify and detoxify bile salts, which can be toxic to bacteria. This interaction affects bacterial fitness and competition in the gut ecosystem.
A new protein has been developed that acts as a decoy to prevent the COVID-19 infection from entering human cells. The protein is a modified variant of ACE2, which intercepts the S spike of the coronavirus and fools it into binding to it rather than the real receptor.
The researcher aims to identify common mechanisms among persister cells and their unique metabolic processes. The goal is to develop new strategies for understanding and combating bacterial persistence.
Researchers find immense biohydrocarbon cycle in ocean, with marine cyanobacteria producing pentadecane at rates of 300-600 million metric tons per year. The cycle plays a crucial role in the ocean's response to oil spills and could potentially prime the ocean for cleanup.
Scientists at the Weizmann Institute of Science mapped the entire stress axis in detail, identifying 21,723 cells along the route. They found significant alterations in gene expression and cell changes, particularly in the adrenal glands, which play a crucial role in the stress response.
A global study shows that human disturbances, such as hunting and recreation, trigger significant changes in animal movement, forcing species to travel 35% more or less than usual. This widespread impact threatens biodiversity and ecosystem processes, highlighting the need for conservation efforts.
Scientists have discovered a way to create materials that can snap and reset themselves, moving without the need for motors or external power. This breakthrough could enable future military robots to operate independently, reducing reliance on batteries and motors.
A study published in JAMA Neurology found that college football players suffer from high frequencies of concussions and repetitive head impacts over several seasons. The researchers identified patterns of injury and highlighted the need for further research to address the long-term effects on player health.
Scientists have synthesized a biomolecule that resembles a natural anisotropic dual-stimuli-responsive channel, allowing for the creation of advanced biosensors and drug alternatives. The channel, called VF, can be activated by two specific stimuli dependent on its biased orientation within the membrane.
A study published in Frontiers in Immunology found that Brazilians of African descent are less likely to find a donor in the National Register of Voluntary Bone Marrow Donors, with an up to 60% reduction in chances. The lack of representation and genetic diversity makes it harder for individuals with African ancestry to find compatible...
New analysis of satellite data reveals Antarctica's ice melts at different rates each year, affecting sea level rise predictions. The study suggests that models used to predict sea-level change should reflect the dynamic nature of ice sheet changes.
A Swedish study found COVID-19 intensive care mortality rates were lower compared to other countries, despite higher comorbidities. The study suggests process and organisational factors contributed to the better outcomes.
Physicists have designed a new method to calculate atomic nucleus properties incredibly quickly using emulation and eigenvector continuation. This approach sheds new light on topics like neutron stars and nuclear decay.
Researchers have sequenced over 700 novel microbial genomes from the gut microbiome of a goat, discovering that fungi play a disproportionate role in biomass degradation. The study also found that fungi are more efficient at producing methane, a potential game-changer for renewable energy production.
Lung cancer is a leading cause of death in Singapore and the world, with Asian populations exhibiting distinct genetic alterations. The World Conference on Lung Cancer Singapore presented new data on EGFR mutation and TKI-drug resistance, highlighting the need for targeted treatment approaches.
Researchers from the University of Nottingham have demonstrated that backreaction can be simulated in a laboratory experiment using a specially designed water tank. The study found that waves sent into an analogue black hole significantly changed its properties, with effects visible to the eye.
Between 2010 and 2017, US stimulant-associated deaths rose substantially, driven primarily by cocaine use. Medical stimulants also contributed to the increase, suggesting a broader public health concern.
A new study by CMCC Foundation investigates sustainable land management options to reduce GHG emissions from livestock, which contribute to 60% of agricultural emissions in Europe. The approach aims to enhance carbon sink function in soils and biomass through targeted land-use strategies.
Researchers successfully transmit uncompressed 8K video wirelessly using terahertz waves, enabling low latency and low power consumption. The technology is expected to accelerate research and development for the realization of 6G mobile communication standard.
Patients with non-small cell lung cancer who enrolled in a phase III early-stage trial showed a high rate of smoking reduction and cessation following study entry. Smoking rates were significantly lower among never-smokers, leading to improved overall survival compared to smokers.
A new RAND Corporation study found that people who struggle to pay rent or are forced to move due to financial issues sleep significantly less than their peers. The study of 1,046 participants in California's welfare program revealed a 22-minute and 32-minute reduction in sleep duration for those facing housing insecurity.
A new University of Washington study found that bleeding gums on gentle probing and retinal hemorrhaging are associated with low vitamin C levels in the bloodstream. Increasing daily vitamin C intake helped reverse these bleeding issues.
Researchers found that intensive blood pressure lowering is effective in reducing cardiovascular risk, especially in patients exposed to high levels of fine particulate matter. The study suggests that ambient air pollution may influence the benefit of intensive BP lowering.
Ovarian clear cell carcinoma (OCCC) remains a rare subtype with poor prognosis. Simvastatin efficiently controlled OCCC proliferation and migration, demonstrating potential as a candidate drug.
Engineers at Rice University developed a model to quantify the spread of pollutants from failed storage tanks during natural disasters. The model shows that chemicals like benzene and toluene can evaporate and drift with the wind, posing health risks to downwind communities.
Researchers found that an enriched diet and companionship can reduce pain in mice with sickle cell disease by increasing serotonin levels. Duloxetine, an antidepressant boosting serotonin, also showed similar pain-reducing effects.