Scientists at Osaka University have developed an ultrathin silicon membrane with arrays of nanopores that can harness osmotic flow to generate electricity from seawater. The device achieved peak power efficiency of 400 kW/m² and demonstrated optimal configuration for best power generation.
Researchers identified protein levels that were higher or lower than normal in tissues from individuals at different stages of type 2 diabetes. The study found a correlation between metabolic pathway disturbances and disease progression, suggesting new potential causal mechanisms for the disease.
Researchers develop high-safety, long-life lithium metal batteries with a new electrolyte that suppresses dendrite formation. The electrolyte delivers excellent electrochemical performance and offers solutions for building high-performance lithium metal batteries.
Researchers at NYU Grossman School of Medicine have discovered a new treatment approach that suppresses allergic asthma without compromising the body's defenses against flu viruses. The treatment, which targets calcium channels in immune cells, has shown promise in reducing asthmatic inflammation and mucus build-up in mice.
Researchers developed an 'inter-rationality' model, inheriting the limited rationality model, to present an economical alternative for modern societies. The new theory establishes a microeconomic foundation for corporate-level activities in open innovation structures.
A recent study at the Max Planck Institute for Human Cognitive and Brain Sciences found that mothers' postnatal depressive moods can impact their babies' ability to distinguish speech sounds. Mothers in a negative mood tend to use less infant-directed speech, leading to delayed language development in infants.
Researchers identified genes that affect immune system response and replication of SARS-CoV-2 virus. Missing ORF3a/b gene led to milder infections, while missing ORF8 gene worsened lung inflammation. Spike protein severity varied across variants, with mutations in accessory proteins altering clinical presentation.
Researchers at Helmholtz-Zentrum Berlin for Materials and Energy are utilizing X-ray absorption spectroscopy to investigate oxygen evolution in electrocatalysis. This study aims to improve the efficiency of green hydrogen production by developing more stable and cost-effective catalysts.
Nagoya University scientists developed a controller with a sleep mode to procure energy only when needed, reducing the need for storage batteries and capacitors. This innovative solution enables efficient energy saving and promotes the practical application of power packet type energy Internet.
The program cuts the average time it took for new patients to get their first treatment from 97 days to just 41 days, while also allowing more than 1,000 new patients to begin treatments. The system has made significant improvements in efficiency and patient satisfaction, with appointment no-shows dropping by 50%.
A study tracking pediatric body mass index (BMI) before and during the pandemic found a significant increase in BMI rates, with girls experiencing an 11% mean rise. The study also linked increased screen time and family time together to rising BMIs.
Research at LAC+USC Medical Center found a 11% decrease in exclusive breastfeeding and a 4% decrease in any breastfeeding during the COVID-19 pandemic compared to pre-pandemic rates. Hospital staffing changes and access to breastfeeding training may have contributed to these declines.
A new study found that caregivers, particularly women, experience higher odds of health-related vulnerabilities such as food insecurity and financial strain. Caregivers must balance their own lives with those of their dependents, finding ways to care for themselves while dedicating time to caring for loved ones.
The Asthma Health Equity Index identified strong associations between race, ethnicity, and social determinants of health, such as food insecurity, housing instability, and tobacco use. The index has the potential to help healthcare providers identify and address disparities in asthma care.
Researchers discovered consistent fluctuations in vaginal immune-signaling molecules during menstrual cycles, influencing fertility and infectious disease development. This study provides a framework for optimizing vaccine administration to align with the immune system's natural ebbs and flows.
A new study at the Turku PET Centre discovered that shorter daylight hours increase opioid receptor levels in brown fat of rats. This complements previous findings on day length modulating opioid receptor levels in brain emotional circuits.
The study attributes the uptick in injuries to disruption of family routines and stay-at-home orders during pandemic, resulting in decreased helmet use and increased head injuries. The research found a 37% increase in pediatric injuries from 2018 to 2020, with most problematic for publicly insured patients.
A 20-year review of bicycle injuries found over 1 million US children fractured a bone while riding a bike, with most being boys between ages 10-15. The study also showed that nearly 87% of patients with skull fractures were not wearing helmets at the time of injury.
Researchers discovered that animal models with germline alteration rs55705857 developed gliomas significantly faster than those without the alteration. The study offers new insights into tumor formation and may lead to novel therapies targeting this specific change.
Researchers created a breathable underwater movement sensor by applying a thin, slippery coating to conductive fabric, enabling the detection of swimmers in distress. The smart system wirelessly alerts a smartphone app when a swimmer stops moving, indicating potential drowning.
A University of California, Berkeley study found that aging and environment are more important than genetic variation in affecting gene expression. As individuals age, their gene expression profiles diverge, making genetics less useful in predicting which genes are ramped up or down.
A WVU biomedical engineer is working on a rapid diagnostic tool that can detect tick-borne infections such as Lyme disease via a blood sample on a single chip. The tool uses dielectrophoresis and machine-learning to detect diseases within one to two weeks after onset, reducing the risk of hospitalization and chronic conditions.
Researchers from the University of Tsukuba have developed a statistical framework called CCPLS that analyzes spatial gene expression data at single-cell resolution. The study found that neighboring cell types influence gene expression variability in ways that were not previously accounted for by existing methods.
A new study reveals that global warming has doubled the probability of extreme ocean warming events in Japan's marginal seas since the 2000s. The increased occurrence frequency is attributed to human-induced climate changes, with most events linked to global warming.
Researchers developed Pillar-Suspended Bridge (PSB) technology for chiplet integration, enabling improved inter-chip connection density and electrical properties. The technology uses a simple structure with high bonding accuracy and reduces yield problems when scaling up integration.
A large clinical trial found that insulin glargine and liraglutide were superior to other diabetes drugs in controlling blood sugars. The study, published in the New England Journal of Medicine, compared four common medications used to treat type 2 diabetes when added to metformin.
NIH scientists mapped the organization of human retinal cell chromatin, revealing insights into regulation of gene expression and retinal function. The study identified distinct patterns of interaction at retinal genes suggesting how chromatin's 3D organization plays a crucial role in tissue-specific gene regulation.
A new project aims to develop sustainable roses resistant to biotic and abiotic stresses, and have high ornamental quality. The researchers are combining traditional plant breeding with molecular genetics to stack multiple resistance genes into a rose.
The study found that microbial enzymes are essential for the digestion of pectin in leaf beetles, allowing them to access nutrient-rich plant cells. The researchers also discovered that leaf beetle species acquire these enzymes through horizontal gene transfer from other microbes.
A Rutgers-led study of over 2,700 pairs of twins found that adolescent alcohol misuse is associated with poorer life satisfaction, physical symptoms, and self-rated health in midlife. The study's findings suggest that teenage drinking may have long-lasting indirect effects on physical health and well-being.
Researchers found that synthetic turf football fields have a greater impact deceleration compared to natural grass, increasing the risk of injury and concussion. The study's findings suggest that considering safety in sports requires widening our view to include playing surfaces.
A new study re-examines fossil bones from the Nombe Rock Shelter in PNG Highlands and suggests that several large mammal species may have survived for another 40,000 years. The research challenges general assumptions about megafaunal extinction timelines and provides fresh insights into the natural history of PNG.
Researchers develop autonomous navigation strategies for microswimmers, allowing them to navigate optimally in complex environments. These strategies utilize external stimuli, such as light, to guide the microswimmers and improve their performance.
Researchers developed a novel organoid model to study pancreatic cancer cells' growth and arrangement. The model provides insight into the three-dimensional structure of tumors, enabling tracking of individual growth stages, cell divisions, and gene expression patterns.
A new study found that the organization of different types of immune cells within pancreatic tumors is associated with patient outcomes. Immune cells called IL-10+ myelomonocytes tend to be located close to specific T cell types, which may affect cancer treatment responses.
Researchers developed a new global water quality model to assess current and future pollution status of rivers and streams globally. The study found that achieving the SDG target would not be enough to protect surface water quality in some regions, particularly in sub-Saharan Africa and South Asia.
Researchers found chlorobenzenes in a corroded Roman bowl dated to the Late Iron Age, which may pose a threat to archaeological preservation due to pollution in soil. Soil polluted with chlorobenzenes can lead to increased corrosion and damage to ancient artifacts.
A study by Social Psychologist Amy Muise found that intercultural romantic relationships facilitate personal growth through shared perspectives and knowledge. The research also showed that actively sharing cultures and discussing differences is linked to greater cultural awareness and relationship quality.
The COVID-19 pandemic is linked to increased malnutrition risk, as reduced access to food and healthcare worsens nutritional deficiencies. In turn, malnutrition amplifies the spread of infectious diseases, creating a vicious cycle that threatens global health.
Researchers developed a low-cost, simple imaging system using tumor-targeting fluorescent molecules to determine tumor depth. The portable system provides quantitative information about the depth of tumor cells in the body, helping surgeons remove healthy tissue around tumors for better outcomes.
A search of the Cambridge Structural Database found nearly 1,800 conglomerate crystal structures with spontaneous enriched chirality, augmenting synthetic building blocks for medicinal chemists. This discovery introduces a new pool of chiral molecules outside of natural sources, potentially leading to more effective treatments.
A study of 1,270 youths found that attending a high-performing public charter high school was associated with lower rates of substance use disorder and delinquent behaviors. The study also showed that attendance at such schools was linked to better physical health outcomes for males but worse outcomes for females.
Scientists from Paderborn and Ulm universities create a programmable optical quantum memory, enabling the efficient growth of large entangled states. This breakthrough milestone brings researchers closer to practical applications of useful quantum technologies.
A novel COVID-19 vaccine developed by Brazilian scientists combines two SARS-CoV-2 proteins to trigger a cellular immune response. The vaccine, called SpiN, showed promise in animal trials, protecting against three strains of the virus and reducing viral load by up to 50 times.
The journal covers high-quality research and practice-driven advancements in distributed ledger technologies. Featured articles include Byzantine Fault Tolerance, incentivizing data quality, decentralized federated learning, and scalable trustworthy infrastructure.
Researchers have developed a phase diagram that predicts ecosystem stability based on the number of species and interaction strength. The study shows three states of ecological communities, with conditions for moving between them, allowing for the prediction of instability and fluctuations in populations. This work builds on previous f...
A large randomized clinical trial demonstrated Octagam 10% as an efficacious and well-tolerated treatment option for adult dermatomyositis patients. The study showed improved outcomes in patients with this rare disease, providing a much-needed treatment alternative.
Coskun's team has developed SpatialVizScore, a new method that visualizes tumor immunology in cancer tissues to identify patients more likely to respond to immunotherapy. The system looks at the interactions of multiple immune cells, including macrophages with subtypes M1 and M2.
Researchers at CNIO have identified alveolar type II pneumocytes as the primary cell type responsible for developing pulmonary fibrosis. The study reveals that targeting these cells through telomere-based therapy may lead to a breakthrough in treating this debilitating disease.
A team of researchers from Ulsan National Institute of Science and Technology (UNIST) has finally solved the long-standing mystery of contact electrification, a phenomenon that was once humanity's only source of electricity. The study reveals that charge mosaics on contact-electrified dielectrics result from polarity-inverting discharges.
A small test group has shown that using a patient's own cells in combination with regulatory T-lymphocyte and IL-2 treatment can safely and effectively slow or halt the progression of amyotrophic lateral sclerosis (ALS). This treatment approach was found to be tolerable and biologically active over a period of one year.
A 14-year study by the USGS and University of Wyoming found that energy development in mule deer corridors reduces their ability to match foraging with spring green-up. As a result, deer lose out on the best food resources during critical migration periods.
A new study from UCLA found that students who attended high-performing charter schools had a 50% lower rate of alcohol use disorder compared to waitlisted students. Males in the intervention group also reported better physical health and lower obesity rates, while females did not show similar benefits.
Researchers propose a new demand-driven planning scheme for efficient bike path networks in densely populated areas. The approach balances safety preferences and route choice, providing a quantitative assessment of existing and planned network structures.
A team from McGill University has created a database called neuromaps, which combines over 40 existing brain maps to help scientists find correlations between patterns across different brain regions. The tool provides standardized space to view and compare each map, improving reproducibility of results.
Researchers discovered that dormant bacterial spores can evaluate their environment without waking up, using stored electrochemical energy to determine favorable conditions. They found that spores release their energy to perform a computation about their surroundings, similar to how neurons operate in the brain.
Researchers at the University of Basel have discovered a new function of the cerebellum in storing emotional experiences, which is crucial for our survival. The study shows that increased activity in the cerebellum facilitates the storage of information in various areas of the cerebrum, leading to improved memory for emotional events.
Rescue Biomedical's technology detects opioid overdoses and delivers naloxone to reverse them. The NIH grant will help the company complete milestones, including regulatory approval and scaling up manufacturing.
A recently discovered shrine at the Berenike site in Egypt's Eastern desert has provided unprecedented discoveries linked to the presence of the Blemmyes, a nomadic people. The Falcon Shrine contains offerings such as harpoons and cube-shaped statues, as well as a stele with indications related to religious activities.
Researchers at the University of Bern identified new targets for drug development in non-small cell lung cancer, a largely incurable type of cancer. The study focused on long noncoding RNAs, which were found to play a crucial role in NSCLC cell division and tumor growth.