Researchers developed a model to simulate red blood cell destruction in high shear flows, revealing acceleration as a major factor. They recommend adding flow buffers to VADs to reduce hemolysis, aiming to improve hydraulic performance and patient outcomes.
The introduction of fluoroethylene carbonate (FEC) into a poly(1,3-dioxolane)-based polymer electrolyte improves the performance of sodium metal batteries. FEC forms a passivation layer that inhibits side reactions between DOL and the Na metal, reducing interfacial resistance and improving battery overall performance.
The Arizona State University's Quantum Collaborative is a major initiative promoting understanding of advanced quantum technology and forging partnerships to advance it. The collaborative aims to develop a robust talent pipeline for a quantum-enabled economy through certifications, upskilling opportunities, and modified degree programs.
Researchers found that structural racism and insurance barriers limit access to advanced epilepsy care for minority groups in New Jersey. Black patients with private insurance and Medicaid had the lowest EMU admission rates relative to emergency room visits.
A digital twin-based smart healthcare system uses a cascade recurrent convolution neural network (RCNN) architecture to analyze X-ray images and detect COVID-19. The system achieves good accuracy, with a mean average precision rate of 0.94.
A major birth cohort study reveals that children exposed to traumatic events, such as witnessing death or serious injury, are almost twice as likely to develop psychiatric disorders. By age 11, over a third of the children had been exposed to trauma, associated with a wide range of mental health problems.
Researchers found lower calcium and phosphorus concentrations in female primates' bones after giving birth and breastfeeding. The study, which analyzed bone composition over time, shows that reproduction permanently alters the skeleton's dynamic nature.
The analysis found that travel time to abortion facilities in the US rose after Dobbs v Jackson's decision, with closure of 6-week bans increasing delays. The pre-Dobbs period saw more accessible facilities, resulting in shorter estimated travel times.
Researchers at Washington State University developed a new method to measure residual herbicides in fruits, vegetables, and their products using nanoparticles. The test is sensitive enough to detect chemicals down to maximum acceptable levels and is validated using traditional testing methods.
Researchers have developed a preclinical model of appendiceal cancer, which accurately recapitulates the disease's cell mix and behavior. The organotypic slice culture model offers promising new avenues for studying the pathobiology of this rare tumor and testing potential treatments.
Researchers found that reducing SAMHD1 levels made brain tumor cells sensitive to chemotherapy drugs and slowed cell growth. They also suspect that glioblastoma alters SAMHD1's function to aid its own survival and treatment resistance.
A new technique combines holographic microscopy with deep learning to follow individual microscopic organisms in the ocean. The method allows for continuous measurement and quantification of micro-zooplankton and feeding events, revealing key interactions between species.
Researchers developed an algorithm to extract bouton-like structures from calcium imaging data, identifying synchronized synapses during fictive locomotion. PQ-clustering outperformed other algorithms in mimicking synaptic activity patterns.
A recent study shows that a third of American women now face excessive travel times to obtain an abortion, with residents in the South facing the biggest jump. The share of women traveling over an hour for care has doubled, exceeding the US government benchmark for reasonable access to primary care. Black and indigenous women are dispr...
Dr. Volpp's research on behavioral economics and health incentives has significantly advanced understanding of cardiovascular outcomes, leading to changes in benefit design and program offerings. He is also the founder of Penn Center for Health Incentives and Behavioral Economics.
A majority of gig economy workers report feeling threatened by online reviews, which can negatively impact their earnings. The study found that algorithms used to rank workers are opaque and volatile, leaving workers vulnerable to malicious customers. This 'reputational insecurity' is creating instability in the workforce, with some wo...
A new study by University of Maryland School of Medicine researchers found that girls aged 13 or younger who get pregnant have significantly higher risks of preterm birth, cesarean delivery, and ICU admission compared to older pregnant teens. These young girls experience increased health complications due to their age.
CU Anschutz researchers found changes in myelination during learning, altering neuronal communication speed. These changes could lead to better treatment for neurological injuries and disorders like multiple sclerosis.
A large study of over 5,800 tween children found that growing up in a socioeconomically disadvantaged household can have lasting effects on brain development, with different patterns of connections between brain regions observed. Parental education emerged as the most significant factor associated with variations in brain connections.
Researchers at POSTECH developed a stable aqueous zinc-ion battery that uses water as an electrolyte, reducing the risk of fires and explosions. The new battery features a protective polymer layer to prevent electrode corrosion and increase stability.
Researchers at Göttingen University have found fluorescent color patterns in fossils from the Triassic period, making them the oldest of their kind. The study reveals a surprising variety of stripes, zigzags, and flame patterns, similar to those of modern seashells.
Researchers found coastal embayments experience episodic hypoxic events and increased hypoxic conditions compared to open coastline. These areas are likely to be impacted by climate change and ecosystem changes.
Weight loss and increasing blood glucose levels are early indicators of pancreatic cancer, potentially leading to a more timely diagnosis. Researchers analyzed data from 8,777 patients diagnosed with pancreatic cancer and found that these symptoms could be detected two years before an official diagnosis.
Researchers at CU Anschutz Medical Campus found that administering midazolam increases the risk of myocardial injury in non-cardiac surgery performed at night. The timing of drug administration can affect its efficacy and increase the risk of heart damage, suggesting a need to reevaluate treatment strategies.
Research published in Journal of Neurology Neurosurgery & Psychiatry found that obesity at MS diagnosis is associated with higher current and subsequent levels of disability. Reverting to a healthy weight may improve clinical outcomes for obese patients with MS, suggesting a modifiable risk factor.
Zebrafish studies reveal a key role of gut microbes in shaping brain circuits responsible for social behavior. The findings suggest a possible translation to mice and humans, offering new insights into neurodevelopmental disorders such as autism spectrum disorder.
Dr. Ralph L. Sacco, a top stroke neurologist, has advanced understanding of cardiovascular and cerebrovascular diseases through his research on race-related stroke risk. He is recognized for his work in creating targeted stroke prevention programs.
Scientists have discovered exceptionally well-preserved fossils in China that date back 514 million years, revealing the first animals to build hard and robust skeletons. The fossils show features characteristic of modern jellyfish and cnidarians, including a tubular structure made of calcium phosphate.
A new study from the University of Vermont found that TikTok's most viewed content on food, nutrition, and weight promotes a toxic diet culture, with weight loss and thinness glorified. The study highlights the need for critical thinking skills and a radical rethinking of how we relate to our bodies, food, and health.
Researchers at the Lieber Institute for Brain Development have found that neuronal cells are unable to precisely control levels of dopamine, leading to a genetic mechanism that controls dopamine flow. This study confirms that dopamine is a causative factor in schizophrenia, shedding light on a long-held hypothesis.
Researchers at UNH tested state-of-the-art calculations of the strong force with an experiment probing proton spin, finding agreement with one but not the other. The findings provide a benchmark for testing the strong force and its applications in future technology.
Researchers discovered a new daily rhythm in inhibitory synapses, which rebalance brain activity to consolidate new information into long-lasting memories during sleep. The study suggests that wakefulness strengthens inhibitory synapses, enhancing memory formation.
The study reveals that the small intestinal microbiome is unstable and changes in response to diet, but certain species persist and adapt through subspecies changes. The findings have important implications for understanding intestinal diseases such as celiac disease and Crohn's disease.
The Alpha Stem Cell Clinic will develop preclinical studies into early and later phase clinical trials with the goal of establishing advanced regenerative medicine treatments. The clinic will also foster greater collaboration with eight similar clinics across the state and educate the public about stem cell and related therapies.
The 2021 Texas law banning abortion in early pregnancy led to a significant decrease in facility-based abortions within Texas and an increase in out-of-state abortions among residents. Over the 6-month period following SB 8 implementation, the percentage of out-of-state abortions at 12 weeks or more gestation rose substantially
A new book by Aston University financial regulation expert Dr Daniel Cash proposes a temporary change to the way credit ratings are decided to help poorer countries avoid downgraded ratings and borrow money for vital improvements like healthcare and infrastructure.
KAUST researchers have designed a smart glass system that can encode data into the light passing through it, allowing for wireless data transmission. The system uses polarization manipulation to eliminate flicker problems and can transmit data at rates of up to 16 Kilobits per second.
Researchers mapped the detailed neural pathway of defensive responses from the gut to the brain in mice after detecting germs. The study could lead to better anti-nausea medications for cancer patients undergoing chemotherapy.
A novel cloud-based framework is proposed to manage and analyze industrial IoT data in cloud environments, optimizing energy consumption through reinforcement learning. The system aims to provide an energy-efficient and secure environment for industries such as healthcare and education.
The US Department of Energy's Oak Ridge National Laboratory has developed a massive geographic dataset, USA Structures, using deep learning to forecast potential damage and accelerate emergency response. The dataset provides critical information on building outlines and attributes, enabling FEMA to prioritize response efforts.
Lehigh University researchers have developed a new fabrication method for high-entropy alloys that can operate in extreme temperatures. The process uses lower temperatures and a different reaction route to achieve a more homogenous microstructure, potentially leading to the development of more efficient materials for aerospace and indu...
A cross-sectional study found that excessive alcohol use was responsible for an estimated 1 in 8 total deaths among US adults ages 20-64. Increasing evidence-based alcohol policies, such as higher taxes and regulation of outlet density, could significantly reduce premature deaths.
A study reveals that interleukin 34 (IL-34) modulates the balance between two myeloid-derived suppressor cell populations, leading to immunosuppression and chemoresistance in triple-negative breast cancer. Neutralizing IL-34 with a drug reduces tumor growth and susceptibility to chemotherapy.
Researchers found no fatalities or significant injuries from VNR use, with a 92.6% success rate in taking combative individuals into custody. The study suggests that banning VNR may limit law enforcement's options, and that the technique is a safer alternative.
A new funding grant will be used to investigate the effectiveness of 'Fastball EEG' in detecting three major types of dementia, including frontotemporal dementia and Vascular Dementia. The technology has shown high accuracy in picking up small changes in brain waves associated with memory recall.
A new study from Harvard T.H. Chan School of Public Health found that higher exposure to political conservatism is associated with higher COVID-19 mortality rates and increased stress on hospital intensive care unit (ICU) capacity. The study examined data from all 435 U.S. Congressional districts between April 2021 and March 2022.
Scientists have discovered that leukemia cells can change their DNA read-out to evade treatment, making them harder to treat. The study identified key genetic changes that allow cancer cells to survive and relapse.
The study found that protein kinase CK2 plays a key role in regulating CD8+ T cell activation, metabolic reprogramming and differentiation during infection by the intracellular pathogen Listeria monocytogenes. In mouse models, deletion of the CK2α catalytic subunit impaired CD8+ T cell function.
Researchers discovered a link between reduced protein synthesis and Feingold syndrome type 1, a rare genetic disorder. The study suggests that a nutritional supplement may help reverse this decrease, potentially alleviating intestinal symptoms in patients with the condition.
A new study found that bats play a crucial role in protecting young tree seedlings from insect damage, with three times fewer bugs and five times more defoliation when bats are absent. The research reveals a mutually beneficial relationship between bats and oak trees, with bats serving as a key predator for insects that harm the trees.
Dr. Susan E. Quaggin, a leading expert in kidney health, has been recognized as one of seven Distinguished Scientists by the American Heart Association. Her groundbreaking research on transcription factor action and vascular endothelial growth factor has led to new insights into pre-eclampsia and kidney disease.
Germ-free zebrafish larvae have altered neural connections due to reduced microglia pruning by immune cells. Reintroducing normal microbiota restores normal development and social behavior. Microorganisms stimulate microglial activity, promoting neural connection remodeling.
Dr. David Kass, a Johns Hopkins professor, has advanced understanding of heart disease and its treatments through pioneering clinical studies and molecular research. His work has led to the development of new therapies for heart failure, obesity, muscular dystrophy, and potentially immunotherapy for cancer.
A CSU study found that racially segregated communities are exposed to a more concentrated form of air pollution, including toxic metals like lead and cadmium. This disparity is linked to systemic racial injustices and targeted emissions reductions can help reduce exposure.
A study analyzing historic habitat mapping data in Hamburg found a decline of species-rich habitats due to urbanization, while also revealing the colonization efforts of certain plant species. The research highlights the potential of these datasets for biodiversity research, with trends observed across Germany and Europe.
Researchers found that protein disulfide isomerase (PDI) regulates radio sensitivity through mitophagy, promoting tumor growth and metastasis. PDI inhibits mitophagy signaling by blocking the interaction of LC3II-PHB2, leading to increased mTOR pathway activation.
Researchers have identified changes in chromatin accessibility that occur in aging muscle stem cells, which may be reversible. By understanding these changes, scientists can develop new approaches to prevent or reverse cellular aging.
A Dartmouth study reveals that disruptions in the mTORC1 pathway can rescue neuronal overgrowth and synapse function dysregulated by Pten loss, potentially offering new treatments for autism spectrum disorders. The research team also found that administering Rapamycin to children showed some benefit to symptoms of autism.
Researchers can now study microplankton at an individual level using holographic microscopy and AI, gaining a deeper understanding of their movement, growth, reproduction, and interactions. This breakthrough provides new insights into the ocean's oxygen production and carbon cycle.
A team led by Douglas Jerolmack and Paulo Arratia used laboratory experiments to understand how mudslide failure and flow behavior relates to soil material properties. They found a clear signal in 'dirty' samples using high-tech rheometers, shedding light on the tipping point for slope liquefaction.