A new approach uses reinforcement learning algorithm to help robotic knee mimic intact human knee in walking, achieving 100% success rate on even ground. The technology also adapts to uneven terrain and changes in walking pace, promising a more comfortable experience for prosthetic users.
Researchers at UMass Lowell are developing a production method to freeze-dry COVID-19 vaccines activated by messenger-RNA, eliminating the need for refrigeration. The innovation could ease supply chain issues and deliver lifesaving immunizations to more people worldwide.
Researchers identified a single type of neuron responsible for coordinating leg movement in the spinal cord, which was found to be necessary and sufficient for locomotor behavior. The findings have important implications for developing new treatments for people with spinal cord injuries or motor disorders.
Researchers found that the oral plug, a structure in fin whales, blocks the pharynx and prevents water from entering during lunge feeding. This allows the whale to swallow prey while keeping the respiratory tract protected.
The HNRCA will collect data from a cohort of 2,000 people to develop algorithms predicting individual responses to diet and nutrition. The goal is to create personalized nutrition recommendations based on factors like genetics, metabolism, and environment.
Research reveals that magmas from Mount Etna and Mount Vulture have extremely high Nb/Ta ratios, indicating a deep carbon-rich lithospheric mantle beneath southern Italy. This process contributes significantly to global volcanic CO2 emissions.
Researchers from the Croatian Centre of Excellence for Advanced Materials and Sensors present five new or modified circuits intended for building a universal computer based on the Random Pulse Computing (RPC) paradigm. The development marks an advancement in the theory of impulse circuits.
Melanoma cells release small packages containing the protein NGFR, which primes nearby lymph nodes to form new vessels and encourage cancer spread. This process, called lymphangiogenesis, may help doctors determine which patients need more aggressive treatment.
A new study published in the Journal of the American Medical Association finds that those who received the Moderna COVID-19 mRNA vaccine have a lower risk of experiencing 'breakthrough' COVID-19 cases compared to recipients of the Pfizer-BioNTech mRNA vaccine. The study also found that Moderna recipients were less likely to be hospital...
UAB surgeons successfully transplanted a genetically modified pig kidney into a brain-dead human recipient, testing safety and feasibility in a novel human preclinical model. The experiment showed that the xenograft perfused normally and maintained vascular integrity, paving the way for potential treatment of thousands with organ failu...
The Microbiome and Metagenomics Center at UC San Diego will analyze stool samples from 10,000 All of Us Research Program participants to develop algorithms predicting individual responses to food. This will enable personalized nutrition recommendations based on an individual's genetics, gut microbes, and lifestyle factors.
The center will leverage AI, machine learning, and Big Data methods to understand individual dietary needs and avoid biases. This collaboration between CUNY SPH and West Point aims to improve health equity and advance precision nutrition.
A study by Massachusetts General Hospital found that female physicians ask and answer fewer questions than their male counterparts in large classes, using more deferential language. This may lead to gender biases in grading, disproportionately disadvantaging women.
Researchers discovered that lunge-feeding whales have an 'oral plug' in their mouths, which seals off the upper airways during feeding. This mechanism prevents water from entering their lungs and allows them to gulp down large amounts of krill without drowning.
The study reveals that Omicron's spike protein mutations increase its binding affinity to human cells and evade antibodies, contributing to its increased transmissibility. The researchers aim to develop more effective treatments against Omicron and related variants using this knowledge.
Researchers at ETH Zurich analyzed garnet crystals from volcanic deposits to infer magma chamber residence times. They found that phonolitic magma stored in the upper crust for several thousand years before triggering an eruption, and a reservoir of this magma has existed beneath Vesuvius for the last 10'000 years.
Research found that even mild head injuries can lead to a 35% reduction in primary visual cortex neurons and decreased neuronal activity, resulting in persistent visual impairment. The study used adult mice and showed that TBI affects inhibitory neurons more than excitatory ones.
Researchers at INRIM demonstrate a novel method for enhancing long-distance quantum key distribution by leveraging coherent laser interferometry, single-photon technologies, and quantum metrology. This breakthrough enables lower error rates and increased message length, paving the way for more efficient QKD protocols.
Scientists have identified a new tool to control the movement of motor proteins in neurons, which could lead to new treatments for cancer and neurodegenerative diseases. The study found that the GSK3β enzyme can act as a stop switch for kinesin 1 motors, preventing them from detaching from microtubule tracks.
Researchers have identified several factors that can predict the development of long COVID, including the presence of certain autoantibodies, pre-existing Type 2 diabetes, and low cortisol levels. The study found that administering antivirals early in the disease course may also prevent some long COVID symptoms.
A recent study found that 84% of adults with asthma experience discomfort while wearing a mask, and 75% report trouble breathing or shortness of breath. The study also discovered an association between poorer asthma control and higher symptoms while wearing a mask.
Researchers have designed and built bioreactors at a fraction of the cost of commercial systems to investigate bacterial biofuel production. A subtle change to a single gene can result in remarkable changes to how sugars are converted to biofuel products, revealing new avenues for improving biofuel production.
A UCLA-led meta-analysis of individual patient data from three cohorts found that patients receiving high-dose external beam radiation therapy alone may benefit from longer androgen deprivation therapy (ADT) durations, while those with external beam radiation therapy and brachytherapy boost may be optimally managed with shorter ADT. Th...
Researchers at the University of Delaware have developed a low-pressure method to convert industrially processed biomass into high-performance plastics and valuable chemicals. The process uses glycerin as a solvent instead of methanol, reducing costs and environmental impact.
A team of Weill Cornell Medicine investigators created a comprehensive atlas, called Tau interactome, that maps all the Tau protein's interactions with other proteins in human neurons. They found that mutations diminish Tau-mitochondrial protein interaction may hamper energy production and lead to cognitive decline.
A new federally funded study will use machine learning to create a first-of-its-kind algorithm predicting individual responses to food and dietary routines. The National Institutes of Health's All of Us Research Program will recruit 10,000 participants nationwide.
A systematic review of 43,000 participants found cannabis use leads to acute cognitive impairments that persist beyond intoxication. Cannabis intoxication impairs areas including concentration and memory, with potential consequences for daily life, education, and work performance.
Researchers have developed a new nanocatalyst for the dry reforming of methane, overcoming coking resistance with its confined core-shell structure. The catalyst's superior carbon resistance is attributed to the confinement and electron transfer between In and Ni.
A new study found that nearly four times as many words describing rough surfaces contain the trilled /r/ sound compared to smooth ones. This pattern is prevalent across sensory words in 38 Indo-European languages and has likely existed for over six millennia.
Researchers at UAB successfully transplanted genetically modified pig kidneys into a brain-dead human, demonstrating the feasibility of xenotransplantation. The kidneys functioned for 77 hours without immediate rejection, paving the way for potential treatment of thousands suffering from kidney failure.
A team of researchers from Charité – Universitätsmedizin Berlin has identified a neural network that generates tics, which could lead to improved treatment of people with Tourette syndrome. The study found that targeting this network via deep brain stimulation can alleviate symptoms in patients.
A study found that lung cancer screening among non-smoking women in Taiwan has led to a 6-fold increase in early-stage diagnoses, while late-stage cancer and death rates remain stable. The researchers estimate that between 7,000 and 12,000 Taiwanese women have been overdiagnosed with lung cancer.
Researchers used electronic health record data from over 700 hospitals to train and evaluate three machine learning algorithms, finding that XGBoost provided the highest accuracy in predicting CDI among hospitalized patients. The study suggests that MLAs can help reduce the clinical and economic impact of healthcare-associated infections.
Researchers developed an autonomous assembly method for a 3-arm robot to fix a multi-pin and hole load plate on a space station. This solution tackles the challenges of complex environmental lighting and matching multiple groups of holes and pins in the task. The study reduces astronaut safety risks by leveraging robots instead of humans.
Scientists have compared electron distribution in two semiconductors to develop stable topological quantum bits for quantum computing. Indium antimonide shows a low electron density below its oxide layer, which is advantageous for forming Majorana fermions and creating compact, efficient quantum computers.
Acute COVID-19 infection can lead to various neurological symptoms, including confusion, stroke, and depression, which persist months after infection. The authors propose possible mechanisms, such as vascular and immune dysfunction, that may give rise to these symptoms and trigger future neurodegenerative diseases.
A study published in Science Advances found that cannabidiol (CBD) inhibited SARS-CoV-2 infection in human cells and mice, suggesting its potential as a preventative or early treatment for COVID-19. CBD's effects were confined to high purity doses and specific situations.
Researchers discovered that Rubisco's activity drops more rapidly in cowpea leaves when they go into the shade, resulting in missed opportunities to convert sunlight into sugars. This imperfection could be shared with other crops and may lead to targeted breeding for improved productivity.
A study by Professor Kazumichi Matsumiya from Tohoku University's Graduate School of Information Sciences has discovered separate body maps for different motor systems. This finding can contribute to the development of new diagnostic techniques and rehabilitation strategies for patients with motor dysfunctions.
A new ultra-fast cell sorter uses fluorescence imaging to enable genome-scale studies of complex phenotypes, expanding the accessible phenotypic space for cell sorting applications. This technique can rapidly isolate and quantify cells with diverse phenotypes, including those with differently localized proteins or in different mitotic ...
A study found that car owners place a higher value on green spaces in shared courtyards, with a twofold increase in attention to trees making the area 30% more attractive. This internal conflict highlights the need for architects and developers to prioritize green spaces in construction planning.
A new study warns that 'fidelity' in educational trials may be compromising the effectiveness of promising innovations, leading to unnecessary scrapping. The researchers ran a large-scale simulation of over 11,000 trials to examine the impact of fidelity on results.
A new study of Chinese older adults found that higher levels of social isolation are associated with having fewer teeth and losing teeth more quickly over time. Despite this, loneliness was not linked to the number of remaining teeth or tooth loss rate.
Researchers found that young children and infants infer closeness in relationships through activities like saliva sharing. Saliva sharing is a cue for relationship thickness across cultures, suggesting an early understanding of social structures.
The study finds that pentatellurides exhibit nonlinear transport behavior when subjected to magnetic fields, leading to the emergence of many-body effects in Dirac electrons. This phenomenon is characterized by a 3D density wave state that can be suppressed or activated by electric field thresholds.
A clinical trial found that peanut oral immunotherapy desensitized most highly allergic children and induced remission in one-fifth. Younger children and those with lower levels of peanut-specific antibodies were more likely to achieve remission, with 71% of 1-year-olds experiencing remission.
The new BD CellView Image Technology enables high-speed sorting of individual cells based on detailed microscopic analysis, accelerating discovery research in immunology, cell biology, and genomics. This technology has the potential to unlock new cell-based therapeutic discoveries and transform various fields of biomedical research.
A recent study found a strong association between aerobic power training and high-intensity performance in elite soccer players, except for centre backs. Researchers used targeted treadmill training and lactate blood samples to assess aerobic fitness, revealing individual differences in physiological performance.
A new study by Universidad Carlos III de Madrid researchers has detected a significant digital gap in internet usage between rich and poor people, with poorer areas consuming more social media and traditional news outlets. The study found that higher levels of education and purchasing power are associated with more traditional online m...
Researchers found that pig cells undergo apoptosis at a higher rate than human cells in response to SARS-CoV-2 infection, helping to limit viral replication and avoid severe illness. This discovery could lead to therapies designed to trigger apoptosis in human cells, reducing the severity of COVID-19 symptoms.
In a study published in Cell, researchers report that ventral spinocerebellar tract neurons (VSCTs) are both necessary and sufficient for regulating locomotor behavior in mice. Activation of VSCTs induces locomotion, while suppression halts it, demonstrating their crucial role in controlling this essential behavior.
A study found that recreational cannabis companies market their products in a way that appeals to children and teens, despite state-based regulations prohibiting it. The marketing is easily viewed by people of all ages on social media platforms.
The global chemical industry aims to recover from the pandemic while addressing consumer demand for sustainable products. Investments in carbon capture and clean technology will continue to rise, while companies rethink packaging and manufacturing methods to reduce waste.
Researchers found that small groups of scientists are key in generating emerging topics in life sciences and medicine. The study analyzed PubMed data and author lists to identify past and current emerging keywords, revealing that smaller teams with fewer publications were crucial for generating high-performance keywords.
Cidon's new software framework, XRP, aims to speed up cloud computing by offloading storage functions to the operating system. The project expects to more than halve computation and energy needed for common storage operations on fast storage devices.
The NIH is awarding $170 million to clinics and centers for a precision nutrition study that will develop algorithms to predict individual responses to food and dietary routines. The Nutrition for Precision Health study will recruit 10,000 participants from the All of Us Research Program.
A study published in Diabetes Care found that walking regularly at greater intensity and taking more steps can lower the risk of developing Type 2 diabetes among adults aged 65 and older. For every 1,000 additional steps per day, the risk is reduced by 6%, with a 12% reduction possible if an average adult takes 2,000 more steps daily.
The article shares actionable steps to position nurses as leaders in innovation, highlighting Penn Nursing's successful infusion of innovation into its mission and curriculum. Key findings include the importance of developing a shared meaning of innovation within the university and healthcare community.
A new study by Boston University School of Public Health investigators finds that COVID-19 vaccination in either partner does not impair fertility. In contrast, males who test positive for COVID within 60 days of a cycle have reduced fertility compared to uninfected men.
A 20-year study found that older adults who adhered to the Mediterranean diet had a lower risk of mortality. The study used dietary biomarkers to assess adherence and found an inverse association with all causes of death.
A UOC study found that 62% of Barcelona residents are favourable to tourism, with two profiles emerging: 'tourism supporters' and 'residents who support tourism'. The study highlights the importance of understanding the emotional responses to mass tourism in urban environments.
A study analyzed Medicare claims data to compare health outcomes of patients admitted on busy versus less busy hospital days. The results showed that hospitalists' treatment decisions have a significant impact on patient outcomes, with better care provided on less busy days.
A study by Mayo Clinic researchers found that cancer patients receiving chemotherapy and targeted therapies may mount inadequate immune responses to COVID-19 vaccination. The authors recommend antibody level testing and booster vaccinations for these patients.
The NUS research team achieved a power conversion efficiency of 23.6% in their perovskite/organic tandem solar cells, approaching that of conventional silicon solar cells. This breakthrough paves the way for flexible, light-weight, and low-cost photovoltaic cells suitable for various applications.
NAU's Cristina Thomas is a renowned planetary astronomer who has received numerous awards for her groundbreaking research on asteroids and planetary defense. She is also recognized for her exceptional teaching and mentorship, making her a role model for underrepresented communities in STEM fields.
Young children and babies use saliva sharing as a cue to determine strong relationships and mutual obligations. Research found that babies expect people who share saliva to offer help when distressed, suggesting a vital skill for learning social relationships.
Native marine macroalgae thrive in environments created by natural groundwater seeps, benefiting from enhanced nutrients despite lowered salinity levels. In contrast, tainted groundwater seeps support invasive species, threatening native algal dominance.
Researchers report COVID-19 can cause a range of neurological symptoms, including loss of taste and smell, headaches, and brain inflammation. A new study suggests Long Covid may share common risk factors with myalgic encephalomyelitis/chronic fatigue syndrome.
Researchers developed reference materials with known viral loads to standardize PCR test results. The study found that Ct values varied among labs, highlighting the need for reference materials to compare and standardize results.
A randomised controlled trial found that most young children treated with peanut immunotherapy achieved desensitisation after two and a half years of treatment, while one in five remained in remission. Younger children under one year old were more likely to achieve remission, suggesting early interventions may provide better outcomes.
A survey study of 2,100 participants found that LGBQA+ individuals were at higher risk of experiencing sexual violence during adolescence and young adulthood. The study highlights the need for increased support and protection for this vulnerable population.
The study found that elevated CO2 concentration increases CH4 emissions by 23%, but reduces N2O emissions by 22%. However, with longer duration of CO2, emissions decrease by 27% and 53%. Appropriate agricultural management practices, such as straw incorporation and water regimes, also affect these emissions.
Scientists at University of Texas M. D. Anderson Cancer Center and Northwestern Medicine identified naturally occurring vesicles containing ACE2 protein in patients' blood that can prevent or treat SARS-CoV-2 infection. These evACE2 act as decoys to lure the virus away from cells, preventing infection.
Researchers argue that understanding human evolutionary roots of privacy is crucial to securing its future in the digital age. Historical and anthropological research shows that humans' need for privacy has remained constant throughout history.
A study found that preventing mental health problems among schoolchildren, particularly externalizing disorders, could have prevented grade repetition and dropout. The study involved 2,511 families with children aged 6-14 and showed that girls with externalizing disorders were more likely to be held back a grade.
Scientists have identified natural nano-bubbles containing the ACE2 protein in COVID-19 patients' blood, which can block infection from broad strains of SARS-CoV-2 virus. These nano bubbles serve as a decoy to lure the virus away from cells, preventing infection.
A study by researchers at NYU School of Global Public Health and Tufts University found that only a third of online grocery items display required nutrition information. This omission poses significant health risks for consumers, particularly those with allergies or dietary restrictions. The authors advocate for federal regulation to e...
Researchers developed a machine learning approach enabling robots to separate, recognize, and grasp individual objects with high accuracy. The method achieved 97% success rate in real-world experiments, paving the way for industrial parts sorting and residential waste sorting applications.
A new study confirms the accuracy of the European Association of Urology (EAU) risk classification system for prostate cancer patients, using PSMA PET imaging to identify subgroups with varying disease risks. High-risk groups showed higher metastatic disease rates, while low-risk groups had undetectable or distant metastases.
The WV Clinical and Translational Science Institute is leading a national study on post-acute sequelae of COVID-19 (PASC) among adults. The study, funded by the National Institutes of Health, aims to better understand the long-term effects of COVID-19 and develop effective treatments for this disabling complication.
Scientists have mapped the tau interactome, showing that mutant tau impacts mitochondria function in human neurons. The study also reveals a mechanism for tau release from neurons and its binding to mitochondrial proteins, which may inform future studies on preventing diseased tau spread.
Researchers developed a host-guest MOF platform for rational construction of D-A materials and achieved TADF with controlled PLQY and PL intensity. Spatial alignment of donor and acceptor molecules enhances radiative transition processes.
Sophie Paczesny's research aims to validate biomarker panels that help doctors predict chronic GVHD risk and adjust immune suppression treatments accordingly. The study uses machine learning algorithms to analyze stored plasma and blood cell samples from over 1,300 BMT recipients.
Researchers conducted a free-flight ballistic range test to capture the attitude behaviors and aerodynamic characteristics of Tianwen-1 Mars entry capsule. The study revealed that the capsule is dynamically unstable in pitch and yaw directions, but statically stable in these directions.
Samantha Kleinberg's project will analyze data from diverse populations to find causal relationships between diets and specific health outcomes. The goal is to tailor diets to individual characteristics and circumstances for better health outcomes.
Researchers confirm a rare and massive black hole merger with an eccentric orbit, shedding light on the formation of supermassive black holes in dense star clusters. The study's findings have significant implications for our understanding of black hole dynamics and the evolution of galaxies.
A prospective observational study found that preoperative shear wave elastography (SWE) can predict successful rotator cuff repair. SWE-derived elasticity was higher in patients with insufficient repair, and the elasticity ratio independently predicted insufficient repair.
Researchers discovered that old neurons can block neurogenesis in mice, highlighting excessive senescence as a driving factor behind aging. By destroying senescent cells, the study showed enhanced hippocampal neurogenesis and cognitive function in middle-aged mice.
A new study published in Cell Reports Medicine found that a cancer drug called ADI-PEG 20 improved insulin sensitivity, cholesterol levels, and reduced inflammation in mice. The treatment also caused significant weight loss in obese mice, suggesting potential benefits for human obesity treatment.
A study published in Alzheimer's & Dementia: The Journal of the Alzheimer's Association found that 12 to 14 intervention sessions can improve cognition in older adults at risk of dementia. The optimal dose was determined by analyzing data from the Multidomain Alzheimer Preventive Trial, taking into account individual characteristics su...
A new study reveals that GMO labeling significantly affects consumer behavior, reducing demand for GM foods and influencing willingness to pay. The research finds that mandatory presence-focused labeling has a stronger impact than voluntary absence labeling, making consumers more sensitive to the GMO attribute and price information.
A new method of molecular-level control, called induced activation, doubles the efficiency of widely used industrial catalysts. This approach manipulates the catalyst surface by controlling reducing agents at the catalyst activation stage.
Researchers at TTUHSC developed novel hydrophilic nanoparticles that target bacterial membranes, killing pathogens while sparing mammalian cells. The nanoantibiotics' size-dependent activity reveals a new blueprint for developing non-toxic and environmentally friendly antibiotics.
Researchers at MIT have developed an all-in-one approach to diabetes treatment, streamlining the process of blood glucose measurement and insulin injection. The new device can automate procedures such as pricking skin, collecting blood, calculating glucose levels, and dispensing insulin, reducing the need for multiple devices and makin...
Researchers have successfully synthesized a new 2D material, 2D cuprous iodide, by stabilizing it in a graphene sandwich. The study's lead author notes that understanding the structure was crucial to designing a chemical process for large-scale production.
The eLTER call offers Transnational Access (TA) and Remote Access (RA) for scientists working on biodiversity, biogeochemistry, and socio-ecological research. The 39 sites in 19 countries provide state-of-the-art instrumentation and long-term data.
A new study published in Mammalian Biology analyzed the life history data of 13 North Atlantic right whales using genetic samples and photo identification. The researchers found that four calves previously thought to be dead survived, revealing a significant variation in calf separation time from mothers and physical development.
A new open-source tool called SwolfPy helps solid waste systems achieve environmental goals by assessing various options in one place. The tool identifies the range of best possible options for users, depending on their priorities.
Researchers replaced traditional electron-transport layers with quantum dot layers in perovskite solar cells, resulting in record power-conversion efficiencies of up to 25.7%. The use of quantum dots also enabled high operational stability and scalability, making them a promising solution for large-scale solar energy production.
Scientists have built a three-dimensional model of a living minimal cell, which mirrors its behavior and allows for the prediction of how it functions. The model reveals key insights into how cells balance their metabolism, genetic processes, and growth.
A new study by Yale researchers found that the Sinovac vaccine, widely used in 48 countries, offers little protection against the Omicron variant. Booster shots are necessary to combat the dominant circulating virus, which has shown to produce no neutralizing antibodies among those who received two doses of the Sinovac vaccine.
Researchers from National Institute for Environmental Studies identified that radiocesium accumulates primarily in organic soil layers and stagnant water, contaminating organisms. Fertilizing contaminated areas with potassium can suppress biological absorption of radiocesium.
A team of scientists from Germany, Spain, Australia and Japan discovered a new species of branching marine worm, Ramisyllis kingghidorahi, in Japan. The worm has a unique body shape with one head and multiple posterior ends, living inside the internal canals of sea sponges.
Researchers have created PicoShells, microscopic particles that can speed up the growth and analysis of microorganisms, including algae. This new tool enables faster identification of cell strains suitable for mass production, potentially shortening R&D timelines by months.
Researchers found that people who were in a sad mood improved more quickly when they used a mood-improving method that they were told was their strongest skill. This approach helped participants regain confidence and persistence, leading to better results.
Researchers at NIMS and Softbank Corp. have created a lithium-air battery with an energy density of over 500 Wh/kg, significantly higher than existing lithium-ion batteries. The new battery can be charged and discharged at room temperature, showcasing the highest energy densities and best cycle life performances achieved.
MIT researchers develop teaching phase that guides humans in understanding AI strengths and weaknesses, enabling more accurate decisions and faster conclusions. The technique helps humans build a mental model of the AI agent, reducing reliance on biased assumptions.
By shaking an optical lattice potential, researchers realized a discontinuous phase transition in a strongly correlated quantum gas, opening the door to quantum simulations of false vacuum decay in the early universe. This work provides a flexible platform for exploring the role of quantum fluctuations in first-order phase transitions.
Scientists at Osaka University have successfully manipulated nanoparticles suspended in superfluid helium using optical tweezers, opening the way for new cryogenic applications and potential visualization or control of vortices. The research may help better understand interactions between quantum fluids and classical nanomaterials.
A study found that a daily supplement of urolithin A improved muscle function and reduced inflammation in older adults. The supplement, produced by gut bacteria, was shown to stimulate mitophagy, a process that recycles damaged mitochondria.
A worldwide network of optical magnetometers failed to detect dark matter signals over a one-month continuous operation. The researchers were able to formulate constraints on the characteristics of dark matter using the data from nine stations in six countries.
Researchers have identified nine new factors involved in DNA repair, a critical process for human cell health. The findings can help develop new cancer drugs and improve existing therapies.