A single genetic test using RNA sequencing has been used for all children with cancer in the Netherlands since 2018, improving diagnosis and treatment in seven cases. The technique picked up 78 fusion genes, 23 of which led to a more accurate diagnosis or possible treatment.
A new study reveals that hibernating ground squirrels' gut microbes play a crucial role in recycling urea to replenish essential amino acids. This process helps the animals survive long periods of inactivity and fasting, suggesting similar mechanisms could be beneficial for humans suffering from muscle wasting and protein malnutrition.
A new Israeli study shows that vaccinated individuals with SARS-CoV-2 infection are less infectious and transmit the virus to household contacts less often. However, the vaccine's effectiveness in preventing transmission waned over time as the Delta variant emerged.
A comprehensive survey of Northeast Asian public attitudes found that hostility towards neighboring countries negatively impacted support for global public goods like climate change mitigation and pandemic management. However, favoring democratic governance models with expert decision-making improved public support.
A new diagnostic tool combines grayscale B-mode and strain elastography ultrasound imaging to detect breast cancer with high accuracy. The model achieved a detection rate of 90% in the study, surpassing individual models trained on either B-mode or SE imaging alone.
A new species of leafhopper, Phlogis kibalensis, has been discovered in the Kibale National Park in western Uganda. The insect belongs to a rare genus that was last recorded in Central African Republic in 1969.
Researchers at Boston University developed a real-time method for projecting COVID-19 quarantine needs in congregate housing settings ten days in advance. The team's findings were published in the American Journal of Public Health and can be used as a predictive tool to allocate resources.
A study by UConn Health and Washington University School of Medicine found that eating more meat correlates with worse MS symptoms, altered gut bacteria, and increased immune cells. The research identified key bacteria and metabolites associated with the disease, providing new insights into its causes.
Researchers aim to determine if knee structure changes predict clinical outcomes in people with osteoarthritis. The study will examine 76,000 X-rays and clinical data from diverse cohorts to establish healthy knee structure ranges.
A study found frequent rates of respiratory infections and wheezing in young First Nations children due to poor housing conditions, including inadequate ventilation, mold, and wood smoke contaminants. The researchers urge action on improving housing and infrastructure in communities to benefit the overall health of First Nations peoples.
Scientists have identified hundreds of proteins constantly transported throughout healthy brain cells, offering a new understanding of neurological diseases like Alzheimer's and autism. The discovery reveals how protein transport goes awry in these conditions, paving the way for future research into intercellular communication.
A recent study found that combining cannabis and alcohol significantly worsens driving performance compared to using either substance alone. This is because the effects of cannabis on driving are additive to those of alcohol, leading to impaired lane control and increased crash risks.
Geosapiens receives major funding from the Canadian Space Agency to develop innovative approaches to flood mapping. The project aims to integrate satellite imagery data for real-time flood zone identification and risk assessment.
Researchers identified genetic characteristics relevant to the production and behavioral attributes of two key bee subspecies, Cape bees and Africanized honey bees. Genetic studies found correlations between dark coloring and cloning behavior in Cape bees, which can take over colonies.
A new report warns that current pathways to net zero climate targets in the UK are flawed and may lead to losses in biodiversity, human wellbeing, and cultural knowledge. The study recommends a more inclusive approach to landscape management, involving experts from diverse fields, to achieve sustainable futures.
A study found that nearly 70% of pediatric patients missed an average of two five-day school weeks post-hospital discharge and half of their primary caregivers missed an average of eight workdays. This highlights the need for interventions to mitigate absenteeism and support families during and after pediatric hospitalization.
A study published in Nature Microbiology reveals that a class of microbial enzymes contributes to ulcerative colitis. Researchers identified an overabundance of proteases from the gut resident Bacteroides vulgatus in nearly 40% of patients, which can exacerbate the disease when not treated with protease inhibitors.
Researchers found that hyaluronic acid is not only present in pancreatic tumors but also serves as a nutrient source for cancer cells. This discovery indicates potential new treatments for pancreatic cancer by targeting the sugar scavenging pathway.
USC researchers will use $18.5 million funding to study colorectal cancer in Hispanic patients, aiming to close the gap in understanding the disease and developing effective treatments. The project aims to improve patient engagement in genomic research and develop culturally relevant educational materials.
A Yale study found that child masking in child care programs reduced closure rates by 13-14%. Child masking was associated with a lower risk of COVID-19-related closures, keeping children in safe learning environments and allowing parents to remain employed. Masking rates were higher for staff members than children.
Boyce's research aims to develop MRI techniques to characterize the interior of flow systems in 3D, leading to revolutionized technologies in sustainable mining and hydrogen-powered vehicles. He plans to use visualizations to inspire middle- and high-school students from Harlem and the Bronx to pursue STEM studies.
Quantum entanglement is studied in attosecond laser laboratory experiments, where neutral hydrogen molecules are ionized using an attosecond pulse. The experiment reveals a competition between vibrational coherence and entanglement, demonstrating the breakdown of local realism.
A new analysis links genetic variants associated with high blood levels of lipoprotein A to a higher risk of prostate cancer, including advanced or early-age-onset cases. The study found no significant associations for other blood lipids.
Scientists have discovered families of proteins that can predict liver transplant rejection, allowing for early detection and modification of immunosuppression. The Blood Proteoform Atlas outlines over 56,000 protein molecules associated with immune cell proteins that change with rejection.
A new study found that the Pfizer vaccine was 91% effective in reducing coronavirus transmission in Israeli households before the emergence of the delta variant. However, with waning immunity, the vaccine's effectiveness decreased to only 40% against infection and transmission.
A recent study led by University at Buffalo researchers found that photobiomodulation reduces inflammation, improves blood flow and heals wounds up to 19 days faster. Light therapy accelerated skin healing from cancer radiation therapy by an average of 49-42 days.
Researchers discovered a genetic mutation associated with small body size in dogs that also occurred in ancient wolves over 50,000 years ago. This finding presents a new evolutionary narrative and challenges the long-held theory that humans domesticated large wolves to create small companions.
A 15-year study in arctic Greenland found that caribou and muskoxen helped mitigate the effects of climate change on rare plants, lichens, and mushrooms. The presence or absence of these large herbivores made a clear difference in species commonness and rarity.
Researchers found that dogs with more extroverted, conscientious, and open personalities tend to rank higher in the hierarchy, while friendlier dogs tend to rank lower. Older dogs also dominate in multi-dog households. The study used a large-scale online questionnaire to analyze the personality traits of over 1,000 dogs.
Researchers have discovered a molecular signaling pathway associated with osteoarthritis (OA) pain, which plays a crucial role in producing and transmitting pain signals. By blocking this pathway, the study shows promise for developing new, effective pain treatments for human OA sufferers.
A new study from Cornell University reveals that fish are more likely to communicate with sound than previously thought. Researchers found 175 families of ray-finned fishes that use sound for communication, including species that have been doing so for at least 155 million years.
A study of 1,000 patients found that some recoverees from hepatitis C still face liver cancer risks after treatment. Researchers propose a 2-step strategy combining FIB-4 and transient elastography/ultrasound to predict high-risk cases.
A global study using thousands of camera trap stations found that protected areas have a positive impact on mammal diversity, even when experiencing human disturbances such as recreational use and logging. The study's findings suggest that expanding protected areas could help conserve larger mammals and their critical roles in ecosystems.
Researchers found that Eurasian reed warblers rely on magnetic inclination as a
Researchers at Cold Spring Harbor Laboratory develop a novel method to modify the CFTR gene, allowing for the production of functional protein in patients with certain mutations. The technique involves using antisense oligonucleotides to skip over the mutation and produce a partially functional protein.
Researchers have developed a nonvolatile approach to modulate interlayer excitons, enabling valleytronics. The method utilizes chemical doping and electrical gating, resulting in retention times exceeding 60 minutes.
Researchers at Hokkaido University have developed a novel catalyst that significantly improves the efficiency of propylene production. The catalyst utilizes carbon dioxide efficiently and exhibits high selectivity, stability, and long-term reusability.
Astronomers at Harvard & Smithsonian Center for Astrophysics offer a new explanation for mysterious downflows in solar flares, which are not generated by magnetic reconnection. Instead, they form from the interaction of two fluids with different densities, resulting in 'dark finger-like voids'.
Researchers have identified a potential novel mechanism of action against drug-resistant tuberculosis (TB) caused by mutations in the EmbR protein, which binds to transmembrane kinase PknH. This study proposes a new approach for computer-aided drug discovery and has important implications for treating other critical diseases.
Researchers at Northwestern University have developed a novel microfluidic device that can efficiently harvest and sort tumor-eating immune cells from tumors. This technology has shown dramatic results in shrinking tumors in mice compared to traditional methods.
Researchers have developed hybrid gelatin-poly-L-lactide scaffolds with tunable hydrophilicity, which structurally mimics the complexity of the extracellular matrix. These scaffolds produced a signal typical of collagen-containing biological fibers when excited by second harmonic generation.
Researchers found that rewarding cognitive effort increases willingness to take on more challenging tasks, even without external reward. This challenges the notion that people inherently want to avoid challenging work, suggesting individual learning histories may play a role in shaping motivation.
A new study in Israel found that vaccinated parents reduce the risk of infection for unvaccinated children by preventing contact with infectious individuals and reducing infectiousness. The study suggests increasing vaccine uptake is crucial to curb pandemic spread and protect vulnerable populations.
A team led by Basmah Riaz has detected deuterated methane in three proto-brown dwarfs, indicating a warmer gas composition than expected. This finding suggests that brown dwarfs may not be simply scaled-down versions of stars.
Researchers suggest airlines adjust VCO presentations based on temporal distance to the flight, providing travellers with options to neutralise their carbon footprint. This can encourage more consumer participation in voluntary carbon offsets, ultimately contributing to a sustainable aviation sector.
A group of plant pathologists have compiled a recovery plan to mitigate tar spot's impact on corn production. The plan reviews current knowledge and future needs, enabling the dissemination of best management practices across state lines.
Researchers analyzed media coverage, laws, and patents to understand the relationship between technology, innovation, and environmental policies. While there has been a shift in public discourse on environmental issues since the 1960s, the impact of technological solutions on the climate crisis is still limited.
A new study analyzes three decades of radar data to build a catalogue of rainbands, helping scientists create storm prediction algorithms. The researchers found that 60% of events resulted in at least one National Weather Service warning, with some associated with atmospheric rivers.
Most of China's seafood imports (74.9%) are processed and reexported, hindering international efforts to preserve global fisheries. The authors argue that a reexport model highlights the complexity of tracing seafood sustainability, and policy reforms are needed for oceans policy reform.
A Brazilian study found that SARS-CoV-2 can persist in patients for over a month before becoming negative on diagnostic tests. Researchers tracked 38 COVID-19 patients and found that the virus remained detectable in three cases for more than 70 days, raising concerns about quarantine periods.
Researchers at the University of Manchester observed the Schwinger effect using graphene-based devices, producing particle-antiparticle pairs from a vacuum. They also discovered an unusual high-energy process where electrons became superluminous, providing an electric current higher than allowed by general rules.
A field experiment in China found that people tend to increase activity when informed that others are themselves increasing activity, suggesting a low-cost intervention for promoting economic activity during the pandemic. The study suggests that social cues can be a useful signal for evaluating risks and making decisions about activities.
A new study proposes a sustainable recycling method for PPE waste using pyrolysis, a medium-temperature reaction that reduces plasticized medical-protection garb into chemicals and petroleum. The method avoids landfill use and incineration, reducing greenhouse gas emissions by 35.42%.
Research found that over 55,000 chemicals in everyday plastic products can reprogram precursor cells to become fat cells, leading to increased fat accumulation. The study suggests that previously unknown plastic chemicals may be contributing to overweight and obesity.
Researchers analyzed data from nearly 500,000 adolescents across 80 nations and found consistent sex differences in career aspirations, with boys dominating 'things-oriented' occupations and girls preferring 'people-oriented' roles. The study also revealed larger differences in gender-equal countries, such as Finland, Norway, or Sweden.
A transparent air filter with a copper nanowire network enables self-sterilization through chemical and thermal disinfection, as well as capture of airborne particles. This innovation addresses the need for antimicrobial filters while preserving visual communication.
Telehealth benefits for family caregivers include increased access to care, continuity of care, and reduced COVID-19 risk. However, concerns arise about caregiver involvement, patient-provider rapport, and quality of chronic condition care.
Researchers at George Washington University have created a blood test that can identify COVID-19 infections and predict their severity. The test detects changes in neutrophil activity and T-cell response, which can help doctors determine the best treatment plan for patients.
A robot performed laparoscopic surgery on a pig without human guidance, demonstrating improved results compared to human surgeons. The Smart Tissue Autonomous Robot (STAR) excelled at intestinal anastomosis, a procedure requiring high precision and accuracy.
Patients under immunosuppressive therapy have increased risk of severe COVID-19 disease courses if they don't respond to primary vaccination. A recent study found that a third booster vaccination is safe and effective in these patients, who were initially unable to produce antibodies after vaccination.