A new ultrasound technique using statistical shape modeling accurately predicts which infants with stable developmental dysplasia of the hip will develop normal hip structure. The method could spare many infants from unnecessary treatment and improve treatment outcomes.
Researchers found that exposure to addiction medicine consult teams led to a significantly reduced risk of death within three months of discharge. Medication played a key role in reducing mortality for patients with opioid use disorders, while other components may be crucial for those with alcohol use disorder.
During the second lockdown, patients and loved ones experienced fewer psychosocial problems, such as anxiety, compared to the first lockdown. Social support from family and friends played an important role in reducing negative feelings like loneliness and sadness.
Researchers at TalTech demonstrate that malicious logic can be inserted into chips while they are being fabricated, compromising sensitive data and secure communication. The team's framework for inserting Trojan Horses causes minimal disturbance to existing circuitry, highlighting the feasibility of this threat.
A new combined 3D modelling technique can accurately predict abnormal heart rhythms in patients with hypertrophic cardiomyopathy approximately 80% of the time. The approach also identifies cardiac diffuse fibrosis as a risk factor for these abnormalities, potentially guiding patient care.
Researchers have identified two new compounds that can inhibit the replication of human herpesviruses by targeting specific enzymes. This breakthrough offers new opportunities for developing agents against herpesviruses, which are currently difficult to treat effectively.
Experts convene to examine how social determinants affect maternal, infant, and lifelong health outcomes. The workshop aims to reduce disparities and inequities in obstetric care.
Researchers are exploring the potential of mycelium-based soil remediation to address lead contamination in urban areas. The team will conduct lab experiments and perform electron microscopy imaging to understand how mycelium cell walls can bind and hold onto lead, as well as precipitate lead minerals around the fibers.
A large multi-year study found that 21.8% of US children have one or more common mental, emotional, and behavioral health conditions. Relational and social risks were associated with a fourfold range in rates of mental health problems among US children.
A team of scientists developed an AI-driven super-resolution technique called Ghost Imaging using Deep neural network Constraint (GIDC) to overcome the diffraction limit in long-distance imaging. GIDC uses single-pixel measurements and a physics-enhanced deep neural network to restore high-quality images.
A new Penn State study found that Black youth with high BMIs reported fewer weight concerns when they had a strong sense of racial identity. Fathers also played a role in shaping their daughters' body image, particularly when involved in teaching about Black culture. The findings suggest that services promoting youth racial identity an...
A new research-practitioner partnership aims to develop a CS/CT curriculum for K-5 settings with a significant Native American student population. The team will design, implement, and evaluate a curriculum that uses Internet measurement as an interdisciplinary approach to understanding computational thinking and computing.
Research reveals that intense storms in the Southern Ocean increase ocean mixing, bringing carbon dioxide-rich waters to the surface and driving an outgassing of CO2 into the atmosphere. This process has significant implications for understanding global climate models and predicting future climate change.
A recent study by Éric Boilard at Université Laval has established a link between the gut microbiota and chronic inflammatory diseases such as arthritis. The research reveals that phospholipase A2-IIA, a protein naturally present in the gut, alters the bacterial lipid profile and promotes inflammation. This finding suggests that local ...
Mariculture has the potential to deliver high-protein foodstuffs with a significantly reduced carbon footprint compared to terrestrial products. The authors suggest various ways to improve mariculture's sustainability, including supply chain improvements and cofarming practices that can lead to net reductions in CO2 emissions.
Researchers at the University of Minnesota Medical School developed a COVID-19 prediction model that performed well across gender, race, and ethnicity for three different outcomes. The logistic regression algorithm created to predict severe COVID-19 facilitated shared decision-making with patients regarding discharge, reducing undue de...
A new paper by Swansea University academics highlights the importance of wellbeing in health, particularly for individuals with chronic conditions. The researchers develop a transdisciplinary framework to improve 'whole health' outcomes, which has been applied to various populations and led to significant benefits.
A new study by Georgia State University reveals that COVID-19 traumatic stress may predict post-traumatic stress disorder (PTSD) symptoms, especially in individuals with a history of past trauma. The findings showed a positive association between COVID-19 traumatic stress and PTSD symptoms across racial groups, except for Asian Americans.
A large population-based study found a significant association between lifetime workplace exposure to pesticides and an increased risk of COPD. The study, which included over 500,000 participants, controlled for other risk factors and found that even low levels of pesticide exposure were linked to a heightened risk of COPD.
The study found a decline in star formation from low-ionization BAL to high-ionization BAL and a rebound of this process from HiBAL to non-BAL. The researchers proposed an evolutionary model to explain the results, suggesting that the outflow caused by AGNs has a global negative feedback on galaxy evolution.
Researchers have developed a protein-based gel that can deliver anti-inflammatory growth factor progranulin to affected joints, halting post-traumatic osteoarthritis (PTOA) onset and progression. The study found that the gel provides prolonged release of progranulin and inhibits chondrocyte catabolism.
The USPSTF recommends against screening for atrial fibrillation in asymptomatic adults aged 50 or older. The current evidence is insufficient to assess the balance of benefits and harms of screening, which is associated with a substantial increase in stroke risk. Atrial fibrillation is a major risk factor for ischemic stroke.
A new framework, known as the Character Lens perspective, has been developed to account for patterns in individuals' understanding of and approach to ethical choices. This framework acknowledges the significant role of moral character in influencing how people perceive the world and make decisions.
Researchers outline a comprehensive framework to tackle early-onset colorectal cancer, addressing epidemiology, molecular landscape, and treatment options. The framework emphasizes the need for tailored support, including peer support, educational counseling, and financial guidance.
Immunosequencing of T cells combined with machine learning techniques reveals that participants with higher numbers of pre-existing memory CD4 T cells develop immunity more quickly and produce more antibodies following vaccination. This study has significant implications for immunity and vaccine development efforts.
Researchers at RIKEN have developed a new retinal transplant technique by engineering human-derived retina sheets to lose bipolar cells, allowing better connections to host retinas and improved responses to light. The technique has shown substantial functional improvement in animal studies and is now poised for human clinical trials.
A new online tool tracks e-bike purchase incentive programs in the US and Canada, providing a point of reference for future policy development. The tracker reveals that most programs set incentive levels fairly arbitrarily, with little thought given to their potential impact on specific groups or income brackets.
A new study reveals that over 85% of primary care practices face difficulties in obtaining evidence-based pediatric behavioral health care, including medication advice and family-based therapy. Policy changes are necessary to address these barriers and ensure comprehensive care for children's growing behavioral health needs.
Researchers detected 43 trillion miniature plastic particles in Switzerland every year, with estimates suggesting up to 3,000 tonnes of nanoplastics covering the country annually. The study reveals that nanoplastics originate primarily from urban areas and global emissions, posing potential health risks when inhaled.
A new study verifies that ancient glaciers caused the erosion of rocks up to 3 miles thick during the Snowball Earth period, resolving a long-standing debate. The research uses thermochronology to estimate temperature and thermal structure, finding a widespread signal of rapid cooling consistent with massive glacier erosion.
A new study published in Fertility & Sterility found that chronic marijuana use negatively impacts male reproductive health, leading to decreased testicular size and lowered testosterone levels. The Oregon Health & Science University study used nonhuman primates to assess the effects of daily THC consumption on reproductive function.
A new study by the University of Auckland found that mothers working from home and experiencing psychological distress were more likely to increase alcohol consumption during lockdown. The research, which analyzed data from over 37,000 adults across 38 countries, suggests that increased psychological distress led to increased alcohol c...
A randomized controlled trial found that late eating, associated with high melatonin levels, impairs blood sugar control through a defect in insulin secretion. Participants with the genetic variant in the MTNR1B gene had higher blood sugar levels, highlighting the importance of considering genetics in food timing recommendations.
A UC researcher is leading three projects to study the genetic workings of deadly pediatric brain tumors, including DIPG. The goal is to understand how genes regulate blood vessels and develop more effective treatments. Researchers are also exploring a new drug that targets a specific genetic mutation.
Researchers found minority groups were less likely to start newer diabetes medications, despite needing them most. The study used data from nearly 5,000 patients with type 2 diabetes and showed Black patients were 20% less likely and American Indian or Alaskan Native patients were 50% less likely to initiate treatment.
Scientists have discovered characteristic breakpoints that alter pollutant concentrations in rivers, impacting global water security. The research sheds light on the behavior of aquatic pollutants in large river systems, including India's River Ganga.
Janus particles, with two distinct physical chemical properties, exhibit unique behavior in simulations. Their shape significantly influences their orientation at interfaces and mobility, impacting rheology and processing schemes.
Scientists at MIT have developed a screening method to study protein-protein interactions, which are crucial in understanding disease mechanisms. The researchers created a synthetic molecule that binds tightly to a protein implicated in cancer metastasis, providing a potential tool for disrupting disease-causing interactions.
Researchers analyzed DNA sequences and electronic health records of thousands of individuals to discover that the chance a pathogenic genetic variant may cause a disease is relatively low, about 7 percent. However, some variants are linked to wide range of risks for disease.
Researchers developed a low-cost and simple method to produce perovskite photovoltaic materials on an industrial scale, paving the way for creating lightweight and flexible solar cells. The new technique reduces waste and toxic byproducts associated with manufacturing perovskite photovoltaics.
A national study by Boston Children's Hospital found that primary care practices caring for children reported significant difficulties in obtaining behavioral health services. The study, published in Annals of Family Medicine, highlights the pressing need for mental health support in children and adolescents.
A new study published in Genome Research has identified a group of genes that play a crucial role in building cellular components and may contribute to human longevity. Inhibiting these genes may increase lifespan by reducing their impact on the body later in life.
This study examined reports of myocarditis after mRNA-based COVID-19 vaccination, finding a higher risk among younger males. The researchers estimated the risk based on age, sex, and vaccine type, providing valuable insights into the potential side effects of these vaccines.
Researchers discovered a protein, syndecan-2, that helps identify and deploy blood stem cells for treatments. Transplanting only cells expressing syndecan-2 could make blood stem cell transplants more efficient and less toxic.
A team of researchers at Rice University has developed a new method to detect tiny cracks in concrete using silicon fluorescence. The technique involves applying a thin coat of opaque paint to the concrete and shining near-infrared light on it, revealing even the smallest microcracks.
A DNA sequencing study of 50 patients with cerebral palsy found a genetic cause in 26% of cases. The study identified 13 different genes associated with the condition. Genetic findings led to changes in patient care plans and urged clinicians to consider genetic causes for CP without known risk factors.
Researchers at Kumamoto University developed a novel 'supermolecular' material that binds to protein drugs, prolongs their effect without impairing activity, and improves overall drug performance. The material, called PEG-PRX, adds polyethylene glycol chains to proteins without compromising biological action.
A novel gene therapy approach using an adeno-associated virus (AAV) has shown promising results in treating Huntington's disease. The therapy targets the mutated huntingtin gene (HTT), providing efficient and precise processing of a primary artificial microRNA, leading to potent pharmacological activity for HTT lowering.
Research provides first direct evidence of volatilization of control rods during the FDNichi meltdowns, suggesting that boron remains in the fuel debris. This could limit fission reactions, but extensive follow-up studies are needed to characterize boron species across debris fragments.
A novel technique transplants patient fat into the sole to reduce plantar fasciitis symptoms, improving quality of life and sports activities. The study laid groundwork for a larger clinical trial with promising results.
A recent survey by Johns Hopkins Medicine researchers found that about 22% of young sexual minority males and transgender females engage in transactional sex. The practice is associated with HIV exposure, substance use disorder, and unstable housing. Researchers plan to develop interventions to address economic and social vulnerabilities.
A meta-analysis of 87 surveys from 35 African countries found that nearly one in ten sexually active men have paid for sex and are 50% more likely to be living with HIV. Men who pay for sex should be recognized as a priority population for HIV prevention efforts.
Researchers at the University of Delaware created a web-based educational model, Clerytown, to illustrate virus spread and inform policy changes. The model uses artificial intelligence algorithms to simulate community spread based on behaviors such as mask-wearing and social distancing.
A new meta-analysis of available literature on ALS disease has identified a group of seven environmental chemicals as correlates with increased risk of developing ALS. Exposure to these chemicals, including BMAA and heavy metals, may be contributing to the disease burden in certain regions.
Emerging research suggests that nutritional components can influence mitochondrial repair and preservation, quality control, and signaling to support healthy aging. Compounds such as SS peptides, CoQ10, and sirtuins have been shown to address mitochondrial damage and clinical disease states.
The new guideline provides a comprehensive summary of the state of evidence for managing patients with type B aortic dissection. It recommends employing a stepwise approach to evaluation and treatment, followed by close clinical surveillance, and identifies earlier endovascular treatment as a promising option.
A study by MIT scholars found that voting by incarcerated people in Maine and Vermont has significantly lower turnout rates compared to the general population. The researchers suggest that reinstating voting rights for this population may not yield a significant number of new voters, highlighting the challenges of disenfranchisement.
Researchers from China use digitalized flow rates to study the effect of exercise on plaque formation in carotid arteries, which carry blood to the head and neck. The study investigates how geometrical features of the arteries affect plaque formation and finds that exercising decreases reversed flow volume in older age groups.
A new AI-based method has been developed to evaluate patients with Stargardt disease, a leading cause of childhood blindness. The study found that the severity of vision loss can be classified into different phenotypes based on genetic variants, and provided sensitive structural outcome measures for therapeutic trials.
A recent study suggests that a chemical compound called magnesium hydrosilicate, stable at high pressures and temperatures, could have stored water deep within the Earth's mantle during its violent early days. This finding has significant implications for understanding the origin of water on Earth and potentially habitable exoplanets.