Researchers developed an indentation test to evaluate mechanical properties of sulfide solid electrolytes, crucial for all-solid-state lithium-ion secondary batteries. The method enabled accurate assessment in inert atmosphere, confirming superior mechanical properties of sulfide-type solid electrolytes.
A new retrospective cohort study analyzed data from over 4.5 million adult cancer patients, revealing a significantly higher risk of cardiovascular mortality and events following a new cancer diagnosis. The study highlights the need for a collaborative approach to healthcare for cancer patients and survivors.
Researchers describe a newly discovered saber-toothed mammal from the Eocene Period, offering insights into the evolution of meat-eaters. The fossil, Diegoaelurus vanvalkenburghae, was found in San Diego County and features specialized teeth for slicing flesh.
Researchers at the University of Ottawa developed a spray-on technology using customized nanogold and peptides that can restore heart function and electrical conductivity in damaged hearts. The therapy showed promising results in lab mice, with no off-target organ infiltration by tiny gold particles.
Researchers at the University of Bristol have identified a key pathway in the brain that underpins anxiety and fear behaviors. The discovery provides a novel target for developing better treatments for anxiety disorders, which affect an estimated 264-million people worldwide.
Scientists have developed a new synthesis method for phase-controlled Pd-Te nanoparticles that outperforms traditional methods. The fast, solvent-free approach uses microwaving to create high-activity catalysts for glycerol and ethylene glycol oxidation reactions.
Researchers found that adjuvant radiation therapy compared to early salvage therapy reduced mortality risk in men with pN1 prostate cancer. The study, published in the Journal of Clinical Oncology, showed a 8% decrease in mortality for each additional positive pelvic lymph node found at surgery.
Research reveals significant socioeconomic disparities among US medical students, with high-income students overrepresented across racial and ethnic groups. Low-income students remain underrepresented, despite efforts to address this issue.
A new study found that heavy traffic near roads is a significant contributor to water pollution, with contaminants from vehicle fluids, paints, and tires affecting nearby rivers. The study suggests that these pollutants come from road surfaces and are transported to watersheds through stormwater run-off.
Scientists at George Mason University are developing a therapeutic drug to replace BRCA1 in women deficient, offering an alternative for patients resistant to tamoxifen. The team aims to define the structural features of BRCA1 and identify specific cancer stem cells to target, providing a personalized and precision medicine approach.
A new study by University of Alberta researchers estimates that excessive sugar consumption in Canada results in $5 billion annual healthcare costs due to 16 chronic diseases. Limiting free sugar intake could reduce diabetes prevalence by 27% if Canadians follow the 10% recommendation, and 44.8% if they limit consumption to less than 5...
A study has decoded the DNA of the Arabian Oryx, a vulnerable species that was on the brink of extinction. The researchers analyzed the genetic data to inform breeding programs and found moderate diversity in the population's gene pool.
A surge in travel activity beyond pre-pandemic levels, known as 'anthropulse', is imminent, posing risks to the environment. Researchers are eager to study and document these impacts to inform sustainable future planning.
Researchers find controlling humidity in air conditioners causes roughly half of energy-related emissions, with temperature control causing the other half. New technologies like liquid desiccant-based cooling cycles could improve efficiency by 40% or more.
A recent commentary by Dartmouth College's Bala Chaudhary highlights the challenges faced by women researchers who choose to get married and change their last names. The lack of a consistent way to update publication records can lead to biases in grant and tenure applications, potentially affecting career advancement.
Researchers from the University of Cambridge and Disney Research developed a new method to display highly realistic holographic images using holobricks that can be stacked together. This technology has the potential to support large-scale holographic 3D displays with high-quality visual experiences.
A multicenter study found that COVID patients on ventilators often take weeks to regain consciousness after removal of respiratory support. The study also discovered a correlation between blood oxygen levels and the time it takes to recover, with patients experiencing more episodes of low oxygen taking longer to wake up.
Researchers at University of Queensland have identified a genetic basis for the increased risk of epithelial ovarian cancer in women with endometriosis. The study found genes that could be targeted to treat both conditions, increasing understanding and treatment options.
The authors advocate for integrated programs to diagnose, vaccinate, and manage HIV and COVID-19 patients, building on successful donor initiatives like PEPFAR and GFATM. This approach is crucial to address the intersecting pandemics and their detrimental effects on global health.
Researchers review current status of nanoparticle-enhanced photothermal therapy and photodynamic therapy, combining the two techniques to achieve highest treatment efficiency. Nanoparticles can deliver drugs or antibiotics to inaccessible sites, creating a more powerful treatment method.
Researchers found that sequencing drug combinations can enhance the anti-tumor immune response in liver cancer, potentially reducing toxic drug exposure. The new strategy primes the tumor with an immune checkpoint inhibitor before using a multikinase inhibitor, enhancing its effectiveness.
Researchers found that low blood oxygen levels correlate with longer time to regain consciousness in patients with severe COVID-19. The study involved 795 patients and found that 72% recovered consciousness before hospital discharge, but 25% took 10 or more days to recover.
A new UMaine study shows that a specific combination of pathogens and drugs can effectively treat fungal lung infections. Researchers found that Pseudomonas aeruginosa works with fluconazole to eliminate drug tolerance and clear Candida albicans infection, suggesting that nutrient availability can impact treatment efficacy.
Researchers discovered that certain snakehead species, including the kampango catfish, produce and provide trophic eggs as supplemental nutrition for their offspring. This unique adaptation likely enabled these fish to conquer new environments and lead to the high diversity of species in this group.
Researchers assessed risk factors associated with mortality and neurologic disability three months after intracerebral hemorrhage, finding a link between certain comorbidities and poor outcomes. The study used a racially and ethnically diverse cohort to identify key risk factors for death and disability.
Researchers developed a method to modulate molecular orbital energies, charge transport capacities, and spin electron densities of active units in covalent organic frameworks. This approach improves the stability of organic radicals and enhances the redox activity of COFs, leading to optimized lithium ion storage.
Researchers developed an optimizer tool to design and evaluate solar-powered adsorption cooling systems, achieving higher coefficient of performance with certain material combinations. The study focused on residential home cooling systems but aims to be extended to higher capacity systems.
A new study by Giada Di Stefano found that the Michelin Guide's arrival triggers changes in fine dining industry competitive dynamics. Restaurants modify their descriptions and pricing to signal awareness of value created for customers, with those already highly ranked emphasizing authenticity and exclusivity.
Scientists at Sandia National Laboratories have developed a tiny device that can shunt excess electricity in a few billionths of a second, protecting the nation's electric grid from electromagnetic pulses. The diode operates at a record-breaking 6,400 volts and has potential to operate up to 20,000 volts.
A team of scientists has reported new research progress on the photoluminescence (PL) mechanism of carbonized polymer dots (CPDs), uncovering the essential roles of spatial effects within confined domains. The study reveals tunable PL performance through varying degrees of steric hindrance.
New research suggests that routine mammograms can provide key insights into a woman's risk of cardiovascular disease. The study found that detection of breast arterial calcifications on mammograms was associated with a higher risk of heart disease and stroke in postmenopausal women.
EULAR has updated its COVID-19 vaccination recommendations for people with rheumatic and musculoskeletal diseases, based on emerging evidence and expert opinion. The new guidelines emphasize the importance of vaccination in preventing infection and improving outcomes.
A study found that people living within 300 meters of green spaces have a 16% lower risk of ischemic stroke. The researchers suggest that the current European Union air pollution limits for nitrogen dioxide and particulate matter need to be reconsidered due to the direct relationship between exposure to these pollutants and stroke risk.
A new study finds that immediate action to reduce methane emissions could preserve Arctic summer sea ice through 2100, with drastic cuts in CO2 also necessary. The chances of saving summer sea ice increase from nearly zero without action to over 80% if net zero CO2 emissions are reached by 2050.
A new study published in Annals of Internal Medicine found that state laws regulating opioid prescriptions had no effect on prescribing patterns for commercially insured adults with chronic non-cancer pain. The study suggests that declines in opioid prescribing may be driven by shifting clinical guidance or other factors.
Researchers at WorldPop created high-resolution population maps of the Democratic Republic of Congo using satellite imagery and small-scale household surveys. The study estimates population counts and age structures across multiple provinces, helping governments plan public health programs and infrastructure projects.
A new research project aims to introduce low-carbon concrete elements with high resource utilisation by reusing entire concrete elements from existing buildings as load-bearing structures in new buildings. The entire value chain is represented in the project.
A new manifestation of COVID-19 has been identified in young children, characterized by croup, a common respiratory illness marked by a distinctive barking cough. The omicron strain's preference for the upper airway may account for the sudden appearance of croup during the surge.
A study has found that lead poisoning from gun ammunition has suppressed the populations of birds of prey across Europe, resulting in a loss of around 55,000 adult birds. The impact is particularly significant for species like eagles and Red Kites, which are long-lived and breed later in life.
Researchers at Lewis Katz School of Medicine identify reduced efficiency of protein transport system as key factor in Alzheimer-like changes. The study suggests that targeting the retromer complex could lead to new treatments for Down syndrome-related dementia.
A team of researchers found significant differences in lipid profiles between sperm and erythrocytes, with more closely related species showing similarities. The study's results help improve understanding of oxidative stress on reproductive processes and assisted reproduction measures.
Researchers found a connection between how people think about their finances and their financial behaviors. Identifying situations when spending patterns are likely to occur can help predict triggers.
Research published in RMD Open found a link between long-term exposure to traffic and industrial air pollutants and an increased risk of autoimmune diseases. Exposure to PM10 above 30 µg/m3 was associated with a 12% higher risk of autoimmune disease, while exposure to PM2.5 above 20 µg/m3 was associated with a 13% higher risk.
Researchers at Université catholique de Louvain have discovered a drug called MitoQ that prevents the appearance of metastases and local recurrences in human breast cancer. The molecule stops cancerous stem cells from awakening, offering a new treatment option for patients.
Researchers found a high prevalence of long-lasting air trapping and small airways disease in COVID-19 survivors, regardless of initial infection severity. The study suggests that persistent respiratory symptoms may be related to inflammation or fibrosis of the small airways.
Children with high diastolic blood pressure scores had reduced risk of in-hospital mortality and reduced time in the ICU and hospital after CHD repair surgery. Predictive models could be improved by adding blood pressure polygenic risk scores to identify children at risk for adverse outcomes.
Syrian refugee women in Houston experience significantly higher mental stress, including depression and anxiety, due to displacement and social strain. They face challenges such as language barriers, unemployment, and financial insecurity, which contribute to their high-stress environment.
Researchers found that Rett syndrome mice have larger and more correlated ensembles of neurons, suggesting reduced inhibition. Activating somatostatin-expressing inhibitory neurons improved contextual memory recall in Rett mice.
The CSD-Materials suite provides a comprehensive analysis of solid form properties, helping researchers explore intra- and intermolecular interactions. The suite's components, including Hydrogen Bond Propensity, Full Interaction Maps, and Aromatics Analyser, aid in identifying potential co-former or solvent interactions for new APIs.
A new study published in Neurosurgery found that even moderate COVID-19 infection increases the risk of death in younger, healthier stroke patients. The research examined 575 patients with severe stroke and found that COVID-19 patients were nearly 10 years younger and had fewer cardiovascular risk factors.
The Wilderness Medical Society has published evidence-based guidelines for anaphylaxis treatment in remote areas. The guidelines recommend administering intramuscular epinephrine as the primary prehospital treatment, while also discussing prevention strategies such as extracting additional epinephrine from autoinjectors and using expir...
A study published in Cell Reports Medicine reveals the oncometabolite role of progesterone in advanced prostate cancer and strategies to eliminate its oncogenic effect. Biochanin-A, an isoflavone found in soy, inhibits the enzyme 3βHSD1, which generates progesterone.
Researchers have invented an advanced brain-computer interface with a flexible and moldable backing, allowing for more even conforming to the brain's complex surface. The device records signals from nearby nerve cells evenly across a wide area of the cortex, outperforming existing gold standard technologies.
Scientists have identified a potential new test for diagnosing Lyme disease by detecting autoantibodies to phospholipids. This approach could help clinicians diagnose the disease sooner and determine efficacy of treatments. The researchers' discovery has the potential to identify patients with persistent symptoms after treatment, makin...
A new study finds that mentalizing imagery therapy (MIT) significantly reduces depression, anxiety, and improves well-being in family caregivers. The therapy teaches mindfulness and guided imagery skills to help caregivers better understand their loved ones and manage chronic stress.
A recent study from the University of Toronto's Rotman School of Management found that slow stock analysts outperform their faster counterparts. Portfolios that follow their advice have been shown to perform five to 10 percent better, thanks to their ability to assess a company's value and update forecasts more frequently.
Researchers found a strong connection between retinal layer thickness and brain volume, suggesting retina assessments as a potential biomarker for brain atrophy. Thinner retinal layers correlated with reduced brain white matter and hippocampus volume.
The African BioGenome Project aims to sequence the genomes of Africa's endemic plants, animals, fungi, and protists. This will build resilience in breeding, sustainable food systems, and biodiversity conservation, aligning with the post-2020 Global Biodiversity Framework and the United Nations Sustainable Development Goals.
Scientists have identified three active compounds in sex pheromones of the world's largest hornet, Vespa mandarinia, to attract males and control its reproduction. The discovery could aid in monitoring and controlling the invasive species' spread in North America.
A new research study by the University of Massachusetts Amherst fundamentally changes our understanding of how salt marshes acquire sediment. The majority of sediments are delivered by the ocean during storms, reversing commonly held assumptions about the role of rivers in building and maintaining these ecosystems. This discovery has s...