A novel algorithm uses near-infrared spectroscopy to estimate intracranial pressure (ICP) based on hemoglobin levels. The research validates the accuracy of this method using invasive ICP data.
A new study has identified a specialized and distinctive type of microglia with enhanced antioxidant function in the ischemia/reperfusion injured brain, linked to stroke. The presence of Peroxiredoxin-1 protects against acute I/R injury, reducing microglial cell death and inflammatory responses.
Sharing real-time air quality readings can reduce fine particulate concentration levels by 2-4 micrograms per cubic metre each year, leading to significant health benefits. The research estimates annual health benefits of $171 million AUD for the median city.
Researchers developed a computational protocol called MACH that can quickly determine whether a given compound will form a crystal hydrate. The tool uses rules to systematically determine where water would likely be inserted into a crystal, providing essential knowledge for drug development and formulation.
Researchers from University of Warsaw create spiking neuron using photons to mimic biological brain's behavior. This achievement paves the way for photonic neural networks that process information faster and more efficiently than conventional systems.
The Canadian Medical Association Journal (CMAJ) publishes special issues on the impact of anti-Black racism on patient health and healthcare professionals. Research by Black health scholars and practitioners sheds light on systemic inequities, including cancer care disparities and gaslighting in academic medicine.
Amino acid GABA shows promise in reducing disease severity, viral load and death rates in SARS-CoV-2-infected mice. GABA administration inhibits inflammatory actions of immune cells, potentially providing a generalizable therapy to treat COVID-19 and future novel coronaviruses.
A new study published in iScience found that humans tend to follow a two-step process when in a crowd, with an initial reflexive imitation followed by a more deliberate strategic decision. The research suggests this influence affects not only social norms but also immediate actions and underlies behaviors such as rioting and mass panic.
Researchers at Sandia Labs have successfully built a compact, rugged quantum inertial sensor that can guide vehicles without satellites. The device uses advanced materials and integrated photonic technologies to achieve high accuracy and miniaturization.
Researchers created a 3D brain atlas to study neuronal differentiation and growth in vertebrates. The atlas allows visualization and quantification of parameters that couldn't be seen before, revealing the relationship between birth time and place and neuron position in the tissue.
A new study in Cell Systems explores the benefits of using multiple data types in drug discovery. Gene expression and cell morphology provide complementary information for drug prioritization, advancing drug discovery, functional genomics, and precision medicine.
Researchers at the University of Copenhagen have made a breakthrough in understanding schizophrenia by analyzing individual brain cells. The study identified specific neurons and networks affected by the disease, suggesting that targeting these areas could lead to new treatment options.
George Mason University researcher Kenneth Dere has received funding from NASA to revise ionization rates and develop software for the CHIANTI database. He will integrate measured cross-sections into the database, calculate a new ionization equilibrium, and write a scientific paper detailing his findings.
Researchers have uncovered the neural mechanisms behind sound perception, finding that the brain predicts expected sounds and responds to unexpected ones. The study provides insights into how the healthy brain learns complex skills and may offer clues for understanding neural disorders like schizophrenia.
A plant-based diet significantly reduced advanced glycation end-products (AGEs) by 79%, associated with weight loss and improved insulin sensitivity. The reduction in AGEs was largely attributed to decreased meat and dairy consumption, leading to a 14-pound weight loss.
A randomized phase III trial found that hypofractionated whole-breast radiation with concurrent boost is comparable to six weeks of treatment for patients with higher-risk disease, reducing tumor recurrence by 20-30%. The three-week course was non-inferior to the longer treatment in terms of tumor recurrence and cosmetic outcomes.
Researchers identified specific transcription factors involved in RA's heterogeneity and stratified cell lines into subtypes with distinct predicted activated pathways. This could help pave the way for personalized treatments tailored to individual patients' needs.
A study from Boston University School of Medicine has identified a receptor called CD169 that plays a key role in the hyper-inflammatory response of macrophages upon infection with SARS-CoV-2. This finding may provide an explanation for how the virus promotes inflammatory responses in COVID-19 patients.
Researchers found that high nutrient inputs result in a decline of plant species, with more species getting lost and fewer new species arriving. This study provides valuable information for practical nature conservation by understanding the effects of unnatural nutrient inputs on biodiversity.
Lei Yang is conducting research on developing fair AI-assisted mobile dermatology diagnosis technology using unsupervised federated learning. The goal is to ensure participation from all socioeconomic populations and find the best network while considering hardware constraints.
Research reveals that α-Ketoglutarate (AKG) supplementation promotes skeletal muscle mass, improves exercise endurance, and increases blood flow, making it a potential nutritional supplement for enhancing health and exercise performance. AKG also relaxes vascular smooth muscle, allowing tissues to receive abundant oxygen and nutrients.
Researchers from Hokkaido University have identified a link between succinyl-CoA levels and energy metabolism in heart cells affected by chronic heart failure. Supplementation with 5-aminolevulinate acid improved heart function and oxidative phosphorylation capacity in mice with surgically blocked blood supply.
A new study found that gestational exposure to the flame retardant FM 550 resulted in altered brain development in newborn rats, with effects more pronounced in male offspring. The study also showed evidence of mitochondrial disruption and dysregulated choline and triglyceride levels in brain tissue.
Researchers analyzed three intervention strategies to mitigate mercury use and emissions in artisanal gold mining, finding that while some methods reduce emissions, others create new environmental problems. The study suggests a need for more comprehensive approaches to address the complex issues surrounding mercury use.
Researchers have developed an intranasal COVID-19 vaccine that works against the original virus and two variants, including omicron, in hamsters. The vaccine stimulates a strong immune response both systemically and in the respiratory tract.
A qualitative study reveals that low-income Black pregnant people face suboptimal prenatal care, emphasizing the importance of integrated services addressing social needs and preferences. Healthcare workers also report challenges in meeting patients' needs, underscoring the need for improved care delivery models.
Researchers at HZB develop tandem solar cells using perovskite and silicon, achieving record-breaking efficiencies of up to 29.8%. Customized nanotextures improve perovskite semiconductor materials by reducing reflection losses and parasitic absorption.
University of Iowa researchers confirmed a neural circuit linking two brain regions that governs how animals react to stressful situations. The study showed that activating this pathway can revive active coping behaviors and reduce stress hormone release in rats.
Researchers suggest that prescribed fire can help restore forest habitats less favorable to disease-carrying ticks, reducing their populations. Fire-driven forest modification can also suppress tick abundance and pathogen transmission by creating drier conditions and increasing wildlife predators of ticks.
A study by Max Planck Researcher Jonas Schöley and colleagues found that life expectancy continued to decline globally in 2021, with differences between Eastern and Western Europe widening. However, vaccination efforts helped mitigate mortality shocks in some countries, particularly those with robust healthcare systems.
A study of 16 cats found they can differentiate their owner's voice from a stranger's, even when tone is changed. This suggests that cats form strong bonds with their owners based on experience of the speaker's voice.
Researchers used big datasets to show that annual health care costs were significantly higher among children without allergist care for peanut allergy compared to those who received care. Care from an allergist resulted in lower total health care costs, saving $1,923 per child.
Research found that new autism diagnoses tend to cluster within specific NHS service regions, suggesting a possible health service effect on diagnosis rates. This study highlights potential healthcare disparities and the impact of social determinants on autism diagnosis likelihood.
Researchers at Carnegie Mellon University have developed a new approach for conducting automated science in space by balancing risk and scientific value. The approach uses a model that estimates science value and risk, allowing rovers to chart their own course while protecting against high-risk missions.
Scientists have developed a theory that allows flying insects and drones to estimate the gravity direction without accelerometers. The approach combines visual motion sensing with a motion model, enabling drones to predict their attitude and navigate in cluttered environments.
A team of scientists has discovered that repurposing CO2 from building exhaust as a fertilizer can help plants on rooftop farms grow larger and healthier. Studies found that spinach grown next to the vents had four times the biomass of controls, while corn also showed significant growth advantages.
A recent study found that video gamers exhibit better cognitive performance compared to non-gamers, especially in response inhibition and working memory skills. The study also identified alterations in brain regions responsible for visual attention and memory processing.
A novel oxytocin derivative, PAS-CPPs-oxytocin, has been shown to improve cognitive function in mice with Alzheimer's-like symptoms. The derivative is delivered via intranasal administration and shows increased brain penetration compared to traditional intracerebroventricular delivery.
A new study by the University of Waterloo found that individuals with anxiety disorders are not more hesitant to get vaccinated than those without. Instead, discomfort with uncertainty is a significant predictor of vaccine hesitancy in both anxious and non-anxious individuals.
Researchers at the University of Sydney have developed a method to manufacture materials that mimic the structure of living blood vessels, with promising implications for future surgery. The technology allows the body to accept and transform the implanted material into a functional 'living' blood vessel.
Researchers developed a machine learning-based diagnostic method that combines genomic sequencing and analysis of patients' immune response for remarkable accuracy. The approach identifies and predicts sepsis cases with high accuracy, potentially exceeding current diagnostic capabilities.
Researchers found that reactivating memories during sleep improves memory storage by triggering electrical activity in the brain. The study, led by Northwestern University, used implanted electrodes to record brain activity in five patients while they slept and presented sounds associated with learned objects.
A pooled data analysis found that workplace exposure to gases, fumes, and aromatic solvents is associated with a decline in lung capacity. Regular check-ups are recommended for workers in these environments to prevent respiratory illness.
Scientists have found a way to produce high-performance magnets without rare earth elements, using the 'cosmic magnet' tetrataenite. The discovery could reduce reliance on China's dominant rare earth supply, supporting low-carbon technologies.
A randomized phase III trial shows that adding radiation therapy to systemic therapy can delay tumor progression and lengthen survival without compromising quality of life. The combination of SBRT and sorafenib appears more effective than the drug on its own.
Research suggests that regular physical activity enhances vaccine effectiveness against COVID-19 by improving antibody levels and mitochondrial function. High levels of physical activity were associated with higher vaccine protection rates, with significant reductions in hospital admissions and severe illness risk.
Researchers aim to improve grid flexibility by reducing motor aging and increasing renewable energy utilization. They develop a numerical model to predict electric motor aging under different control conditions, promoting widespread adoption in electricity markets.
A new theory by UMass Amherst sleep scientist Rebecca Spencer suggests that young children's brain development, not age, determines when and why they stop napping. The hippocampus, a memory area of the brain, plays a critical role in nap transitions.
A new study found that offshore mussel farms can increase species abundance, including Atlantic horse mackerel and European lobster, on degraded seabed habitats. The research suggests that this practice could have wider environmental benefits, supporting the national and international Blue Growth agenda.
A study of the Skaftö wreck's cargo has provided new insights into 15th century trade routes. The research team mapped the origins of its cargo, including copper mined in Slovakia and Poland, and quicklime from Gotland, indicating that the ship took on cargo in Gdańsk before heading to Western Europe.
Researchers at UTIA are studying feed efficiency in pregnant Angus heifers to improve the overall sustainability of beef production. The team is examining the impact of pregnancy on rumen environment and nutritional changes, aiming to provide producers with strategies to improve feed efficiency and calf quality.
Researchers have made significant advances in understanding ESMPT in organic molecules through a combination of experimental and theoretical methods. This includes the development of new materials with potential applications in near-infrared organic lasers and light-emitting self-luminous liquid crystal devices.
A new Harvard-led study has found evidence of early plate tectonics and the flipping of Earth's magnetic poles, which may have created a more conducive environment for life. The research suggests that the planet's surface was moving at a rate of 6.1 centimeters per year, consistent with modern plate tectonics.
Researchers developed a new method to study membrane proteins in their native environment, the cell, using electron spin resonance spectroscopy. This technique allows for precise determination of protein properties and could lead to better understanding and targeting of membrane proteins involved in anti-cancer drug resistance.
Researchers found that adult heart cells have fewer communication pathways called nuclear pores, which may protect against harmful signals but prevent regeneration. This discovery sheds light on why adult hearts do not regenerate like newborn mice and human hearts.
George Mason University's Maibach and Mitchell receive $700,001 funding from Robert Wood Johnson Foundation to promote equitable climate and health solutions in the Gulf States. The funding will support the expansion of the Medical Society Consortium on Climate and Health until September 2024.
A Phase III trial found that hypo-fractionated whole breast irradiation (WBI) with concurrent boost is not inferior to conventional WBI with a sequential boost following lumpectomy in patients with high-risk, early-stage breast cancer. The study showed comparable effectiveness and toxicity outcomes between the two treatment options.
A recent study by University of Gothenburg researchers found that nearly twice as many Swedes are willing to obtain antibiotics without prescriptions than previously thought. Trust in healthcare plays a significant role in this behavior, with low trust linked to increased prescription without a doctor's order.
Researchers developed a compact robotic finger with adjustable stiffness to withstand physical impacts and mimic human finger dexterity. The finger mechanism is based on gear transmission and mechanically passive compliance, providing an advantage in terms of reliability, ease of manufacture, and maintenance.
A Cornell University researcher is using optical microscopy and other tools to map the brain's neural response to psychedelics. The study aims to develop fast-acting antidepressants and treatments for substance-use disorders and cluster headaches.