A recent study by Boston Medical Center and Boston University's Center for Regenerative Medicine discovered that hemogenic endothelial cells in the fetal lung contribute to blood cell formation. This breakthrough expands our understanding of blood development and its relationship with overall health.
Researchers found substantial associations between donations and policy priorities expressed in congressional speeches, marking a viable arena for studying the impact of donors on congressional behavior. Businesses donate more to legislators than labor unions, with a stronger association with issue-attention.
Researchers developed an advanced terrain-smoothing technique to simulate complex weather phenomena, capturing detailed flow features and turbulence. The targeted smoothing method improves the accuracy of downslope windstorm predictions in urban areas, holding promise for more accurate weather forecasts.
Scientists have identified a DNA methylation pattern that can accurately diagnose pancreatic cancer, distinguishing it from chronic pancreatitis. The marker, which involves six specific methylation positions in the PRKCB gene, has been validated on tissue and blood samples, offering hope for improved diagnosis and treatment.
A new three-year grant will provide specialized dementia services and supports to underserved communities in Broward County. The project aims to improve quality of life for individuals living with or at risk of Alzheimer's disease, as well as their family caregivers.
The study reveals that while CTFs showed small increases in saved sums, many accounts remained untouched and parents had forgotten or lost track of them. The research calls for revisiting the principles behind the programme to improve UK's financial resilience.
Researchers have identified a pattern of brain activity, or biomarker, related to clinical signs of recovery from treatment-resistant depression. The study found that 90% of patients showed significant improvement in depression symptoms after six months of DBS therapy.
The rock-climbing fish's setae structures convert water contact into a sticky gel-like substance, enabling dynamic adhesion. The Climbot robot replicates this mechanism to achieve tight adhesion on moving surfaces.
A randomized controlled trial found that cognitive behavioral therapy (CBT) significantly reduces fibromyalgia pain by decreasing pain-catastrophizing, a negative response that amplifies pain. CBT participants showed reduced connectivity between brain regions associated with self-awareness and emotional processing.
Research at the University of Southampton found that 12-hour plus shifts increase incidents of self-harm, threatening behavior, and violence. The study suggests that nurse managers should avoid implementing long shifts as a blanket solution.
A team at DGIST discovered a method to enhance magnetic nanoparticle penetration into cancer cells, improving therapeutic effects. Rotational magnetic fields aid in chain disassembly and propulsion of magnetic nanoparticles, increasing cellular absorption and treatment efficacy.
Researchers found that huckleberry patches and forestry road density significantly affect grizzly bears' mortality risk. Securing critical food resources through reduced human access near roads is crucial for bear conservation.
A large study published in Journal of Investigative Dermatology found that patients with severe psoriasis have a high prevalence of coronary microvascular dysfunction, which is associated with increased cardiovascular risk. Psoriasis severity and duration, as well as the presence of psoriatic arthritis, are independently linked to redu...
A new molecular mechanism has been identified that helps plants adjust protein levels to fight infection. By unzipping specific RNA structures, plant cells can produce defense proteins. This discovery also has implications for human cells, suggesting a similar mechanism may control protein production in response to pathogens.
A recent study suggests that higher intake of ultraprocessed foods, particularly those with artificial sweeteners, may be associated with an increased risk of depression. The exact mechanism is unknown, but researchers believe that artificial sweeteners could play a role in the development of depression.
Researchers found that two common songbirds have smaller eyes than their counterparts from less bright outskirts, adapting to urban light. This study suggests that sensory pollutants like human-caused light may play a role in the decline of bird populations.
The NIH award will explore how damage to mitochondria affects bioenergetic function and organ function, leading to disease severity and failure. The study aims to better understand mitochondria mutations and develop new therapies for patients with mitochondrial disorders.
A newly discovered virus has been isolated from deep-sea sediment, providing insights into the diversity and evolution of viruses in extreme environments. The bacteriophage, which infects bacteria in the phylum Halomonas, is believed to be one of the most abundant life forms on the planet.
A study found sociodemographic-based disparities in COVID-19 therapeutic drug availability, revealing gaps in treatment access. The research highlights the need for targeted interventions to address these disparities.
Researchers at the University of Cambridge have made a groundbreaking discovery that could lead to more effective treatments for neuroblastoma, a devastating form of childhood cancer. The new approach uses a combination of two drugs to encourage cancer cells to become normal non-dividing cells, potentially reducing side effects.
The UMass Amherst-UT Austin team has been awarded $27.5 million by the CDC to establish the nation's first disease outbreak response and modeling network. The $250 million program will support decision makers during public health emergencies like COVID-19.
Researchers have identified new genetic markers to detect Lynch syndrome-associated colorectal cancer with 92% accuracy. The discovery could lead to a non-invasive screening option using stool samples, reducing the need for annual colonoscopies and invasive tests.
Researchers from Tokyo Tech have developed an organic light-emitting diode (OLED) with a remarkable ultralow turn-on voltage of 1.47V for blue emission. The device uses upconversion mechanism to reduce applied voltage, enabling efficient blue OLED production.
The discovery of well-preserved wood at Kalambo Falls in Zambia reveals that humans were building structures made of wood at least 476,000 years ago. This finding challenges the long-held assumption that Stone Age humans were nomadic, as they had access to a perennial source of water and food in the forest.
The American Academy of Neurology has outlined a comprehensive plan to boost brain health by 2050, emphasizing preventive care and scientific discovery. The vision aims to optimize neurologic function across all stages of life, fostering physical, mental, and social well-being.
Scientists at OHSU elucidated the structure of Type A GABA receptors targeted by antidepressants and other pharmaceutical drugs, shedding light on their role in brain function and development. The study reveals dominant assemblies and states of the receptor, paving the way for the development of new compounds with improved efficacy.
Research by the University of Leeds found that fathers who engage in interactive activities with their children, such as reading and playing, have a positive impact on their educational achievement. The study suggests that even small changes in father-child interaction can have lasting benefits for children's learning.
Researchers at ETH Zurich have created a method to simultaneously modify multiple genes in individual cells of an animal, allowing for the study of complex diseases. By precisely analyzing these cells, scientists can identify key genes responsible for disease progression, paving the way for potential drug development.
A new analysis of COVID-19 cases in Africa found that the rate of infection was likely much higher than reported in the initial stages. The researchers estimated that approximately 66% of all infections were asymptomatic, while about 5% were severe and 27% were mild.
A new study found that multiyear La Niña events have become more common over the last 100 years, with warming in the western Pacific Ocean being a key factor. The study suggests that long-lasting La Niñas will exacerbate adverse impacts on communities around the globe.
Researchers found that ancient Amazonians intentionally created dark earth by modifying the environment to improve soil fertility. This practice allowed for large and complex societies to thrive, with stored carbon remaining in the soil for hundreds to thousands of years.
New hybrid membrane technology uses thermosalient organic crystals to effectively remove contaminants from surfaces, increasing water flow by over 43% and extending operational lifetime. This innovation has the potential to make desalination technologies more efficient and environmentally sustainable.
Ya-Chieh Hsu and Xuebing Wu receive $525,000 grants to explore genes that rejuvenate aged stem cells and investigate the role of noncoding translation in aging. The awards aim to advance research on mechanisms governing normal human aging.
Researchers found that inhibiting isocitrate dehydrogenase in T cells leads to transformation into memory cells with enhanced anti-tumor activity. This discovery could improve CAR-T and other adoptive cell therapies by overcoming exhaustion.
Researchers found that intermittent shading can moderate coral bleaching on shallow reefs by reducing light stress. Shading corals for four hours a day reduced bleaching in some species, while longer periods of shading showed more significant results.
A novel method of analyzing Mars' gravitational force confirms the presence of an extensive northern ocean, providing new insights into the planet's history. The approach differs from traditional methods and can be applied to various disciplines such as geology and hydrology.
Lehigh University researchers have discovered that applying magnetic forces to individual 'microroller' particles can spur collective motion, allowing the grains to flow uphill, up walls, and climb stairs. This counterintuitive phenomenon has potential applications in mixing, segregating materials, and microrobotics.
A joint study by multiple research teams identified a link between valproate exposure during pregnancy and increased expression of the Rnf146 gene in autism mice, disrupting neurotransmitter balance. The findings contribute to understanding autism's mechanism and may aid early detection and treatment.
A study reviewing current research on ADHD in older adults highlights the need for better approaches to screening and diagnosis. The authors conclude that existing guidelines focus on children and young adults, leading to a lack of consideration for the condition in people aged 50-55.
Scientists successfully detect local chemical pressure using an optical probe, enabling the simulation of physical pressure effects. The technique holds promise for exploring metastable phases and achieving room-temperature superconductivity.
Researchers used AI to predict 3D shapes of over 215 million proteins, providing insights into their functions and evolution. The Protein Universe Atlas offers a valuable resource for scientists to explore protein diversity.
New research from The George Institute for Global Health suggests applying Google's nutrition advertising policy in the US market could reduce products eligible for online marketing to children, leading to significant health gains. Only 18% of products would be allowed under this policy.
The American Thoracic Society has partnered with five new health systems to identify barriers to vaccination and find ways to improve immunization rates. The initiative aims to increase COVID-19, flu, and pneumonia vaccine uptake among high-risk adults with respiratory diseases.
Researchers have developed an AI-based camera alert system to detect endangered species like tigers and elephants. The TrailGuard AI system transmits images to park managers in real-time, enabling rapid responses to poachers or human-tiger conflicts.
A new health care utility model called Civica Rx increases supply security and reduces costs for health systems, with increased access to critical medications. The model prioritizes access over profit and offers transparent pricing for all customers.
Researchers found that beta-blockers can revive exhausted killer T cells, making them better cancer fighters. The study discovered a link between the sympathetic stress response and immune system response to cancer.
A novel biodegradable optical fiber made from agar has been developed to measure or modulate electrical currents in the body. The fiber can be used to monitor bioelectrical stimuli produced in the brain or muscles, serving as a biodegradable alternative to conventional electrodes.
Researchers developed a DNA damage-induced senescence model in osteoarthritic chondrocytes, which reliably induces cellular senescence and accumulates senescent cells in OA joint tissues. The study provides a useful model to develop therapeutic approaches targeting senescence in osteoarthritis.
A new NIH study found an association between higher prenatal phthalate levels and a slightly increased risk of postpartum depression. Exposure to chemicals like phenols, phthalates, and parabens during pregnancy may influence hormone levels and contribute to the development of postpartum depression symptoms.
Researchers at Chalmers University of Technology have developed a new method to increase the efficiency of microcombs, raising their efficiency from around 1 percent to over 50 percent. This breakthrough enables high-performance laser technology for various applications in space exploration, healthcare, and other industries.
A new type of regulation is needed to support and encourage organisations to comply with equality and human rights law. The current enforcement pyramid fails to recognise innovation or good practice, instead relying on penalties that may deter staff from taking action.
Scientists at Oak Ridge National Laboratory have developed a technology that converts unrecyclable plastic waste into useful chemicals, reducing energy consumption and greenhouse gas emissions. This new approach presents a promising strategy for establishing closed-loop circularity of plastics and fighting global plastic waste.
A team of researchers has identified a unique pattern in brain activity that reflects the recovery process in patients with treatment-resistant depression. After six months of deep-brain stimulation therapy, 90% of patients exhibited significant improvement in their symptoms and 70% no longer met the criteria for depression.
A Tohoku University research team developed a technique to recreate water flow in real-time using only a small amount of data from real water. This technology enables the creation of immersive VR games with lifelike water motion, potentially enhancing online communication and remote interactions.
A new study reveals that people with high social vulnerability are more exposed to wildfires in Oregon and Washington, with the number of exposed individuals tripling between 2011 and 2021. The study highlights the need for tailored wildfire preparation and response strategies for individual communities with different risk factors.
Researchers developed a computational model to analyze glucose-responsive insulin (GRI) performance in human patients. The model predicted that differences in sugar receptor behavior between humans and lab animals led to the drug's poor effect in clinical trials. This breakthrough helps researchers design better GRIs, potentially reduc...
Researchers at the Swiss Cancer Center Léman have discovered a way to prolong the functionality of CAR-T cells, which are used against blood cancers. By inhibiting a specific metabolic mechanism, they created CAR-T cells with enhanced immune memory, capable of fighting tumour cells for longer.
Researchers have successfully developed a catalytic system to efficiently synthesize beta-lactam structures using abundant hydrocarbons as raw materials. The new catalyst eliminates the need for auxiliary attachment and removal, reducing the synthesis process from approximately eight steps to three steps.
A new study suggests that upgrading or retrofitting the world's iron and steel processing plants early could reduce carbon emissions by up to 70 gigatonnes by 2050. This is equivalent to two years' worth of net global carbon emissions, according to researchers from UCL.
Scientists have successfully produced a thin sheet of molybdenum, similar to graphene, with impressive properties. Molybdenene exhibits mechanical stability, freely moving electrons, and is an interesting candidate for catalysts and advanced imaging techniques.