A RAND Corporation study found that patient experiences with hospitals declined significantly during the COVID-19 pandemic, with deficits largest at lower-performing and understaffed facilities. Hospitals with higher staffing levels were more resilient but eventually reported worse experiences as well.
Researchers develop innovative framework to evaluate establishment risks linked to invasive golden mussels in water diversion projects. Key environmental variables identified, including total nitrogen levels and optimal water temperature, which impact mussel reproduction and biofouling risk.
The European Society of Cardiology calls for competency-based cardiac imaging delivery to enhance effective and efficient patient care. This approach enables cardiologists to deliver high-quality imaging services, select the most appropriate modality for each clinical scenario, and provide informed decision-making.
Brandon Carpenter, a Kennesaw State University professor, received a $432,000 NIH grant to continue his research on epigenetic states and their inheritance in nematodes. Students will use the microscopic Caenorhabditis elegans worm to study neurological disorders.
Researchers discovered that inhibiting IGF2BP1 can extinguish its cancer-causing effects, leading to the formation of neuroblastomas. The study provides a promising new potential therapeutic approach for treating this childhood cancer.
The American Dental Association has released a new clinical practice guideline recommending the use of acetaminophen and/or non-steroidal anti-inflammatory drugs (NSAIDs) as first-line treatments for managing short-term dental pain in children under 12. The guideline has been endorsed by the American Dental Association.
A new study found that mental health spending rose by 53% from March 2020 to August 2022 among privately insured Americans, with in-person care experiencing a significant increase. Despite plateaued telehealth use, overall mental health service use grew nearly 39%. The trend's sustainability remains uncertain.
Researchers at Massachusetts General Hospital have developed a novel 3D human cellular model that mimics the intricate interactions between brain cells and immune invaders, providing insights into how immune cells contribute to Alzheimer's disease progression. The study identified specific types of immune cells called CT8+ T Cells surg...
A focused update of the European Society of Cardiology (ESC) Heart Failure Guidelines incorporates latest evidence-based treatments for improved patient outcomes. New recommendations include SGLT2 inhibitors and intensive treatment strategies to reduce hospitalization and mortality.
A Rutgers-led study found a clear association between mental health disorders, cannabis use, and cannabis use disorder (CUD) among pregnant and postpartum women in the US. The research highlights specific types of mental health disorders linked to cannabis use and CUD.
The NSL complex controls intraciliary transport genes essential for cilia formation and function. Loss of the complex leads to impaired assembly and activation of these genes, resulting in ciliopathies characterized by hearing loss, visual impairment, and kidney disease.
The Texas Heart Institute has received a five-year, $2 million grant from the National Institutes of Health to advance organ bioengineering. The project aims to develop transplantable bioartificial hearts to combat end-stage heart failure.
The series emphasizes the importance of anesthesiologists in addressing unmet needs of patients with Substance Use Disorder (SUDs) in the perioperative period. Anesthesiologists are urged to adopt a broader approach to effective disease management, incorporating trauma-informed patient care and increased collaboration with addiction me...
A study found that China suffered an estimated 1.87 million excess deaths among individuals 30 years and older during the first two months after ending its zero COVID policy. The lifted policy led to a significant increase in mortality rates, highlighting the need for continued public health measures.
Researchers have made a significant advancement in the synthesis of β-lactam scaffolds, structural components frequently found in essential antibiotics. The breakthrough uses nickel catalysts to overcome challenges in β-lactam synthesis, enabling more efficient and simplified production of high-value materials.
A research team at USTC realized single-pixel imaging of single living cells using 3D light-field illumination, achieving a resolution of up to 2.7 μm laterally and 37 μm axially. This breakthrough enables volumetric imaging of microscopic objects with high-performance 3D SPI.
Researchers found that phytosterols can reverse age-related hearing loss in mice by replenishing cholesterol in sensory cells. The study suggests that these plant-based compounds could be a convenient way to combat age-related hearing loss.
Researchers from Mount Sinai found that Asian Americans have a significantly high exposure to PFAS, with median exposure scores 89% higher than non-Hispanic whites. The study used advanced data science methods to account for complex exposure sources and heterogeneity across different groups.
A team of KAUST researchers has found a critical protein that regulates cell division and proliferation in breast cancer and leukemia. Their work clears the way for the development of targeted drugs by refuting recent challenges to their approach.
Four out of five emperor penguin colonies in the Bellingshausen Sea experienced complete breeding failure in 2022 due to unprecedented Antarctic sea ice loss. The study suggests that climate change is directly impacting Emperor penguin populations, leading to reproductive failures.
Researchers at the University of Münster develop a novel concept to regulate reactivity and selectivity in chemical reactions using light as an external energy source. The aluminum complex catalyst enables the selective conversion of chiral molecules into a single form, improving spatial control in organic chemistry.
A new analysis reveals that emission reductions from REDD+ programs have been overestimated, with most projects failing to significantly reduce deforestation. The study found that only a subset of projects have made substantial contributions to climate change mitigation, and many more credits are available than their actual value.
A team of researchers from Boston College has observed electronic nematic order as a stand-alone phase in a titanium-based Kagome metal. The study revealed the presence of electronic unidirectionality without charge density waves, which challenges current understanding of this phenomenon.
A new US Securities and Exchange Commission proposal could unveil substantial corporate carbon damages due to varying industrial compositions across countries. The top four industries account for 89% of global damages, with energy-intensive sectors contributing the most.
A new global biodiversity observing system (GBIOS) is proposed to combine technology, data, and knowledge from around the world to monitor biodiversity change and target conservation action. The system can provide the information needed at the pace required to support countries in achieving their biodiversity goals.
Researchers from the Center for Regenerative Medicine at Boston University School of Medicine have discovered a novel approach for engrafting engineered cells into injured lung tissue. They successfully reconstituted the stem cell compartment of injured airways and alveoli using cells engineered from pluripotent stem cells, resulting i...
Researchers at MIT developed a method to simplify the process of whole-body manipulation for robots, enabling them to reason efficiently about moving objects. The technique uses AI and smoothing to reduce the number of decisions required, making it possible for robots to adapt quickly in complex environments.
A new study uses nonlinear partial differential equations to model the transportation of hydrogen-heterogeneous mixtures through pipeline systems, ensuring predictable operations. The research proposes injecting hydrogen gradually into existing natural gas pipelines to maximize their utility in reducing carbon-emitting fossil fuels.
Researchers find catastrophic breeding failure for emperor penguins due to Antarctic sea ice loss. The study indicates that over 90% of emperor penguin colonies will be quasi-extinct by the end of this century, based on current global warming trends.
Research finds that adolescents of color with a disability experience more racial discrimination compared to peers without SHCNs. This study aims to raise awareness among healthcare providers about recognizing and navigating racial discrimination, particularly for children of color with special health care needs.
A new study led by Dr. Xuekun Lu has found a way to prevent lithium plating in electric vehicle batteries, which could lead to faster charging times and improve the battery's energy density. The research also reveals that refining the microstructure of the graphite electrode can minimize the risk of lithium plating.
The DecodeME study reveals that women are more severely affected by ME/CFS, experiencing more symptoms and co-occurring conditions than men. The study confirms a sex bias among ME/CFS patients, with women making up 83.5% of respondents.
Scientists identify three distinct serotypes of SARS-related coronaviruses, suggesting broad-spectrum vaccines necessary for effective immunity against future variants. The study found that pre-existing immunity is insufficient to prevent current and future infections.
Researchers identified midnolin as a protein that degrades short-lived nuclear proteins by directly grabbing them and pulling them into the proteasome. This mechanism is crucial for genes related to brain function, immune system, and development.
Researchers developed an AI-powered system to evaluate cognitive abilities automatically, utilizing acoustic and linguistic features in speech. The system showed superior performance in predicting dysarthria severity in individuals with Wilson Disease.
A recent study found that the FDA approved 65% of novel drugs in 2022 based on a single clinical trial, while only half of the available studies were classified as randomized clinical trials. This lack of transparency raises concerns about the completeness of the approval process and patient access to accurate information.
Researchers developed a photoresponsive carbon-encapsulated magnetite nanodonut nanoenzyme with dual catalytic activity for synergistic cancer therapy. The nanoenzyme showed improved stability, biocompatibility, and therapeutic ability due to its quasi-two-dimensional structure.
A new pocket-sized device uses heat signatures and bacterial fluorescence to identify infected wounds, providing a more accurate diagnosis than traditional methods. The device achieved an overall accuracy of 74% in identifying different categories of wounds, with 100% accuracy in distinguishing between infected and non-infected wounds.
New study finds that up to 67% of future hydropower plants in Africa may not be worth the investment due to economic competition with solar and wind power. However, some new hydropower plants could still provide cheap power in the short-term and help integrate solar and wind energy.
A pioneering drug for a rare kidney disease, eculizumab, has been found to prevent 86% of patients from going into kidney failure. This breakthrough treatment is highly effective and improves patient outcomes without the need for dialysis or transplant.
Researchers found long-lasting PFAS in 27 out of 39 paper straws tested, with bamboo straws also contaminated. The study highlights the potential harm of seemingly eco-friendly alternatives to plastic drinking straws.
A new gene-editing technique combines peptide nucleic acids and prokaryotic Argonautes to introduce targeted breaks in the genome. The approach, called PNP editing, offers advantages over CRISPR-based methods, including improved specificity and targeting.
A study by researchers at the University of Minnesota Medical School found that high costs for hepatic encephalopathy treatment are associated with decreased treatment retention among patients. Patients who are younger and have metastatic cancer or depression are more likely to skip their medication.
Researchers at the Centre for Genomic Regulation have discovered how proteins work together to regulate treadmilling, a critical mechanism in cell division. The discovery highlights the importance of protein KIF2A and its role in maintaining tension between chromosomes during cell division.
Researchers investigating early liver transplantation for alcohol-associated liver disease aim to understand who benefits most and develop best practices. They will collect data on patient outcomes, biological samples, and audio recordings to identify factors influencing selection decisions.
Researchers have engineered an AAV vector to target brain vascular pericytes and smooth muscle cells, potentially treating conditions like Alzheimer's disease and Parkinson's. This breakthrough could revolutionize gene therapy by delivering genes directly to the brain's blood vessels.
A new study by the University of South Australia finds that mothers are experiencing a relentless mental load linked to their children's digital use, impacting their physical and mental health. This 'digital care work' requires mothers to monitor and manage their kids' media use, adding an extra layer of complexity to modern mothering.
A study of 24,000 hospitalized COVID-19 patients found that pulse oximetry led to delayed treatment and higher readmission rates, with racial disparities observed among black patients. The study highlights the importance of accurate oxygen saturation monitoring in preventing these outcomes.
A study published in Science of the Total Environment found that biofiltration increased coho salmon hatchling survival by up to 87%, reducing mortality from stormwater runoff exposure. The method effectively removes contaminants, but implementation faces hurdles due to land requirements.
Research finds that community-based adult day services can reduce the risk of frailty among older adults by 40%, while home-based personal assistance services have no significant effect. This study suggests that active community engagement may help maintain independence and prevent frailty in older adults.
Researchers at the University of Manchester are enhancing bioprinting technology to create new skin, bone, and tissue for transplantation in space. The project aims to protect astronauts' health from diseases like osteoporosis caused by microgravity exposure.
Researchers have discovered a novel nursery pollination system in which fungi-eating orchids and fruit flies engage in mutualistic symbiosis. The study found that the orchids offer their flowers to the flies in exchange for pollination, providing a breeding ground for the flies' larvae.
A study published in Pediatrics found that texting can increase participation in public health programs, with 99% of staff having a valid cell phone number and fewer than 4% opting out. The SCALE-UP Counts program showed that texting can reach staff in K-12 schools to provide health screening messages.
A large population study found that unhealthy lifestyles between ages of 60 and 64 are associated with a doubling in the risk of nursing home admission. Physical inactivity, smoking, poor diet, and sleep disorders were linked to an increased risk of care, particularly among 60-64 year olds.
A neglected brain region has been identified as a key player in addiction recovery. The supplementary motor cortex was found to be hyperexcitable in individuals with cocaine use disorders, even after withdrawal periods of 45 days. This discovery may lead to new treatment approaches using transcranial magnetic stimulation.
Research led by Vesna D. Garovic reveals that pre-eclampsia causes accelerated aging in women, leading to increased risks of cardiovascular and kidney disease. Women with a history of pre-eclampsia are more likely to develop chronic conditions at a younger age.
Experts from the Aging Biomarker Consortium propose a framework of biomarkers for brain aging, aiming to assess brain health and prevent age-related diseases. The consensus statement identifies key biomarkers reflecting 'real age', brain structure, and function.
A study by University of California - Davis researchers found that blending certain ingredients in smoothies can influence nutritional absorption. Adding a banana to a blueberry smoothie decreased the level of flavanols in the body, with participants having 84% lower levels compared to those who consumed a flavanol capsule.
The NIMS-OS middleware coordinates materials-search AI and robotic experiment systems for efficient automation. The system successfully executed a model experiment to identify effective electrolytes for lithium metal electrodes.
A team of researchers from Dalian Institute of Chemical Physics has developed a microbial platform for efficient lignocellulose bio-refinery in yeast. The system can produce valuable chemicals like fatty acids and 3-hydroxypropionic acid, overcoming limitations in xylose assimilation and glucose repression.