Scientists at Nanyang Technological University have developed a sustainable method to produce lactic acid using discarded jackfruit seeds. The new process is cheaper and more efficient, reducing waste and environmental impact while addressing rising production costs.
Researchers from Max Planck Institute identified mechanisms of deubiquitinating enzymes acting as Fubi proteases, regulating ribosomal protein maturation and modulating immune responses. This discovery expands understanding of post-translational modification systems and their roles in cellular processes.
The study, led by Professor José Manuel Guerra, reveals that gilt-head sea bream farmed in estuaries exhibit similarities to wild populations, with a rich diet and low heavy metal concentrations. This finding highlights the potential of estuaries as a sustainable aquaculture site.
A new study in mice shows that consuming emulsifiers during pregnancy or lactation is associated with mild health risks for offspring. The researchers found that the offspring of mice that consumed emulsifiers had a greater risk of certain health issues, including metabolic, cognitive, and psychological impairments.
Researchers discovered a correlation between Zener relaxation and magnetostriction in FeGa single crystals, revealing that stress-induced reorientation of defects can give rise to an internal friction peak. The study also found a positive correlation between Zener relaxation strength and the magnetostriction coefficient, demonstrating ...
Researchers analyzed tree-ring data and historical records to reconstruct rainfall totals in the eastern Amazon. They found that recent extreme floods may not have exceeded natural hydroclimatic variability, but could still pose devastating consequences for a growing population living in high-risk areas.
A study at the University of Gothenburg found that preterm babies given a supplement with omega-3 and omega-6 fatty acids had improved visual function by age 2.5. The supplement also seemed to improve the brain's ability to interpret visual impressions.
Researchers found that urine levels of adenine are predictive and causative biomarkers of looming progressive kidney failure in patients with diabetes. An oral therapeutic drug showed promise in mice by reducing kidney adenine levels and protecting against diabetic kidney disease.
A study published in Science found that overestimations of forest preservation in voluntary REDD+ projects result in the generation of millions of worthless carbon credits. The research team calculated that only 6% of these credits are linked to actual reductions in carbon emissions.
Researchers found that specific regions of the genome with unique features act as hotspots for mutation accumulation in human cancer. Certain mutational signatures linked to alcohol consumption accumulate in early-replicated genome segments, defying conventional understanding.
A global team of scientists has identified 39 genetic mutations associated with heart failure and pinpointed seven druggable proteins that may prevent its onset. The findings could help physicians identify and treat at-risk patients before heart failure occurs.
Researchers found that inducing inflammation triggers an epigenetic response in Tas2r genes, leading to a decrease in sweet taste preference and potentially affecting appetite and medication tolerance. This study has significant clinical implications for understanding behavioral aspects of illness and developing effective bitter blockers.
Researchers at the University of Surrey are developing thermo-active road solutions that could reduce carbon emissions and improve road safety. The new technology uses geothermal energy to regulate road surface temperatures, reducing damage from extreme weather.
A new study by the University of Illinois and USDA-Agricultural Research Service has identified the key factors influencing sweet corn yield. The analysis found that seed source is a significant variable, with processors having a choice over which hybrids to use, and high nighttime temperatures also impact yield.
Researchers found that severe COVID-19 survivors exhibit elevated muscle sympathetic nerve activity in response to mental stress, which accelerates heartbeat and increases blood pressure. This exaggerated reaction, combined with impaired vasodilation, poses a significant risk for cardiovascular complications.
A novel algorithm called MWO-BOSS was proposed to efficiently select variables in high-dimensional spectral data. The algorithm combines six weight vectors and uses a threshold search strategy to improve model predictive ability.
Researchers at the University of Illinois Chicago have discovered that trained immune cells can remove cellular debris and reduce inflammation in the lungs. This 'memory' or training allows these cells to respond better to subsequent infections, potentially leading to a cell therapy to prevent acute lung injury.
Researchers found 27 million cubic meters of sediment moved through Houston waterways, equivalent to 40% of the Mississippi River's annual discharge. The study suggests river straightening can exacerbate sediment bypass, decreasing reservoir holding capacities by up to 1.6%
Research suggests that certain gut problems, such as gastroparesis, dysphagia, and irritable bowel syndrome (IBS), may precede the development of Parkinson's disease. A nationwide medical record network study found a significant association between these conditions and an increased risk of Parkinson's diagnosis.
A new device called frequency-modulated Faraday rotation (FM-FRS) spectrometer was developed for rapid detection of hydroxyl radicals. The device achieved a detection limit of 6.8×10^8 molecules/cm³ with high precision and selectivity.
Researchers have developed MN-predict, a platform that identifies individuals at high risk of acute myeloid leukemia and related cancers. The test requires a blood sample and can be used to design new treatments and prevent the development of these cancers.
A new study finds that integrating longitudinal tobacco cessation care into lung cancer screening improves quit rates and enhances the benefits of screenings. Researchers recommend incorporating behavioral treatment and medication into the screening process to help smokers quit.
Researchers found that mutations in blood stem cells can promote the development of colitis-associated colon cancer (CAC) by increasing blood vessel formation. Blocking certain drugs, such as axitinib, inhibited CAC tumor growth in mice with clonal hematopoiesis, suggesting potential therapeutic strategies.
A new study found that voluntary collective isolation alone was ineffective in preventing the spread of COVID-19 among the Amazonian Tsimané. The researchers used a computer model and serological testing to confirm their predictions, showing nearly identical infection rates across communities.
The 3D-BRICKS project aims to develop a new family of 3D nanotransistors using DNA technologies, reducing production costs and increasing computing power. By leveraging carbon nanotubes and self-assembling materials, researchers hope to create compact and efficient nano-transistors.
A new study has discovered hundreds of mummified bees from the time of Pharaoh Siamun, which have provided valuable insights into the decline of bee populations. The bees were found in a fossilized state on the southwest coast of Portugal and preserved the smallest anatomical details, including sex and pollen supply.
A new fund to fast-track patient access to potentially valuable new medicines may incentivise the pharmaceutical industry to develop high-priced drugs for rare diseases with weak clinical evidence. The NHS England Innovative Medicines Fund risks disincentivising the generation of essential evidence if not implemented appropriately.
A four-wave cohort study followed 800 children from age 10-16 to examine correlations between social media use and symptoms of anxiety and depression. The results showed no causal link, regardless of whether children used social media for self-expression or social interaction.
Cattle farming expansion and unchecked climate change would expose over 1 billion cows to heat stress, impacting animal welfare and farm income. Cutting carbon emissions rapidly can reduce these impacts by 50-84%, protecting cattle in some regions.
Scientists developed a novel technique to evaluate carbon particle dispersion in battery electrode slurries, enabling enhanced battery electrodes. The study's results show that measuring viscosity and electrochemical impedance can provide insights into dispersibility.
A CRISPR-Cas3 system has restored dystrophin protein function in induced pluripotent stem cells from patients with Duchenne muscular dystrophy. The approach uses a dual CRISPR RNA method to remove large sections of the dystrophin gene, yielding truncated but still functional proteins for various mutation patterns.
Scientists at Van Andel Institute have discovered processes that enable the brain to adapt to damage in movement, cognition, and sensory perception circuits. This finding may help optimize current treatments or develop new ones that repair or bypass broken circuits.
Researchers from Brigham and Women's Hospital evaluated ChatGPT's recommendations for cancer treatment aligned with National Comprehensive Cancer Network (NCCN) guidelines. They found that approximately one-third of the chatbot's responses were non-concordant, highlighting its limitations in clinical decision-making.
Researchers have discovered numerous small-scale 'picoflare' jets within a coronal hole, which could supply energy and plasma to the solar wind. These widespread yet faint jets are powered by magnetic reconnection and appear to be a key component of space weather within the heliosphere.
The CABINET trial showed statistically significant and clinically meaningful improvements in progression-free survival for patients with pancreatic and extra-pancreatic neuroendocrine tumors. The study also demonstrated a consistent safety profile for cabozantinib, with no new safety signals identified.
A new study published in the Journal of Vascular Access found that subcutaneous anchors are more effective than adhesive securement devices in preventing catheter dislodgement. The study showed a significant reduction in unplanned catheter replacements and complications, with SecurAcath demonstrating a 99% success rate.
A study published in Scientific Reports found that ChatGPT achieved similar or higher average grades than university students in 9 of 32 courses, with notable strengths in 'Introduction to Public Policy'. The survey also revealed that 74% of students would use ChatGPT for assignments, while educators underestimated this trend
Researchers created highly crystalline All graphene macrostructures with micro-to-macro scalable electrical properties using a novel covalent growth technique. The approach achieved a 100-fold increase in cross-layer conductivity compared to non-covalent assembly methods.
Researchers found pronounced growth spurts in both body weight and length in bonobos, mirroring patterns seen in humans. The study's scale-corrected approach revealed similar hormone surges and corresponding growth curves in both species, highlighting a potential evolutionary connection.
The South Carolina Clinical and Translational Research Institute's program provides early-career clinicians with the time and training needed to establish a sustainable portfolio of clinical trials. Scholars attend 'meet the expert' presentations, discuss strategies with mentors, and select suitable trials.
A new study found that increased paternal involvement in childcare is associated with lower risk of developmental delay and promotes young children's development by reducing maternal parenting stress. High levels of paternal engagement yield advantages for both children and mothers.
Researchers at the University of Texas Medical Branch have identified a possible treatment for Lassa fever, a highly infectious and often fatal disease. A new monoclonal antibody cocktail, Arevirumab-3, was shown to successfully treat cynomolgus monkeys infected with the virus in advanced stages.
Researchers investigated SARS-CoV-2 responses in 222 donors from Central Africa, Europe and East Asia. They found disparities in immune responses due to blood cell composition, latent cytomegalovirus infection and human genetic factors. These population differences may help improve patient management in future epidemics.
HSE biologists explain how coronavirus evolves from Wuhan variant to Omicron, highlighting the crucial role of microRNA molecules in the process. The study found that substitutions in the viral genome disrupted microRNA binding regions, leading to the emergence of more contagious and resilient strains.
A new approach to quantum light emitters generates circularly polarized single photons, a crucial step towards quantum cryptography and information processing. The innovation uses a proximity-effect approach to produce low-cost fabrication and reliability.
Researchers have identified an essential stage in the takeover of rice cells by a fungus, which could accelerate treatment or prevention of rice blast disease. The discovery involves a modification in tRNA molecules that aid in protein construction, and its absence leads to reduced virulence.
Researchers have developed a new material that can transform flat surfaces into complex, curved structures using plant-inspired pneumatic cells. The system, inspired by the shape-memory properties of certain leaves, allows for dynamic morphing without compromising mechanical stability.
A new framework, SHARC, provides a way for shore-based scientists, citizen scientists, and the public to collaborate with robotic sampling processes. The framework enables remote participants to conduct shipboard operations and control robotic manipulators using basic internet connection and consumer-grade hardware.
Researchers from Zhejiang University have discovered that Polygonatum sibiricum contains a significant amount of fructo-oligosaccharides, approximately 30% of the dry rhizome. These prebiotics promote gut health by fostering beneficial bacteria growth.
Researchers use surface normal nonlinear photodetector to improve speed and energy efficiency of diffractive optical neural networks. The new device can perform high-speed image and video processing at the speed of light in an extremely energy efficient manner.
Scientists at NTU Singapore have developed a flexible, human cornea-thin battery that can store electricity from saline solution. The battery could power smart contact lenses with displays and augmented reality capabilities.
Researchers at UCLA have found that embedding study recruitment in pre-appointment check-in pages can increase participation rates up to 40 times higher than traditional methods. The new technique, called preCheck-in recruitment, resulted in a socio-demographically representative patient population without financial incentives or staff...
Researchers found AI chatbot responses to top cancer queries are generally accurate but lack actionable information. These limitations suggest relying on chatbots for supplementary purposes rather than primary medical information.
A new methodology, developed by USGS researchers, integrates earthquake-induced ground failures with ground shaking hazards to provide a comprehensive forecast for pipeline damage. This approach is crucial for identifying potential damage in buried gas pipelines covering hundreds of kilometers.
The study aims to evaluate the efficacy of a synbiotic medical food, SBD111, in maintaining lumbar spine bone mineral density with aging. The researchers hope to provide new dietary interventions for preventing osteoporosis and fractures.
A new study suggests that one branch of plant immunity evolved early during terrestrial evolution, enabling plants to establish themselves on dry land. The research found that pattern-triggered immunity (PTI) is conserved in non-vascular plants, such as liverwort Marchantia polymorpha.
Researchers at Weill Cornell Medicine discovered a new relationship between cancer cells and the immune system, showing how prolonged activation of the STING pathway leads to cellular signaling changes that aid cancer's spread. This finding explains why drugs activating STING have been unsuccessful in clinical trials.
A research team at Ritsumeikan University has identified the elusive ApiT gene in celery, crucial for apiin synthesis. The discovery may pave the way for efficient biosynthesis of apiin, a compound with potential health benefits and medicinal uses.
A graduate student's accidental discovery sheds light on how squash bug nymphs acquire essential bacteria. Researchers found that the nymphs eat adult feces to obtain the necessary microbes, an elegant solution to a basic problem. This finding may offer insights for improved methods to control squash bugs, a significant agricultural pest.
Researchers at EPFL have developed the Backtracking Dynamical Cavity Method (BDCM) to study disordered systems, which are found in materials science, climate, and social networks. By tracing steps backward from stable points, the BDCM provides valuable insights into complex system dynamics.