A recent study led by UCLA researchers has identified a potential new strategy for treating glioblastoma by targeting a specific metabolic process in cancer cells. The study found that disrupting this process could make glioblastoma cells more vulnerable to cell death, offering hope for new treatment options.
A recent study has identified the specific gut bacteria that pose a threat to neonatal babies, particularly those with necrotising enterocolitis. Researchers analyzed genomic similarities in Clostridium perfringens and found a set of strains with lower disease-causing capacity, lacking genes responsible for toxin production.
Researchers analyzed a comprehensive dataset from Catholic parish records and genotype data to reveal how local topographies influenced French Canadian relatedness. They found that geographic features, particularly river networks, shaped Quebec's population structure and contributed significantly to the French Canadian gene pool.
The metaverse has the potential to make scientists more effective by removing barriers, improving teaching and learning, and enabling new experimental environments. Researchers must also plan well and avoid potential pitfalls, such as ownership and privacy issues.
Researchers designed and tested textile fibers that can change shape and generate force like a muscle, showing promise for use as cell scaffolds. The findings suggest the fibers could be used to develop 3D models of living, moving systems in the human body.
UMC Utrecht researchers are conducting two new projects to treat cancer using image-guided interventions. One project uses MRI-guided radiotherapy for locally advanced pancreatic cancer, while the other employs ultrasound techniques for head and neck cancers.
Researchers have identified a novel model and therapy to mitigate the development of REM sleep behavior disorder, which affects over 3 million Americans. Dual orexin receptor antagonists have been shown to significantly reduce dream enactment behaviors, providing a promising new treatment option.
A study suggests that iron-rich particles from meteors and volcanic eruptions could have generated precursors for organic molecules needed for life. The researchers found that these particles promoted the conversion of carbon dioxide into hydrocarbons and other compounds under various conditions.
A new study published in the Journal of the American College of Surgeons predicts a significant increase in cancer cases due to COVID-19 screening delays, with lung, breast, and colorectal cancers most affected. The study found that missed diagnoses during the pandemic may lead to delays in treatment and upstaging of disease.
The US has lost 57.6 billion tons of topsoil due to farming practices, but new research suggests no-till methods can drastically reduce erosion and extend fertility for centuries. No-till farming, currently practiced on 40% of Midwest cropland acres, can modelled to slow down soil loss.
Researchers discovered that knapping is far more dangerous than previously understood, with severe injuries including bone piercings, tourniquet needed ankles, and eye damage. Injuries varied across body parts, including hands, feet, legs, and torso.
Researchers at Penn State discovered that coal can act as a geological hydrogen battery, storing hydrogen for future use. The team found that coal's unique structure and properties make it an ideal material for hydrogen storage, with low-volatile bituminous coal performing best in tests.
Researchers at the Center for One Health Research have found that antiviral drugs can make antifungals work again by blocking efflux pumps in Candida auris. This approach may be a key treatment strategy against the deadly fungal pathogen, which has a 60% mortality rate.
Researchers identified genes for virulence and antimicrobial resistance in two bacteria that co-occur with C. difficile, posing a threat to human health. The study provides new insights into the development of antimicrobial resistance and offers potential treatment strategies.
New research from Ohio State University suggests that cognitive dissonance can lead to added pressure on the neck and low back during lifting and lowering tasks. The study found that participants who experienced higher levels of cognitive dissonance had increased spine loading, particularly in the neck region.
A study published by the American Psychological Association found that teen girls who experience greater interpersonal stress and have difficulty solving interpersonal problems are at a higher risk of suicidal behavior. The research suggests that problem-solving deficits under distress may contribute to this link.
A new study published in JAMA estimates the total economic burden of racial and ethnic health inequities in the US to be over $450 billion in 2018. The study also details costs of racial and education-related health inequities for each state, highlighting disparities among different racial and ethnic groups.
Children with superior motor skills outperform peers in reading and mathematics by the end of third grade. Early diverse movement supports motor development, but physical activity doesn't predict academic or motor skill success. Dr. Eero Haapala's study highlights the importance of motor skills as an academic booster.
A nationwide study of nearly 10,000 adults identifies 12 hallmarks of long COVID, including debilitating fatigue, loss of smell or taste, and gastrointestinal symptoms. The findings provide a new scoring system for clinicians to define and investigate treatments for patients with long COVID.
University students' tweets showed a positive correlation between social events and hobbies with subjective well-being, while politics had a negative effect. Negative expressions also increased during the pandemic, negatively impacting students' desire for self-presentation and overall well-being.
Researchers have developed an unsupervised learning-based optical fiber imaging system that can recover high-fidelity images from degraded or scrambled speckle patterns without paired labeling. The system, named Restore-CycleGAN-GALOF, achieves nearly artifact-free and robust full-color image transport through a meter-long optical fibe...
Researchers found specific HLA molecules linked to MPO-AAV susceptibility and increased risk of relapse, potentially leading to precision medicine solutions for treatment. Biomarkers may be developed to predict relapse risk, improving patient outcomes.
A new technique developed by researchers at the University of Warsaw's Faculty of Physics allows for up to a 200-fold change in pulse duration with an efficiency of 25 percent. This enables quantum Internet links to operate up to 50 times faster, contributing to the development of superfast quantum connections.
New research reveals that over 300 weevil species have intertwined relationships with specific plants, pollinating and relying on them for food and breeding sites. This unique interaction highlights the importance of weevils as unsung heroes in maintaining ecosystems and products like peanut butter and Nutella.
As Arctic warms, female arctic ground squirrels emerge from hibernation 10 days before males, disrupting reproductive rates and altering mortality rates. This phenological mismatch could have large ecological impacts on Arctic food webs.
Researchers detect two planets, super-Earths and mini-Neptunes, in a synchronized dance around a cool star. The system's unique configuration could help explain the formation mechanism of these mysterious planetary types.
Researchers at LMU identify curcumin as a potential treatment for colon cancer by activating the miR-34 pathway, which induces premature aging and programmed cell death. The substance also makes tumor cells more sensitive to chemotherapy.
Researchers find that free 19S particles, separate from the proteasome complex, regulate synaptic proteins and adapt to new functions in response to changing circumstances. This discovery provides a new target for treating neurological diseases such as Parkinson's disease and dementia.
Researchers developed a fully knitted, circuit-embedded knee wearable for wireless sensing of joint motion in real-time. The wearable overcomes limitations of typical wearable sensors by using a single fabric with high stretchability and sensitivity.
A multidisciplinary team led by Hong Chen successfully induced a torpor-like state in mice using ultrasound, which also worked on rats. The researchers found that stimulating the hypothalamus preoptic area with ultrasound activated neurons and induced changes in body temperature and metabolism, allowing for the preservation of energy.
Researchers identified 37 symptoms across multiple pathophysiological domains that are more common in SARS-CoV-2 infected participants at six months post-infection. A preliminary rule for identifying postacute sequelae of SARS-CoV-2 infection (Long COVID) was derived from a composite symptom score and requires further refinement.
Dr. Kristin Rojas addresses quality of life concerns for breast cancer patients undergoing endocrine therapy, including sexual health, fertility preservation, and bone health. Her program, Music, has become a model for similar programs across the US, improving patient adherence to treatment.
A deep learning system accurately classifies autism spectrum disorder and predicts symptom severity based on behavioral responses to social cues. The method offers a digital measurement of joint attention, but further validation is needed.
A clinical trial found that a telephone-based weight loss program can help breast cancer patients with overweight or obesity lower their weight by a significant degree. Women who received the program lost an average of 4.8% of their baseline body weight, compared to a 0.9% increase in the control group.
The Phase 1/2a study found that FORE8394 had low-grade adverse events and was effective against V600 and non-V600 BRAF mutant tumors. The drug targets a previously under-treated population by thwarting cancer cells' ability to escape BRAF inhibition.
The Alzheimer's disease development pipeline has seen an increase in promising therapies and pharma investment, driving momentum in clinical trials. The pipeline currently has 187 clinical trials, with recent FDA approvals for two disease-modifying therapies, and more on the way.
Researchers analyzed hospitalization and fatality rates of SARS-CoV-2 infection in England between May 2020 and March 2022. The study found that the mass vaccination campaign significantly reduced severe effects of the virus, with notable improvements after the emergence of Alpha, Delta, and Omicron variants.
The Voting Rights Act of 1965 enfranchised a new section of society in the US South, resulting in increased Black turnout and election of Black politicians. Studies found that the act promoted tangible improvements in policy changes, including increased spending on public infrastructure.
The University of Virginia Health System has developed a plan to improve the use of electronic health records, reduce clinician workload, and enhance patient care. The plan outlines three 'essential' steps for improving electronic health reforms, including implementing unique personal safety identifiers to streamline operations.
A study published in PLOS Biology found that polar fish reproduce later and produce more eggs than tropical fish, confirming model predictions. As a result, polar fishes tend to produce more eggs than tropical fishes.
A new study by Anglia Ruskin University found that people with sight loss in the UK are confused by a 'disjointed' certification system, creating barriers to accessing support and benefits. The research highlights inconsistencies in the process, long waiting lists, and lack of clarity around entitlements.
The Chinmo gene plays a crucial role in establishing the juvenile stage in insects, promoting tissue growth during this stage. The study also reveals that the Chinmo, Br-C, and E93 genes coordinate the formation of adult organs through sequential action, which may hold key to understanding cancer processes.
Researchers at the Beckman Institute for Advanced Science and Technology have developed a new framework for super-resolution ultrasound using deep learning, reducing processing speeds from minutes to seconds. The new technology enables real-time blood flow visualization, overcoming challenges faced by conventional methods.
Researchers at UTHealth Houston are investigating the role of fibrin and fibrinogen in traumatic brain injury and hemorrhagic shock. The four-year grant will fund Phase II of a stem cell clinical trial evaluating whether mesenchymal stem cells reduce chronic neuroinflammatory response to traumatic brain injury.
Anita McGahan, a professor at the University of Toronto's Rotman School, has been recognized for her outstanding service to the field of strategic management. She will receive the William D. Guth Distinguished Service Award at the Academy of Management's annual meeting in August.
Scientists at McMaster University and MIT have used AI to discover a new antibiotic targeting Acinetobacter baumannii, a deadly drug-resistant pathogen. The new antibiotic, abaucin, targets only A. baumannii, reducing the risk of rapid resistance development.
A combination of microneedling and cupping therapies has been found to significantly improve skin thickness and increase collagen levels in a study published in Plastic and Reconstructive Surgery. The experimental study examined the effects of adding cupping therapy to microneedling on skin regeneration and scar healing.
A deep learning-based framework called EMGSense enables accurate wearable EMG device usage through AI self-training techniques. It achieves average accuracy of 91.9% in gesture recognition and 81.2% in activity recognition, outperforming state-of-the-art approaches.
Researchers developed a mobile application to detect Alzheimer's and mild cognitive impairment from speech data. The app achieved high accuracy rates, demonstrating its potential as an early detection tool.
A new study suggests expanding the search for habitable planets to consider the space between a star and the soot line in planet-forming disks, which could lead to discovering worlds with rich organic carbon and poor water content. This new model proposes that such planets may have more carbon than Earth and potentially harbor life.
Researchers discovered that melanoma skin cancer cells adopt an efficient style of movement called rounded-amoeboid migration, which requires less energy than traditional cell movement. This process involves reshaping mitochondria to operate in a low-power mode, allowing cells to survive in stressful environments.
Researchers found altered serotonin 2A/C receptor binding in brain stems of infants who died from SIDS, suggesting a biological basis for the condition. The study suggests that specific combinations of genetic vulnerability, external stressors, and critical developmental periods may contribute to SIDS.
Researchers have characterized the excitation energy of thorium-229 with great precision, a crucial step towards creating the first nuclear clock. The nuclear clock would register forces inside the atomic nucleus, enabling scientists to delve deeper into fundamental physical phenomena.
Researchers from Carnegie Mellon University have created a fabric and sensing system, RobotSweater, that allows machines to better interact with humans. The knitted textile 'skin' can sense contact and pressure, enabling robots to move in response to human gestures.
A University of Maryland study found that walking strengthened brain connectivity and improved memory in older adults with normal brain function and those diagnosed with mild cognitive impairment. The research adds to the growing evidence that exercise slows cognitive decline and may delay Alzheimer's disease.
Soil microbiota from stressful environments can enhance tree tolerance to drought, heat, and cold. Diverse microbial communities promote plant resistance to climate stress through various mechanisms.
Researchers investigate structure-activity correlation for CO2 electrolysis in SOECs, revealing dynamic reconstruction of active sites. The study highlights the role of IrFe alloy nanoparticles on improving CO2 conversion performance.
China experienced its warmest year on record in 2022, with extreme heatwaves and droughts affecting the country. The report highlights a dry climate with low precipitation levels, resulting in severe weather events such as flooding and sandstorms.
Researchers found that female arctic ground squirrels are emerging from hibernation earlier every year due to warmer temperatures, potentially leading to healthier litters and higher survival rates. This change is accompanied by differences in male hibernation patterns, which may have negative consequences for the food web.
A team of scientists has developed an automated algorithm to reconstruct the shape of each neuron inside a light microscopy image using deep learning. This breakthrough addresses the challenge of generalizing algorithms across diverse species, brain locations, developmental stages, and microscopy image sets.