About The Study: In this analysis of data from 9,764 participants in the RECOVER adult cohort, a prospective longitudinal cohort study, 37 symptoms across multiple pathophysiological domains were identified as present more often in SARS-CoV-2–infected participants at six months or more after infection compared with uninfected participants. A preliminary rule for identifying postacute sequelae of SARS-CoV-2 infection (PASC), also known as long COVID, was derived based on a composite symptom score. As a first step to providing a framework for other investigations, iterative refinement that further incorporates other clinical features is needed to support actionable definitions of PASC.
Authors: Andrea S. Foulkes, Sc.D., of Massachusetts General Hospital in Boston, is the corresponding author.
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(doi:10.1001/jama.2023.8823)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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