Researchers propose a 'state space' approach to reframe farming planning questions, enabling analytics and machine learning to explore optimal crop combinations and simulate different scenarios. This framework allows farmers to design diverse agricultural landscapes based on natural ecosystems, increasing crop yield and sustainability.
The COVID-19 pandemic had a significant impact on cancer care, with variances in new diagnoses and disrupted care reported in the National Cancer Database. The study highlights the need for future research to understand the lasting effects of the pandemic on chronic diseases such as cancer.
A recent review of China's ecological restoration efforts highlights the progress made in protecting and restoring key ecosystems. The research proposes a co-evolutionary framework to describe landscape-scale ecological restoration and its impact on ecosystem services, sustainable livelihoods, and socioeconomic development. Key finding...
Researchers at Leipzig University have increased the efficiency of an enzyme that breaks down PET plastic, which has implications for bioplastics and a more sustainable future. The team used computer simulations and experiments to improve the enzyme's activity and stability.
A new study reveals that dairy was a key component of early human diets on the Tibetan Plateau, consumed by diverse populations including females and males. Dairying supported prehistoric occupation of the highland region, allowing humans to thrive in extreme environments.
Researchers developed an electrochemical sensor using 3D printing to detect Parkinson's disease at different stages by measuring levels of the protein PARK7/DJ-1. The sensor was miniaturized for portability and could be used for continual monitoring with alerts for physicians and patients.
Researchers found that black and turkey vultures ingest more plastic in landscapes with more developed landcover and higher densities of commercial food providers. They may eat plastic thinking it's nutritious bone fragments or intentionally to collect bulk for vomiting up indigestible parts of carrion.
A recent study found that food processing facilities and high-rise apartments with 10 stories or higher are major contributors to nitrogen dioxide emissions in California. The research, published in Science of the Total Environment, used satellite remote sensing data to analyze NO2 emissions from various property types.
Researchers found that patients with two or three separate areas of breast cancer in the same breast can opt for lumpectomies followed by whole-breast radiation therapy instead of mastectomies, resulting in better patient satisfaction and cosmetic outcomes. The study also showed that preoperative MRI scans reduced local recurrence rates.
Researchers found that TaMADS29 interacts with TaNF-YB1 to regulate early grain development in bread wheat. The complex helps prevent excessive ROS accumulation, promotes nutrient transport into the endosperm, and allows normal grain filling.
A recent study found that most retail cannabis products in Colorado have lower THC levels than reported on the label, affecting up to 70% of tested samples. The discrepancy may be due to various factors, including production methods and testing protocols.
A recent study found that the way volcanic eruptions are represented in climate models can degrade their accuracy in predicting decadal variations in sea surface temperatures in the tropical Pacific. These variations have significant impacts on global precipitation and severe weather patterns.
Despite emotional challenges like negative affect and fatigue, response inhibition can enhance divergent thinking by partially mediating the relationship between emotional states and creative potential. Frustration, when handled differently, can be a catalyst for invention and creativity.
A team of researchers compared 1,800 de novo proteins from fruit flies and humans with computer-generated proteins, revealing small but significant differences in their stability and solubility. The study suggests that natural selection may play a role in the early emergence of these proteins.
A novel metasurface-based approach achieves dynamic dual-mode modulation of THz waves by varying the wavelength of pumping light. The device can realize mode-selective or mode-unselective modulations on incident THz waves, offering high modulation pixel resolution and ultrafast modulation speed.
A new Northwestern Medicine study found that only 7% of Medicaid enrollees with opioid use disorder (OUD) received residential treatment, highlighting a significant gap in care. Residential treatment centers provide structured support and are considered one of the best treatments for severe substance use.
Researchers found that traditional handmade clay jars, called onggi, ferment kimchi faster and produce more beneficial bacteria due to their unique porous structure. The study highlights the connection between the earthenware's material properties and the fermentation process, providing new insights into ancient technology.
Researchers at HKU use single-cell transcriptomic data and phylostratigraphy to estimate the evolutionary origin of different cells in C. elegans. They find significant variation in transcriptome age among cell types, revealing insights into adaptation and developmental patterns.
Researchers at Stellenbosch University have discovered a crystalline substance that can readily give up water at temperatures as low as -70 °C. This finding has major implications for the development of materials designed to extract water from the atmosphere.
Researchers at Karolinska Institutet have discovered that a type of sugar molecule in blood is associated with the level of tau protein, a critical factor in severe dementia. Measuring blood glycan levels can predict Alzheimer's disease risk to 80% accuracy, almost a decade before symptoms appear.
Researchers have developed a novel 3D printing strategy that preserves the folding structure and molecular function of various biopolymers, enabling precise control over size and geometry at submicron resolution. The technique allows for the production of 3D biopolymeric architectures with functional integrity and biofunctions.
Acylceramides and protein-bound ceramides play a vital role in forming the oral barrier, similar to their function in the skin. Researchers found that these molecules protect against pathogens, chemicals, and allergens in mice.
A team approach to identifying patient cohorts using EHR data improves matching rates for certain e-phenotypes, such as infection and cancer. However, results vary across specialties and phenotypes, highlighting the need for expert collaboration in building accurate search queries.
The new AI system, AI-Descartes, combines theory and data to discover scientific equations, reproducing key parts of Langmuir's Nobel Prize-winning work. It also rediscovered Kepler's third law of planetary motion and approximated Einstein's relativistic time-dilation law.
A study published in Nature Water shows that boil water alerts significantly disrupt student learning, with unexcused absence rates increasing between 1% and 10%. Chronic exposure to contaminated water can have long-term impacts on a child's life.
A multidisciplinary research team has developed a promising virus-fighting protein using a quick, portable process that could be easily deployed at the source of a future virus outbreak. The protein, Griffithsin, disables a wide range of viruses, including COVID-19, and can be manufactured without living cells.
A study published in PLOS ONE warns of the dangers of coastal erosion on Libya's Cyrenaican coast, where numerous important archaeological sites are at risk. The research highlights increasing rates of erosion linked to human activities and climate change, emphasizing the need for detailed management and mitigation plans.
A nationwide study found that more experienced resident physicians are at risk of medical errors when working extended-duration shifts or long weekly hours, similar to first-year residents. The study calls for policy changes to limit work hours and extend safer training periods in the US.
Researchers at the University of Helsinki discovered a potential treatment for Alzheimer's disease and frontotemporal dementia using a PREP inhibitor. The PREP inhibitor reduced Tau accumulation and toxicity in cellular models and mice with tauopathy, improving cognitive skills.
Researchers tracked the evolution of Staphylococcus aureus in patients with eczema, discovering rapid mutations in a gene that enables the bacteria to grow faster on the skin. These findings could lead to targeted treatments by targeting variants of S. aureus associated with eczema symptoms.
A team of researchers has discovered that chromium(III) supplementation can regulate glucose metabolism in type 2 diabetic mice by targeting ATP synthase activity. This process improves mitochondrial deformation caused by high glucose levels and boosts glucose metabolism.
A new study finds that childhood symptoms of disordered eating are predictive of symptoms in adulthood for both Black and white women. Black women's symptoms were predicted by earlier ages compared to white women, suggesting cultural and psychological factors may influence symptom presentation.
A recent study published in the New England Journal of Medicine found that tranexamic acid did not reduce the need for blood transfusions or prevent maternal death in patients with increased risk for excessive bleeding after cesarean delivery. However, patients who received tranexamic acid had less need for additional medical intervent...
Researchers at University of California - San Diego found that vertebrates acquired a special protein from bacteria more than 500 million years ago. This discovery reveals a new piece of genetic material introduced from foreign bacterial genes, leading to unique functionality in vertebrate eyes.
Researchers developed ProTac, a soft robotic link with multimodal perception to improve human-robot interactions. The device incorporates tactile and proximity sensing capabilities, enabling robots to react safely and predictably to physical contact.
A novel clinical trial demonstrated that open-label placebo increased patient retention rates by 78% compared to methadone-only treatment. Participants also reported better sleep quality, with no significant differences found in other outcome measures. The study suggests that deception-free placebo treatment can provide valuable benefits.
Experts warn that the UK's free trade deal with CPTPP will make it harder to regulate tobacco and alcohol, ban products containing harmful pesticides, and enact policies to cut consumption of unhealthy food and drinks. A health impact assessment is needed to evaluate the potential benefits and harms of this deal.
Researchers at Salk Institute discover that dysfunctional mitochondria at synapses fail to meet energetic demand, supplying either too much or too little power and potentially causing working memory impairment with age. Adherence to the ultrastructural size principle is essential for avoiding cognitive decline in aging brains.
Scientists create B cell organoids to screen conjugate vaccine candidates, identifying antigen-specific antibodies with potential applications. The platform accelerates testing throughput, offering insights into the immune response to vaccines.
Researchers have developed an organoid-based method to assess the potency of glycoconjugate vaccines, speeding up the vaccine development process. This method uses tissue from a single mouse to create hundreds of immune organoids, allowing for the assessment of dozens or even hundreds of vaccine candidates in just four days.
A study analyzed Google Trends data to assess the impact of immunization and the COVID-19 pandemic on varicella cases in Europe. The research found a significant decrease in chickenpox cases across the region, suggesting suppressed transmission during the pandemic.
Researchers discovered a novel function of Claspin in the nutrition-induced signaling pathway, essential for activation of PI3K-PDK1-mTOR pathway and cell survival. This finding provides new targets for therapeutic interventions of metabolic disorders such as obesity, diabetes, and cancers.
A new study found that snowshoe hares' seasonal color swap is being disrupted by global warming, leaving them vulnerable to predators. Hares that wait too long to turn white may not survive the winter, highlighting the importance of timing in their survival.
A new study suggests that US food insecurity rates may be significantly higher than previously reported, with some areas experiencing rates over twice as high as national averages. The researchers recommend conducting surveys more frequently and asking about recent experiences to improve accuracy.
Scientists discovered that deleting a protein called sphingosine kinase 2 (SphK2) reprograms the tumor microenvironment, decreasing S1P levels and increasing p53 tumor suppressor gene accumulation. This creates an inhospitable environment for aggressive breast tumors.
A randomized clinical trial found that using smartphone apps for home monitoring after oncologic surgery leads to improved quality of recovery and equal patient satisfaction. The study compared this approach with conventional in-person follow-up, revealing no significant differences in these outcomes.
A new study found that Mexican American people who spoke only Spanish had worse neurologic outcomes three months after a stroke compared to those who spoke English or were bilingual. The study involved 1,096 participants and controlled for factors such as education and blood pressure.
Researchers found a partial response in a patient with pancreatic acinar cell carcinoma, as well as stable disease in 11 patients, when combining riluzole with sorafenib in a phase I trial. The combination was safe and tolerable, and further exploration of its potential is warranted.
Researchers found a 14.4% decline in new cancer diagnoses in 2020 compared to prior years, correlating with stay-at-home orders during the COVID-19 pandemic. The study estimates that around 200,000 people may have had undiagnosed or untreated cancer cases during this time.
Researchers at Vanderbilt University Medical Center have discovered a new way to measure the growth rate of precancerous clones of blood stem cells using a technique called PACER. The findings suggest that drugs targeting the gene TCL1A may be able to suppress clonal growth and associated cancers.
A Danish study has validated a dried blood spot test that can detect HIV, hepatitis B, and hepatitis C from a single drop of blood. The test uses existing hospital equipment and is suitable for places where needle-based testing is not practical or feasible.
New research suggests that disconnecting from work at home can boost a leader's energy and effectiveness the next day. Managers who ignored their work email at home felt more refreshed and were rated as effective leaders by their employees.
A new study found that the COVID-19 pandemic resulted in a significant increase in weekday screen time among school-aged children, with boosts of up to 1.35 hours per day. This finding suggests that children used screens to fill time previously spent at school or participating in extra-curricular activities.
A study found that cell competition between neural progenitor cells regulates brain size in mice, with top performers producing 30%-40% of neurons and losers producing only 1%-2%. The researchers identified Axin2 and p53 as key drivers of this process.
Researchers found that membership-based free shipping (MFS) can increase net customer revenue by up to 12.75%, as heavy buyers consolidate their spending after enrollment. Light buyers contribute the highest percentage change in revenue contribution, while heavy buyers may exploit free shipping benefits and lose money for retailers.
A Yale School of Public Health study found that older persons with mild cognitive impairment (MCI) who adopted positive age beliefs were 30% more likely to regain normal cognition compared to those with negative beliefs. These positive beliefs also enabled participants to recover their cognition up to two years earlier.
Dr. Roland Martin is honored for his work on immune mechanisms underlying multiple sclerosis, identifying key genes and nerve-insulating components targeted by immune attacks. His experimental therapy aims to make the immune system ignore those targets while preserving protective immunity.
Researchers identified a technique to detect abnormal protein deposits linked to Parkinson's disease, confirming its accuracy for early detection and characterisation. The α-synuclein seed amplification assay (αSyn-SAA) can identify people with Parkinson's disease and at-risk individuals prior to diagnosis.
Researchers confirmed a new protoplanet, HD 169142 b, orbiting a star 374 light years away. The planet is estimated to be about 37 astronomical units from its star and has carved an annular gap in the surrounding gas and dust disk.
Researchers at the University of Gothenburg have developed a new epoxy resin monomer based on isosorbide, a substance produced from glucose, to reduce contact allergies. The new monomer is far less allergenic and not based on Bisphenol A (BPA), a known endocrine disruptor.